1,547 research outputs found
La antropología en la planificación regional como elemento para la gestión integrada de recursos hídricos
Aquí se considera que los escritos de Ángel Palerm sobre Planificación, son una excelente herramienta de introducción a la Gestión Integrada de los Recursos Hídricos (GIRH). De allí que el objetivo de este trabajo sea la revisión e identificación de las principales propuestas palermianas sobre los conceptos y herramientas de cómo llevar a cabo la planificación y el desarrollo, con el fi n de presentarlos como una introducción y reflexión a la gestión integrada de los recursos hídricos (GIRH). Para lograrlo, se analiza el material y los documentos reunidos y publicados de Ángel Palerm sobre el tema, que datan desde 1950 hasta 1980, ordenando los casos, los conceptos, las herramientas y las formas metodológicas que Palerm utilizó para la planificación
Diseño de un escenario “en línea” para robots teleoperados desde internet
Se presentan conceptos relacionados con robots operados remotamente desde Internet, incluyendo su estructura física y computacional. Se describe la evolución de estos sistemas desde plataformas reales a virtuales e híbridas, y sus aplicaciones. Finalmente, se describen los elementos de un sistema hardware y software desarrollado para teleoperar y monitorear a través de un panel de control y una cámara CCD, a un robot desde un sitio Web
Biomimicry: natural systems in situ analysis aimed to rain water harvesting
Population growth has put a considerable pressure upon Mexico’s water supply, diminishing it in some regions of the country. The study of Biomimicry has less than 15 years of study, as a discipline aimed to analyses and study natural systems to emulate its characteristics and translate them into designs that can solve needs in a sustainable way. Using the latter to solve the former, it can be said that a possible way to harvest water from the environment to help the water supply; is using as inspiration of the way in which some plants native from Mexico’s dry regions obtain water from the environment in an efficient manner. This is possible since these plants have evolved to extract water micro particles and keep them in their inner reservoirs.Water is a valuable natural resource for life, but the poor management is making it scarce. This lack of care has created a series of social and technical problems, including the difficulties to distribute it to individual homes, particularly in Mexico. In order to solve such problems, it is necessary to find alternatives for its harvesting, care, distribution and use; allowing to reduce social stress, as well as allowing for a better water stewardship. One option is using Biomimicry and design as tools to find innovative, sustainable solutions. The conclusions of this current research project show how two different Mexican plants of notable importance, in economic and even gastronomical terms, had been analyzed through the eyes of the Biomimicry in order to extrapolate possible solutions of water harvesting and distribution. The aim of this paper is to discuss the results of such analyses
Optimization and application of a continuous flow photo-electro-Fenton system for the removal of pharmaceutical active compounds detected in irrigation water of Bogotá – Savanna (Colombia) Crops
In this study, a continuous flow photo-electro-Fenton (PEF) system was evaluated for its ability to remove pharmaceutically active compounds (PhACs) from irrigation water used in Bogotá-savanna crops. The PEF system consisted of dimensionally stable anode and graphite diffusion gas cathode, which were irradiated with LEDs. Firstly, the system was optimized using response surface methodology (RSM) in ultrapure water. The most favorable conditions for efficient generation of oxidants (the response variable) were found to be a flow rate of 210 mL/min, a current density of 15 mA/cm2, and an electrolyte concentration of 0.1 mol NaCl/L. Subsequently, model compounds of PhACs, including losartan (LOS), sulfamethoxazole (SMX), and diclofenac (DCF), were eliminated after only 10 min of treatment under the previously established conditions. After demonstrating the potential of the PEF system to eliminate PhACs, the system was applied to real irrigation water to evaluate the degradation of seven PhACs, namely carbamazepine (CBZ), sulfamethoxazole (SMX), ciprofloxacin (CIP), clarithromycin (CLR), diclofenac (DCF), valsartan (VAL), and trimethoprim (TMP). The results showed that after 30 min of treatment with the PEF system, the concentration of these compounds was drastically reduced remaining undetected. This demonstrates the high potential of the PEF system to reduce the presence of PhACs in irrigation water and associated environmental and food health risks
La impulsividad como factor determinante en el estado civil de estudiantes universitarios
Impulsivity is associated with several factors, in human behavior, so that in the present work it is carried out as an objective of identifying impulsivity in the university population that allows establishing the direct relationship with marital status in students. In the methodological design, the strategy is established, same as through the use of cross-sectional, non-experimental correlational research of a bibliographic field documentary type. In a population made up of 882 students, which belongs to 241 females and 641 males, it allowed the use of techniques such as the sociodemographic questionnaire, the Ramón y Cajal Impulse Control Scale (ECIRyC), which allowed to generate in their results, that of the total number of attendees, the percentage results are described with the following variables, the singles with (96%) being the largest group in terms of marital status, followed by those who said being married or in a free union corresponding to (2%), while the variables with a lower result were: commitment, divorce, dominant and currently in a relationship with a total of (0%), finally it can be stated that no differences were found in impulsivity and marital status in the participants, since in both cases impulsivity is most prevalent in subjects with separate marital status.La impulsividad se asocia a varios factores, en el comportamiento humano, de manera que en el presente trabajo se realiza como objetivo de identificar la impulsividad en la población universitaria que permitan establecer la relación directa con el estado civil en estudiantes, en el diseño metodológico se establece la estrategia, misma que mediante el uso de la investigación transversal, no experimental correlacional de tipo documental bibliográfico de campo. En una población constituida por 882 estudiantes, misma que pertenece a 241 femeninos y 641 masculinos permitió la utilización de técnicas como el cuestionario socio demográfico, la Escala de Control del Impulso Ramón y Cajal (ECIRyC), lo que permitió generar en sus resultados, que del total de participantes asistentes se describen los resultados porcentuales con las siguientes variables, los solteros con el (96%) siendo el grupo más grande en cuanto al estado civil, seguido de los que dijeron estar casados o unión libre correspondiendo al (2%), mientras que las variables con un menor resultado fueron: compromiso, divorcio, dominante y actualmente en pareja con un total de (0%), finalmente se puede referir que no se encontraron diferencias en impulsividad y estado civil en los participantes, puesto que en ambos casos los que más prevalece la impulsividad es en sujetos de estado civil separado
An Intrinsic Fiber-Optic Single Loop Micro-Displacement Sensor
A micro-displacement sensor consisting of a fiber-loop made with a tapered fiber is reported. The sensor operation is based on the interaction between the fundamental cladding mode propagating through the taper waist and higher order cladding modes excited when the taper is deformed to form a loop. As a result, a transmission spectrum with several notches is observed, where the notch wavelength resonances shift as a function of the loop diameter. The loop diameter is varied by the spatial displacement of one end of the fiber-loop attached to a linear translation stage. In a displacement range of 3.125 mm the maximum wavelength shift is 360.93 nm, with 0.116 nm/μm sensitivity. By using a 1,280 nm broadband low-power LED source and a single Ge-photodetector in a power transmission sensor setup, a sensitivity in the order of 2.7 nW/μm is obtained in ∼1 mm range. The proposed sensor is easy to implement and has a plenty of room to improve its performance
A promising novel formulation for articular cartilage regeneration: Preclinical evaluation of a treatment that produces SOX9 overexpression in human synovial fluid cells
Osteoarthritis (OA) is a chronic disorder of synovial joints, in which there is progressive softening and disintegration of the articular cartilage. OA is the most common form of arthritis, and is the primary cause of disability and impaired quality of life in the elderly. Despite considerable medical necessity, no treatment has yet been proven to act as a disease‑modifying agent that may halt or reverse the structural progression of OA. The replacement of the joint with a prosthesis appears to be the best option in the advanced stages of the disease. A formulation (BIOF2) for cartilage regeneration has been recently developed. The present study evaluated the effects of BIOF2 on gene expression in human cell cultures, followed by efficacy trials in three OA animal models. Human synovial fluid cells that were exposed to the formulation exhibited increased transcription factor SOX‑9 (SOX9; chondrogenic factor) expression, and decreased mimecan (mineralization inducer) and macrophage‑stimulating protein receptor (osteoclastogenic factor) expression. The intra‑articular application of BIOF2 in the animal models significantly increased cartilage thickness from 12 to 31% at 28 days, compared with articular cartilage treated with saline solution. The articular area and number of chondrocytes additionally increased significantly, maintaining an unaltered chondrocyte/mm2 proportion. Evaluation of the histological architecture additionally displayed a decrease in the grade of articular damage in the groups treated with BIOF2. In conclusion, BIOF2 has proven to be effective for treating OA in animal models, most likely due to SOX9 overexpression in articular cells
Anti‑inflammatory drugs and uterine cervical cancer cells: Antineoplastic effect of meclofenamic acid
Uterine cervical cancer (UCC) is one of the main causes of cancer-associated mortality in women. Inflammation has been identified as an important component of this neoplasia; in this context, anti-inflammatory drugs represent possible prophylactic and/or therapeutic alternatives that require further investigation. Anti-inflammatory drugs are common and each one may exhibit a different antineoplastic effect. As a result, the present study investigated different anti-inflammatory models of UCC in vitro and in vivo. Celecoxib, sulindac, nimesulide, dexamethasone, meclofenamic acid, flufenamic acid and mefenamic acid were tested in UCC HeLa, VIPA, INBL and SiHa cell lines. The cytotoxicity of the drugs was evaluated in vitro. Celecoxib, sulindac, nimesulide, mefenamic acid and flufenamic acid presented with slight to moderate toxicity (10–40% of cell death corresponding to 100 µM) in certain cell lines, while meclofenamic acid exhibited significant cytotoxicity in all essayed cell lines (50–90% of cell death corresponding to 100 µM). The meclofenamic acid was tested in murine models (immunodeficient and immunocompetent) of UCC, which manifested a significant reduction in tumor growth and increased mouse survival. It was demonstrated that of the evaluated anti-inflammatory drugs, meclofenamic acid was the most cytotoxic, with a significant antitumor effect in murine models. Subsequent studies are necessary to evaluate the clinical utility of this drug
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