7 research outputs found
Phytochemical analysis and antimicrobial activity of different extracts of <i>Orthosiphon pallidus</i>
Phytochemical analysis and antimicrobial activity of different extracts of Orthosiphon pallidus
No abstract is availabl
Phytochemistry and Pharmacology of Moringa oleifera Lam
Moringa oleifera Lam. or munga is one of the most
important plant widely cultivated in India. It belongs
to family Moringaceae. This plant is widely used as nutritional
herb and contains valuable pharmacological
action like anti-asthmatic, anti-diabetic, hepatoprotective,
anti-inflammatory, anti- fertility, anti-cancer, antimicrobial,
anti-oxidant, cardiovascular, anti-ulcer, CNS
activity, anti-allergic, wound healing, analgesic, and
antipyretic activity, Moringa oleifera Lam. The plant is
also known as Horse - radish tree, Drumstick tree. Every
part of this plant contains a valuable medicinal feature.
It contain rich source of the vitamin A, vitamin C and
milk protein. Different types of active phytoconstituents
like alkaloids, protein, quinine, saponins, flavonoids,
tannin, steroids, glycosides, fixed oil and fats are
present. This plant is also found in the tropical regions.
Some other constituents are niazinin A, niazinin B and
niazimicin A, niaziminin B. The present review discusses
the phytochemical composition, medicinal uses &
pharmacological activity of this plant
Methanolic Extract of Plumbago Zeylanica - A Remarkable Antibacterial Agent Against Many Human and Agricultural Pathogens
Objectives: The current investigation was carried out to determine the cytotoxic and the antimicrobial activities of methanolic extracts of Plumbago zeylanica. Methods: The stems, leaves, and whole plants were air dried and extracted with methanol by using a Soxhlet extractor for 72 hours at 55 - 60°C. The antimicrobial activities were determined from the zones of inhibition, which were measured by using the agar well diffusion method, and the cytotoxicity assays were performed using the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay method. Results: The methanolic extracts of the stem and the leaves of Plumbago zeylanica were tested against six bacterial species and nine fungal species, and both extracts showed antimicrobial activity in a dose-dependent manner. The leaf extract of Plumbago zeylanica showed maximum antimicrobial activity against both Staphylococcus aureus sub sp aureus and Fusarium oxysporum. The stem extract was found to be more antimicrobial against the Pseudomonas aeruginosa and the Penicillium expansum species. MTT assays were used to test the cytotoxicity of the whole plant extract in the HCT-116 and the K-562 cell lines, and that extract was shown to have weak cytotoxicity in both cell lines. Conclusion: In the present study, the methanolic stem extracts of Plumbago zeylanica were found to possess remarkable antibacterial activities against many human and agricultural pathogens. The extracts were also found to possess significant antifungal activities, but the antifungal activities were less than the antibacterial activities. Finally, the extracts were found to have weak cytotoxicities in the HCT-116 and the K-562 cell lines