Study for Wind Generation and CO2 Emission Reduction Applied to Street Lighting – Zacatecas, México

The widespread concern in developed and developing countries to generate clean and sus‐ tainable energy, has led to search for alternative sources for non polluting power generation such as wind power. Although electric power generating costs by harnessing the wind re‐ source are still higher than production with conventional plants, the difference is being re‐ duced, depending on the system capacity. Integrating wind power systems to distributed generation scheme, the efficiency of transmission and distribution may increase

Silicosis una enfermedad laboral silenciosa.

La silicosis es una enfermedad pulmonar incurable causada por la inhalación de polvo que contiene sílice cristalina libre. La sílice cristalina, es un componente natural que se encuentra en forma abundante, como en rocas, suelos, arena, granito, también se puede encontrar en el hormigón, el ladrillo, el mortero y en otros materiales para la construcción. Esta puede presentarse en varias formas, la más común es el cuarzo. El polvo del cuarzo es la sílice cristalina respirable, lo que significa que puede inhalarse al respirar. Su uso se ha extendido a un gran sector, aumentando con esto el número de trabajadores expuestos a riesgos por la acumulación de material particulado en los pulmones, dando origen a una enfermedad laboral. El siguiente artículo hace una reflexión acerca de cómo la sílice puede llegar afectar la salud de los trabajadores, de igual forma como su exposición y contacto puede llegar a generar una enfermedad laboral o la muerte a los trabajadores de diferente sector económico.Crystalline silica is a natural component found abundantly in rocks, soils, sand, granite, also found in concrete, brick, mortar and other building materials. Crystalline silica can occur in several forms, the most common being quartz. The quartz powder is respirable crystalline silica, which means that it can be inhaled when breathing. Its use has extended to a large sector of industrial processes, increasing with this the number of workers exposed to risks due to the accumulation of particulate material in the lungs, giving rise to a work-related illness called: Silicosis. The following article makes a reflection on how silica can affect the health of workers in the construction sector, as their exposure and contact generates a work-related illness death

Assembly of an artificial vision system to capture wear images in cutting tools

  En este trabajo se someterá a evaluación, la normativa ISO 8688-1 que rige el criterio de desgaste de herramientas. Existen varias maneras de observar o determinar el estado de vida de la herramienta, en este caso particular se determinará la vida útil de la herramienta de corte por medio de tratamientos de imágenes, obtenidas por un electro-microscopio, realizando un montaje minucioso para la obtención de las mismas. En esta publicación se especifican los detalles del montaje de sistema de visión para la captura de las imágenes. Palabras clave: Desgaste, norma ISO 8688-1, tratamiento de imágenes

Mitochondrial pH Nanosensors for Metabolic Profiling of Breast Cancer Cell Lines

We thank the company Nanogetic S.L. (Granada, Spain) for support with the synthesis of the SS peptides and the Centro de Instrumentacion Cientifica (CIC) of the Universidad de Granada for use of the TEM facilities.The main role of mitochondria, as pivotal organelles for cellular metabolism, is the production of energy (ATP) through an oxidative phosphorylation system. During this process, the electron transport chain creates a proton gradient that drives the synthesis of ATP. One of the main features of tumoral cells is their altered metabolism, providing alternative routes to enhance proliferation and survival. Hence, it is of utmost importance to understand the relationship between mitochondrial pH, tumoral metabolism, and cancer. In this manuscript, we develop a highly specific nanosensor to accurately measure the intramitochondrial pH using fluorescence lifetime imaging microscopy (FLIM). Importantly, we have applied this nanosensor to establish differences that may be hallmarks of different metabolic pathways in breast cancer cell models, leading to the characterization of different metabophenotypes.Spanish Ministerio de Ciencia, Innovacion y Universidades CTQ2014-56370-R CTQ2017-86568-REuropean Union (EU)Spanish Agencia Estatal de InvestigacionFundacion Ramon Arece

Resultados y alcances del proyecto de instalación de 32 plantas solares-fotovoltaicas en zonas marginadas del Estado de Zacatecas

Resumen— En este documento se presentan la revisión de los resultados y alcances que trajo consigo la instalación de 32 paquetes tecnológicos que proporcionan energía eléctrica en viviendas clasificadas como de muy alta marginación, luego de cumplir cinco años de su instalación. La investigación fue llevada a cabo principalmente mediante entrevistas y cuestionarios realizados a las familias beneficiadas. Los resultados arrojaron un cambio favorable a partir de un grupo de indicadores: sociales (avance educativo, acceso a los medios de telecomunicación y mejoras en la salud) económicos (mejora del ingreso o gasto de consumo), y medioambientales (una reducción considerable en el uso de leña, carbón y gasolina como su principal fuente de combustible), sin embargo, también se menciona el fracaso del proyecto, principalmente por la falta de seguimiento en los hogares. Finalmente, se establecen propuestas para futuros proyectos donde se busca garantizar la continuidad de éstos

Tree species diversity and utilities in a contracting lowland hillside rainforest fragment in Central Vietnam

Abstract Background Within the highly bio-diverse ‘Northern Vietnam Lowland Rain Forests Ecoregion’ only small, and mostly highly modified forestlands persist within vast exotic-species plantations. The aim of this study was to elucidate vegetation patterns of a secondary hillside rainforest remnant (elevation 120–330 m, 76 ha) as an outcome of natural processes, and anthropogenic processes linked to changing forest values. Methods In the rainforest remnant tree species and various bio-physical parameters (relating to soils and terrain) were surveyed on forty 20 m × 20 m sized plots. The forest's vegetation patterns and tree diversity were analysed using dendrograms, canonical correspondence analysis, and other statistical tools. Results Forest tree species richness was high (172 in the survey, 94 per hectare), including many endemic species (>16%; some recently described). Vegetation patterns and diversity were largely explained by topography, with colline/sub-montane species present mainly along hillside ridges, and lowland/humid-tropical species predominant on lower slopes. Scarcity of high-value timber species reflected past logging, whereas abundance of light-demanding species, and species valued for fruits, provided evidence of human-aided forest restoration and ‘enrichment’ in terms of useful trees. Exhaustion of sought-after forest products, and decreasing appreciation of non-wood products concurred with further encroachment of exotic plantations in between 2010 and 2015. Regeneration of rare tree species was reduced probably due to forest isolation. Conclusions Despite long-term anthropogenic influences, remnant forests in the lowlands of Vietnam can harbor high plant biodiversity, including many endangered species. Various successive future changes (vanishing species, generalist dominance, and associated forest structural-qualitative changes) are, however, expected to occur in small forest fragments. Lowland forest biodiversity can only be maintained if forest fragments maintain a certain size and/or are connected via corridors to larger forest networks. Preservation of the forests may be fostered using new economic incentive schemes

Analysis of decisional support systems and its application to business processes

RESUMEN: El presente trabajo, aborda en primer lugar, una revisión de la literatura del proceso de toma de decisiones y de los sistemas de apoyo a la toma de decisiones en las organizaciones. En segundo lugar, se realiza una aproximación teórica a los principales modelos para la toma de decisiones empresariales y teorías del management para, a continuación, exponer la metodología utilizada en el trabajo. Una vez realizado esto, se analizan los sistemas de ayuda a la toma de decisiones empresariales que más importancia han tomado en el ámbito empresarial. De acuerdo con ello, se lleva a cabo un estudio y descripción de las características distintivas de cada sistema, explicando cuáles son las aplicaciones que estos sistemas tienen en la toma de decisiones empresarial. Asimismo, se profundiza en la temática que es objeto de estudio, a través del análisis de casos reales de sistemas aplicados a nivel empresarial. Por último, se recogen las conclusiones del trabajo y se presentan las líneas futuras que permitirán seguir profundizando en la temática estudiada.ABSTRACT: This works first, a review of the literature of the decision-making process and systems to support decision making in organizations. Second, a theoretical approach to the main models for business decision-making and management theories to then present the methodology used in the work is done. Once done, the system helps the business decisions that have taken more importance in the business world are analyzed. Accordingly, it carried out a study and description of the distinctive characteristics of each system, explaining which applications these systems have in making business decisions are. It also delves into the subject that is being studied through the analysis of real cases applied to enterprise level systems. Finally, the conclusions are collected and the future lines that will further deepen the theme studied are presented.Máster en Dirección de Empresas (MBA

Breast Cancer Cell Subtypes Display Different Metabolic Phenotypes That Correlate with Their Clinical Classification

Recent studies on cancer cell metabolism have achieved notable breakthroughs that have led to a new scientific paradigm. How cancer cell metabolic reprogramming is orchestrated and the decisive role of this reprogramming in the oncogenic process and tumor adaptative evolution has been characterized at the molecular level. Despite this knowledge, it is essential to understand how cancer cells can metabolically respond as a living whole to ensure their survival and adaptation potential. In this work, we investigated whether different cancers and different subtypes display different metabolic phenotypes with a focus on breast cancer cell models representative of each clinical subtype. The potential results might have significant translational implications for diagnostic, prognostic and therapeutic applications.Metabolic reprogramming of cancer cells represents an orchestrated network of evolving molecular and functional adaptations during oncogenic progression. In particular, how metabolic reprogramming is orchestrated in breast cancer and its decisive role in the oncogenic process and tumor evolving adaptations are well consolidated at the molecular level. Nevertheless, potential correlations between functional metabolic features and breast cancer clinical classification still represent issues that have not been fully studied to date. Accordingly, we aimed to investigate whether breast cancer cell models representative of each clinical subtype might display different metabolic phenotypes that correlate with current clinical classifications. In the present work, functional metabolic profiling was performed for breast cancer cell models representative of each clinical subtype based on the combination of enzyme inhibitors for key metabolic pathways, and isotope-labeled tracing dynamic analysis. The results indicated the main metabolic phenotypes, so-called ‘metabophenotypes’, in terms of their dependency on glycolytic metabolism or their reliance on mitochondrial oxidative metabolism. The results showed that breast cancer cell subtypes display different metabophenotypes. Importantly, these metabophenotypes are clearly correlated with the current clinical classifications.Spanish Agencia Estatal de Investigación (Ministry of Science and Innovation)European Regional Development Fund [grant numbers CTQ2014-56370-R and CTQ2017-85658-R]Fundación Ramón ArecesInitiative "Solidaridad Entre Montañas

Analysis of a micro vertical-axis wind turbine by computational fluids simulation

The installed capacity of wind energy around the world using big horizontal-axis wind turbines (HAWT) has grown substantially in the last two decades. Likewise, research and development of vertical-axis wind turbines (VAWT) for small power applications has been increased during the last seven years. This paper presents the performance analysis related to the power output of a micro VAWT with three blades in helicoidal form, based on computacional fluids dynamics simulation (CFD), using Ansys Fluentr. In the analysis, several parameters related to the aerodynamic performance were varied, keeping constant the sweeping area. To compare results, a mathematical model was created in Matlabr, using the double-multiple streamtube method (DMST), which considers variations in relative wind speed through the wind turbine. Results from both, CFD simulation and DMST model, applied to the micro turbine are presented