Fall-Related Stigma in Older Adulthood: A Mixed Methods Approach to Understanding the Influence of Stigma on Older Adults\u27 Reported Attitudes and Behaviours Regarding Falls

Falls during older adulthood present a major threat to the health and wellbeing of older adults and a challenge to society. While effective fall prevention strategies have been developed to address risk factors for falls, older adults commonly resist participation in such programming and dissociate from the topic of falls in general. After reviewing research findings and the theoretical literature, support was found for approaching falls as a stigmatizing topic for older adults. Three mixed methods experiments were completed to test the influence of stigma on older adults‟ attitudes, opinions, and behaviours. Experiments 1 and 2 tested the labelling aspect of fall-related stigma on older adults‟ attitudes and reported behaviours. Experiment 1 randomly assigned participants to receive an exercise program described as either an “exercise class for older adults” or a “fall prevention exercise class for older adults”. Experiment 2 modified the study design of Experiment 1 and presented each participant with a two-alternative, forced-choice response between the two exercise program descriptions. When given the opportunity to participate in either the non-labelled exercise class or the labelled, fall prevention exercise class, the majority of participants (79%) preferred the non-labelled exercise program option. However, a subgroup of older adults identified with the fall prevention label, selected it as their preferred program, and provided a logical rationale for doing so. Analyses were conducted to investigate whether other survey responses could be used to better understand participants‟ choices. The key factors related to participants‟ perceptions of falls and stigma were identified by the predictors uncovered. Experiment 3 then used the factors from Experiment 2 to determine whether an informational message addressing the key constructs could mitigate the negative fall prevention label. After reading a randomly assigned vignette addressing the key statements, participants were asked to make a two-alternative, forced-choice response for their preferred exercise program. The results indicated that the informational vignette was effective in de-stigmatizing the fall prevention label, with 41% of respondents selecting it as their preferred program. The findings of these experiments indicate that while falls are a stigmatizing topic for older adults, it appears to be amenable to attenuation

Experiences of a Novice Researcher Conducting Focus Group Interviews

The purpose of this paper is to report what I learned about how to conduct focus group interviews that produce insightful, revealing and informative data.  I will discuss my experiences facilitating focus group interviews as a novice researcher and compare these experiences with the literature.  I planned the focus groups in collaboration with a research team, recruited participants from various units at the local tertiary care hospital and set up the meeting rooms for the groups.  I then facilitated the focus groups with the support of an assistant.  Following the focus groups, I documented my field notes, as well as my personal reflective memos.  I downloaded the audio recordings, de-identified the written transcripts, and reviewed them for accuracy prior to analysis.  A number of concepts emerged that merit particular attention: challenges with recruitment, the use of field notes and reflective memos, the benefits and limitations of using a flip chart, importance of professional support, using homogenous groups, and attending to the set-up of the environment.  As the focus group interview becomes an increasingly popular data collection method in qualitative research, my experiences could inform the preparation of other novice researchers as they undertake their own focus groups

2,5-Dimethyl-1,3-dinitro­benzene

The title compound, C8H8N2O4, was prepared via the nitration of p-xylene. The mol­ecules are stacked along the c axis in an antiparallel manner. The two nitro groups are rotated relative to the benzene ring with dihedral angles of 44.50 (7) and 31.67 (8)°. The tilt of the nitro groups allows the formation of C—H⋯O inter­actions between the ring C—H and nitro groups of adjacent mol­ecules creating puckered sheets perpendicular to the c axis. The H atoms of the methyl group in the 5-position are disordered (60° rotation) with an occupancy of 0.616 (19) for the major component. The crystal was found to be a non-merohedral twin with a twin law [−1 −0.002 0.005, 0.00031 −1 0.002, 0.118 −0.007 1] corresponding to a rotation of 180° about the reciprocal axis (001) and refined to give a minor component fraction of 0.320 (2)

Characteristics and Predictive Value of Blood Transcriptome Signature in Males with Autism Spectrum Disorders

Autism Spectrum Disorders (ASD) is a spectrum of highly heritable neurodevelopmental disorders in which known mutations contribute to disease risk in 20% of cases. Here, we report the results of the largest blood transcriptome study to date that aims to identify differences in 170 ASD cases and 115 age/sex-matched controls and to evaluate the utility of gene expression profiling as a tool to aid in the diagnosis of ASD. The differentially expressed genes were enriched for the neurotrophin signaling, long-term potentiation/depression, and notch signaling pathways. We developed a 55-gene prediction model, using a cross-validation strategy, on a sample cohort of 66 male ASD cases and 33 age-matched male controls (P1). Subsequently, 104 ASD cases and 82 controls were recruited and used as a validation set (P2). This 55-gene expression signature achieved 68% classification accuracy with the validation cohort (area under the receiver operating characteristic curve (AUC): 0.70 [95% confidence interval [CI]: 0.62–0.77]). Not surprisingly, our prediction model that was built and trained with male samples performed well for males (AUC 0.73, 95% CI 0.65–0.82), but not for female samples (AUC 0.51, 95% CI 0.36–0.67). The 55-gene signature also performed robustly when the prediction model was trained with P2 male samples to classify P1 samples (AUC 0.69, 95% CI 0.58–0.80). Our result suggests that the use of blood expression profiling for ASD detection may be feasible. Further study is required to determine the age at which such a test should be deployed, and what genetic characteristics of ASD can be identified

Additional Massive Binaries in the Cygnus OB2 Association

We report the discovery and orbital solutions for two new OB binaries in the Cygnus OB2 Association, MT311 (B2V+B3V) and MT605 (B0.5V+B2.5:V). We also identify the system MT429 as a probable triple system consisting of a tight eclipsing 2.97 day B3V+B6V pair and a B0V at a projected separation of 138 AU. We further provide the first spectroscopic orbital solutions to the eclipsing, double-lined, O-star binary MT696 (O9.5V+B1:V), the double-lined, early B binary MT720 (B0-1V+B1-2V), and the double-lined, O-star binary MT771 (O7V+O9V). These systems exhibit orbital periods between 1.5 days and 12.3 days, with the majority having P<6 days. The two new binary discoveries and six spectroscopic solutions bring the total number of known massive binaries in the central region of the Cygnus OB2 Association to 20, with all but two having full orbital solutions.Comment: 42 pages, 16 figures, accepted for publication in the Astrophysical Journal, minor typos have been fixe

Comprehensive ecosystem model-data synthesis using multiple data sets at two temperate forest free-air CO2 enrichment experiments: Model performance at ambient CO2 concentration

Free-air CO2 enrichment (FACE) experiments provide a remarkable wealth of data which can be used to evaluate and improve terrestrial ecosystem models (TEMs). In the FACE model-data synthesis project, 11 TEMs were applied to two decadelong FACE experiments in temperate forests of the southeastern U.S.—the evergreen Duke Forest and the deciduous Oak Ridge Forest. In this baseline paper, we demonstrate our approach to model-data synthesis by evaluating the models' ability to reproduce observed net primary productivity (NPP), transpiration, and leaf area index (LAI) in ambient CO2 treatments. Model outputs were compared against observations using a range of goodness-of-fit statistics. Many models simulated annual NPP and transpiration within observed uncertainty. We demonstrate, however, that high goodness-of-fit values do not necessarily indicate a successful model, because simulation accuracy may be achieved through compensating biases in component variables. For example, transpiration accuracy was sometimes achieved with compensating biases in leaf area index and transpiration per unit leaf area. Our approach to model-data synthesis therefore goes beyond goodness-of-fit to investigate the success of alternative representations of component processes. Here we demonstrate this approach by comparing competing model hypotheses determining peak LAI. Of three alternative hypotheses—(1) optimization to maximize carbon export, (2) increasing specific leaf area with canopy depth, and (3) the pipe model—the pipe model produced peak LAI closest to the observations. This example illustrates how data sets from intensive field experiments such as FACE can be used to reduce model uncertainty despite compensating biases by evaluating individual model assumptions

Global health education: a pilot in trans-disciplinary, digital instruction

Background: The development of new global health academic programs provides unique opportunities to create innovative educational approaches within and across universities. Recent evidence suggests that digital media technologies may provide feasible and cost-effective alternatives to traditional classroom instruction; yet, many emerging global health academic programs lag behind in the utilization of modern technologies. Objective: We created an inter-departmental University of Southern California (USC) collaboration to develop and implement a course focused on digital media and global health. Design: Course curriculum was based on core tenants of modern education: multi-disciplinary, technologically advanced, learner-centered, and professional application of knowledge. Student and university evaluations were reviewed to qualitatively assess course satisfaction and educational outcomes. Results: &#x2018;New Media for Global Health&#x2019; ran for 18 weeks in the Spring 2012 semester with N=41 students (56.1% global health and 43.9% digital studies students). The course resulted in a number of high quality global health-related digital media products available at http://iml420.wordpress.com/. Challenges confronted at USC included administrative challenges related to co-teaching and frustration from students conditioned to a rigid system of teacher-led learning within a specific discipline. Quantitative and qualitative course evaluations reflected positive feedback for the course instructors and mixed reviews for the organization of the course. Conclusion: The development of innovative educational programs in global health requires on-going experimentation and information sharing across departments and universities. Digital media technologies may have implications for future efforts to improve global health education

Expressions 2001

https://openspace.dmacc.edu/expressions/1020/thumbnail.jp