Holocene Sedimentary Record and Coastal Evolution in the Makran Subduction Zone (Iran)

The western Makran coast displays evidence of surface uplift since at least the Late Pleistocene, but it remains uncertain whether this displacement is accommodated by creep on the subduction interface, or in a series of large earthquakes. Here, we address this problem by looking at the short-term (Holocene) history of continental vertical displacements recorded in the geomorphology and sedimentary succession of the Makran beaches. In the region of Chabahar (Southern Iran), we study two bay-beaches through the description, measurement and dating of 13 sedimentary sections with a combination of radiocarbon and Optically Stimulated Luminescence (OSL) dating. Our results show that lagoonal settings dominate the early Holocene of both studied beach sections. A flooding surface associated with the Holocene maximum transgression is followed by a prograding sequence of tidal and beach deposits. Coastal progradation is evidenced in Pozm Bay, where we observe a rapid buildup of the beach ridge succession (3.5 m/years lateral propagation over the last 1950 years). Dating of Beris Beach revealed high rates of uplift, comparable to the rates obtained from the nearby Late Pleistocene marine terraces. A 3150-year-old flooding surface within the sedimentary succession of Chabahar Bay was possibly caused by rapid subsidence during an earthquake. If true, this might indicate that the Western Makran does produce large earthquakes, similar to those that have occurred further east in the Pakistani Makran

Dating and morpho-stratigraphy of uplifted marine terraces in the Makran subduction zone (Iran)

The western part of the Makran subduction zone (Iran) is currently experiencing active surface uplift, as attested by the presence of emerged marine terraces along the coast. To better understand the uplift recorded by these terraces, we investigated seven localities along the Iranian Makran and we performed radiocarbon, 230Th∕U and optically stimulated luminescence (OSL) dating of the layers of marine sediments deposited on top of the terraces. This enabled us to correlate the terraces regionally and to assign them to different Quaternary sea-level highstands. Our results show east–west variations in surface uplift rates mostly between 0.05 and 1.2 mm yr−1. We detected a region of anomalously high uplift rate, where two MIS 3 terraces are emerged, but we are uncertain how to interpret these results in a geologically coherent context. Although it is presently not clear whether the uplift of the terraces is linked to the occurrence of large megathrust earthquakes, our results highlight rapid surface uplift for a subduction zone context and heterogeneous accumulation of deformation in the overriding plate

Crystal structure of the Actinomadura R39 DD-peptidase reveals new domains in penicillin-binding proteins.

Actinomadura sp. R39 produces an exocellular DD-peptidase/penicillin-binding protein (PBP) whose primary structure is similar to that of Escherichia coli PBP4. It is characterized by a high beta-lactam-binding activity (second order rate constant for the acylation of the active site serine by benzylpenicillin: k2/K = 300 mm(-1) s(-1)). The crystal structure of the DD-peptidase from Actinomadura R39 was solved at a resolution of 1.8 angstroms by single anomalous dispersion at the cobalt resonance wavelength. The structure is composed of three domains: a penicillin-binding domain similar to the penicillin-binding domain of E. coli PBP5 and two domains of unknown function. In most multimodular PBPs, additional domains are generally located at the C or N termini of the penicillin-binding domain. In R39, the other two domains are inserted in the penicillin-binding domain, between the SXXK and SXN motifs, in a manner similar to "Matryoshka dolls." One of these domains is composed of a five-stranded beta-sheet with two helices on one side, and the other domain is a double three-stranded beta-sheet inserted in the previous domain. Additionally, the 2.4-angstroms structure of the acyl-enzyme complex of R39 with nitrocefin reveals the absence of active site conformational change upon binding the beta-lactams

Structure and Function of BcpE2, the Most Promiscuous GH3-Family Glucose Scavenging Beta-Glucosidase.

peer reviewedCellulose being the most abundant polysaccharide on earth, beta-glucosidases hydrolyzing cello-oligosaccharides are key enzymes to fuel glycolysis in microorganisms developing on plant material. In Streptomyces scabiei, the causative agent of common scab in root and tuber crops, a genetic compensation phenomenon safeguards the loss of the gene encoding the cello-oligosaccharide hydrolase BglC by awakening the expression of alternative beta-glucosidases. Here, we revealed that the BglC compensating enzyme BcpE2 was the GH3-family beta-glucosidase that displayed the highest reported substrate promiscuity and was able to release the glucose moiety of all tested types of plant-derived heterosides (aryl β-glucosides, monolignol glucosides, cyanogenic glucosides, anthocyanosides, and coumarin heterosides). BcpE2 structure analysis highlighted a large cavity in the PA14 domain that covered the active site, and the high flexibility of this domain would allow proper adjustment of this cavity for disparate heterosides. The exceptional substrate promiscuity of BcpE2 provides microorganisms a versatile tool for scavenging glucose from plant-derived nutrients that widely vary in size and structure. Importantly, scopolin was the only substrate commonly hydrolyzed by both BglC and BcpE2, thereby generating the potent virulence inhibitor scopoletin. Next to fueling glycolysis, both enzymes would also fine-tune the strength of virulence. IMPORTANCE Plant decaying biomass is the most abundant provider of carbon sources for soil-dwelling microorganisms. To optimally evolve in such environmental niches, microorganisms possess an arsenal of hydrolytic enzymatic complexes to feed on the various types of polysaccharides, oligosaccharides, and monosaccharides. In this work, structural, enzymatic, and expression studies revealed the existence of a "swiss-army knife" enzyme, BcpE2, that was able to retrieve the glucose moiety of a multitude of plant-derived substrates that vary in size, structure, and origin. This enzyme would provide the microorganisms with a tool that would allow them to find nutrients from any type of plant-derived material

Argumentation et narration

À travers des contributions de diverses disciplines, cette enquête montre très concrètement que la puissance heuristique de la narration est un levier indispensable à toute pratique de l’argumentation. Elle montre aussi que si les deux registres concourent ensemble à une rationalité pleinement incarnée, ils ne se confondent jamais totalement

Théorie de l'argumentation et théorie du texte : quelques enjeux d'une approche textuelle de l'argumentation

La question du texte, négligée par la plupart des théories de l'argumentation, est ici abordée frontalement. L'étude est exemplifiée par le cas d'un genre journalistique de l'argumentation : une tribune libre écrite par un astro-physicien qui pose un certain nombre de problèmes intéressants. D'un point de vue méthodologique, la distinction de trois niveaux d'analyse est conforme aux grandes options de la linguistique textuelle : niveaux périodique micro-textuel de l'argumentation, niveau méso-textuel des « cellules argumentatives » et niveau macro-textuel du plan de texte. Ce dernier niveau ouvre sur la généricité complexe d'un texte qui relève à la fois d'un genre de l'opinion journalistique et du genre de la controverse polémique entre scientifiques à propos du traitement médiatique prématuré d'une découverte scientifique

Renforcement et dissociation des valeurs dans l'argumentation politique

Cet article s’interroge sur l’usage des valeurs dans l’argumentation politique. Cette dernière peut d’abord être le lieu d’un renforcement des valeurs et se rattacher en cela au genre épidictique de la rhétorique d’Aristote. Ce genre a été l’objet d’une longue dépréciation, puis, au XXe siècle, d’une « redécouverte » dont on retrace brièvement les étapes les plus marquantes. Le discours prononcé par le Général de Gaulle le jour de la capitulation allemande (8 mai 1945) est un exemple particulièrement frappant de rhétorique épidictique : il vise, par des procédures d’amplification, à exalter des valeurs prises dans leur dimension absolue et, ainsi, à rassembler une nation divisée et meurtrie. A l’inverse, l’argumentation politique implique bien souvent une dissociation des valeurs, ces dernières perdant alors leur caractère absolu. C’est ce cas de figure qu’illustre le débat parlementaire français de 1981 relatif à l’abolition de la peine de mort. Le droit à la vie, valeur extrêmement consensuelle in abstracto, se voit dissocié et réinterprété par les orateurs anti-abolitionnistes en fonction des buts que poursuit l’institution parlementaire