Hybridization: Expressing yourself in a crowd

SummaryWhat happens to the expression of homeologous gene copies during the formation of new allopolyploid hybrids and their subsequent evolution? Recent studies have shown that hybridisation may relax transcriptional regulation and enable subsequent allopolyploid generations to develop novel patterns of parental gene expression

Academic Service-Learning: Current Findings and Future Directions

This paper seeks to provide university administrators and faculty who may be considering the implementation of Academic Service Learning (ASL) with a comprehensive 360 degree viewpoint so as to aid in the decision making of whether ASL may be appropriate as a learning tool for their particular college or university. The article does this by exploring the research literature on Academic Service Learning (ASL) and identifies the prevalent streams of current research. The initial stream deals with the reasons and evolution for the creation of academic service-learning. Further streams of research identify factors that make academic programs a success, reveals the benefits students and community organizations derive from service-learning as well as the drawbacks of service-learning. In discussing each stream examples are provided on how colleges have used ASL. A preponderance of methodological deficiencies are identified in terms the current research and recommendations for improvement are proposed with the utilization of better quasi experiments that will reduce the number of threats to internal as well as the external validity. Eight research proposals are stated to guide future academic service-learning research

Academic Service Learning and Society: From Individual to Institutional

This paper examines how Academic Service Learning (ASL) has gone from being an initiative by individual faculty to being institutionalized by universities as means to promote learning, pursue mission, and impact society. It outlines various uses of ASL by individual faculty and examines its progression into a university sponsored service-learning vessel of vision and mission. Its use acknowledges the interconnectedness of universities and society and emphasizes the need and obligation that universities feel, or should feel, in contributing to the betterment of the world we live in. In terms of being a university-sponsored initiative it highlights its use in the business curriculum of a large university in the northeast United States. This article recommends that ASL is an easily instituted method of teaching in many disciplines and is of benefit to multiple constituents both internally and externally to academic institutions

Network coherence in autism spectrum disorder : a multimodal neuroimaging study of functional connectivity and spectroscopy MRI

The underlying neuropathology and effects on neuronal activity in individuals with ASD are still being elucidated; as well as their impact on intervention and treatment outcomes. Frontal, temporal, parietal and cerebellar pathways exhibit disrupted structural and functional connectivity in individuals with ASD and we sought to investigate the potential clinical utility of altered network coherence. Beta-adrenergic antagonism improved information processing in a subset of individuals with ASD and improved performance was related to pharmacologicallymediated alterations in functional connectivity in the fronto-parietal control network. These findings support the potential utility of beta-adrenergic antagonists for some patients with ASD and the clinical significance of alterations in network coherence. There are also additional considerations for functional connectivity investigations in ASD. The cerebellum is interconnected via feedback loops to the neocortex and thus has some modulatory influences on cortical and subcortical neuronal circuits. The cerebellum is consistently implicated in the neuropathology of ASD but has been largely ignored in investigations of functional network coherence. Functional connectivity between the cerebellum and neocortex was anticorrelated in a subset of individuals with ASD. These individuals exhibited reduced glutamate levels in the cerebellum and diminished interpretive linguistic abilities, suggesting a potential mechanism underlying altered cerebrocerebellar connectivity in some individuals with ASD as well a cognitive outcome of alterations in cerebrocerebellar network coherence

Leveraging lessons learned in organizations through implementing practice-based organizational learning and performance improvement - An opportunity for context-based intelligent assistant support (CIAS)

Organizations that leverage lessons learned from their experience in the practice of complex real-world activities are faced with five difficult problems. First, how to represent the learning situation in a recognizable way. Second, how to represent what was actually done in terms of repeatable actions. Third, how to assess performance taking account of the particular circumstances. Fourth, how to abstract lessons learned that are re-usable on future occasions. Fifth, how to determine whether to pursue practice maturity or strategic relevance of activities. Here, organizational learning and performance improvement are investigated in a field study using the Context-based Intelligent Assistant Support (CIAS) approach. A new conceptual framework for practice-based organizational learning and performance improvement is presented that supports researchers and practitioners address the problems evoked and contributes to a practice-based approach to activity management. The novelty of the research lies in the simultaneous study of the different levels involved in the activity. Route selection in light rail infrastructure projects involves practices at both the strategic and operational levels; it is part managerial/political and part engineering. Aspectual comparison of practices represented in Contextual Graphs constitutes a new approach to the selection of Key Performance Indicators (KPIs). This approach is free from causality assumptions and forms the basis of a new approach to practice-based organizational learning and performance improvement. The evolution of practices in contextual graphs is shown to be an objective and measurable expression of organizational learning. This diachronic representation is interpreted using a practice-based organizational learning novelty typology. This dissertation shows how lessons learned when effectively leveraged by an organization lead to practice maturity. The practice maturity level of an activity in combination with an assessment of an activity’s strategic relevance can be used by management to prioritize improvement effort