Corrosion Inhibition Study of Mild Steel in Acidic Medium by Antibiotic Drugs: a Comparative Study

- A comparison of the inhibiting efficiency of antibiotic drugs (ciprofloxacin, cloxacillin, and amoxicillin) on the corrosion of mild steel in 1 mol·L−1 HCl were studied at room temperature using mass loss measurement. The main reason is probably be due to the formation of protective coverage by the inhibitor as other authors reported previously. Adsorption characteristics of the inhibitor has also been studied using simple equation and it was found that drugs inhibits the corrosion of mild steel by being adsorbed on the surface of mild steel by a physical adsorption mechanism. The adsorption of drugs on the mild steel surface was found to be spontaneous and obey the Langmuir adsorption isotherm model. It was observed that the test drug has a promising inhibitory action in acid medium against corrosion of mild steel. Moreover it was revealed that an inhibition efficiency of 80.1 % can be achieved with 3×10-3M ciprofloxacin drug treatment on mild steel

Corrosion Inhibition Study of Mild Steel in Acidic Medium by Antibiotic Drugs: A Comparative Study

Abstract - A comparison of the inhibiting efficiency of antibiotic drugs (ciprofloxacin, cloxacillin, and amoxicillin) on the corrosion of mild steel in 1 mol·L−1 HCl were studied at room temperature using mass loss measurement. The main reason is probably be due to the formation of protective coverage by the inhibitor as other authors reported previously. Adsorption characteristics of the inhibitor has also been studied using simple equation and it was found that drugs inhibits the corrosion of mild steel by being adsorbed on the surface of mild steel by a physical adsorption mechanism. The adsorption of drugs on the mild steel surface was found to be spontaneous and obey the Langmuir adsorption isotherm model. It was observed that the test drug has a promising inhibitory action in acid medium against corrosion of mild steel. Moreover it was revealed that an inhibition efficiency of 80.1 % can be achieved with 3×10-3M ciprofloxacin drug treatment on mild steel.Keywords: Steel corrosion; Antibiotic drugs; Adsorption isotherm; Inhibition mechanism

Highly selective and sensitive macrocycle-based dinuclear foldamer for fluorometric and colorimetric sensing of citrate in water.

The selective detection of citrate anions is essential for various biological functions in living systems. A quantitative assessment of citrate is required for the diagnosis of various diseases in the human body; however, it is extremely challenging to develop efficient fluorescence and color-detecting molecular probes for sensing citrate in water. Herein, we report a macrocycle-based dinuclear foldamer (1) assembled with eosin Y (EY) that has been studied for anion binding by fluorescence and colorimetric techniques in water at neutral pH. Results from the fluorescence titrations reveal that the 1·EY ensemble strongly binds citrate anions, showing remarkable selectivity over a wide range of inorganic and carboxylate anions. The addition of citrate anions to the 1·EY adduct led to a large fluorescence enhancement, displaying a detectable color change under both visible and UV light in water up to 2 μmol. The biocompatibility of 1·EY as an intracellular carrier in a biological system was evaluated on primary human foreskin fibroblast (HF) cells, showing an excellent cell viability. The strong binding properties of the ensemble allow it to be used as a highly sensitive, detective probe for biologically relevant citrate anions in various applications

Repurposing Avasimibe to Inhibit Bacterial Glycosyltransferases

We are interested in identifying and characterizing small molecule inhibitors of bacterial virulence factors for their potential use as anti-virulence inhibitors. We identified from high-throughput screening assays a potential activity for avasimibe, a previously characterized acyl-coenzyme A: cholesterol acyltransferase inhibitor, in inhibiting the NleB and SseK arginine glycosyltransferases from Escherichia coli and Salmonella enterica, respectively. Avasimibe inhibited the activity of the Citrobacter rodentium NleB, E. coli NleB1, and S. enterica SseK1 enzymes, without affecting the activity of the human serine/threonine N-acetylglucosamine (O-GlcNAc) transferase. Avasimibe was not toxic to mammalian cells at up to 200 µM and was neither bacteriostatic nor bactericidal at concentrations of up to 125 µM. Doses of 10 µM avasimibe were sufficient to reduce S. enterica abundance in RAW264.7 macrophage-like cells, and intraperitoneal injection of avasimibe significantly reduced C. rodentium survival in mice, regardless of whether the avasimibe was administered pre- or post-infection. We propose that avasimibe or related derivates created using synthetic chemistry may have utility in preventing or treating bacterial infections by inhibiting arginine glycosyltransferases that are important to virulence

Modeling Bangladesh's gross domestic product using regression approach

This study finds the factors that affect Bangladesh’s Gross Domestic Product (GDP) through regression approach. Stepwise and Ridge regression techniques have been applied to build the suitable regression model. Model adequacy also has been checked and multicollinearity problem is addressed for a plausible model using appropriate remedial measures for each of the model one after another that yields stepwise regression. The multicollinearity problem has also been tried to combat by ridge regression. Finally, the model which is adequate and free from multicollinearity problem after applying the ridge regression has been considered as the credible model for predicting the GDP of Bangladesh. The final model shows that the factors population, imports of goods and services, agriculture value added, manufacturing value added and labor force are positively affecting the GDP of Bangladesh

CSR in major European football leagues in the age of COVID-19: financial vulnerability, mental health and domestic violence

Purpose COVID-19 pandemic has significantly impacted the lives of people and businesses around the world in different ways. France, Spain, Italy and the UK are among the worst affected countries by this pandemic. The purpose of this paper is to identify and compare different corporate social responsibility (CSR) activities taken by the clubs and player of the major football leagues of these four countries to develop a more comprehensive model of intervention. Design/methodology/approach This paper has analyzed the initiatives taken by these football clubs and players to address financial vulnerabilities, mental health problems and domestic violence among the stakeholders and compared them with the existing CSR and humanitarian models. A case study approach has been used to collect and analyze data related to the CSR activities taken by the players and club management. Official websites of the clubs, newspaper and journal articles were among the major sources used to collect data for the paper. Findings Football clubs and players of the four major leagues have raised funds through different campaigns and delivered foods and essential medical supplies to the communities and hospitals to address financial vulnerabilities, mental health issues and domestic violence within their communities during the COVID-19 pandemic. They have provided guidance to their followers using social and television media to improve their physical and mental health during the pandemic. Online competitions, quizzes or virtual hangouts have also been used by the players to engage the stakeholders on a frequent basis. Football clubs have also initiated campaigns to raise awareness within the community on available medical services for the victims of domestic violence and also provided them with shelter, food, medical, legal and online counseling services. Originality/value Football clubs and players of the major leagues were always at the forefront to help the communities and hospitals to address issues related to mental health problems, financial vulnerabilities and domestic violence during the COVID-19 pandemic. The findings of this paper could help and guide other entities in designing a more comprehensive model of CSR interventions during pandemics or crisis situations to address financial vulnerabilities, mental health problems and domestic violence within their communities.©2022 Emerald Publishing Limited. This manuscript version is made available under the Creative Commons Attribution–NonCommercial 4.0 International (CC BY–NC 4.0) license, https://creativecommons.org/licenses/by-nc/4.0/fi=vertaisarvioitu|en=peerReviewed