125 research outputs found
Knowledge Utopias: An epistemological perspective on the convergence of museums, libraries and archives
Since 2005, convergence of museums, libraries and archives has emerged as a prominent trend in both the international and Australia collection sectors, made manifest through the development of digital platforms that allow integrated access to diverse collection databases, as well as collaborations and mergers of bricks-and-mortar cultural institutions to incorporate various types of collections and professional disciplines. The convergence phenomenon has led to significant investments in technology and infrastructure, provoking considerable scholarly and professional discourse across collecting domains. Yet, the existence of only a handful of empirical studies reflects a nascent field of study where the majority of research is characterised by inventory-style attempts to quantify and classify types of collaborative projects. This thesis extends current research by examining convergence through a dual commitment to both theory and fieldwork. Focussing on the interpretation of museum collections within converged institutions, I combine conceptual analysis of the epistemological implications of convergence with five detailed case studies of converged organisations in Australia and New Zealand. In a museological context, the research explores ways in which the integration of collecting institutions influences understandings of objects through its impact on museum practices. The findings suggest that convergence not only produces a new institutional framework for museum practice, but also that the integration of collecting institutions has the potential to reshape fundamental understandings of identity, place, heritage and culture
Structural Brain Correlates of Childhood Inhibited Temperament: An ENIGMA-Anxiety Mega-analysis
Mega‐analysis methods in ENIGMA: the experience of the generalized anxiety disorder working group
Pathways through Adolescenc
Mega-analysis methods in ENIGMA: the experience of the generalized anxiety disorder working group
The ENIGMA group on Generalized Anxiety Disorder (ENIGMA‐Anxiety/GAD) is part of a broader effort to investigate anxiety disorders using imaging and genetic data across multiple sites worldwide. The group is actively conducting a mega‐analysis of a large number of brain structural scans. In this process, the group was confronted with many methodological challenges related to study planning and implementation, between‐country transfer of subject‐level data, quality control of a considerable amount of imaging data, and choices related to statistical methods and efficient use of resources. This report summarizes the background information and rationale for the various methodological decisions, as well as the approach taken to implement them. The goal is to document the approach and help guide other research groups working with large brain imaging data sets as they develop their own analytic pipelines for mega‐analyses
ENIGMA-anxiety working group : Rationale for and organization of large-scale neuroimaging studies of anxiety disorders
Altres ajuts: Anxiety Disorders Research Network European College of Neuropsychopharmacology; Claude Leon Postdoctoral Fellowship; Deutsche Forschungsgemeinschaft (DFG, German Research Foundation, 44541416-TRR58); EU7th Frame Work Marie Curie Actions International Staff Exchange Scheme grant 'European and South African Research Network in Anxiety Disorders' (EUSARNAD); Geestkracht programme of the Netherlands Organization for Health Research and Development (ZonMw, 10-000-1002); Intramural Research Training Award (IRTA) program within the National Institute of Mental Health under the Intramural Research Program (NIMH-IRP, MH002781); National Institute of Mental Health under the Intramural Research Program (NIMH-IRP, ZIA-MH-002782); SA Medical Research Council; U.S. National Institutes of Health grants (P01 AG026572, P01 AG055367, P41 EB015922, R01 AG060610, R56 AG058854, RF1 AG051710, U54 EB020403).Anxiety disorders are highly prevalent and disabling but seem particularly tractable to investigation with translational neuroscience methodologies. Neuroimaging has informed our understanding of the neurobiology of anxiety disorders, but research has been limited by small sample sizes and low statistical power, as well as heterogenous imaging methodology. The ENIGMA-Anxiety Working Group has brought together researchers from around the world, in a harmonized and coordinated effort to address these challenges and generate more robust and reproducible findings. This paper elaborates on the concepts and methods informing the work of the working group to date, and describes the initial approach of the four subgroups studying generalized anxiety disorder, panic disorder, social anxiety disorder, and specific phobia. At present, the ENIGMA-Anxiety database contains information about more than 100 unique samples, from 16 countries and 59 institutes. Future directions include examining additional imaging modalities, integrating imaging and genetic data, and collaborating with other ENIGMA working groups. The ENIGMA consortium creates synergy at the intersection of global mental health and clinical neuroscience, and the ENIGMA-Anxiety Working Group extends the promise of this approach to neuroimaging research on anxiety disorders
Visual cues of oviposition sites and spectral sensitivity of Cydia strobilella L.
We investigated whether the spruce seed moth (Cydia so-obilella L., Tortricidae: Grapholitini), an important pest in seed orchards of Norway spruce (Picea abies (L.) Karst.), can make use of the spectral properties of its host when searching for flowers to oviposit on. Spectral measurements showed that the flowers, and the cones they develop into, differ from a background of P. abies needles by a higher reflectance of long wavelengths. These differences increase as the flowers develop into mature cones. Electroretinograms (ERGs) in combination with spectral adaptation suggest that C. strobilella has at least three spectral types of photoreceptor; an abundant green-sensitive receptor with maximal sensitivity at wavelength lambda(max) = 526 nm, a blue-sensitive receptor with kr a = 436 nm, and an ultraviolet-sensitive receptor with lambda(max) = 352 nm. Based on our spectral measurements and the receptor properties inferred from the ERGs, we calculated that open flowers, which are suitable oviposition sites, provide detectable achromatic, but almost no chromatic contrasts to the background of needles. In field trials using traps of different spectral properties with or without a female sex pheromone lure, only pheromone-baited traps caught moths. Catches in baited traps were not correlated with the visual contrast of the traps against the background. Thus, visual contrast is probably not the primary cue for finding open host flowers, but it could potentially complement olfaction as a secondary cue, since traps with certain spectral properties caught significantly more moths than others
Structural brain correlates of childhood inhibited temperament: an ENIGMA-Anxiety Mega-analysis
NWORubicon 019.201SG.022Pathways through Adolescenc
The long and winding road leading to the successful introgression of downy mildew resistance into onion
Neotropical ant-plant Triplaris americana attracts Pseudomyrmex mordax ant queens during seedling stages
The association between the myrmecophyte Triplaris and ants of the genus Pseudomyrmex is an often-reported example of mutualism in the Neotropics. The ants colonize the hollow stems of their hosts, and in exchange, the plants benefit from a reduced degree of herbivory. The previous studies have shown that workers can discriminate their host from other plants, including a closely related species. Little is known about how queens locate their host during the colonization process, but it has been suggested that host recognition is mediated by volatiles. Since queens of Pseudomyrmex mordax colonize their hosts during the seedling stage, we hypothesized that queens would discriminate leaves of seedlings from adult plants. To evaluate our hypothesis, we used a two-sided olfactometer, to test the preference of queens towards different leaf and plant ages of Triplaris americana. Virgin queens of Pseudomyrmex mordax preferred seedlings over adult plants, as well as plant leaves over empty controls, showing no discrimination for leaf age. Our results suggest that the volatiles virgin queens recognize are either produced or are more abundant at the early growing stage of the host when colonization is crucial for the host's survival. © 2017, The Author(s)
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