CONSCIOUS USE OF CODE-SWITCHING TO IMPROVE FLUENCY IN SPOKEN ENGLISH OF BANGLADESHI STUDENTS

Purpose: Present-day English language teaching in Bangladesh, despite adopting Communicative Language Teaching (CLT), focuses more on accuracy (i.e. grammar) than fluency which is proved as a weak strategy. Fluency acquisition in speaking includes pronunciation, but focusing on pronunciation first, slows down the process of becoming a fluent speaker. Methodology: As code-switching exists at the tertiary level in Bangladesh and because of the tremendous fascination of Bangladeshi students towards Bengali, code-switching can be utilized as a tool to improve fluency in spoken English. Thus, this research proposes an alternative to existing approaches. Result: Once desired fluency is achieved; grammar and pronunciation will be emphasized respectively to attain proper speaking skills. The success of this process can be studied in three phases. In the first phase, it examines whether allowing code-switching while speaking English helps Bengali students achieve fluency or not. Applications: This research can be used for universities, teachers, and students. Novelty/Originality: In this research, the model of the Conscious Use of Code-Switching to Improve Fluency in Spoken English of Bangladeshi Students is presented in a comprehensive and complete manner

THE SCENARIOS OF COVID-19 PANDEMIC IN BANGLADESH: ANALYSIS OF DATA IN JULY ANDAUGUST’2020

The outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic quickly surges throughout the world including Bangladesh from the beginning of 2020. To challenge the present detrimental situations, many countries are approving several preventive measures, e.g., international travel bans, isolated office activities, country lockdown, and most importantly social distancing, even though some medications are prescribed in some extent. The government of Bangladesh also took various preventive measures to limit the thunder of corona virus disease 20019 (COVID-19) pandemic. But, the actions are not adequate to face the challenges of COVID-19 in Bangladesh, particularly in the capital city Dhaka, remarkably because of the lower-middle-income economy with one of the world’s densest populations. In Dhaka city, based on the present populations, social distancing is difficult, and with the nominal resources it would be extremely challenging to implement the mitigation measures of COVID-19. Mobile sanitization facilities, temporary quarantine sites and healthcare facilities could help to improve the pandemic effect. A rapid, caring, and empathic collaboration between the government, citizens, and health experts, along with international assistance, can enable the country to minimize the impact of the pandemic. In this review, we summarize the occurrence (RT-PCR based test) and present scenarios of COVID-19 outbreak in Bangladesh, particularly in the Dhaka city analyzing available data in July and August’2020

Efficacy and Economics of Herbicidal Weed Management in Monsoon Rice of Bangladesh: Weed Management in Monsoon Rice of Bangladesh

Weed management is a challenging task in sustainable rice production. Physical and cultural methods of weed control are laborious and expensive, whereas chemical control is cheaper and less time consuming despite of some detrimental effect on environment with its inappropriate application. Considering these points, an experiment was conducted at the Agronomy Field Laboratory of Bangladesh Agricultural University, Mymensingh, Bangladesh during July–December 2015 to find out appropriate weed management practices for inbred and hybrid rice. The experiment comprised of four rice varieties (two inbred; BRRI dhan49 and Binadhan-7, and two hybrids; Dhani gold and Agrodhan-12); and eight herbicidal weed control treatments (season-long weedy or weed free, Pretilachlor fb Penoxsolum or 2,4-D dimethyl amine, Pendimethalin fb Penoxsolum or 2,4-D dimethyl amine, Pretilachlor or Pendimethalin fb one-time hand weeding). Eleven weed species belonging to five families were observed in the experimental plots. The highest weed density and dry weight were found in season-long weedy treatment and the lowest one was found in Pretilachlor fb one-time hand weeding. The highest above ground crop biomass (9.7 t ha-1) and harvest index (46.3%) were obtained from the hybrid variety Agrodhan-12 and the lowest biomass (8.3 t ha-1) was obtained from the inbred variety Binadhan-7. Season long weed free condition resulted the highest above ground crop  biomass (10.9 t ha-1), harvest index (48.7%), highest yield increase over control (213.8), weed control efficiency (100%) and gross return (BDT 141480 ha-1) and the lowest values for all those parameters were obtained from season-long weedy treatment. Season-long weed free treatment combined with Pretilachlor or Pendimethalin fb one-time hand weeding showed the best performance in reducing weed density and increasing above ground crop biomass, but gross return was higher because of high labour wages in these treatments. The highest BCR (2.5) was observed in Pretilachlor fb Penoxsolum. Therefore from economic view point Pretilachlor fb Penoxsolum is the best combination. But from sustainability view point Pretilachlor or Pendimethalin along with one-time hand weeding may be recommended for effective weed management in inbred and hybrid rice during monsoon season

Exploring 55 tropical medicinal plant species available in Bangladesh for their possible allelopathic potentiality

The current research was conducted to investigate the allelopathic properties of 55 medicinal plant species of Bangladesh representing 32 different families. The aqueous leaves or whole plant extract of those plant species was diluted into four different concentrations viz., 1:5, 1:10, 1:15, 1:20 (w/v) and tested against the seedling growth of Raphanus sativus. A control (distilled water without extract) was also maintained in every cases and the bioassay experiment was replicated thrice. The aqueous extract of all these species inhibited both shoot and root length of R. sativus at concentration greater than 1:15 (w/v) except Delonix regia (Fabaceae) and Leucas aspera (Lamiaceae). The inhibitory activity was concentration dependent and root growth was more sensitive than their shoot. Among the plant species, Citrus aurantifolia (Rotaceae), Moringa oleifera (Moringaceae), Annona muricata (Annonaceae), Aegle marmelos (Rutaceae), Cinnamomum tamala (Lauraceae) and Azadirachta indica (Meliaceae) completely (100%) inhibited the shoot and root growth of R. sativus at concentration 1:5 (w/v). Other than this six plant species, 15 out of 49 medicinal plants showed more than 95% shoot and root growth inhibition at the same concentration. The least allelopathic potential plant was Garcinia mangostana (Clusiaceae) that showed on an average 36% growth inhibition followed by Schleichera oleosa (Sapindaceae). Based on these results it can be concluded that among the tested plant species, C. aurantifolia, M. oleifera, A. muricata, A. marmelos, C. tamala, and A. indica are strongly allelopathic and therefore, could be used as potential candidates for the development of eco-friendly natural herbicides

Contamination of Fresh Produce with Antibiotic-Resistant Bacteria and Associated Risks to Human Health: A Scoping Review.

Fresh produce, when consumed raw, can be a source of exposure to antimicrobial residues, antimicrobial-resistant bacteria (ARB) and antimicrobial resistance genes (ARGs) of clinical importance. This review aims to determine: (1) the presence and abundance of antimicrobial residues, ARB and ARGs in fresh agricultural products sold in retail markets and consumed raw; (2) associated health risks in humans; and (3) pathways through which fresh produce becomes contaminated with ARB/ARGs. We searched the Ovid Medline, Web of Science and Hinari databases as well as grey literature, and identified 40 articles for inclusion. All studies investigated the occurrence of multidrug-resistant bacteria, and ten studies focused on ARGs in fresh produce, while none investigated antimicrobial residues. The most commonly observed ARB were E. coli (42.5%) followed by Klebsiella spp. (22.5%), and Salmonella spp. (20%), mainly detected on lettuce. Twenty-five articles mentioned health risks from consuming fresh produce but none quantified the risk. About half of the articles stated produce contamination occurred during pre- and post-harvest processes. Our review indicates that good agricultural and manufacturing practices, behavioural change communication and awareness-raising programs are required for all stakeholders along the food production and consumption supply chain to prevent ARB/ARG exposure through produce

Effective Treatment Strategies for the Removal of Antibiotic-Resistant Bacteria, Antibiotic-Resistance Genes, and Antibiotic Residues in the Effluent From Wastewater Treatment Plants Receiving Municipal, Hospital, and Domestic Wastewater: Protocol for a Systematic Review.

BACKGROUND: The widespread and unrestricted use of antibiotics has led to the emergence and spread of antibiotic-resistant bacteria (ARB), antibiotic-resistance genes (ARGs), and antibiotic residues in the environment. Conventional wastewater treatment plants (WWTPs) are not designed for effective and adequate removal of ARB, ARGs, and antibiotic residues, and therefore, they play an important role in the dissemination of antimicrobial resistance (AMR) in the natural environment. OBJECTIVE: We will conduct a systematic review to determine the most effective treatment strategies for the removal of ARB, ARGs, and antibiotic residues from the treated effluent disposed into the environment from WWTPs that receive municipal, hospital, and domestic discharge. METHODS: We will search the MEDLINE, EMBASE, Web of Science, World Health Organization Global Index Medicus, and ProQuest Environmental Science Collection databases for full-text peer-reviewed journal articles published between January 2001 and December 2020. We will select only articles published in the English language. We will include studies that measured (1) the presence, concentration, and removal rate of ARB/ARGs going from WWTP influent to effluent, (2) the presence, concentration, and types of antibiotics in the effluent, and (3) the possible selection of ARB in the effluent after undergoing treatment processes in WWTPs. At least two independent reviewers will extract data and perform risk of bias assessment. An acceptable or narrative synthesis method will be followed to synthesize the data and present descriptive characteristics of the included studies in a tabular form. The study has been approved by the Ethics Review Board at the International Centre for Diarrhoeal Disease Research, Bangladesh (protocol number: PR-20113). RESULTS: This protocol outlines our proposed methodology for conducting a systematic review. Our results will provide an update to the existing literature by searching additional databases. CONCLUSIONS: Findings from our systematic review will inform the planning of proper treatment methods that can effectively reduce the levels of ARB, ARGs, and residual antibiotics in effluent, thus lowering the risk of the environmental spread of AMR and its further transmission to humans and animals. INTERNATIONAL REGISTERED REPORT IDENTIFIER (IRRID): PRR1-10.2196/33365

A Prospective Study of Arsenic Exposure, Arsenic Methylation Capacity, and Risk of Cardiovascular Disease in Bangladesh

Millions of persons worldwide, including 13 million Americans (U.S. Environmental Protection Agency 2009) and over 50 million in Bangladesh (British Geological Survey 2007), have been chronically exposed to arsenic, a group 1 human carcinogen (International Agency for Research on Cancer 2004), through contaminated drinking water. Arsenic exposure from drinking water has been associated with cardiovascular disease (CVD) (Chen CJ et al. 1996; Chen Y et al. 2011; Chiou et al. 1997; Liao et al. 2012; Tseng et al. 2003; Yuan et al. 2007). However, prospective studies assessing susceptibility to CVD due to arsenic exposure are rare. Arsenic in drinking water is present as inorganic arsenic (iAS). Once ingested, iAs is methylated to monomethylarsonic acid (MMA) and dimethylarsinic acid (DMA). The relative distribution of urinary arsenic metabolites varies from person to person and has been interpreted to reflect arsenic methylation capacity (Hopenhayn-Rich et al. 1996; Vahter 1999). Mechanistic studies have shown that MMAIII is more toxic than iAs or any of the pentavalent metabolites (Petrick et al. 2000; Styblo et al. 2000). Incomplete methylation, indicated by a high percentage of urinary MMA (MMA%), has been consistently related to cancers (Chen YC et al. 2003; Pu et al. 2007; Steinmaus et al. 2006; Yu et al. 2000), and there is some evidence of stronger associations among smokers than nonsmokers (Pu et al. 2007; Steinmaus et al. 2006). However, the association between urinary MMA% and CVD risk is unknown, and research on the combined effects of arsenic and biomarkers of arsenic susceptibility on CVD risk is needed. We conducted a prospective case–cohort study nested in a large prospective cohort to assess associations of arsenic exposure from drinking water and arsenic methylation capacity, indicated using relative distribution of urinary arsenic metabolites, with CVD risk

Nonmalignant Respiratory Effects of Chronic Arsenic Exposure from Drinking Water among Never-Smokers in Bangladesh

BACKGROUND: Arsenic from drinking water has been associated with malignant and nonmalignant respiratory illnesses. The association with nonmalignant respiratory illnesses has not been well established because the assessments of respiratory symptoms may be influenced by recall bias or interviewer bias because participants had visible skin lesions. OBJECTIVES: We examined the relationship of the serum level of Clara cell protein CC 16-a novel biomarker for respiratory illnesses-with well As, total urinary As, and urinary As methylation indices. METHODS: We conducted a cross-sectional study in nonsmoking individuals (n = 241) selected from a large cohort with a wide range of As exposure (0.1-761 mu g/L) from drinking water in Bangladesh. Total urinary As, urinary As metabolites, and serum CC16 were measured in urine and serum samples collected at baseline of the parent cohort study. RESULTS: We observed an inverse association between urinary As and serum CC 16 among persons with skin lesions (beta = -0. 13, p = 0.01). We also observed a positive association between secondary methylation index in urinary As and CC16 levels (beta = 0. 12,,P = 0.05) in the overall study population; the association was stronger among people without skin lesions (beta = 0. 18, p = 0.04), indicating that increased methylation capability may be protective against As-induced respiratory damage. In a subsample of study participants undergoing spirometric measures (n = 3 1), we observed inverse associations between urinary As and predictive FEV1 (forced expiratory volume measured in 1 sec) (r = -0.37; FEV1/forced vital capacity ratio and primary methylation index (r = -0.42, p = 0.01). CONCLUSIONS: The findings suggest that serum CC 16 may be a useful biomarker of epithelial lung damage in individuals with arsenical skin lesions. Also, we observed the deleterious respiratory effects of As exposure at concentrations lower than reported in earlier studies

Effects of hospital facilities on patient outcomes after cancer surgery: an international, prospective, observational study

Background Early death after cancer surgery is higher in low-income and middle-income countries (LMICs) compared with in high-income countries, yet the impact of facility characteristics on early postoperative outcomes is unknown. The aim of this study was to examine the association between hospital infrastructure, resource availability, and processes on early outcomes after cancer surgery worldwide.Methods A multimethods analysis was performed as part of the GlobalSurg 3 study-a multicentre, international, prospective cohort study of patients who had surgery for breast, colorectal, or gastric cancer. The primary outcomes were 30-day mortality and 30-day major complication rates. Potentially beneficial hospital facilities were identified by variable selection to select those associated with 30-day mortality. Adjusted outcomes were determined using generalised estimating equations to account for patient characteristics and country-income group, with population stratification by hospital.Findings Between April 1, 2018, and April 23, 2019, facility-level data were collected for 9685 patients across 238 hospitals in 66 countries (91 hospitals in 20 high-income countries; 57 hospitals in 19 upper-middle-income countries; and 90 hospitals in 27 low-income to lower-middle-income countries). The availability of five hospital facilities was inversely associated with mortality: ultrasound, CT scanner, critical care unit, opioid analgesia, and oncologist. After adjustment for case-mix and country income group, hospitals with three or fewer of these facilities (62 hospitals, 1294 patients) had higher mortality compared with those with four or five (adjusted odds ratio [OR] 3.85 [95% CI 2.58-5.75]; p<0.0001), with excess mortality predominantly explained by a limited capacity to rescue following the development of major complications (63.0% vs 82.7%; OR 0.35 [0.23-0.53]; p<0.0001). Across LMICs, improvements in hospital facilities would prevent one to three deaths for every 100 patients undergoing surgery for cancer.Interpretation Hospitals with higher levels of infrastructure and resources have better outcomes after cancer surgery, independent of country income. Without urgent strengthening of hospital infrastructure and resources, the reductions in cancer-associated mortality associated with improved access will not be realised

Reducing the environmental impact of surgery on a global scale: systematic review and co-prioritization with healthcare workers in 132 countries

Background Healthcare cannot achieve net-zero carbon without addressing operating theatres. The aim of this study was to prioritize feasible interventions to reduce the environmental impact of operating theatres. Methods This study adopted a four-phase Delphi consensus co-prioritization methodology. In phase 1, a systematic review of published interventions and global consultation of perioperative healthcare professionals were used to longlist interventions. In phase 2, iterative thematic analysis consolidated comparable interventions into a shortlist. In phase 3, the shortlist was co-prioritized based on patient and clinician views on acceptability, feasibility, and safety. In phase 4, ranked lists of interventions were presented by their relevance to high-income countries and low–middle-income countries. Results In phase 1, 43 interventions were identified, which had low uptake in practice according to 3042 professionals globally. In phase 2, a shortlist of 15 intervention domains was generated. In phase 3, interventions were deemed acceptable for more than 90 per cent of patients except for reducing general anaesthesia (84 per cent) and re-sterilization of ‘single-use’ consumables (86 per cent). In phase 4, the top three shortlisted interventions for high-income countries were: introducing recycling; reducing use of anaesthetic gases; and appropriate clinical waste processing. In phase 4, the top three shortlisted interventions for low–middle-income countries were: introducing reusable surgical devices; reducing use of consumables; and reducing the use of general anaesthesia. Conclusion This is a step toward environmentally sustainable operating environments with actionable interventions applicable to both high– and low–middle–income countries