Bottom-loading dilution refrigerator with ultra-high vacuum deposition capability

A Kelvinox 400 dilution refrigerator with the ability to load samples onto the mixing chamber from the bottom of the cryostat has been combined with an ultrahigh-vacuum (UHV) deposition chamber equipped with molecular beam sources. The liquid helium cooled sample transfer mechanism is used in a manner that allows films to be grown on substrates which are kept at temperatures of order 8K with chamber pressures in the 10^-9 to 10^-10 Torr range. This system facilitates the growth of quench-condensed ultrathin films which must always be kept below ~ 12K in a UHV environment during and after growth. Measurements can be made on the films down to millikelvin temperatures and in magnetic fields up to 15 T.Comment: 10 pages text, 1figur

Accurate Determination of Conformational Transitions in Oligomeric Membrane Proteins

The structural dynamics governing collective motions in oligomeric membrane proteins play key roles in vital biomolecular processes at cellular membranes. In this study, we present a structural refinement approach that combines solid-state NMR experiments and molecular simulations to accurately describe concerted conformational transitions identifying the overall structural, dynamical, and topological states of oligomeric membrane proteins. The accuracy of the structural ensembles generated with this method is shown to reach the statistical error limit, and is further demonstrated by correctly reproducing orthogonal NMR data. We demonstrate the accuracy of this approach by characterising the pentameric state of phospholamban, a key player in the regulation of calcium uptake in the sarcoplasmic reticulum, and by probing its dynamical activation upon phosphorylation. Our results underline the importance of using an ensemble approach to characterise the conformational transitions that are often responsible for the biological function of oligomeric membrane protein states

On minimal affinizations of representations of quantum groups

In this paper we study minimal affinizations of representations of quantum groups (generalizations of Kirillov-Reshetikhin modules of quantum affine algebras introduced by Chari). We prove that all minimal affinizations in types A, B, G are special in the sense of monomials. Although this property is not satisfied in general, we also prove an analog property for a large class of minimal affinization in types C, D, F. As an application, the Frenkel-Mukhin algorithm works for these modules. For minimal affinizations of type A, B we prove the thin property (the l-weight spaces are of dimension 1) and a conjecture of Nakai-Nakanishi (already known for type A). The proof of the special property is extended uniformly for more general quantum affinizations of quantum Kac-Moody algebras.Comment: 38 pages; references and additional results added. Accepted for publication in Communications in Mathematical Physic

Extended T-systems

We use the theory of q-characters to establish a number of short exact sequences in the category of finite-dimensional representations of the quantum affine groups of types A and B. That allows us to introduce a set of 3-term recurrence relations which contains the celebrated T-system as a special case.Comment: 36 pages, latex; v2: version to appear in Selecta Mathematic

Clone size distributions in networks of genetic similarity

We build networks of genetic similarity in which the nodes are organisms sampled from biological populations. The procedure is illustrated by constructing networks from genetic data of a marine clonal plant. An important feature in the networks is the presence of clone subgraphs, i.e. sets of organisms with identical genotype forming clones. As a first step to understand the dynamics that has shaped these networks, we point up a relationship between a particular degree distribution and the clone size distribution in the populations. We construct a dynamical model for the population dynamics, focussing on the dynamics of the clones, and solve it for the required distributions. Scale free and exponentially decaying forms are obtained depending on parameter values, the first type being obtained when clonal growth is the dominant process. Average distributions are dominated by the power law behavior presented by the fastest replicating populations.Comment: 17 pages, 4 figures. One figure improved and other minor changes. To appear in Physica

Rubidium and zirconium abundances in massive Galactic asymptotic giant branch stars revisited

Luminous Galactic OH/IR stars have been identified as massive (>4-5 M_s) AGB stars experiencing HBB and Li production. Their Rb abundances and [Rb/Zr] ratios derived from hydrostatic model atmospheres, are significantly higher than predictions from AGB nucleosynthesis models, posing a problem to our understanding of AGB evolution and nucleosynthesis. We report new Rb and Zr abundances in the full sample of massive Galactic AGB stars, previously studied with hydrostatic models, by using more realistic extended model atmospheres. We use a modified version of the spectral synthesis code Turbospectrum and consider the presence of a circumstellar envelope and radial wind. The Rb and Zr abundances are determined from the 7800 A Rb I resonant line and the 6474 A ZrO bandhead, respectively, and we explore the sensitivity of the derived abundances to variations of the stellar (Teff) and wind (M_loss, beta and vexp) parameters in the extended models. The Rb and Zr abundances derived from the best spectral fits are compared with the most recent AGB nucleosynthesis theoretical models. The new Rb abundances are much lower (even 1-2 dex) than those derived with the hydrostatic models, while the Zr abundances are similar. The Rb I line profile and Rb abundance are very sensitive to the M_loss rate but much less sensitive to variations of the wind velocity-law and the vexp(OH). We confirm the earlier preliminary results based on a smaller sample of massive O-rich AGB stars, that the use of extended atmosphere models can solve the discrepancy between the AGB nucleosynthesis theoretical models and the observations of Galactic massive AGB stars. The Rb abundances, however, are still strongly dependent of the M_loss, which is unknown in these AGB stars. Accurate M_loss rates in these massive Galactic AGB stars are needed in order to break the models degeneracy and get reliable Rb abundances in these stars.Comment: Accepted for publication in A&A, 14 pages, 12 figures, 4 table

HERA-B Framework for Online Calibration and Alignment

This paper describes the architecture and implementation of the HERA-B framework for online calibration and alignment. At HERA-B the performance of all trigger levels, including the online reconstruction, strongly depends on using the appropriate calibration and alignment constants, which might change during data taking. A system to monitor, recompute and distribute those constants to online processes has been integrated in the data acquisition and trigger systems.Comment: Submitted to NIM A. 4 figures, 15 page

Isolated elliptical galaxies in the local Universe

We have studied a sample of 89 very isolated, elliptical galaxies at z < 0.08 and compared their properties with elliptical galaxies located in a high-density environment such as the Coma supercluster. Our aim is to probe the role of environment on the morphological transformation and quenching of elliptical galaxies as a function of mass. In addition, we elucidate the nature of a particular set of blue and star-forming isolated ellipticals identified here. We study physical properties of ellipticals such as color, specific star formation rate, galaxy size, and stellar age, as a function of stellar mass and environment based on SDSS data. We analyze the blue star-forming isolated ellipticals in more detail, through photometric characterization using GALFIT, and infer their star formation history using STARLIGHT. Among the isolated ellipticals ~ 20% are blue, 8% are star forming, and ~ 10% are recently quenched, while among the Coma ellipticals ~ 8% are blue and just <= 1% are star forming or recently quenched. There are four isolated galaxies (~ 4.5%) that are blue and star forming at the same time. These galaxies, with masses between 7 x 10^9 and 2 x 10^10 h-2 M_sun, are also the youngest galaxies with light-weighted stellar ages <= 1 Gyr and exhibit bluer colors toward the galaxy center. Around 30-60% of their present-day luminosity, but only < 5% of their present-day mass, is due to star formation in the last 1 Gyr. The processes of morphological transformation and quenching seem to be in general independent of environment since most of elliptical galaxies are 'red and dead', although the transition to the red sequence should be faster for isolated ellipticals. In some cases, the isolated environment seems to propitiate the rejuvenation of ellipticals by recent (< 1 Gyr) cold gas accretion.Comment: 23 pages, 15 figures (16 pages and 9 figures without appendices). A&A, in pres

Meta-analysis of a very low proportion through adjusted wald confidence intervals

In this paper we will discuss the meta-analysis of one low proportion. It is well known, that there are several methods to perform the meta-analysis of one proportion, based on a linear combination of proportions or transformed proportions. However, in the context of a linear combination of binomial proportions has been proposed some approximate estimators with some improvements on low proportion estimation. In this paper we will show, with a simple adaptation, the possible contribution of several approximate adjusted Wald confidence intervals (CIs) for the meta-analysis of proportions. In the context of low proportions, a simulation study scenario is carried out to compare these CIs amongst themselves and with other available methods with respect to bias and coverage probabilities, using the fixed effect or the random-effects model. Pointing our interest in rare events (analogous for the abundant events) and taking into account the prevalence estimation of the Methicillin-resistant Staphylococcus aureus with mecc gene, we discuss the choice of the meta-analysis methods on this low proportion. The default meta-analysis methods of meta-analysis software programs are not always the best choice, in particular to the meta-analysis of one low proportion, where the methods including the adjusted Wald can outperform.publishe