12,450 research outputs found

    Technology needs of advanced Earth observation spacecraft

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    Remote sensing missions were synthesized which could contribute significantly to the understanding of global environmental parameters. Instruments capable of sensing important land and sea parameters are combined with a large antenna designed to passively quantify surface emitted radiation at several wavelengths. A conceptual design for this large deployable antenna was developed. All subsystems required to make the antenna an autonomous spacecraft were conceptually designed. The entire package, including necessary orbit transfer propulsion, is folded to package within the Space Transportation System (STS) cargo bay. After separation, the antenna, its integral feed mast, radiometer receivers, power system, and other instruments are automatically deployed and transferred to the operational orbit. The design resulted in an antenna with a major antenna dimension of 120 meters, weighing 7650 kilograms, and operating at an altitude of 700 kilometers

    Escape path complexity and its context dependency in Pacific blue-eyes (Pseudomugil signifer)

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    The escape trajectories animals take following a predatory attack appear to show high degrees of apparent 'randomness' - a property that has been described as 'protean behaviour'. Here we present a method of quantifying the escape trajectories of individual animals using a path complexity approach. When fish (Pseudomugil signifer) were attacked either on their own or in groups, we find that an individual's path rapidly increases in entropy (our measure of complexity) following the attack. For individuals on their own, this entropy remains elevated (indicating a more random path) for a sustained period (10 seconds) after the attack, whilst it falls more quickly for individuals in groups. The entropy of the path is context dependent. When attacks towards single fish come from greater distances, a fish's path shows less complexity compared to attacks that come from short range. This context dependency effect did not exist, however, when individuals were in groups. Nor did the path complexity of individuals in groups depend on a fish's local density of neighbours. We separate out the components of speed and direction changes to determine which of these components contributes to the overall increase in path complexity following an attack. We found that both speed and direction measures contribute similarly to an individual's path's complexity in absolute terms. Our work highlights the adaptive behavioural tactics that animals use to avoid predators and also provides a novel method for quantifying the escape trajectories of animals.Comment: 9 page

    Alloying, de-alloying and reentrant alloying in (sub-)monolayer growth of Ag on Pt(111)

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    An in-situ nanoscopic investigation of the prototypical surface alloying system Ag/Pt(111) is reported. The morphology and the structure of the ultrathin Ag-Pt film is studied using Low Energy Electron Microscopy during growth at about 800 K. An amazingly rich dynamic behaviour is uncovered in which stress relieve plays a governing role. Initial growth leads to surface alloying with prolonged and retarded nucleation of ad-islands. Beyond 50% coverage de-alloying proceeds, joined by partial segregation of Pt towards the centre of large islands in violent processes. Upon coalescence the irregularly shaped vacancy clusters are filled by segregating Pt, which then take a compact shape (black spots). As a result at around 85% coverage the strain of the initially pseudo-morphological film is almost completely relieved and Pt-segregation is at its maximum. Further deposition of Ag leads to transient re-entrant alloying and recovery of the pseudo-morphological layer. The black spots persist even in/on several layers thick films. Ex-situ atomic force microscopy data confirm that these are constituted by probably amorphous Pt(-rich) structures. The (sub-)monolayer films are very much heterogeneous

    John Y. Templeton III: Pioneer of modern cardiothoracic surgery.

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    John Young Templeton III was born in 1917 in Portsmouth, Virginia, and graduated from Jefferson Medical College in 1941. He completed his residency training under Dr. John H. Gibbon, Jr., and was the first resident who worked on Gibbon\u27s heart-lung machine. After his training, he remained at Jefferson as an American Cancer Society fellow and Damon Runyon fellow and went on to become the fourth Samuel D. Gross Professor and Chair of the Department of Surgery in 1967. Dr. Templeton was the recipient of numerous grants and published over 80 papers in the field of cardiothoracic surgery. As a teacher and mentor, he was a beloved figure who placed great faith in his residents. He participated in over 60 professional societies, serving as president to many such as the Philadelphia Academy of Surgery and the Pennsylvania Association of Thoracic Surgery. He was also recognized through his many awards, in particular the John Y. Templeton III lectureship established in 1980 at Jefferson of whom Denton Cooley was the first lecturer. Dr. Templeton retired from practice in 1987. He is forever remembered as an important model of a modern surgeon evident in numerous academic achievements, the admiration and affection of his trainees, and the lives of patients that he had touched

    Building from Scratch: New Cities, Privatized Urbanism and the Spatial Restructuring of Johannesburg after Apartheid

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    By the start of the twenty‐first century, the once dominant historical downtown core of Johannesburg had lost its privileged status as the center of business and commercial activities, the metropolitan landscape having been restructured into an assemblage of sprawling, rival edge cities. Real estate developers have recently unveiled ambitious plans to build two completely new cities from scratch: Waterfall City and Lanseria Airport City (formerly called Cradle City) are master‐planned, holistically designed ‘satellite cities’ built on vacant land. While incorporating features found in earlier city‐building efforts, these two new self‐contained, privately‐managed cities operate outside the administrative reach of public authority and thus exemplify the global trend toward privatized urbanism. Waterfall City, located on land that has been owned by the same extended family for nearly 100 years, is spearheaded by a single corporate entity. Lanseria Airport City/Cradle City is a planned ‘aerotropolis’ surrounding the existing Lanseria airport at the northwest corner of the Johannesburg metropole. These two new private cities differ from earlier large‐scale urban projects because everything from basic infrastructure (including utilities, sewerage, and the installation and maintenance of roadways), landscaping, security services, the regulation of common spaces, and selling and branding the city are firmly in the hands of private profit‐making corporate entities and outside the mandate of public authorities.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/113120/1/ijur12180.pd

    United States v. Jones: Reviving the Property Foundation of the Fourth Amendment

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    United States v. Jones: Reviving the Property Foundation of the Fourth Amendment

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    Visualization of steps and surface reconstructions in Helium Ion Microscopy with atomic precision

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    Helium Ion Microscopy is known for its surface sensitivity and high lateral resolution. Here, we present results of a Helium Ion Microscopy based investigation of a surface confined alloy of Ag on Pt(111). Based on a change of the work function of 25\,meV across the atomically flat terraces we can distinguish Pt rich from Pt poor areas and visualize the single atomic layer high steps between the terraces. Furthermore, dechanneling contrast has been utilized to measure the periodicity of the hcp/fcc pattern formed in the 2--3 layers thick Ag/Pt alloy film. A periodicity of 6.65\,nm along the ⟹11‟2⟩\langle\overline{11}2\rangle surface direction has been measured. In terms of crystallography a hcp domain is obtained through a lateral displacement of a part of the outermost layer by 1/31/\sqrt{3} of a nearest neighbour spacing along ⟹11‟2⟩\langle\overline{11}2\rangle. This periodicity is measured with atomic precision: coincidence between the Ag and the Pt lattices is observed for 23 Ag atoms on 24 Pt atoms. The findings are perfectly in line with results obtained with Low Energy Electron Microscopy and Phase Contrast Atomic Force Microscopy.Comment: 15 pages, 7 figure

    Cosmological Density Perturbations with a Scale-Dependent Newton's G

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    We explore possible cosmological consequences of a running Newton's constant G(□) G ( \Box ) , as suggested by the non-trivial ultraviolet fixed point scenario in the quantum field-theoretic treatment of Einstein gravity with a cosmological constant term. In particular we focus here on what possible effects the scale-dependent coupling might have on large scale cosmological density perturbations. Starting from a set of manifestly covariant effective field equations derived earlier, we systematically develop the linear theory of density perturbations for a non-relativistic, pressure-less fluid. The result is a modified equation for the matter density contrast, which can be solved and thus provides an estimate for the growth index parameter γ\gamma in the presence of a running GG. We complete our analysis by comparing the fully relativistic treatment with the corresponding results for the non-relativistic (Newtonian) case, the latter also with a weakly scale dependent GG.Comment: 54 pages, 4 figure

    Innate immune receptor NOD2 mediates LGR5+ intestinal stem cell protection against ROS cytotoxicity via mitophagy stimulation

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    International audienceThe nucleotide-binding oligomerization domain-containing protein 2 (NOD2) agonist muramyl dipeptide (MDP), a peptidoglycan motif common to all bacteria, supports leucine-rich repeat-containing G protein-coupled receptor 5 (LGR5)+ intestinal stem cell (ISC) survival through NOD2 activation upon an otherwise lethal oxidative stress-mediated signal. However, the underlying protective mechanisms remain unknown. Here, using irradiation as stressor and primarily murine-derived intestinal organoids as a model system, we show that MDP induced a significant reduction of total and mitochondrial reactive oxygen species (ROS) within ISCs, which was associated with mitophagy induction. ATG16L1 knockout (KO) and NOD2 KO organoids did not benefit from the MDP-induced cytoprotection. We confirmed the MDP-dependent induction of ISC mitophagy upon stress in vivo. These findings elucidate the NOD2-mediated mechanism of cytoprotection involving the clearance of the lethal excess of ROS molecules through mitophagy, triggered by the coordinated activation of NOD2 and ATG16L1 by a nuclear factor ÎșB (NF-ÎșB)-independent pathway
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