61,878 research outputs found

    The Cytoscan (TM) model E-II, a new reflectance microscope for intravital microscopy: Comparison with the standard fluorescence method

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    The Cytoscan(TM) Model E-II (Cytometrics Inc., Philadelphia, Pa., USA) is a newly developed instrument which functions as an intravital microscope and is small and easily portable. Through the use of orthogonal polarization spectral (OPS) imaging, the Cytoscan Model E-II delivers images of the microcirculation which are comparable to those achieved with intravital fluorescence videomicroscopy (IFM), but without the use of fluorescent dyes. The purpose of this study was to validate the Cytoscan Model E-II instrument against IFM. The experiments were carried out on striated muscle in the dorsal skinfold chamber of the awake Syrian hamster. The following parameters were measured in identical regions of interest in the same animal under baseline conditions and 0.5 and 2 h after a 4-hour period of pressure-induced ischemia: arteriolar diameter, venular diameter and venular red blood cell velocity. Bland-Altman plots showed good agreement between the two techniques for venular red blood cell velocity. As expected, arteriolar and venular diameters as measured by the Cytoscan were on average 5 mum smaller than the values from IFM, since the Cytoscan measures the red blood cell column width and IFM measures luminal diameter. Thus, OPS imaging can be used to make valid measurements of microvascular diameter and red blood cell velocity in tissues. Copyright (C) 2000 S. Karger AG, Basel

    Renormalization group for the probability distribution of magnetic impurities in a random-field Ï•4\phi^4 model

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    Extending the usual Ginzburg-Landau theory for the random-field Ising model, the possibility of dimensional reduction is reconsidered. A renormalization group for the probability distribution of magnetic impurities is applied. New parameters corresponding to the extra Ï•4\phi^4 coupling constants in the replica Hamiltonian are introduced. Although they do not affect the critical phenomena near the upper critical dimension, they can when dimensions are lowered.Comment: 16 pages, 11 figures, revte

    Wind tunnel investigations of model rotor noise at low tip speeds

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    Experimental and related analytical results on model rotor rotational and broadband noise obtained in the anechoic wind tunnel and rotor facility are summarized. Factors studied include various noise sources, effects of helicopter performance parameters on noise generated by a model main rotor, appropriate scaling laws for the various types of main rotor noise, and the effects of intensity and size scales of injected turbulence on the intensity and spectra of broadband noise

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    Ordering and Melting in Colloidal Molecular Crystal Mixtures

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    We show in simulations that a rich variety of novel orderings such as pinwheel and star states can be realized for colloidal molecular crystal mixtures at rational ratios of the number of colloids to the number of minima from an underlying periodic substrate. These states can have multi-step melting transitions and also show coexistence in which one species disorders while the other species remains orientationally disordered. For other mixtures, only partially ordered or frustrated states form.Comment: 4 pages, 4 postscript figure

    A structure in the early Universe at z 1.3 that exceeds the homogeneity scale of the R-W concordance cosmology

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    A Large Quasar Group (LQG) of particularly large size and high membership has been identified in the DR7QSO catalogue of the Sloan Digital Sky Survey. It has characteristic size (volume^1/3) ~ 500 Mpc (proper size, present epoch), longest dimension ~ 1240 Mpc, membership of 73 quasars, and mean redshift = 1.27. In terms of both size and membership it is the most extreme LQG found in the DR7QSO catalogue for the redshift range 1.0 = 1.28, which is itself one of the more extreme examples. Their boundaries approach to within ~ 2 deg (~ 140 Mpc projected). This new, huge LQG appears to be the largest structure currently known in the early universe. Its size suggests incompatibility with the Yadav et al. scale of homogeneity for the concordance cosmology, and thus challenges the assumption of the cosmological principle

    High efficiency photon counting using stopped light

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    Single-photon detection and photon counting play a central role in a large number of quantum communication and computation protocols. While the efficiency of state-of-the-art photo-detectors is well below the desired limits, quantum state measurements in trapped ions can be carried out with efficiencies approaching 100%. Here, we propose a method that can in principle achieve ideal photon counting, by combining the techniques of photonic quantum memory and ion-trap fluorescence detection: after mapping the quantum state of a propagating light pulse onto metastable collective excitations of a trapped cold atomic gas, it is possible to monitor the resonance fluorescence induced by an additional laser field that only couples to the metastable excited state. Even with a photon collection/detection efficiency as low as 10%, it is possible to achieve photon counting with efficiency approaching 100%.Comment: 4 page

    Diluted Networks of Nonlinear Resistors and Fractal Dimensions of Percolation Clusters

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    We study random networks of nonlinear resistors, which obey a generalized Ohm's law, V∼IrV\sim I^r. Our renormalized field theory, which thrives on an interpretation of the involved Feynman Diagrams as being resistor networks themselves, is presented in detail. By considering distinct values of the nonlinearity r, we calculate several fractal dimensions characterizing percolation clusters. For the dimension associated with the red bonds we show that dred=1/νd_{\scriptsize red} = 1/\nu at least to order {\sl O} (\epsilon^4), with ν\nu being the correlation length exponent, and ϵ=6−d\epsilon = 6-d, where d denotes the spatial dimension. This result agrees with a rigorous one by Coniglio. Our result for the chemical distance, d_{\scriptsize min} = 2 - \epsilon /6 - [ 937/588 + 45/49 (\ln 2 -9/10 \ln 3)] (\epsilon /6)^2 + {\sl O} (\epsilon^3) verifies a previous calculation by one of us. For the backbone dimension we find D_B = 2 + \epsilon /21 - 172 \epsilon^2 /9261 + 2 (- 74639 + 22680 \zeta (3))\epsilon^3 /4084101 + {\sl O} (\epsilon^4), where ζ(3)=1.202057...\zeta (3) = 1.202057..., in agreement to second order in ϵ\epsilon with a two-loop calculation by Harris and Lubensky.Comment: 29 pages, 7 figure
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