Correlation of laser velocimeter measurements over a wing with results of two prediction techniques

The flow field at the center line of an unswept wing with an aspect ratio of eight was determined using a two dimensional viscous flow prediction technique for the flow field calculation, and a three dimensional potential flow panel method to evaluate the degree of two dimensionality achieved at the wing center line. The analysis was made to provide an acceptable reference for comparison with velocity measurements obtained from a fringe type laser velocimeter optics systems operating in the backscatter mode in the Langley V/STOL tunnel. Good agreement between laser velocimeter measurements and theoretical results indicate that both methods provide a true representation of the velocity field about the wing at angles of attack of 0.6 and 4.75 deg

Laser velocimeter survey about a NACA 0012 wing at low angles of attack

An investigation was conducted in the Langley V/STOL tunnel with a laser velocimeter to obtain measurements of airflow velocities about a wing at low angles of attack. The applicability of the laser velocimeter technique for this purpose in the V/STOL tunnel was demonstrated in this investigation with measurement precision bias calculated at -1.33 percent to 0.91 percent and a random uncertainty calculated at + or - 0.47 percent. Free stream measurements were obtained with this device and compared with velocity calculations from pitot static probe data taken near the laser velocimeter measurement location. The two measurements were in agreement to within 1 percent. Velocity measurement results about the centerline at 0.6 degrees angle of attack were typically those expected. At 4.75 degrees, the velocity measurements indicated that a short laminar separation bubble existed near the leading edge with an oscillating shear layer

Has Behavioral Science Tumbled Through the Biological Looking Glass? Will Brief, Evidence-Based Training Return It From the Rabbit Hole?

Time constraints and professional demands leave practicing professionals unlikely to enroll in extended training such as a semester-long graduate course. Thus, the three-hour continuing education format has become a standard for those in practice. One may ask what sorts of training strategies optimize that format. To explore that, a three hour training program for seventy-six practicing mental health professionals, most of whom self-identified as psychologists, was devised. It made use of primarily antecedent techniques that have been shown to bring about changed perceptions on a number of topics. Content focused on two areas of importance to behavior analysts, the culture’s increasing acceptance of the biological causation model of disorders such as attentiondeficit hyperactivity disorder (ADHD), unipolar depression, anxiety disorders, and schizophrenia, and the field’s increasing reliance on medications, often to the exclusion of behavioral methods. Pre-post assessment showed that participants had changed their thinking regarding the two content areas. The authors caution that participants’ changed opinions may serve as setting events to changes in practice, but those changes are verbal. One must not assume changes in practice techniques will automatically occur

Novel APC mutations in Czech and Slovak FAP families: clinical and genetic aspects

BACKGROUND: Germline mutations in the adenomatous polyposis gene (APC) result in familial adenomatous polyposis (FAP). FAP is an autosomal dominantly inherited disorder predisposing to colorectal cancer. Typical FAP is characterized by hundreds to thousands of colorectal adenomatous polyps and by several extracolonic manifestations. An attenuated form of polyposis (AFAP) is characterized by less than 100 adenomas and later onset of the disease. METHODS: Here, we analyzed the APC gene for germline mutations in 59 Czech and 15 Slovak FAP patients. In addition, 50 apparently APC mutation negative Czech probands and 3 probands of Slovak origin were screened for large deletions encompassing the APC gene. Mutation screening was performed using denaturing gradient gel electrophoresis and/or protein truncation test. DNA fragments showing an aberrant electrophoretic banding pattern were sequenced. Screening for large deletions was performed by multiplex ligation dependent probe amplification. The extent of deletions was analyzed using following microsatellite markers: D5S299, D5S82, D5S134 and D5S346. RESULTS: In the set of Czech and Slovak patients, we identified 46 germline mutations among 74 unrelated probands. Total mutation capture is 62,2% including large deletions. Thirty seven mutations were detected in 49 patients presenting a classical FAP phenotype (75,5%) and 9 mutations in 25 patients with attenuated FAP (36%). We report 20 novel germline APC mutations and 3 large deletions (6%) encompassing the whole-gene deletions and/or exon 14 deletion. In the patients with novel mutations, correlations of the mutation localization are discussed in context of the classical and/or attenuated phenotype of the disease. CONCLUSION: The results of the molecular genetic testing are used both in the establishment of the predictive diagnosis and in the clinical management of patients. In some cases this study has also shown the difficulty to classify clinically between the classical and the attenuated form of FAP according to the established criteria. Interfamilial and/or intrafamilial phenotype variability was also confirmed in some cases which did not fit well with predicted genotype-phenotype correlation. All these findings have to be taken into consideration both in the genetic counselling and in the patient care

Proceedings of the 13th annual conference of INEBRIA

CITATION: Watson, R., et al. 2016. Proceedings of the 13th annual conference of INEBRIA. Addiction Science & Clinical Practice, 11:13, doi:10.1186/s13722-016-0062-9.The original publication is available at https://ascpjournal.biomedcentral.comENGLISH SUMMARY : Meeting abstracts.https://ascpjournal.biomedcentral.com/articles/10.1186/s13722-016-0062-9Publisher's versio

Modification of the outside characteristics of a diesel engine by means of change of fuel injection parameters

W opracowaniu opisano zagadnienia sterowania parametrami pracy wysokociśnieniowego układu wtryskowego silników o zapłonie samoczynnym, stosowanego w ciągnikach rolniczych. Umiejętna modyfikacja tego sterowania na drodze czysto elektronicznej przynosi znaczącą poprawę wszystkich charakterystyk eksploatacyjnych ciągnika. Powodzenie adaptacji zależy jednak od profesjonalizmu wykonawcy i klasy aparatury pomiarowej. Wydaje się, że tego typu działania wypełniają znaczącą niszę na rynku ciągników rolniczych i mogą stanowić uzupełnienie oferty fabrycznej producentów silników do pojazdów użytkowych. Dotychczasowe, z powodzeniem przeprowadzone modyfikacje dowodzą, że w nowoczesnych silnikach o zapłonie samoczynnym tkwią znaczne rezerwy mocy i momentu obrotowego. Trzeba zaznaczyć, że nie odbywa się to kosztem charakterystyk ekologicznych silnika.The paper presents issues concerning control of operation parameters of a high-pressure injection system of diesel engines used in farm tractors. Skilful modification of this control by means of electronics brings a considerable improvement of all exploitation characteristics of a tractor. However, success of adaptation depends on the producer’s professionalism and the class of measuring apparatus. It seems that such activities fill in a considerable gap on the farm tractors market and may constitute complementation of the factory offer of the producers of engines for utility vehicles. Successful modifications which have been carried out so far prove that modern diesel engines have high power and rotational moment reserves. It must be emphasised that it influences ecological parameters of the engine