56 research outputs found

    An epidemiological approach to simulation-based analysis of large building stocks

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    This paper describes a novel approach to building stock energy modelling: Individual building simulation models are autogenerated for each building in the stock, and the resulting set of virtual buildings is selectively sampled, simulated and analysed in much the same way that an epidemiologist might study a population through surveys and statistical analysis. A conceptual and software framework is described, along with initial case study results for a London borough

    Comparison of Chiller Models for Use in Model-Based Fault Detection

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    Selecting the model is an important and essential step in model based fault detection and diagnosis (FDD). Factors that are considered in evaluating a model include accuracy, training data requirements, calibration effort, generality, and computational requirements. The objective of this study was to evaluate different modeling approaches for their applicability to model based FDD of vapor compression chillers. Three different models were studied: the Gordon and Ng Universal Chiller model (2nd generation) and a modified version of the ASHRAE Primary Toolkit model, which are both based on first principles, and the DOE-2 chiller model, as implemented in CoolToolsTM, which is empirical. The models were compared in terms of their ability to reproduce the observed performance of an older, centrifugal chiller operating in a commercial office building and a newer centrifugal chiller in a laboratory. All three models displayed similar levels of accuracy. Of the first principles models, the Gordon-Ng model has the advantage of being linear in the parameters, which allows more robust parameter estimation methods to be used and facilitates estimation of the uncertainty in the parameter values. The ASHRAE Toolkit Model may have advantages when refrigerant temperature measurements are also available. The DOE-2 model can be expected to have advantages when very limited data are available to calibrate the model, as long as one of the previously identified models in the CoolTools library matches the performance of the chiller in question

    Demand Relief and Weather Sensitivity in Large California Commercial Office Buildings

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    A great deal of research has examined the weather sensitivity of energy consumption in commercial buildings; however, the recent power crisis in California has given greater importance to peak demand. Several new loadshedding programs have been implemented or are under consideration. Historically, the target customers have been large industrial users who can reduce the equivalent load of several large office buildings. While the individual load reduction from an individual office building may be less significant, there is ample opportunity for load reduction in this area. The load reduction programs and incentives for industrial customers may not be suitable for commercial building owners. In particular, industrial customers are likely to have little variation in load from day to day. Thus a robust baseline accounting for weather variability is required to provide building owners with realistic targets that will encourage them to participate in load shedding programs

    Comments on Non-Commutative Phenomenology

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    It is natural to ask whether non-commutative geometry plays a role in four dimensional physics. By performing explicit computations in various toy models, we show that quantum effects lead to violations of Lorentz invariance at the level of operators of dimension three or four. The resulting constraints are very stringent.Comment: Correction of an error in the U(1) and U(N) calculation leads to stronger limits than those given previously Clarifying comments and reference adde

    Weak-Lensing by Large-Scale Structure and the Polarization Properties of Distant Radio-Sources

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    We estimate the effects of weak lensing by large-scale density inhomogeneities and long-wavelength gravitational waves upon the polarization properties of electromagnetic radiation as it propagates from cosmologically distant sources. Scalar (density) fluctuations do not rotate neither the plane of polarization of the electromagnetic radiation nor the source image. They produce, however, an appreciable shear, which distorts the image shape, leading to an apparent rotation of the image orientation relative to its plane of polarization. In sources with large ellipticity the apparent rotation is rather small, of the order (in radians) of the dimensionless shear. The effect is larger at smaller source eccentricity. A shear of 1% can induce apparent rotations of around 5 degrees in radio sources with the smallest eccentricity among those with a significant degree of integrated linear polarization. We discuss the possibility that weak lensing by shear with rms value around or below 5% may be the cause for the dispersion in the direction of integrated linear polarization of cosmologically distant radio sources away from the perpendicular to their major axis, as expected from models for their magnetic fields. A rms shear larger than 5% would be incompatible with the observed correlation between polarization properties and source orientation in distant radio galaxies and quasars. Gravity waves do rotate both the plane of polarization as well as the source image. Their weak lensing effects, however, are negligible.Comment: 23 pages, 2 eps figures, Aastex 4.0 macros. Final version, as accepted by ApJ. Additional references and some changes in the introduction and conclusion

    Brain inflammation is accompanied by peripheral inflammation in Cstb(-/-) mice, a model for progressive myoclonus epilepsy

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    Progressive myoclonus epilepsy of Unverricht-Lundborg type (EPM1) is an autosomal recessively inherited childhood-onset neurodegenerative disorder, characterized by myoclonus, seizures, and ataxia. Mutations in the cystatin B gene (CSTB) underlie EPM1. The CSTB-deficient (Cstb(-/-)) mouse model recapitulates key features of EPM1, including myoclonic seizures. The mice show early microglial activation that precedes seizure onset and neuronal loss and leads to neuroinflammation. We here characterized the inflammatory phenotype of Cstb(-/-) mice in more detail. We found higher concentrations of chemokines and pro-inflammatory cytokines in the serum of Cstb(-/-) mice and higher CXCL13 expression in activated microglia in Cstb(-/-) compared to control mouse brains. The elevated chemokine levels were not accompanied by blood-brain barrier disruption, despite increased brain vascularization. Macrophages in the spleen and brain of Cstb(-/-) mice were predominantly pro-inflammatory. Taken together, these data show that CXCL13 expression is a hallmark of microglial activation in Cstb(-/-)mice and that the brain inflammation is linked to peripheral inflammatory changes, which might contribute to the disease pathology of EPM1.Peer reviewe

    Connecting the sustainable development goals by their energy inter-linkages

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    The United Nations' Sustainable Development Goals (SDGs) provide guide-posts to society as it attempts to respond to an array of pressing challenges. One of these challenges is energy; thus, the SDGs have become paramount for energy policy-making. Yet, while governments throughout the world have already declared the SDGs to be 'integrated and indivisible', there are still knowledge gaps surrounding how the interactions between the energy SDG targets and those of the non-energy-focused SDGs might play out in different contexts. In this review, we report on a large-scale assessment of the relevant energy literature, which we conducted to better our understanding of key energy-related interactions between SDGs, as well as their context-dependencies (relating to time, geography, governance, technology, and directionality). By (i) evaluating the nature and strength of the interactions identified, (ii) indicating the robustness of the evidence base, the agreement of that evidence, and our confidence in it, and (iii) highlighting critical areas where better understanding is needed or context dependencies should be considered, our review points to potential ways forward for both the policy making and scientific communities. First, we find that positive interactions between the SDGs outweigh the negative ones, both in number and magnitude. Second, of relevance for the scientific community, in order to fill knowledge gaps in critical areas, there is an urgent need for interdisciplinary research geared toward developing new data, scientific tools, and fresh perspectives. Third, of relevance for policy-making, wider efforts to promote policy coherence and integrated assessments are required to address potential policy spillovers across sectors, sustainability domains, and geographic and temporal boundaries. The task of conducting comprehensive science-to-policy assessments covering all SDGs, such as for the UN's Global Sustainable Development Report, remains manageable pending the availability of systematic reviews focusing on a limited number of SDG dimensions in each case
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