Influencia de la rigidez de la subrasante y las capas granulares sobre la vida a fatiga de mezclas asfálticas

The mainly factors studied to predict fatigue life of hot mix asphalt-HMA in flexible pavements are the loading effect, type of test, compaction methods, design parameters of HMA (e.g., particle size and size distribution curve, fine content, type of bitumen) and the variables associated with the environment (mainly moisture, temperature, aging). This study evaluated through a computer simulation, the influence of the granular layers and subgrade on the fatigue life of asphalt layers in flexible pavement structures. Mechanics parameters of granular layers of subgrade, base and subbase were obtained using the mathematical equations currently used for this purpose in the world. The emphasis of the study was the city of Bogotá, where the average annual temperature is 14°C and soils predominantly clay, generally experience CBR magnitudes between 1% and 4%. General conclusion: stiffness of the granular layers and subgrade significantly affect the fatigue resistance of HMA mixtures. Likewise, the use of different equations reported in reference literature in order to characterize granular layers may vary the fatigue life between 4.6 and 48.5 times, varying the thickness of the pavement layers in the design.Cuando se intenta predecir la vida a fatiga de mezclas asfálticas en caliente, los principales factores que se evalúan son: el modo de carga y el tipo de ensayo aplicado, métodos de compactación de la muestra, parámetros de diseño de la mezcla (granulometría y tipo de agregado pétreo, contenido de finos, tipo de cemento asfáltico, etc.) y las variables asociadas al medio ambiente (principalmente humedad, temperatura, envejecimiento). En el presente estudio se evaluó, a través de simulación computacional, la influencia que tienen las capas granulares y la subrasante en la vida a fatiga de capas asfálticas de estructuras de pavimentos flexibles. Para caracterizar y determinar los parámetros mecánicos de las capas granulares de subrasante, base y subbase se emplearon las ecuaciones más utilizadas actualmente para tal fin en el mundo. La temperatura media anual promedio -TMAP- utilizada en las simulaciones fue de 14°C. Como conclusión general se reporta que la rigidez de las capas granulares y la subrasante inciden de manera significativa en la resistencia a fatiga de mezclas asfálticas. Así mismo, el empleo de una u otra ecuación reportada en la literatura de referencia para caracterizar capas granulares puede hacer variar la vida a fatiga entre 4,6 y 48,5 veces, modifi-cando el espesor de las capas del pavimento en su diseño

Non-motor symptom burden in patients with Parkinson's disease with impulse control disorders and compulsive behaviours : results from the COPPADIS cohort

The study was aimed at analysing the frequency of impulse control disorders (ICDs) and compulsive behaviours (CBs) in patients with Parkinson's disease (PD) and in control subjects (CS) as well as the relationship between ICDs/CBs and motor, nonmotor features and dopaminergic treatment in PD patients. Data came from COPPADIS-2015, an observational, descriptive, nationwide (Spain) study. We used the validated Questionnaire for Impulsive-Compulsive Disorders in Parkinson's Disease-Rating Scale (QUIP-RS) for ICD/CB screening. The association between demographic data and ICDs/CBs was analyzed in both groups. In PD, this relationship was evaluated using clinical features and treatment-related data. As result, 613 PD patients (mean age 62.47 ± 9.09 years, 59.87% men) and 179 CS (mean age 60.84 ± 8.33 years, 47.48% men) were included. ICDs and CBs were more frequent in PD (ICDs 12.7% vs. 1.6%, p < 0.001; CBs 7.18% vs. 1.67%, p = 0.01). PD patients had more frequent previous ICDs history, premorbid impulsive personality and antidepressant treatment (p < 0.05) compared with CS. In PD, patients with ICDs/CBs presented younger age at disease onset, more frequent history of previous ICDs and premorbid personality (p < 0.05), as well as higher comorbidity with nonmotor symptoms, including depression and poor quality of life. Treatment with dopamine agonists increased the risk of ICDs/CBs, being dose dependent (p < 0.05). As conclusions, ICDs and CBs were more frequent in patients with PD than in CS. More nonmotor symptoms were present in patients with PD who had ICDs/CBs compared with those without. Dopamine agonists have a prominent effect on ICDs/CBs, which could be influenced by dose

Mapeo curvas típicas, demanda de energía eléctrica del sector residencial, comercial e industrial de la ciudad de Medellín, usando redes neuronales artificiales y algoritmos de interpolación

One of the main problems that arise to model the electric power consumption ina certain place, consists on the extraction of the knowledge when this is stored in big volumes of information like, for example, historical registrations. In accordance with this representation, each fact and registration is made up of two components (t, P). t represents the time and P represent the electric power consumed at that instant. The N cases are registered daily; these represent t, P couples.The objective of this study is to map out the variable vector of t and Pperformance been F one of the functions. The model was made with Artificial Neural Network (ANN) which is a Multi Perceptron Layer (MPL). Another form of modeling is using Interpolation Algorithms(AI).Uno de los principales problemas que se tienen para modelar el consumo deenergía eléctrica en un lugar determinado, consiste en la extracción del conocimiento cuando éste se encuentra almacenado en grandes volúmenes de información como, por ejemplo, registros históricos. De acuerdo con esta representación, cada hecho ocurrido y registrado está compuesto por una pareja de componentes (t, P) en donde t representa el tiempo en el que se registró la muestra y P representa la potencia eléctrica consumida en ese instante. El registro diario cuenta con N casos que representa cada una de las parejas de estímulo-respuesta conocidas.El objetivo que se busca con este trabajo, entonces, consiste en hallar unafunción que permita mapear el vector de variables de entrada t al vector de variables  de salida P. F es una función cualquiera, en este caso el consumo de energía eléctrica.Su modelamiento con Redes Neuronales Artificiales (RNA) es un Perceptron Multi Capa (PMC). Otra forma de modelarlo es usando Algoritmos de Interpolación (AI)

Influence of Subgrade and Unbound Granular Layers Stiffness on Fatigue Life of Hot Mix Asphalts - HMA

The mainly factors studied to predict fatigue life of hot mix asphalt-HMA in flexible pavements are the loading effect, type of test, compaction methods, design parameters of HMA (e.g., particle size and size distribution curve, fine content, type of bitumen) and the variables associated with the environment (mainly moisture, temperature, aging). This study evaluated through a computer simulation, the influence of the granular layers and subgrade on the fatigue life of asphalt layers in flexible pavement structures. Mechanics parameters of granular layers of subgrade, base and subbase were obtained using the mathematical equations currently used for this purpose in the world. The emphasis of the study was the city of Bogotá, where the average annual temperature is 14°C and soils predominantly clay, generally experience CBR magnitudes between 1% and 4%. General conclusion: stiffness of the granular layers and subgrade significantly affect the fatigue resistance of HMA mixtures. Likewise, the use of different equations reported in reference literature in order to characterize granular layers may vary the fatigue life between 4.6 and 48.5 times, varying the thickness of the pavement layers in the design

Influencia de la Rigidez de la Subrasante y las Capas Granulares sobre la Vida a Fatiga de Mezclas Asfálticas.

The mainly factors studied to predict fatigue life of hot mix asphalt-HMA in flexible pavements are the loading effect, type of test, compaction methods, design parameters of HMA (e.g., particle size and size distribution curve, fine content, type of bitumen) and the variables associated with the environment (mainly moisture, temperature, aging). This study evaluated through a computer simulation, the influence of the granular layers and subgrade on the fatigue life of asphalt layers in flexible pavement structures. Mechanics parameters of granular layers of subgrade, base and subbase were obtained using the mathematical equations currently used for this purpose in the world. The emphasis of the study was the city of Bogotá, where the average annual temperature is 14°C and soils predominantly clay, generally experience CBR magnitudes between 1% and 4%. General conclusion: stiffness of the granular layers and subgrade significantly affect the fatigue resistance of HMA mixtures. Likewise, the use of different equations reported in reference literature in order to characterize granular layers may vary the fatigue life between 4.6 and 48.5 times, varying the thickness of the pavement layers in the design.Cuando se intenta predecir la vida a fatiga de mezclas asfálticas en caliente, los principales factores que se evalúan son: el modo de carga y el tipo de ensayo aplicado, métodos de compactación de la muestra, parámetros de diseño de la mezcla (granulometría y tipo de agregado pétreo, contenido de finos, tipo de cemen-to asfáltico, etc.) y las variables asociadas al medio ambiente (principalmente humedad, temperatura, envejecimiento). En el presente estudio se evaluó, a través de simulación computacional, la influencia que tienen las capas granulares y la subrasante en la vida a fatiga de capas asfálticas de estructuras de pavimentos flexibles. Para caracterizar y determinar los parámetros mecánicos de las capas granulares de subrasante, base y subbase se emplearon las ecuaciones más utiliza-das actualmente para tal fin en el mundo. La temperatura media anual promedio -TMAP- utilizada en las simulaciones fue de 14°C. Como conclusión general se reporta que la rigidez de las capas granulares y la subrasante inciden de manera significativa en la resistencia a fatiga de mezclas asfálticas. Así mismo, el empleo de una u otra ecuación reportada en la literatura de referencia para caracterizar capas granulares puede hacer variar la vida a fatiga entre 4,6 y 48,5 veces, modifi-cando el espesor de las capas del pavimento en su diseño

A Review of Warm Mix Asphalt Technology: Technical, Eco-nomical and Enviromental Aspects

In general terms, warm mix asphalt (WMA) technology presents a wide potential for successful use in road works construction projects. However, concerns remain regarding the durability and behavior of WMA mixtures in the long term, which need to be addressed. This review focuses on the technical, economic and environmental advantages and disadvantages. The review concludes that the main advantage, at the moment, of this technology concerns the environment. At the end of this work, the authors include certain recommendations for future works to continue strengthening the development of WMA technology.      En términos generales, la tecnología de mezcla asfáltica tibias (WMA por sus siglas en inglés) presenta un gran potencial para ser usa-da con éxito en proyectos de obras de construcción de obras viales. Sin embargo, aún existe preocupación en temas concernientes a la durabilidad y al comportamiento a largo de plazo de esta tecnología. Con base en una revisión bibliográfica, el artículo presenta los aspectos más importantes concernientes a la tecnología WMA. Se reportan las ventajas y desventajas técnicas, económicas y ambientales de utilizar esta tecnología reciente. Al final del documento los autores exponen algunas recomendaciones como apoyo para continuar fortaleciendo el desarrollo de la tecnología WMA

Physicochemical, Volatile, and Sensory Characterization of Promising Cherry Tomato (Solanum lycopersicum L.) Cultivars: Fresh Market Aptitudes of Pear and Round Fruits

Tomato (Solanum lycopersicum L.) is a well-known plant that belongs to the Solanaceae family. It is a widely consumed vegetable, either fresh or industrially processed. The aim of this study was to characterize and compare the morphology, main physicochemical parameters, volatile composition, and sensory quality of 8 cherry tomato cultivars: 4 pear cherry tomatoes (Angelle, Seychelles, Santyplum, and Dolcetini) and 4 round cherry tomatoes (Katalina, Sweet star, C-95, and Karelya) to be able to replace the most popular ones in markets (Angelle and Katalina). Morphological parameters had significant differences among cultivars, while in terms of total soluble solids and titratable acidity, Dolcetini could be an interesting substitute of Angelle in pear cherry cultivars, while in round ones C-95 would be the closest one. Regarding sugars, Santyplum was probably the cultivar which could be placed into a similar place to Angelle, while in round ones, C-95 was probably the cultivar closest to Katalina. Santyplum, Seychelles (pear type), and C-95 (round type) are likely to be the most interesting cherry cultivars in providing a real alternative to the most cultivated ones, in terms of volatile profile and concentration of the main volatile compounds. Descriptive sensory analysis revealed that Seychelles cultivar in 9 of the 15 attributes under study could be considered as the most similar cultivar to replace Angelle, while in round types no clear and direct relationship was found with any cultivar. Finally, consumers reported similar values for Angelle and Seychelles pear type cultivars, while round ones did not show significant differences. In summary, it can be stated that Seychelles and C-95 are the best alternatives of pear and round cherry cultivars, respectively, as compared to the reference cultivars, Angelle and Katalina

Vitamin D status is not associated with reproductive parameters in young Spanish men

European Union under grant agreement 675526-REP-BIOTECH-H2020-MSCA-Innovative Training Networks-201

Libro de Actas de las III Jornadas ScienCity 2020: Fomento de la Cultura Científica, Tecnológica y de Innovación en Ciudades Inteligentes

Editorial: Kindle Direct Publishing, Seattle, WS (USA)Actualmente, nuestras ciudades están experimentando una verdadera transformación digital que requiere una atención inmediata en energía, transporte, movilidad, comunicación, seguridad, educación, turismo y aspectos sociales, así como fomentar todas aquellas actuaciones que persigan mejorar la calidad de vida y el desarrollo económico-ambiental sostenible. ScienCity es un foro científico-tecnológico que pretende dar a conocer a la sociedad los conocimientos y tecnologías emergentes siendo investigados en las universidades, informar de experiencias, servicios e iniciativas puestas ya en marcha por instituciones y empresas, llegar hasta decisores políticos que podrían crear sinergias, incentivar la creación de ideas y posibilidades de desarrollo conjuntas, implicar y provocar la participación ciudadana.Junta de Andalucía, Universidad de Huelva y Consejo Social de la Universidad de Huelv

Non-motor symptoms burden, mood, and gait problems are the most significant factors contributing to a poor quality of life in non-demented Parkinson's disease patients: Results from the COPPADIS Study Cohort

[Objective] To identify factors related to a poor health-related and global quality of life (QoL) in a cohort of non-demented Parkinson's disease (PD) patients and compare to a control group.[Methods] The data correspond to the baseline evaluation of the COPPADIS-2015 Study, an observational, 5-year follow-up, multicenter, evaluation study. Three instruments were used to assess QoL: (1) the 39-item Parkinson's disease Questionnaire (PDQ-39), (2) a subjective rating of global QoL (PQ-10), and (3) the EUROHIS-QOL 8-item index (EUROHIS-QOL8). Multiple linear regression methods were used to evaluate the direct impact of different variables on these QoL measures.[Results] QoL was worse in PD patients (n = 692; 62.6 ± 8.9 years old, 60.3% males) than controls (n = 206; 61 ± 8.3 years old, 49.5% males): PDQ-39, 17.1 ± 13.5 vs 4.4 ± 6.3 (p < 0.0001); PQ-10, 7.3 ± 1.6 vs 8.1 ± 1.2 (p < 0.0001); EUROHIS-QOL8, 3.8 ± 0.6 vs 4.2 ± 0.5 (p < 0.0001). A high correlation was observed between PDQ-39 and Non-Motor Symptoms Scale (NMSS) (r = 0.72; p < 0.0001), and PDQ-39 and Beck Depression Inventory-II (BDI-II) (r = 0.65; p < 0.0001). For health-related QoL (PDQ-39), non-motor symptoms burden (NMSS), mood (BDI-II), and gait problems (Freezing Of Gait Questionnaire [FOGQ]) provided the highest contribution to the model (β = 0.32, 0.28, and 0.27, respectively; p < 0.0001); whereas mood and gait problems contributed the most to global QoL (PQ-10, β = -0.46 and −0.21, respectively; EUROHIS-QOL8, β = -0.44 and −0.23, respectively).[Conclusions] QoL is worse in PD patients than in controls. Mood, non-motor symptoms burden, and gait problems seem to be the most relevant factors affecting health-related and global perceived QoL in non-demented PD patients.Peer reviewe