Lammfleischerzeugung im ökologischen Landbau

The ecological fat lamb production is a branch of meat production extremely exposed to the turbulences of the market. If sheep meat production shall be based on market requirements, the interests of all market partners have to be considered. The consumers want to have a high meat quality. The carcass performance of lambs is influenced by the fattening system (ecological or usual). With the finishing procedures applied it was possible to produce heavy ecological lambs with a good carcass quality

Минимальные массы проб для анализа показателей качества сырья

Запропоновано методику пошуку мінімальної маси проби для аналізу функцій розподілу збагачувальних показників корисної копалини. На підставі розглянутої методики отримані формули, що визначають мінімальну масу проби у залежності від параметрів підготовки проби.Предложена методика поиска минимальной массы пробы для анализа функций распределения обогатительных показателей полезного ископаемого. На основании рассмотренной методики получены формулы, определяющие минимальную массу пробы в зависимости от параметров подготовки пробы.The technique of the minimum sample mass searching for the analysis of the distribution functions of mineral dressing factors was proposed. Based on the examined methods there were obtained formulas that determined the minimum sample mass as a function of the sample preparation parameters

Glatiramer Acetate Treatment in Multiple Sclerosis-Associated Fatigue—Beneficial Effects on Self-Assessment Scales But Not on Molecular Markers

Although fatigue is a common symptom in multiple sclerosis (MS), its pathomechanisms are incompletely understood. Glatiramer acetate (GA), an immunomodulatory agent approved for treatment of relapsing-remitting MS (RRMS), possesses unique mechanisms of action and has been shown to exhibit beneficial effects on MS fatigue. The objective of this study was to correlate clinical, neuropsychological, and immunological parameters in RRMS patients with fatigue before and during treatment with GA. In a prospective, open-label, multicenter trial, 30 patients with RRMS and fatigue were treated with GA for 12 months. Inclusion criterion was the presence of fatigue as one of the most frequent and disabling symptoms. Before and during treatment, fatigue was assessed using the Fatigue Severity Scale (FSS), the MS-FSS, and the Modified Fatigue Impact Scale (MFIS). In addition, fatigue and quality of life were assessed using the Visual Analog Scales (VAS). Laboratory assessments included screening of 188 parameters using real-time PCR microarrays followed by further analysis of several cytokines, chemokines, and neurotrophic factors. Fatigue self-assessments were completed in 25 patients. After 12 months of treatment with GA, 13 of these patients improved in all three scales (with the most prominent effects on the MFIS), whereas 5 patients had deteriorated. The remaining 7 patients exhibited inconsistent effects within the three scales. Fatigue and overall quality of life had improved, as assessed via VAS. Laboratory assessments revealed heterogeneous mRNA levels of cytokines, chemokines, and neurotrophic factors. In conclusion, we were not able to correlate clinical and molecular effects of GA in patients with RRMS and fatigue

Resiliente Digitalisierung der kritischen Infrastruktur Landwirtschaft - mobil, dezentral, ausfallsicher

Diese Arbeit befasst sich mit der zunehmenden Digitalisierung der kritischen Infrastruktur Ernährungswirtschaft und setzt den Fokus insbesondere auf die dadurch resultierenden informationstechnologischen Folgen bezüglich der Angriffs- und Ausfallsicherheit in der Landwirtschaft und von ihr abhängigen Sektoren. In diesem Kontext wird die Modernisierungen der Landmaschinen und deren Vernetzung sowie das Cloud-Computing in der Landwirtschaft analysiert und zu treffende Maßnahmen bezüglich einer resilienten Struktur erläutert. In vielen Bereichen wird dabei aufgezeigt, dass das Ausfallrisiko der Produktion zugunsten von Vorteilen wie Ertrags- und Qualitätssteigerung vernachlässigt wird. Dieser Beitrag plädiert für eine resiliente Digitalisierung in der Landwirtschaft mit gebrauchstauglichen Sicherheitslösungen, um keine zusätzlichen Aufwände für die Nutzer zu erzeugen und somit die praktische Sicherheit zu erhöhen

Cellular Recognition of Trimyristoylated Peptide or Enterobacterial Lipopolysaccharide via Both TLR2 and TLR4

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Case Report: A Case of Severe Clinical Deterioration in a Patient With Multiple Sclerosis

Tumefactive multiple sclerosis (MS) is a rare variant of MS that may lead to a rapidly progressive clinical deterioration requiring a multidisciplinary diagnostic workup. Our report describes the diagnostic and therapeutic approach of a rare and extremely severe course of MS. A 51-year-old man with an 8-year history of relapsing-remitting MS (RRMS) was admitted with a subacute progressive left lower limb weakness and deterioration of walking ability. After extensive investigations including repeated MRI, microbiological, serological, cerebrospinal fluid (CSF) studies, and finally brain biopsy, the diagnosis of a tumefactive MS lesion was confirmed. Despite repeated intravenous (IV) steroids as well as plasma exchanges and IV foscarnet and ganciclovir owing to low copy numbers of human herpesvirus 6 (HHV-6) DNA in polymerase chain reaction (PCR) analysis, the patient did not recover. The clinical presentation of tumefactive MS is rare and variable. Brain biopsy for histopathological workup should be considered in immunocompromised patients with rapidly progressive clinical deterioration with brain lesions of uncertain cause