Ahlak Felsefesi Ekseninde Günah Kavramı

Humankind has two major conceptions in his world: good and evil, right and wrong, righteousness and sinfulness. This dichotomy is the result of man's freedom; for, if he lacked freedom, he would not have one of these dichotomies and become content only with the other. Sin, being the common name for violating religious commands and prohibitions, and disobeying the will of the Creator, is one of these opposite binaries. Man is sent to this world for being tested. Sin is required in this test in order the expected result to emerge. The absence of sins is the absence of the possibility/right that man might/could lose the test.İnsanoğlunun dünyasında iki temel kavram vardır: Güzel ve çirkin, doğru ve yanlış, sevap ve günâh. Bu ikilemin varlığı insanoğlunun hürriyetinin bir neticesidir. Zira özgürlüğü olmasaydı söz konusu ikilemlerden biri olmayacak diğeri ile zorunlu olarak yetinecekti. Dini emir ve yasaklara karşı gelme ve yaratıcıya başkaldırmanın da ortak adı olan günah da, bu zıt ikilemlerden birisidir. İnsanoğlu bu dünyaya imtihan için gönderilmiştir. Günah, bu imtihandan beklenen neticenin ortaya çıkması için imtihanın bir gereğidir. Günahların olmayışı, insanın imtihanı kaybetme ihtimalinin/hakkının olmaması demektir

Histopathological distribution of thyroid cancers: A retrospective analysis of 570 patients

Aim: Thyroid cancers are the most commonly encountered endocrine system malignancies.  The incidence continues to rise worldwide. Our aim in this study is to investigate the frequency and histopathological subtypes of thyroid cancer in our clinic. Methods: The present study was conducted with 3614 patients who were followed up in our endocrinology and general surgery clinic and operated with the diagnosis of multinodular and/or nodular goiter between 2015 and 2021. The histopathological types and information of patients diagnosed with thyroid cancer were obtained retrospectively from the pathology reports. Among the patients included in the study, a total of 570 people who were reported to have thyroid cancer due to histopathology were included in the study. Results: The data of a total of 3614 biopsy reports were examined for the study. Among these patients, 570 (421 females, 149 males) were operated and whose pathology reports were accessed were included in the study. The mean age of the patients was 49.12±10.4 years. As a result of the operations, malign postoperative tissue histopathology was 98.9% (n=564), and uncertain malignancy potential was reported to be 1.0% (n=6). In our study, the histopathological distribution of thyroid cancers was as follows; thyroid papillary cancer 89.4% (n=510), follicular cancer 7.3% (n=42), medullary cancer 2.1% (n=12), and malignancy potential uncertain 1.0% (n=6). Conclusion: The results of our study suggest that thyroid cancers are more common in women in our country, in parallel with the similar rates reported in the literature, with the increase worldwide

Placental Characteristics Classification of Various Native Turkish Sheep Breeds

Simple Summary The aim of this study was to classify placental characteristics of Akkaraman, Morkaraman, Karayaka, Awassi, Malya, and Bafra native sheep breeds using the hierarchical clustering method. As a result, six breeds were separated into three clusters: the first cluster consisted of Bafra, Karayaka, and Awassi breeds; the second consisted of Akkaraman and Malya breeds; and the third cluster included only the Morkaraman breed. The aim of this study was to classify placental characteristics of Akkaraman, Morkaraman, Karayaka, Awassi, Malya, and Bafra sheep breeds using the hierarchical clustering method. In total, 240 individual data records were used as experimental material. Placental characteristics such as total cotyledon surface area, small and large cotyledon length, small cotyledon depth, etc. were used as explanatory variables to classify the breeds' characteristics. Hierarchical clustering was used with the nearest neighbour method with Euclidean distance in order to classify the sheep breeds' variations. As a result, six breeds were separated into three clusters: the first cluster consisted of Bafra, Karayaka, and Awassi breeds; the second consisted of Akkaraman and Malya breeds; and the third cluster included only the Morkaraman breed. Bafra and Karayaka were pointed as the nearest breeds, with a similarity of 98.7% in terms of placental characteristics. The similarity rate of the Akkaraman and Malya breeds was at a level of 97.5%, whereas it was 96.8% for Bafra, Karayaka, and Awassi breeds. The similarity of Akkaraman, Karayaka, Awassi, Malya, and Bafra sheep breeds was estimated as 95.7%. The overall similarity was found to be at a level of 93.2% among sheep breeds. The outcomes of the study might be useful as a selection tool for reproductivity and can be used to select the breed to be reared

Impact of the COVID-19 pandemic on diabetic ketoacidosis management in the pediatric intensive care unit

Background Diabetic ketoacidosis (DKA) is a common endocrine emergency in pediatric patients. Early presentation to health facilities, diagnosis, and good management in the pediatric intensive care unit (PICU) are crucial for better outcomes in children with DKA. Methods This was a single-center, retrospective cohort study conducted between February 2015 and January 2022. Patients with DKA were divided into two groups according to pandemic status and diabetes diagnosis. Results The study enrolled 59 patients, and their mean age was 11±5 years. Forty (68%) had newly diagnosed type 1 diabetes mellitus (T1DM), and 61% received follow-up in the pre-pandemic period. Blood glucose, blood ketone, potassium, phosphorus, and creatinine levels were significantly higher in the new-onset T1DM group compared with the previously diagnosed group (P=0.01, P=0.02, P<0.001, P=0.01, and P=0.08, respectively). In patients with newly diagnosed T1DM, length of PICU stays were longer than in those with previously diagnosed T1DM (28.5±8.9 vs. 17.3±6.7 hours, p<0.001). The pandemic group was compared with pre-pandemic group, there was a statistically significant difference in laboratory parameters of pH, HCO3, and lactate and also Pediatric Risk of Mortality (PRISM) III score. All patients survived, and there were no neurologic sequelae. Conclusion Patients admitted during the pandemic period were admitted with more severe DKA and had higher PRISM III scores. During the pandemic period, there was an increase in the incidence of DKA in the participating center compared to that before the pandemic

Prevalence, associated factors and outcomes of pressure injuries in adult intensive care unit patients: the DecubICUs study

Funder: European Society of Intensive Care Medicine; doi: http://dx.doi.org/10.13039/501100013347Funder: Flemish Society for Critical Care NursesAbstract: Purpose: Intensive care unit (ICU) patients are particularly susceptible to developing pressure injuries. Epidemiologic data is however unavailable. We aimed to provide an international picture of the extent of pressure injuries and factors associated with ICU-acquired pressure injuries in adult ICU patients. Methods: International 1-day point-prevalence study; follow-up for outcome assessment until hospital discharge (maximum 12 weeks). Factors associated with ICU-acquired pressure injury and hospital mortality were assessed by generalised linear mixed-effects regression analysis. Results: Data from 13,254 patients in 1117 ICUs (90 countries) revealed 6747 pressure injuries; 3997 (59.2%) were ICU-acquired. Overall prevalence was 26.6% (95% confidence interval [CI] 25.9–27.3). ICU-acquired prevalence was 16.2% (95% CI 15.6–16.8). Sacrum (37%) and heels (19.5%) were most affected. Factors independently associated with ICU-acquired pressure injuries were older age, male sex, being underweight, emergency surgery, higher Simplified Acute Physiology Score II, Braden score 3 days, comorbidities (chronic obstructive pulmonary disease, immunodeficiency), organ support (renal replacement, mechanical ventilation on ICU admission), and being in a low or lower-middle income-economy. Gradually increasing associations with mortality were identified for increasing severity of pressure injury: stage I (odds ratio [OR] 1.5; 95% CI 1.2–1.8), stage II (OR 1.6; 95% CI 1.4–1.9), and stage III or worse (OR 2.8; 95% CI 2.3–3.3). Conclusion: Pressure injuries are common in adult ICU patients. ICU-acquired pressure injuries are associated with mainly intrinsic factors and mortality. Optimal care standards, increased awareness, appropriate resource allocation, and further research into optimal prevention are pivotal to tackle this important patient safety threat

Correction to: Prevalence, associated factors and outcomes of pressure injuries in adult intensive care unit patients: the DecubICUs study

The original version of this article unfortunately contained a mistake

Prevalence, associated factors and outcomes of pressure injuries in adult intensive care unit patients: the DecubICUs study

Funder: European Society of Intensive Care Medicine; doi: http://dx.doi.org/10.13039/501100013347Funder: Flemish Society for Critical Care NursesAbstract: Purpose: Intensive care unit (ICU) patients are particularly susceptible to developing pressure injuries. Epidemiologic data is however unavailable. We aimed to provide an international picture of the extent of pressure injuries and factors associated with ICU-acquired pressure injuries in adult ICU patients. Methods: International 1-day point-prevalence study; follow-up for outcome assessment until hospital discharge (maximum 12 weeks). Factors associated with ICU-acquired pressure injury and hospital mortality were assessed by generalised linear mixed-effects regression analysis. Results: Data from 13,254 patients in 1117 ICUs (90 countries) revealed 6747 pressure injuries; 3997 (59.2%) were ICU-acquired. Overall prevalence was 26.6% (95% confidence interval [CI] 25.9–27.3). ICU-acquired prevalence was 16.2% (95% CI 15.6–16.8). Sacrum (37%) and heels (19.5%) were most affected. Factors independently associated with ICU-acquired pressure injuries were older age, male sex, being underweight, emergency surgery, higher Simplified Acute Physiology Score II, Braden score 3 days, comorbidities (chronic obstructive pulmonary disease, immunodeficiency), organ support (renal replacement, mechanical ventilation on ICU admission), and being in a low or lower-middle income-economy. Gradually increasing associations with mortality were identified for increasing severity of pressure injury: stage I (odds ratio [OR] 1.5; 95% CI 1.2–1.8), stage II (OR 1.6; 95% CI 1.4–1.9), and stage III or worse (OR 2.8; 95% CI 2.3–3.3). Conclusion: Pressure injuries are common in adult ICU patients. ICU-acquired pressure injuries are associated with mainly intrinsic factors and mortality. Optimal care standards, increased awareness, appropriate resource allocation, and further research into optimal prevention are pivotal to tackle this important patient safety threat

Klasik İslam Düşüncesinde İki Farklı Tanrı Tasavvuru

Allah’ın varlığı ve mahiyeti konusu İslam düşüncesinin önemli problemlerinden biridir. Kainatı yaratan ve yönetenin, duyularla idrak edilemese de şüphe yok ki zihnin dışında bir varlığı bulunmaktadır. O’nun zâtının ve mahiyetinin duyularla algılanamayışı sebebiyle İslam düşünürleri Allah’ı tanımak için büyük ölçüde Kur’ân’da O’na nispet edilen kavramlardan hareket etmişlerdir. Temel çıkış noktaları aynı olsa da çeşitli sebeplerle birbirinden farklı görüşler ileri sürülmüş, derin fikir ayrılıkları gün yüzüne çıkmıştır. Tanrı tasavvurunun yapısal özellikleri aslında insanın bizatihi kendisinin ve hayata ve tabiata bakışının temelinde yatan en önemli belirleyici unsurdur. Bu makalede, İslam Düşüncesi’nin oluşum sürecinde (tedvin dönemi) ortaya çıkan belli başlı temel iki ekol olan Ehl-i Rey ve Selefiyye olarak isimlendirebileceğimiz görüşler ışığında Tanrı kavramı ele alınacak ve bu görüşlerin ortaya çıkardığı problemler ve çözüm yolları günümüzle de irtibatlandırılmaya çalışılarak eleştirel bir tarzda işlenmeye çalışılacaktır