186 research outputs found
Managerial cost accounting for a technical information center
Managerial cost accounting system for information retrieval center
Improvements to a Class of Distance Matrix Methods for Inferring Species Trees from Gene Trees
Abstract Among the methods currently available for inferring species trees from gene trees, the GLASS method of Mossel and Roch (2010), the Shallowest Divergence (SD) method of Maddison and Knowles (2006), the STEAC method of Liu et al. (2009), and a related method that we call Minimum Average Coalescence (MAC) are computationally efficient and provide branch length estimates. Further, GLASS and STEAC have been shown to be consistent estimators of tree topology under a multispecies coalescent model. However, divergence time estimates obtained with these methods are all systematically biased under the model because the pairwise interspecific gene divergence times on which they rely must be more ancient than the species divergence time. Jewett and Rosenberg (2012) derived an expression for the bias of GLASS and used it to propose an improved method that they termed iGLASS. Here, we derive the biases of SD, STEAC, and MAC, and we propose improved analogues of these methods that we call iSD, iSTEAC, and iMAC. We conduct simulations to compare the performance of these methods with their original counterparts and with GLASS and iGLASS, finding that each of them decreases the bias and mean squared error of pairwise divergence time estimates. The new methods can therefore contribute to improvements in the estimation of species trees from information on gene trees.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/98441/1/cmb%2E2012%2E0042.pd
The Role of the Environment in Chaotic Quantum Dynamics
We study how the interaction with an external incoherent environment induces
a crossover from quantum to classical behavior for a particle whose classical
motion is chaotic. Posing the problem in the semiclassical regime, we find that
noise produced by the bath coupling rather than dissipation is primarily
responsible for the dephasing that results in the ``classicalization'' of the
particle. We find that the bath directly alters the phase space structures that
signal the onset of classical chaos. This dephasing is shown to have a
semiclassical interpretation: the noise renders the interfering paths
indistinguishable and therefore incoherent. The noise is also shown to
contribute to the quantum inhibition of mixing by creating new paths that
interfere coherently.Comment: 10 pages RevTex. Three figures in Postscript as a uuencoded
compressed tar file have been submitted as wel
The Inhibition of Mixing in Chaotic Quantum Dynamics
We study the quantum chaotic dynamics of an initially well-localized wave
packet in a cosine potential perturbed by an external time-dependent force. For
our choice of initial condition and with small but finite, we find that
the wave packet behaves classically (meaning that the quantum behavior is
indistinguishable from that of the analogous classical system) as long as the
motion is confined to the interior of the remnant separatrix of the cosine
potential. Once the classical motion becomes unbounded, however, we find that
quantum interference effects dominate. This interference leads to a long-lived
accumulation of quantum amplitude on top of the cosine barrier. This pinning of
the amplitude on the barrier is a dynamic mechanism for the quantum inhibition
of classical mixing.Comment: 20 pages, RevTeX format with 6 Postscript figures appended in
uuencoded tar.Z forma
Recurrences in Driven Quantum Systems
We consider an initially bound quantum particle subject to an external
time-dependent field. When the external field is large, the particle shows a
tendency to repeatedly return to its initial state, irrespective of whether the
frequency of the field is sufficient for escape from the well. These
recurrences, which are absent in a classical calculation, arise from the system
evolving primarily like a free particle in the external field.Comment: 10 pages in RevTeX format, with three PS files appende
Characteristics of Quantum-Classical Correspondence for Two Interacting Spins
The conditions of quantum-classical correspondence for a system of two
interacting spins are investigated. Differences between quantum expectation
values and classical Liouville averages are examined for both regular and
chaotic dynamics well beyond the short-time regime of narrow states. We find
that quantum-classical differences initially grow exponentially with a
characteristic exponent consistently larger than the largest Lyapunov exponent.
We provide numerical evidence that the time of the break between the quantum
and classical predictions scales as log(), where is
a characteristic system action. However, this log break-time rule applies only
while the quantum-classical deviations are smaller than order hbar. We find
that the quantum observables remain well approximated by classical Liouville
averages over long times even for the chaotic motions of a few
degree-of-freedom system. To obtain this correspondence it is not necessary to
introduce the decoherence effects of a many degree-of-freedom environment.Comment: New introduction, accepted in Phys Rev A (May 2001 issue), 12 latex
figures, 3 ps figure
Decoherence, Chaos, and the Correspondence Principle
We present evidence that decoherence can produce a smooth
quantum-to-classical transition in nonlinear dynamical systems. High-resolution
tracking of quantum and classical evolutions reveals differences in expectation
values of corresponding observables. Solutions of master equations demonstrate
that decoherence destroys quantum interference in Wigner distributions and
washes out fine structure in classical distributions bringing the two closer
together. Correspondence between quantum and classical expectation values is
also re-established.Comment: 4 pages, 2 figures (color figures embedded at low resolution), uses
RevTeX plus macro (included). Phys. Rev. Lett. (in press
Identification of a Forskolin-Like Molecule in Human Renal Cysts
Renal cyst enlargement is increased by adenosine cAMP, which is produced within mural epithelial cells. In a search for modulators of cAMP synthesis cyst fluids from 18 patients with autosomal dominant or recessive polycystic kidney disease (PKD) were analyzed, and in 15 of them, a stable lipophilic molecule that increased cAMP levels, stimulated transepithelial chloride and fluid secretion, and promoted the proliferation of human cyst epithelial cells was characterized. With the use of HPLC-mass spectrometry, a bioactive lipid with the same mass spectral fingerprint, the same chromatographic retention time, and the same biologic properties as forskolin, a widely known, potent adenylyl cyclase agonist, has been isolated and identified within the cyst fluid. Forskolin is synthesized by the plant Coleus forskohlii, but its appearance or compounds like it have not been reported in animals. The origin of forskolin in patients with PKD was not revealed by this study. Synthesis by mural cyst epithelial cells or an exogenous source are the most likely possibilities. Forskolin is sold for weight management and as a cardiovascular tonic in health stores and through the Worldwide Web. It is concluded that forskolin may have a role in promoting the enlargement of cysts in autosomal dominant PKD and recommended that patients avoid oral and parenteral preparations that contain this compound
Properties of the binding sites for the sn-1 and sn-2 acyl chains on the phosphatidylinositol transfer protein from bovine brain
Catalytic cracking performance of alkaline-treated zeolite Beta in the terms of acid sites properties and their accessibility
The zeolite Beta is considered as a promising additive for FCC catalyst in diesel oil production. In this article, it is shown that hierarchical zeolite Beta obtained by an optimized desilication procedure increases diesel and propylene yields during gas oil cracking reaction. The alkaline treatment of zeolite Beta (Si/Al = 22) by desilication with NaOH and NaOH&TBAOH was investigated. The catalytic performance improvement of desilicated zeolite Beta has been rationalized by deep characterization of the samples including X-ray diffraction, low-temperature adsorption of nitrogen, solid-state 29Si MAS NMR and IR studies of acidity. Finally, the catalytic performance of the zeolites Beta was evaluated in the cracking of n-decane, 1,3,5-tri-iso-propylbenzene, and vacuum gas oil. It was found that desilication with NaOH&TBAOH ensures the more uniform intracrystalline mesoporosity with the formation of narrower mesopores, while preserving full crystallinity resulting in catalysts with the most appropriated acidity and then with better catalytic performance.Also, M.C.I.L., J.M.T. and F.R. thank financial support from the Spanish Ministry of Economy and Competitiveness through the Severo Ochoa program (SEV-2012-0267) as well as operating grants Consolider Ingenio Multicat (CSD-2009-00050) and MAT-2012-3856-0O2-01.Tarach, K.; Gora-Marek, K.; Tekla, J.; Brylewska, K.; Datka, J.; Mlekodaj, K.; Makowski, W.... (2014). Catalytic cracking performance of alkaline-treated zeolite Beta in the terms of acid sites properties and their accessibility. Journal of Catalysis. 312:46-57. https://doi.org/10.1016/j.jcat.2014.01.009S465731
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