IMPLEMENTASI BELLMAN-FORD DAN FLOYD-WARSHALL DALAM MENENTUKAN JALUR TERPENDEK MENUJU UNIVERSITAS NASIONAL BERBASIS ANDROID

Disekitar Universitas Nasional memiliki berbagai macam jenis transportasi umum. Sebagian besar masyarakat dan mahasiswa Universitas Nasional masih menggunakan transportasi umum seperti kereta api dan transjakarta, namun masih terkendala jarak antara stasiun dan halte ke Universitas Nasional. Penelitian ini menerapkan algoritma Bellman-Ford dan Floyd-Warshall yang dinilai efektif dan telah banyak digunakan pada penelitian sebelumnya dalam pencarian jalur terpendek diantaranya yaitu pengantaran barang, pencarian kampus dan pencarian lokasi travel. Penelitian ini bertujuan untuk mempermudah masyarakat, khususnya mahasiswa atau peserta didik baru dalam mencari jalur terdekat dari stasiun dan halte menuju Universitas Nasional. Penelitian ini dirancang menggunakan framework flutter dan bahasa pemrograman dart berbasis android dengan pengguna terbanyak pada saat ini. Berdasarkan hasil pengujian, algoritma Bellman-Ford dan Floyd-Warshall untuk kasus pencarian jarak terpendek dari stasiun Pasar Minggu diperoleh jarak terpendek sebesar 1.54 km dengan tingkat keefektifan jarak sebesar 39.40%, sedangkan kasus pencarian jarak terpendek dari halte Jatipadang diperoleh jarak terpendek sebesar 1.97 km dengan tingkat keefektifan jarak sebesar 25.24%

FORMULA OPTIMIZATION OF PLANTAGO (PLANTAGO MAJOR L.) HERB EXTRACT CHEWABLE TABLETS AT VARIOUS MANITOL- LACTOSE RATIO USING SIMPLEX LATTICE DESIGN

The use of plantago (Plantago major L.) traditionally is less practical, therefore it needs to be developed into chewable tablet dosage form which is more acceptable. To prepare chewable tablet, lactose as a fi ller was used to substitute a part of mannitol which is relatively more expensive. Simplex lattice design (SLD) method was used to obtain the optimum ratio of mannitol-lactose mixture. Formula optimization using SLD was determined by testing of the granules physical properties: fl ow properties, compactibilities, and absorption capacities of water at various ratio. Plantago herbs were extracted by decoction and characterized. Granules of optimum formula were compressed into tablets and followed by testing its qualities: weight uniformities, hardness, brittleness, and qualitative analysis of chemical compounds using thin layer chromatography. Physical properties data of granules and chewable tablets were analysed using theoretical method and statistical with T test. The results showed that the increase of lactose proportion increased the fl ow properties, compactibilities, and absorption capacities of water. T-test at 95% confi dence level (α=0.05) indicated that SLD equalization was valid. Optimum area located between lactose-mannitol 100% : 0% and 20% : 80% with optimum formula was lactose-mannitol 100% : 0% as an optimum formula

Enzim Selulase Kasar Aspergillus niger FNCC 6018 untuk Produksi Bioetanol melalui Proses Sakarifikasi dan Fermentasi Serentak

Penelitian ini bertujuan mendapatkan kondisi pertumbuhan optimum pH, suhu, dan waktu inkubasi dari Aspergillus niger FNCC 6018 untuk produksi enzim selulase kasar dengan aktivitas spesifik maksimum pada substrat bagas tebu. Aktivitas spesifik maksimum A. niger FNCC 6018 dioptimasi dengan perlakuan variasi pH 5, 6, 7; suhu 27, 37, 50°C dan waktu inkubasi 5, 7, 9 hari. Kondisi optimum yang diperoleh digunakan untuk memproduksi enzim selulase kasar dan selanjutnya digunakan dalam proses produksi bioetanol. Produksi bioetanol dilakukan dengan metode Simultaneous Saccharification and Fermentation (SSF) pada suhu ruang, pH 5, selama 5 hari menggunakan substrat bagas tebu, enzim selulase kasar A. niger FNCC 6018, khamir Saccharomyces cerevisiae FNCC 3012, dan medium SSF. Pada akhir tahap SSF, kadar glukosa diukur dengan metode DNS (Dinitro Salisilat) sedangkan kadar etanol diukur dengan metode Gas Chromatography.Hasil penelitian menunjukkan bahwa kondisi optimum untuk produksi enzim selulase kasar A. niger FNCC 6018 berada pada pH 5, suhu 37oC, waktu inkubasi 9 hari dengan aktivitas spesifik selulase kasar sebesar 0.107 U/mg. Kadar glukosa dan etanol maksimal dengan metode SSF adalah 0.59 mg/mL dan 1.217%. Metode ini cukup potensial untuk produksi bioetanol dari bagas tebu

PENGARUH MOTIVASI KERJA DAN PENGALAMAN KERJA PADA KOMITMEN PEDOMAN CARA PEMBUATAN OBAT YANG BAIK (CPOB) (STUDI KASUS DI PT. BERLICO MULIA FARMA)

The Indonesian government has issued Good Manufacturing Practices (GMP) policy for implementation in the pharmaceutical industry since 1988. GMP concept is very dynamic due to adjustments following the progress of pharmaceutical technology. The successful implementation of GMP requires employee�s commitment. The main aim of this thesis is to study the influences of: (1) work motivation and (2) job experiences on employee�s commitment to the Good Manufacturing Practices (GMP). The study approach is a quantitative explanation. The population was 164 permanent employees of Berlico Mulia Farma Company (BMF Ltd.) which working in production department, quality control department, research and development department, production planning and inventory control department, and quality assurance department. The samples were 27% of the total population, i.e. 45. Samples were selected by stratified random sampling technique based on their position. Data were collected by questionnaires. The validity test of instruments obtained with Pearson correlation. The reliability of instrument based on Alpha Cronbach coefficients is good (between 0.786 to 0.867). Data analysis performed using single and multiple regression. Single regression analysis indicate that: (1) there is a significant effect (t = 2.199, p <0.05) of work motivation on commitment to the GMP and (2) there is a significant effect (t = 4.869, p <0.05) of job experiences on commitment to the GMP. The result of multiple regression analysis show that there is a significant effect (F = 64.489, p <0.05) of work motivation and job experiences on commitment to the GMP simultaneously

DYEING OF COTTON FABRIC WITH NATURAL DYE FROM CUDRANIA JAVANENSIS USING SOKA LEAVES EXTRACT AS BIOMORDANT

Tegeran wood (Cudrania javanensis) has been used for dyeing process of batik in Indonesian textile small medium scale enterprise. This wood gave soga color when it was mixed with others natural dye. This study was aim to evaluate the caharacteristic, fastness properties, and strength color of dyed cotton fabrics using C. javanensis with bio-mordant soka leaves extract. Extraction of C. javanensis was carried out using water. The post mordant process was carried out by applying alum (KAl(SO4)2•12H2O) solution and soka leaves extract on cotton fabrics with the concentration of 0.5 and 1% b/v. Characteristic of dyed cotton fabrics then was evaluated using Fourier-Transform Infrared (F-TIR) Spectroscopy. The results exhibited that, binding between tegeran wood on cotton using mordant alum and soka leaves extract was similar.The fastness properties both dyed cottons toward light and  washing at 40ºC exhibited poor and very poor values with values of 1-2 and 1. The dry and wet rubbing of dyed cotton using soka leaves extract mordant better than using alum. The soka leaves extract gave yellow and brightness color on cotton.The results suggested that soka leaves extract can be used as mordant substitute the alum mordant and apllied with others natural dyes