How Can Computer Science Help Cancer Survivors Children?

Survival of childhood cancer has grown thanks to more effective but more aggressive treatments. As their life expectancy has increased, they have discovered important long-­‐term side effects that significantly limit their quality of life: cognitive, linguistic, physical, and social effects. The most significant problems are related to language and communication, which prevent the child from expressing himself properly, having difficulty finding the right word. This poster presents some possible computer mediated solutions to improve children cancer survivors’ quality of life

A bone-specific adipogenesis pathway in fat-free mice defines key origins and adaptations of bone marrow adipocytes with age and disease

Bone marrow adipocytes accumulate with age and in diverse disease states. However, their origins and adaptations in these conditions remain unclear, impairing our understanding of their context-specific endocrine functions and relationship with surrounding tissues. In this study, by analyzing bone and adipose tissues in the lipodystrophic \u27fat-free\u27 mouse, we define a novel, secondary adipogenesis pathway that relies on the recruitment of adiponectin-negative stromal progenitors. This pathway is unique to the bone marrow and is activated with age and in states of metabolic stress in the fat-free mouse model, resulting in the expansion of bone marrow adipocytes specialized for lipid storage with compromised lipid mobilization and cytokine expression within regions traditionally devoted to hematopoiesis. This finding further distinguishes bone marrow from peripheral adipocytes and contributes to our understanding of bone marrow adipocyte origins, adaptations, and relationships with surrounding tissues with age and disease

¿Cómo puede la Informática ayudar a los niños supervivientes de cáncer?

La supervivencia al cáncer infantil ha crecido gracias a tratamientos más efectivos, aunque más agresivos. A medida que ha aumentado su esperanza de vida, se han descubierto importantes efectos secundarios a largo plazo que limitan de manera significativa su calidad de vida: efectos cognitivos, lingüísticos, físicos, sociales. Los problemas más significativos están relacionados con el lenguaje y la comunicación, que impiden que el niño pueda expresarse de manera apropiada, teniendo dificultades para encontrar la palabra adecuada. Este póster presenta algunas posibles soluciones basadas en tecnologías TIC para mejorar la calidad de vida de los sobrevivientes de cáncer infantil

Bone Marrow Adipose Tissue: White, Brown or Beige?

From the Washington University Office of Undergraduate Research Digest (WUURD), Vol. 13, 05-01-2018. Published by the Office of Undergraduate Research. Joy Zalis Kiefer, Director of Undergraduate Research and Associate Dean in the College of Arts & Sciences; Lindsey Paunovich, Editor; Helen Human, Programs Manager and Assistant Dean in the College of Arts and Sciences Mentor(s): Erica L. Schellar and Clarissa S. Craf