To Find the Best Site for Urban Development in Prachuap Khiri khan, Thailand

Coastal areas in the western provinces of Thailand, a popular destination in Northern Thailand, are facing rapid tourism-related sustainable development issues and. This study aims to find the coastal areas which need to be conserved for tourism and find the areas which are safer and suitable for urban development in Prachuap Khirikhan province. Multiple criteria evaluation (MCE) and several available tools in GIS such as ‘Reclassify’, ‘Overlay’, ‘Proximity’, ‘Spatial analyst tools’ etc. are used during analysis. ‌Based on the available data and multi-criteria analysis, the area in the Prachuap Khirikhan has been classified into five categories from “Highly Suitable” to “Not Suitable. The results show that there are large number of Tambon which are highly suitable for urban development such as Phung Prasan, Kamnoet Nopphakhun, Thong chai, Thap sake, Huai Yang, Huai sai, Khlong Wan, Ko Lak, Ao Noi, Bo Nok. The Tambons which are found “Not suitable” or “Low suitable” for urban development are Nong Phap, Nong Ta Taem, Sila Loi and Chang Raek

Incentives in Adopting Cloud Computing for Shaikh Zayed University, Khost Afghanistan

Teaching in these days is almost regarded impossible without the Information Technology resources which needs a great amount of investments in this sector, there are a huge number of educational institutions which cannot afford these IT investments. Many institutions are in search of a cheap and economic way of delivering and managing these resources mainly in the Asian countries. Among such solutions, it is debated that Cloud computing is the right choice to reduce the expenses of the institutions. This paper describes the common benefits of cloud computing for Shaikh Zayed University. To provide imported and updated information and to deliver daily lectures on time, a physical structure such as (hardware and software) is needed. To attain this objective, the researcher conducted qualitative data to collect the data. Data from different experts were collected using the questionnaires in this field. The results of these survey showed that cloud computing had great role in reducing the Costs, achieved a Collaborating environment and all time Availability

Safety and efficacy of the ChAdOx1 nCoV-19 vaccine (AZD1222) against SARS-CoV-2: an interim analysis of four randomised controlled trials in Brazil, South Africa, and the UK.

BACKGROUND: A safe and efficacious vaccine against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), if deployed with high coverage, could contribute to the control of the COVID-19 pandemic. We evaluated the safety and efficacy of the ChAdOx1 nCoV-19 vaccine in a pooled interim analysis of four trials. METHODS: This analysis includes data from four ongoing blinded, randomised, controlled trials done across the UK, Brazil, and South Africa. Participants aged 18 years and older were randomly assigned (1:1) to ChAdOx1 nCoV-19 vaccine or control (meningococcal group A, C, W, and Y conjugate vaccine or saline). Participants in the ChAdOx1 nCoV-19 group received two doses containing 5 × 1010 viral particles (standard dose; SD/SD cohort); a subset in the UK trial received a half dose as their first dose (low dose) and a standard dose as their second dose (LD/SD cohort). The primary efficacy analysis included symptomatic COVID-19 in seronegative participants with a nucleic acid amplification test-positive swab more than 14 days after a second dose of vaccine. Participants were analysed according to treatment received, with data cutoff on Nov 4, 2020. Vaccine efficacy was calculated as 1 - relative risk derived from a robust Poisson regression model adjusted for age. Studies are registered at ISRCTN89951424 and ClinicalTrials.gov, NCT04324606, NCT04400838, and NCT04444674. FINDINGS: Between April 23 and Nov 4, 2020, 23 848 participants were enrolled and 11 636 participants (7548 in the UK, 4088 in Brazil) were included in the interim primary efficacy analysis. In participants who received two standard doses, vaccine efficacy was 62·1% (95% CI 41·0-75·7; 27 [0·6%] of 4440 in the ChAdOx1 nCoV-19 group vs71 [1·6%] of 4455 in the control group) and in participants who received a low dose followed by a standard dose, efficacy was 90·0% (67·4-97·0; three [0·2%] of 1367 vs 30 [2·2%] of 1374; pinteraction=0·010). Overall vaccine efficacy across both groups was 70·4% (95·8% CI 54·8-80·6; 30 [0·5%] of 5807 vs 101 [1·7%] of 5829). From 21 days after the first dose, there were ten cases hospitalised for COVID-19, all in the control arm; two were classified as severe COVID-19, including one death. There were 74 341 person-months of safety follow-up (median 3·4 months, IQR 1·3-4·8): 175 severe adverse events occurred in 168 participants, 84 events in the ChAdOx1 nCoV-19 group and 91 in the control group. Three events were classified as possibly related to a vaccine: one in the ChAdOx1 nCoV-19 group, one in the control group, and one in a participant who remains masked to group allocation. INTERPRETATION: ChAdOx1 nCoV-19 has an acceptable safety profile and has been found to be efficacious against symptomatic COVID-19 in this interim analysis of ongoing clinical trials. FUNDING: UK Research and Innovation, National Institutes for Health Research (NIHR), Coalition for Epidemic Preparedness Innovations, Bill & Melinda Gates Foundation, Lemann Foundation, Rede D'Or, Brava and Telles Foundation, NIHR Oxford Biomedical Research Centre, Thames Valley and South Midland's NIHR Clinical Research Network, and AstraZeneca

Safety and efficacy of the ChAdOx1 nCoV-19 vaccine (AZD1222) against SARS-CoV-2: an interim analysis of four randomised controlled trials in Brazil, South Africa, and the UK

Background A safe and efficacious vaccine against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), if deployed with high coverage, could contribute to the control of the COVID-19 pandemic. We evaluated the safety and efficacy of the ChAdOx1 nCoV-19 vaccine in a pooled interim analysis of four trials. Methods This analysis includes data from four ongoing blinded, randomised, controlled trials done across the UK, Brazil, and South Africa. Participants aged 18 years and older were randomly assigned (1:1) to ChAdOx1 nCoV-19 vaccine or control (meningococcal group A, C, W, and Y conjugate vaccine or saline). Participants in the ChAdOx1 nCoV-19 group received two doses containing 5 × 1010 viral particles (standard dose; SD/SD cohort); a subset in the UK trial received a half dose as their first dose (low dose) and a standard dose as their second dose (LD/SD cohort). The primary efficacy analysis included symptomatic COVID-19 in seronegative participants with a nucleic acid amplification test-positive swab more than 14 days after a second dose of vaccine. Participants were analysed according to treatment received, with data cutoff on Nov 4, 2020. Vaccine efficacy was calculated as 1 - relative risk derived from a robust Poisson regression model adjusted for age. Studies are registered at ISRCTN89951424 and ClinicalTrials.gov, NCT04324606, NCT04400838, and NCT04444674. Findings Between April 23 and Nov 4, 2020, 23 848 participants were enrolled and 11 636 participants (7548 in the UK, 4088 in Brazil) were included in the interim primary efficacy analysis. In participants who received two standard doses, vaccine efficacy was 62·1% (95% CI 41·0–75·7; 27 [0·6%] of 4440 in the ChAdOx1 nCoV-19 group vs71 [1·6%] of 4455 in the control group) and in participants who received a low dose followed by a standard dose, efficacy was 90·0% (67·4–97·0; three [0·2%] of 1367 vs 30 [2·2%] of 1374; pinteraction=0·010). Overall vaccine efficacy across both groups was 70·4% (95·8% CI 54·8–80·6; 30 [0·5%] of 5807 vs 101 [1·7%] of 5829). From 21 days after the first dose, there were ten cases hospitalised for COVID-19, all in the control arm; two were classified as severe COVID-19, including one death. There were 74 341 person-months of safety follow-up (median 3·4 months, IQR 1·3–4·8): 175 severe adverse events occurred in 168 participants, 84 events in the ChAdOx1 nCoV-19 group and 91 in the control group. Three events were classified as possibly related to a vaccine: one in the ChAdOx1 nCoV-19 group, one in the control group, and one in a participant who remains masked to group allocation. Interpretation ChAdOx1 nCoV-19 has an acceptable safety profile and has been found to be efficacious against symptomatic COVID-19 in this interim analysis of ongoing clinical trials

Multiple Criteria Analysis for Site Suitability of Rice Yields in Prachuap Khiri Khan, Thailand

Southeast Asian countries takes rice as one of their necessary food intake to survive for a day. With a booming population of the third world countries, the need for higher production of rice was sought as one of the priorities of the countries like Thailand to identify areas which are deemed suitable for rice production. Thailand is one of the prominent exporter of rice in the whole world and it is important that Prachuap Khiri khan can go with trends of identifying areas for good rice production that would therefore contribute for the economic improvement of its very own districts up to its own country Thailand. This study aims to identify the suitable areas for good rice production in the province of Prachuap Khirikhan. Factors such as slope, aspect, elevation, land use, road proximity, stream network and rainfall were considered to identify the suitable site for good rice yields. The spatial analysis of ArcGIS software was used in the generation of the different maps. Results shows that the southern portion of the province has a very high suitability of rice production, while the Northwestern portion of the province shows the very low suitability of rice production

رحم مادرکو مستعار لینے کی مختلف صورتیں ۔ احکام واستنباط مسائل

Progeny is a serious issue in family matters. Indeed, posterity is a basic matter of course among human beings. The extraordinary development of medical science in the last few decades and paramount researches regarding artificial techniques to become a parent raise several questions among bioethicist and theologians. These techniques are not only related with science or medical field, but as a matter of fact, it involves many bioethical, religious and law related challenges. This article, therefore, seeks to explicate a very modern mean of treat infertility called surrogacy and surrogate mother according to Islamic jurisprudence in the light of contemporary theological arguments. Although the main point is to elaborate the status and position of surrogacy according to the Islamic perspective. Moreover, other relevant points are also discussed. The article looks at the pertinent problems faced by the society regarding the application of such artificial techniques

Antidiabetic and antihyperlipidemic effects of <em>Artemisia absinthium </em> L., <em>Citrullus colocynthis </em> (L.) Schrad. and <em>Gymnema sylvestre</em> (Retz.) R.Br. ex Sm. on type II diabetes hyperlipidemic patients

233-239Artemisia absinthium L., Citrullus colocynthis (L.) Schrad. and Gymnema sylvestre (Retz.) R.Br. ex Sm. have been used in Asian countries for thousands of years to treat diabetes. This study was conducted to evaluate hypoglycemic and antihyperlipidemic effects in type II hyperlipidemic diabetic patients. Study is blind randomized placebo-controlled clinical trials over 40 days. Individuals were divided randomly into 4 groups 1, 2, 3 & 4. Ten individuals were in each group. Group 1 was allocated for G. sylvestre, 2 for A. absinthium, 3 for C. colocynthis and 4 for placebo. Medication (1.0 g/day) was administered for 40 days. From each individual of each group on day 0, 10, 20, 30 and 40 blood samples were collected in fasting condition. Serum glucose values in group 1 dropped most considerably (p < 0.05). Diabetic individuals of all 3 groups as compared to control and placebo group, showed significantly lowered fasting serum glucose level (p < 0.05). Fasting serum triglycerides, cholesterol, HDL-cholesterol and LDL-cholesterol of all 3 groups were not reduced significantly at (p < 0.05) as compared to control and placebo groups. So it may be suggested that a type II diabetic patient can safely be switched from costly conventional antidiabetic medicine to cheap natural products

Adoption and Implementation of E-Learning Framework for Shaikh Zayed University, Khost, Afghanistan

Ministry of higher education has recently launched an e-learning tool during the global COVID-19 pandemic in Afghanistan. Many higher learning institutions in Afghanistan have implemented e-learning tool because of its effectiveness as a learning approach. However, fever studies have shown that there are still low adoption rate of e-learning in higher education institutions in Afghanistan. This study explored the rate of adoption and an implementation framework of e-learning in Shaikh Zayed University Khost, Afghanistan. The strategy of inquiry is quantitative and the instrument for determining the perceptions of target group is questionnaire. A total of 120 instructors have participated in the survey in which some of them were IT Administrators. The survey result revealed that 37.08% of contents delivery is traditional on chalk and talk based,&nbsp; 47.91% contents delivered by instructors using projector and 31.66% academic staff use lab sessions at Shaikh Zayed University. As a result, the ministry of higher education in Afghanistan needs to have guidelines to help higher education institutions to implement e-learning successfully and efficiently