Relationship between tonic and phasic craving for alcohol.

BackgroundMultiple measures are utilized to assess alcohol craving, often interchangeably. Little is known about the relationship between tonic and phasic craving. This study fills this gap in the literature by examining the association between tonic levels of alcohol craving and phasic craving for alcohol that is provoked by alcohol administration.MethodsForty-three non-treatment seeking problem drinkers underwent an initial interview and two laboratory testing sessions, where either alcohol or a saline placebo was administered intravenously. Tonic craving was assessed via the Penn Alcohol Craving Scale (PACS) and Obsessive Compulsive Drinking Scale (OCDS) at the initial interview. Phasic craving was assessed during the laboratory sessions (i.e., alcohol and saline administrations, single blinded) at baseline and at 3 subsequent breath alcohol concentrations (0.02, 0.04, and 0.06 g/dl).ResultsThere was a main effect of PACS in predicting phasic craving across both saline and alcohol administration conditions (p < 0.05). The OCDS was predictive of phasic craving when alcohol, but not saline, was administered (p = 0.058); the obsessive subscale (p = 0.01), but not the compulsive subscale (p > 0.10), predicted phasic craving during alcohol, as compared to saline administration.ConclusionIn sum, tonic craving captured by the OCDS was predictive of phasic craving during alcohol administration whereas the PACS more generally captured the increase in phasic craving. Therefore, these measures of tonic craving may function differently in capturing the experience of phasic craving. Implications for the utilization of the PACS and OCDS as well as assessments of craving in alcoholism research are discussed

Convergence between the Penn Alcohol Craving Scale and diagnostic interview for the assessment of alcohol craving.

IntroductionThe Penn Alcohol Craving Scale (PACS) is one of the most widely used instruments to measure craving for alcohol. Recent research has suggested that scores on the PACS can be used as a "stand in" for the diagnostic criterion of alcohol craving with a proposed cutoff of >20 on the PACS indicating a "positive" alcohol craving symptom. The present study examined the convergence between the PACS and face-to-face diagnostic interview for the assessment of alcohol craving.MethodA sample of non-treatment seeking heavy drinkers (N = 338) enrolled in experimental studies of AUD completed the PACS as well as a face-to-face diagnostic interview for AUD, which included the craving item from the Semi-Structured Assessment for the Genetics of Alcoholism (SSAGA).ResultsUsing the PACS cut-off score of >20, 12.9% (N = 43) of the sample met criteria for alcohol craving compared to 21% (N = 74) of the sample meeting criteria based on the diagnostic interview. Using the PACS cutoff of >20, sensitivity (i.e., true positive rate) was 41% and specificity (i.e., true negative rate) was 95%. Exploratory analyses suggested that a cut-off score of ≥15 achieved the optimal balance of sensitivity (67%) and specificity (81%) in our sample.ConclusionsAdvancing the assessment of alcohol craving and the conversion from DSM-IV to DSM-5 diagnostic criteria represents an important research direction. The present study recommends that a PACS score cut off of ≥15 should be used as an indicator of clinically significant alcohol craving in community samples of non-treatment seekers

Attitudes Toward Bisexuality According to Sexual Orientation and Gender

Despite increasing support for lesbian and gay individuals, the same degree of tolerance has not extended to bisexual individuals, and bisexual invisibility and biphobia are continuing problems that affect the mental health and well-being of people who are bisexual. There is evidence that attitudes toward people who are bisexual may vary by one\u27s own sexual orientation or gender. In the present study, the authors examined differences in attitudes toward people who are bisexual by sexual orientation and gender. The authors also asked participants who were bisexual to describe their experiences of being stigmatized. This study found significant effects for sexual orientation but not for gender; specifically, heterosexual participants reported significantly more biphobia and negative bisexual attitudes than participants who were gay, lesbian, or bisexual. Further, participants who were bisexuals reported feeling most stigmatized by individuals who were heterosexual. The results of this study indicate that attitudes toward bisexuality differ by sexual orientation but not by gender. The authors suggest implications for the mental health and well-being of people who are bisexual as well as possible interventions

Processes in resilience in offspring of parents with depression

The literature detailing the effects of growing up with a parent with depression is extensive, and there is a burgeoning body of literature delineating processes of resilience in at-risk children. Both of these fields are summarised here, before a more in-depth examination of studies which have brought these two areas together. Only a limited number of studies have explored resilience in offspring of depressed parents. These studies have focused on coping, on factors that aid resilience and on preventive interventions designed to promote resilience. Relevant factors have emerged from this review but less is understood about the processes that underlie resilience. Further research is needed to increase our understanding of both why and how some offspring of depressed parents show positive adaptation despite being at risk

DYNAMICS OF TRAPPED POLARITONS INSTRESSED GaAs QUANTUMWELL-MICROCAVITY STRUCTURES:EXPERIMENTS AND NUMERICAL SIMULATIONS

Microcavity polaritons have been studied for a decade and a half. Soon after their discovery they were proposed as candidates for the observation of BEC in a solid. In consideration of this possibility, microcavity polaritons have been studied experimentally, analytically, and numerically. Most of the numerical studies have been qualitative. This thesis continues that analysis and for the first time fits experimentally obtained distributions with that obtained by numerical simulations.For this thesis, experiments were performed on a GaAs quantum well-microcavity structure. Excitations of this structure are manifested as polaritons when the quantum well excitons are strongly coupled to the cavity mode. The experimental study of these polaritons provides interesting results. The experiments where the polariton density is the highest show that there is accumulation of polaritons in the low energy states near $k=0$. Below this high density it is seen that the distribution becomes flat and maintains that shape as density is decreased. Neither the high density nor the low density data has a thermalized distribution. Can the accumulation at high density be explained with Boson statistics? What can explain the flat, nonthermalized distribution at low densities. To answer these questions a numerical model was developed. The model has shown that the distribuition functions from the experiments can be numerically simulated. The model has shown that the accumulation at $k=0$ is due to Boson statistics. Through the model, an explanation as to why the distribution curves are flat is also provided. This thesis is presented as follows. An introduction to microcavity polaritons and to our experimental system is presented in chapter 1. Chapter 2 describes the scattering processes that regulate the dynamics of the polaritons and the equations that are used in the model. Chapter 3 gives a review of previous numerical models on microcavity polaritons. Chapter 4 describes the experimental techniques used to acquire the data while chapter 5 compares the data with that given by the simulation. Chapter 6 then discusses directions for continued research

Using Mindfulness for Increasing Provider Capacity to Support Inner City Survivors of Violence [English and Spanish versions]

A Spanish translation of this publication is available to download under Additional Files below. Mindfulness is recognized as an evidence-based practice that can improve a person’s physical and emotional health and well-being. This research project examined the cultural relevance and potential acceptability of mindfulness practices by front-line providers working with a low-income community of color affected by gun homicide

Explicit construction of nilpotent covariants in N=4 SYM

Some aspects of correlation functions in N=4 SYM are discussed. Using N=4 harmonic superspace we study two and three-point correlation functions which are of contact type and argue that these contact terms will not affect the non-renormalisation theorem for such correlators at non-coincident points. We then present a perturbative calculation of a five-point function at two loops in N=2 harmonic superspace and verify that it reproduces the derivative of the previously found four-point function with respect to the coupling. The calculation of this four-point function via the five-point function turns out to be significantly simpler than the original direct calculation. This calculation also provides an explicit construction of an N=2 component of an N=4 five-point nilpotent covariant that violates U(1)_Y symmetry.Comment: 20 pages, standard late

Relational ethics, depressive symptoms, and relationship satisfaction in couples in therapy

The purpose of this study was to examine depressive symptoms and relationship satisfaction as problems related to relational ethics in one\u27s family of origin and current partner relationships in a sample of 68 other-sex couples seeking therapy at a large university clinic. We used the Actor Partner Interdependence Model to analyze dyadic data collected prior to beginning therapy. Specifically, we found significant actor effects between relational ethics in one\u27s family of origin and depressive symptoms, as well as between depressive symptoms and low relationship satisfaction for both male and female partners. We also found significant partner effects for relational ethics in current partner relationship, depressive symptoms, and low relationship satisfaction. Clinical application of contextual therapy theory is discussed