2,794 research outputs found

    Sensor Based on Extending the Concept of Fidelity to Classical Waves

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    We propose and demonstrate a remote sensor scheme by applying the quantum mechanical concept of fidelity loss to classical waves. The sensor makes explicit use of time-reversal invariance and spatial reciprocity in a wave chaotic system to sensitively and remotely measure the presence of small perturbations. The loss of fidelity is measured through a classical wave-analog of the Loschmidt echo by employing a single-channel time-reversal mirror to rebroadcast a probe signal into the perturbed system. We also introduce the use of exponential amplification of the probe signal to partially overcome the effects of propagation losses and to vary the sensitivity.Comment: 4 pages, 2 figure

    Addressing the ‘Shift’: Preparing Preservice Secondary Teachers for the Common Core

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    Common Core represents a shift in content-area literacy instruction, broadening from a narrow focus on generalizable skills to also include a disciplinary perspective of literacies specific to the specialized language and habits of thinking within particular subjects. This requires teachers to be knowledgeable in their content and possess competence in pedagogical practices that allow them to scaffold their students’ literacy development within these disciplines. We examined how the implementation of a Disciplinary Literacy Project into a content-area literacy course influenced preservice secondary teachers’ disciplinary literacy practice. The findings suggest structured inquiry into disciplinary communities enhances preservice teachers’ understanding of disciplinary literacy, but this knowledge is not easily transferred into classroom instruction. Implications for future research on disciplinary literacy models and preservice teacher preparation are discussed

    Seeding Techniques for Alfalfa to Improve Subirrigated Meadows

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    Improving quality and quantity of forage harvested from poor condition, subirrigated hay meadows in the Nebraska Sand Hills is critical to the winter forage reserve of livestock producers. Alfalfa (Medicago sativa L.) is the most commonly used legume for meadow improvement. Broadcast seeding (11.2 kg/ha) was compared to sod seeding (11.2 kg/ha) as a method to introduce alfalfa into an alkaline subirrigated meadow (Fluvaquentic Haplustolls). Before seeding, the study area received 78.5 kg/ha phosphorous. Paraquat (0.29 kg/ha) was applied to one-half of the area to suppress plant competition and provide qualitative information on treatment consistency across a range of sod competition. Lo-till sod seeding was accomplished with a power tillage seeder. Seedling density was determined in spring the following year. Broadcast alfalfa had a greater seedling density than sod-seeded alfalfa (38.4 and 19.1 plants/m2, respectively, p=.09). Apparently, paraquat had no effect on seedling establishment and tended to reduce total yield. Yields the year of seeding, using a two harvest scheme, were greater for broadcast compared to sod-seeded alfalfa (p=.02). However, there was no significant difference between yields of broadcast alfalfa and control

    Landmark survival as an end-point for trials in critically ill patients – comparison of alternative durations of follow-up: an exploratory analysis

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    Introduction Interventional ICU trials have followed up patients for variable duration. However, the optimal duration of follow-up for the determination of mortality endpoint in such trials is uncertain. We aimed to determine the most logical and practical mortality end-point in clinical trials of critically ill patients. Methods We performed a retrospective analysis of prospectively collected data involving 369 patients with one of the three specific diagnoses (i) Sepsis (ii) Community acquired pneumonia (iii) Non operative trauma admitted to the Royal Perth Hospital ICU, a large teaching hospital in Western Australia (WA cohort). Their in-hospital and post discharge survival outcome was assessed by linkage to the WA Death Registry. A validation cohort involving 4609 patients admitted during same time period with identical diagnoses from 55 ICUs across Australia (CORE cohort) was used to compare the patient characteristics and in-hospital survival to look at the Australia-wide applicability of the long term survival data from the WA cohort. Results The long term outcome data of the WA cohort indicate that mortality reached a plateau at 90 days after ICU admission particularly for sepsis and pneumonia. Mortality after hospital discharge before 90 days was not uncommon in these two groups. Severity of acute illness as measured by the total number of organ failures or acute physiology score was the main predictor of 90-day mortality. The adjusted in-hospital survival for the WA cohort was not significantly different from that of the CORE cohort in all three diagnostic groups; sepsis (P = 0.19), community acquired pneumonia (P = 0.86), non-operative trauma (P = 0.47). Conclusions A minimum of 90 days follow-up is necessary to fully capture the mortality effect of sepsis and community acquired pneumonia. A shorter period of follow-up time may be sufficient for non-operative trauma

    The role of religion in the longer-range future, April 6, 7, and 8, 2006

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    This repository item contains a single issue of the Pardee Conference Series, a publication series that began publishing in 2006 by the Boston University Frederick S. Pardee Center for the Study of the Longer-Range Future. This conference that took place during April 6, 7, and 8, 2006. Co-organized by David Fromkin, Director, Frederick S. Pardee Center for the Study of the Longer-Range Future, and Ray L. Hart, Dean ad interim Boston University School of TheologyThe conference brought together some 40 experts from various disciplines to ponder upon the “great dilemma” of how science, religion, and the human future interact. In particular, different panels looked at trends in what is happening to religion around the world, questions about how religion is impacting the current political and economic order, and how the social dynamics unleashed by science and by religion can be reconciled.Carnegie Council on Ethics and International Affair

    Minicircle DNA provide enhanced and prolonged transgene expression following airway gene transfer

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    Gene therapy for cystic fibrosis using non-viral, plasmid-based formulations has been the subject of intensive research for over two decades but a clinically viable product has yet to materialise in large part due to inefficient transgene expression. Minicircle DNA give enhanced and more persistent transgene expression compared to plasmid DNA in a number of organ systems but has not been assessed in the lung. In this study we compared minicircle DNA with plasmid DNA in transfections of airway epithelial cells. In vitro, luciferase gene expression from minicircles was 5-10-fold higher than with plasmid DNA. In eGFP transfections in vitro both the mean fluorescence intensity and percentage of cells transfected was 2-4-fold higher with minicircle DNA. Administration of equimolar amounts of DNA to mouse lungs resulted in a reduced inflammatory response and more persistent transgene expression, with luciferase activity persisting for 2 weeks from minicircle DNA compared to plasmid formulations. Transfection of equal mass amounts of DNA in mouse lungs resulted in a 6-fold increase in transgene expression in addition to more persistent transgene expression. Our findings have clear implications for gene therapy of airway disorders where plasmid DNA transfections have so far proven inefficient in clinical trials

    Experimental Test of Universal Conductance Fluctuations by means of Wave-Chaotic Microwave Cavities

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    The mathematical equivalence of the time-independent Schrodinger equation and the Helmholtz equation is exploited to provide a novel means of studying universal conductance fluctuations in ballistic chaotic mesoscopic systems using a two-dimensional microwave-cavity. The classically chaotic ray trajectories within a suitably-shaped microwave cavity play a role analogous to that of the chaotic dynamics of non-interacting electron transport through a ballistic quantum dot in the absence of thermal fluctuations. The microwave cavity is coupled through two single-mode ports and the effect of non-ideal coupling between the ports and cavity is removed by a previously developed method based on the measured radiation impedance matrix. The Landauer-Buttiker formalism is applied to obtain the conductance of a corresponding mesoscopic quantum-dot device. We find good agreement for the probability density functions (PDFs) of the experimentally derived surrogate conductance, as well as its mean and variance, with the theoretical predictions of Brouwer and Beenakker. We also observe a linear relation between the quantum dephasing parameter and the cavity ohmic loss parameter.Comment: 7 Pages,5 Figures (all figures in Color). Submitted to Phys. Rev. B. Updated with Referee/Editor comment

    Response Variability in Naming: A Computational Study

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