7,362 research outputs found
Changes in precipitation and river flow in northeast Turkey: associations with the North Atlantic Oscillation
This paper explores the relationships between the North Atlantic Oscillation (NAO) index and precipitation and river flow over northeast Turkey. Precipitation totals and maximum, mean and minimum river flow are analysed at the seasonal scale for 12 and 10 stations, respectively. Pearson’s and Mann-Kendall correlation tests are applied to assess relationships between the NAO index and precipitation and river flow metrics, and to detect trends in time-series. Autumn precipitation totals display significant increasing trends, especially for coastal stations, while inland stations show significant increasing trends for spring precipitation. Minimum and maximum river flow decreases significantly for spring and summer. This tendency implies varying conditions towards a drier regime. Seasonal precipitation patterns show a negative association with the NAO for December–January–February (DJF), March–April–May (MAM) and September–October–November (SON) for some stations. Positive associations between the NAO and winter-extended winter (December–March) river flows are detected for some stations in northeast Turkey
Alternate multiple-outer-planet missions using a Saturn-Jupiter flyby sequence
A study has been made of a method for providing more frequent launch opportunities for multiple-planet Grand Tour type missions to the outer solar system. A Saturn-Jupiter flyby sequence was used in the analysis to initiate the mission instead of the normal Jupiter-Saturn sequence. The Saturn-first approach is shown to yield several new launch opportunities following the 1980 cutoff date for Jupiter-first missions. Results are given for various two-planet, three-planet, and four-planet Jupiter-first and Saturn-first missions. A unique five-planet Saturn-first mission and a Saturn-Jupiter flyby which returns to earth are also discussed. Mission performance is evaluated for each flyby technique by comparing Saturn-first and Jupiter-first missions with respect to launch energy requirements, available launch windows, planetary encounter conditions, and total mission times
Flutter Investigation of 60 Degree to 80 Degree Delta-Planform Surfaces at a Mach Number of 7.0
The flutter characteristics of a series of half-span delta surfaces which had leading-edge sweep angles ranging from 60 degrees to 80 degrees were investigated in helium flaw at a Mach number of 7.0 in the Langley hypersonic aeroelasticity tunnel. For each value of sweep angle both wedge and double-wedge airfoil sections were tested at two pitch-axis positions, The models were mounted so that a rigid-body flapping-pitching type of flutter was encountered. Analysis of the results and comparison with theory show that the wedge models are more stable than the corresponding double-wedge models; the pitch-axis location at or near the center of gravity is more stable than the more forward location; the effects of leading-edge sweep angle on the flutter characteristics appear to be small; and an uncoupled-mode piston-theory analysis gave the best agreement with the experimental results
Urban and regional planning proposal no. Y-10-066-001
There are no author-identified significant results in this report. A program has been completed to print out the radiance values for any specified combination of the four MSS bands for a specified sector of an image. A program to map intensities for any band is being written. An investigation of the characteristics of cities in the Brevard County area, as seen by ERTS-1, has been started. Investigation has not been completed, however, results initially obtained are presented. A Digicol viewer was used to determine the relative reflectance of cities (and other developed sectors) in the area. This was done by a combination of two methods: (1) varying the offset control so that the brightest spot appeared first, followed by the second brightest spot; and (2) reading the relative light transmissions at selected positions. A band 5 image was used and the results, in order of maximum reflectance apparent within the sector, are given
Identifying multiple detachment horizons and an evolving thrust history through cross-section restoration and appraisal in the Moine Thrust Belt, NW Scotland
Peer reviewedPublisher PD
Trogocytosis by Entamoeba histolytica Mediates Acquisition and Display of Human Cell Membrane Proteins and Evasion of Lysis by Human Serum.
We previously showed that Entamoeba histolytica kills human cells through a mechanism that we termed trogocytosis ("trogo-" means "nibble"), due to its resemblance to trogocytosis in other organisms. In microbial eukaryotes like E. histolytica, trogocytosis is used to kill host cells. In multicellular eukaryotes, trogocytosis is used for cell killing and cell-cell communication in a variety of contexts. Thus, nibbling is an emerging theme in cell-cell interactions both within and between species. When trogocytosis occurs between mammalian immune cells, cell membrane proteins from the nibbled cell are acquired and displayed by the recipient cell. In this study, we tested the hypothesis that through trogocytosis, amoebae acquire and display human cell membrane proteins. We demonstrate that E. histolytica acquires and displays human cell membrane proteins through trogocytosis and that this leads to protection from lysis by human serum. Protection from human serum occurs only after amoebae have undergone trogocytosis of live cells but not phagocytosis of dead cells. Likewise, mutant amoebae defective in phagocytosis, but unaltered in their capacity to perform trogocytosis, are protected from human serum. Our studies are the first to reveal that amoebae can display human cell membrane proteins and suggest that the acquisition and display of membrane proteins is a general feature of trogocytosis. These studies have major implications for interactions between E. histolytica and the immune system and also reveal a novel strategy for immune evasion by a pathogen. Since other microbial eukaryotes use trogocytosis for cell killing, our findings may apply to the pathogenesis of other infections.IMPORTANCE Entamoeba histolytica causes amoebiasis, a potentially fatal diarrheal disease. Abscesses in organs such as the liver can occur when amoebae are able to breach the intestinal wall and travel through the bloodstream to other areas of the body. Therefore, understanding how E. histolytica evades immune detection is of great interest. Here, we demonstrate for the first time that E. histolytica acquires and displays human cell membrane proteins by taking "bites" of human cell material in a process named trogocytosis ("trogo-" means "nibble"), and that this allows amoebae to survive in human serum. Display of acquired proteins through trogocytosis has been previously characterized only in mammalian immune cells. Our study suggests that this is a more general feature of trogocytosis not restricted to immune cells and broadens our knowledge of eukaryotic biology. These findings also reveal a novel strategy for immune evasion by a pathogen and may apply to the pathogenesis of other infections
Castleman disease and lymphocytic interstitial pneumonia: a complex diagnostic and management challenge
No abstract available
Planning applications in east central Florida
The author has identified the following significant results. Lake Apopka and three lakes downstream of it (Dora, Eustis, and Griffin) are in an advanced state of eutrophication with high algal concentrations. This feature has shown up consistently on ERTS-1 images in the form of a characteristic water color for those lakes. As expected, EREP photographs also show a characteristic color for those lakes. What was not expected is that Lake Griffin shows a clear pattern of this coloration. Personnel familiar with the lake believe that the photograph does, indeed, show an algal bloom. It is reported that the algal concentration is often significantly higher in the southern portion of the lake. What the photograph shows that was not otherwise known is the pattern of the algal bloom. A similar, but less pronounced, effect is seen in Lake Tohopekaliga. Personnel stationed at Kissimmee reported that there was an algal bloom on that lake at the time of the EREP pass and that its extent corresponded approximately to that shown on the photograph. Again, the EREP photograph gives information about the extent of the bloom that could not be obtained practically by sampling. ERTS-1 images give some indication of this algal distribution on Lake Griffin in some cases, but are inconclusive
- …