Asymptotic behaviour of neuron population models structured by elapsed-time

We study two population models describing the dynamics of interacting neurons, initially proposed by Pakdaman et al (2010 Nonlinearity 23 55–75) and Pakdaman et al (2014 J. Math. Neurosci. 4 1–26). In the first model, the structuring variable s represents the time elapsed since its last discharge, while in the second one neurons exhibit a fatigue property and the structuring variable is a generic 'state'. We prove existence of solutions and steady states in the space of finite, nonnegative measures. Furthermore, we show that solutions converge to the equilibrium exponentially in time in the case of weak nonlinearity (i.e. weak connectivity). The main innovation is the use of Doeblin's theorem from probability in order to show the existence of a spectral gap property in the linear (no-connectivity) setting. Relaxation to the steady state for the nonlinear models is then proved by a constructive perturbation argument.MTM2014-52056-P, MTM2017-85067-P, "la Caixa" Foundatio

Influence of different light-curing units on monomer elution from bulk fill composites

Hatipoglu, Omer/0000-0002-4628-8551; Karadas, Muhammet/0000-0002-3357-6896WOS: 000456292100008Objectives: This in vitro study assessed the effect of different light-curing units on the elution of monomers from bulk fill composites with different thicknesses. Methods: Five bulk fill composites (Filtek Bulk Fill Flowable, SonicFill 2, SDR, Tetric N-Ceram Bulk Fill, and Venus Bulk Fill) and one conventional composite (Filtek Z250) were selected for the study. the cylindrical specimens in thickness of 2 mm or 4 mm were prepared and photopolymerized for 20 s with a light-emitting diode (VALO Cordless) or a halogen (Monitex BlueLuxer) light-curing unit. the specimens in glass vials were covered with a 75% ethanol/water solution. Ethanol/water extraction solutions were collected for high-performance liquid chromatography analysis after 24 h, 3 days, and 7 days. the data were analyzed with repeated measures and three-way ANOVA (p < 0.05). Results: the total monomer amount was significantly influenced by light-curing source used and thickness. the highest levels of Bis-GMA and Bis-EMA were eluted from Tetric N-Ceram BulkFill and Venus Bulk Fill, respectively. SonicFill 2 released the highest level of TEGDMA at 4-mm thickness. the highest levels of UDMA release, from 4-mm-thick Filtek Bulk Fill Flowable, were attained using the halogen unit. Conclusions: Light-curing sources affected the number of monomers released by materials. the amount of eluted monomers declined over time. the increased ratio of released monomers to increased thickness is material dependent. the number of residual monomers is highly associated with the resin ratio and crosslinking network of the composites.Recep Tayyip Erdogan University Research FundRecep Tayyip Erdogan University [2015.53001.111.03.01]1 This study was supported by Recep Tayyip Erdogan University Research Fund under Grant (Project code: [2015.53001.111.03.01])

Is intraarticular sodium hyaluronate injection an alternative treatment in patients with adhesive capsulitis?

The aim of this study was to compare the efficacy of sodium hyaluronate (SH) injection with the most common treatment methods, intraarticular steroid injection and physical therapy modalities in patients with adhesive capsulitis (AC). A total of 95 shoulders of 90 patients were included in the study and were randomized in four groups. The patients were treated with SH injection (group 1), triamsinolone acetonide (group 2) or physical therapy modalities (group 3). Group 4 patients were served as controls. Pain severity, passive ranges of motion and functional considerations were measured before, and 15 days and 3 months after the treatments. In all treatment groups, there were significant improvements at both the 15th day and third month in all parameters (for each, p < 0.001). The passive abduction values on the 15th day was found significantly higher in group 3 when compared with group 1 and controls (for each, p < 0.001). At the third month, the passive abduction values of the groups 2 and 3 were improved when compared with the control group (p < 0.001). Constant score was higher in group 3 on 15th day when compared with group 1. At the third month, all treatment groups were improved significantly compared with control group (p < 0.001). We provided the best results in physical therapy modalities applied group for AC treatment. However, we think that SH injection may be administered as an alternative treatment method

Українська версія опитувальника оцінки сімптомів гострого циститу (Acute cystitis symptom score – ACSS) для діагностики та результатів гострого неускладненого циститу, про які повідомляють пацієнтки. Ч. I. Лінгвістична валідація та когнітивна оцінка

The Acute Cystitis Symptom Score (ACSS) was originally developed in Uzbek and Russian language as a self-reporting questionnaire for the clinical diagnosis and follow-up of an acute episode of uncomplicated cystitis (AC) in women based on complains and their effect on the quality of life. After professional forward and backward translations the cognitive assessment of the Ukrainian version of the ACSS was performed in female subjects with different ages and educational levels and in medical professionals treating such patients. After considering all comments of the female subjects and the professionals the final version of the Ukrainian ACSS could be obtained to be further used in clinical studies.Опитувальник оцінки симптомів гострого циститу (ACSS) – це анкета для самозвіту для клінічної діагностики гострого циститу (ГЦ) на основі скарг. Він поєднує поетапну оцінку тяжкості симптомів та їх впливу на якість життя. ACSS складається з двох частин: діагностичної (частина А) та контрольної (частина Б) форм. Обидві частини включають чотири ідентичні домени, що містять: а) шість пунктів для "типових" симптомів ГЦ; б) чотири пункти для диференціальної діагностики; в) три пункти для якості життя та г) п'ять пунктів для додаткових станів. Частина В містить додатково ще один домен, який називається "Динаміка", спрямований на моніторинг змін стану пацієнта під час спостереження