3,858 research outputs found
A simple low-SAR technique for chemical-shift selection with high-field spin-echo imaging
We have discovered a simple and highly robust method for removal of chemical shift artifact in spin-echo MR images, which simultaneously decreases the radiofrequency power deposition (specific absorption rate). The method is demonstrated in spin-echo echo-planar imaging brain images acquired at 7 T, with complete suppression of scalp fat signal. When excitation and refocusing pulses are sufficiently different in duration, and thus also different in the amplitude of their slice-select gradients, a spatial mismatch is produced between the fat slices excited and refocused, with no overlap. Because no additional radiofrequency pulse is used to suppress fat, the specific absorption rate is significantly reduced compared with conventional approaches. This enables greater volume coverage per unit time, well suited for functional and diffusion studies using spin-echo echo-planar imaging. Moreover, the method can be generally applied to any sequence involving slice-selective excitation and at least one slice-selective refocusing pulse at high magnetic field strengths. The method is more efficient than gradient reversal methods and more robust against inhomogeneities of the static (polarizing) field (B0)
Quantum key distribution using non-classical photon number correlations in macroscopic light pulses
We propose a new scheme for quantum key distribution using macroscopic
non-classical pulses of light having of the order 10^6 photons per pulse.
Sub-shot-noise quantum correlation between the two polarization modes in a
pulse gives the necessary sensitivity to eavesdropping that ensures the
security of the protocol. We consider pulses of two-mode squeezed light
generated by a type-II seeded parametric amplification process. We analyze the
security of the system in terms of the effect of an eavesdropper on the bit
error rates for the legitimate parties in the key distribution system. We also
consider the effects of imperfect detectors and lossy channels on the security
of the scheme.Comment: Modifications:added new eavesdropping attack, added more references
Submitted to Physical Review A [email protected]
Ion detection in the photoionization of a Rb Bose-Einstein condensate
Two-photon ionization of Rubidium atoms in a magneto-optical trap and a
Bose-Einstein condensate (BEC) is experimentally investigated. Using 100 ns
laser pulses, we detect single ions photoionized from the condenstate with a
35(10)% efficiency. The measurements are performed using a quartz cell with
external electrodes, allowing large optical access for BECs and optical
lattices.Comment: 14 pages, 7 figure
Lifetime determination of excited states in Cd-106
Two separate experiments using the Differential Decay Curve Method have been performed to extract mean lifetimes of excited states in 106 Cd. The inedium-spin states of interest were populated by the Mo-98(C-12, 4n) Cd-106 reaction performed at the Wright Nuclear Structure Lab., Yale University. From this experiment, two isomeric state mean lifetimes have been deduced. The low-lying states were populated by the Mo-96(C-13, 3n)Cd-106 reaction performed at the Institut fur Kernphysik, Universitat zu Koln. The mean lifetime of the I-pi = 2(1)(+) state was deduced, tentatively, as 16.4(9) ps. This value differs from the previously accepted literature value from Coulomb excitation of 10.43(9) ps
Structural basis for c-di-AMPâdependent regulation of the bacterial stringent response by receptor protein DarB
The bacterial second messenger c-di-AMP controls essential cellular processes, including potassium and osmolyte homeostasis. This makes synthesizing enzymes and components involved in c-di-AMP signal transduction intriguing as potential targets for drug development. The c-di-AMP receptor protein DarB of Bacillus subtilis binds the Rel protein and triggers the Rel-dependent stringent response to stress conditions; however, the structural basis for this trigger is unclear. Here, we report crystal structures of DarB in the ligand-free state and of DarB complexed with c-di-AMP, 3âČ3âČ-cGAMP, and AMP. We show that DarB forms a homodimer with a parallel, head-to-head assembly of the monomers. We also confirm the DarB dimer binds two cyclic dinucleotide molecules or two AMP molecules; only one adenine of bound c-di-AMP is specifically recognized by DarB, while the second protrudes out of the donut-shaped protein. This enables DarB to bind also 3âČ3âČ-cGAMP, as only the adenine fits in the active site. In absence of c-di-AMP, DarB binds to Rel and stimulates (p)ppGpp synthesis, whereas the presence of c-di-AMP abolishes this interaction. Furthermore, the DarB crystal structures reveal no conformational changes upon c-di-AMP binding, leading us to conclude the regulatory function of DarB on Rel must be controlled directly by the bound c-di-AMP. We thus derived a structural model of the DarBâRel complex via in silico docking, which was validated with mass spectrometric analysis of the chemically crosslinked DarBâRel complex and mutagenesis studies. We suggest, based on the predicted complex structure, a mechanism of stringent response regulation by c-di-AMP
Efficient generation of 380 fs pulses of THz radiation by ultrafast laser pulse excitation of a biased metal-semiconductor interface
We have demonstrated a new method of generating pulses of freely propagating THz electromagnetic radiation. The resulting 380 fs pulses are the shortest directly measured THz pulses in free space to date and are more powerful than those generated by Hertzian dipoles or by resonant dipole antennas. Temporal features as short as 190 fs were observed on these THz radiation pulses and thereby, illustrate an ultrafast receiver response time.Peer reviewedElectrical and Computer Engineerin
A Rydberg Quantum Simulator
Following Feynman and as elaborated on by Lloyd, a universal quantum
simulator (QS) is a controlled quantum device which reproduces the dynamics of
any other many particle quantum system with short range interactions. This
dynamics can refer to both coherent Hamiltonian and dissipative open system
evolution. We investigate how laser excited Rydberg atoms in large spacing
optical or magnetic lattices can provide an efficient implementation of a
universal QS for spin models involving (high order) n-body interactions. This
includes the simulation of Hamiltonians of exotic spin models involving
n-particle constraints such as the Kitaev toric code, color code, and lattice
gauge theories with spin liquid phases. In addition, it provides the
ingredients for dissipative preparation of entangled states based on
engineering n-particle reservoir couplings. The key basic building blocks of
our architecture are efficient and high-fidelity n-qubit entangling gates via
auxiliary Rydberg atoms, including a possible dissipative time step via optical
pumping. This allows to mimic the time evolution of the system by a sequence of
fast, parallel and high-fidelity n-particle coherent and dissipative Rydberg
gates.Comment: 8 pages, 4 figure
The physics of dipolar bosonic quantum gases
This article reviews the recent theoretical and experimental advances in the
study of ultracold gases made of bosonic particles interacting via the
long-range, anisotropic dipole-dipole interaction, in addition to the
short-range and isotropic contact interaction usually at work in ultracold
gases. The specific properties emerging from the dipolar interaction are
emphasized, from the mean-field regime valid for dilute Bose-Einstein
condensates, to the strongly correlated regimes reached for dipolar bosons in
optical lattices.Comment: Review article, 71 pages, 35 figures, 350 references. Submitted to
Reports on Progress in Physic
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