258 research outputs found
Biermann Mechanism in Primordial Supernova Remnant and Seed Magnetic Fields
We study generation of magnetic fields by the Biermann mechanism in the
pair-instability supernovae explosions of first stars. The Biermann mechanism
produces magnetic fields in the shocked region between the bubble and
interstellar medium (ISM), even if magnetic fields are absent initially. We
perform a series of two-dimensional magnetohydrodynamic simulations with the
Biermann term and estimate the amplitude and total energy of the produced
magnetic fields. We find that magnetic fields with amplitude
G are generated inside the bubble, though the amount of
magnetic fields generated depend on specific values of initial conditions. This
corresponds to magnetic fields of erg per each supernova
remnant, which is strong enough to be the seed magnetic field for galactic
and/or interstellar dynamo.Comment: 12 pages, 3 figure
The interrelation between the generation of large-scale electric fields and that of large-scale magnetic fields during inflation
The interrelation between the generation of large-scale electric fields and
that of large-scale magnetic fields due to the breaking of the conformal
invariance of the electromagnetic field in inflationary cosmology is studied.
It is shown that if large-scale magnetic fields with a sufficiently large
amplitude are generated during inflation, the generation of large-scale
electric fields is suppressed, and vice versa. Furthermore, a physical
interpretation of the result and its cosmological significance are considered.Comment: 12 pages, no figure, title changed, typos correcte
MFG-E8, a clearance glycoprotein of apoptotic cells, as a new marker of disease severity in chronic obstructive pulmonary disease
Primordial magnetic fields from second-order cosmological perturbations: Tight coupling approximation
We explore the possibility of generating large-scale magnetic fields from
second-order cosmological perturbations during the pre-recombination era. The
key process for this is Thomson scattering between the photons and the charged
particles within the cosmic plasma. To tame the multi-component interacting
fluid system, we employ the tight coupling approximation. It is shown that the
source term for the magnetic field is given by the vorticity, which signals the
intrinsically second-order quantities, and the product of the first order
perturbations. The vorticity itself is sourced by the product of the
first-order quantities in the vorticity evolution equation. The magnetic fields
generated by this process are estimated to be Gauss on the
horizon scale at the recombination epoch. Although our rough estimate suggests
that the current generation mechanism can work even on smaller scales, more
careful investigation is needed to make clear whether it indeed works in a wide
range of spatial scales.Comment: 10pages, minor corrections, accepted for publication in Class. Quant.
Gra
Outstanding Charge Mobility by Band Transport in Two-Dimensional Semiconducting Covalent Organic Frameworks
[Image: see text] Two-dimensional covalent organic frameworks (2D COFs) represent a family of crystalline porous polymers with a long-range order and well-defined open nanochannels that hold great promise for electronics, catalysis, sensing, and energy storage. To date, the development of highly conductive 2D COFs has remained challenging due to the finite π-conjugation along the 2D lattice and charge localization at grain boundaries. Furthermore, the charge transport mechanism within the crystalline framework remains elusive. Here, time- and frequency-resolved terahertz spectroscopy reveals intrinsically Drude-type band transport of charge carriers in semiconducting 2D COF thin films condensed by 1,3,5-tris(4-aminophenyl)benzene (TPB) and 1,3,5-triformylbenzene (TFB). The TPB–TFB COF thin films demonstrate high photoconductivity with a long charge scattering time exceeding 70 fs at room temperature which resembles crystalline inorganic materials. This corresponds to a record charge carrier mobility of 165 ± 10 cm(2) V(–1) s(–1), vastly outperforming that of the state-of-the-art conductive COFs. These results reveal TPB–TFB COF thin films as promising candidates for organic electronics and catalysis and provide insights into the rational design of highly crystalline porous materials for efficient and long-range charge transport
MFGE8 does not influence chorio-retinal homeostasis or choroidal neovascularization in vivo
Purpose: Milk fat globule-epidermal growth factor-factor VIII (MFGE8) is necessary for diurnal outer segment phagocytosis and promotes VEGF-dependent neovascularization. The prevalence of two single nucleotide polymorphisms (SNP) in MFGE8 was studied in two exsudative or “wet” Age-related Macular Degeneration (AMD) groups and two corresponding control groups. We studied the effect of MFGE8 deficiency on retinal homeostasis with age and on choroidal neovascularization (CNV) in mice.
Methods: The distribution of the SNP (rs4945 and rs1878326) of MFGE8 was analyzed in two groups of patients with “wet” AMD and their age-matched controls from Germany and France. MFGE8-expressing cells were identified in Mfge8+/− mice expressing ß-galactosidase. Aged Mfge8+/− and Mfge8−/− mice were studied by funduscopy, histology, electron microscopy, scanning electron microscopy of vascular corrosion casts of the choroid, and after laser-induced CNV.
Results: rs1878326 was associated with AMD in the French and German group. The Mfge8 promoter is highly active in photoreceptors but not in retinal pigment epithelium cells. Mfge8−/− mice did not differ from controls in terms of fundus appearance, photoreceptor cell layers, choroidal architecture or laser-induced CNV. In contrast, the Bruch's membrane (BM) was slightly but significantly thicker in Mfge8−/− mice as compared to controls.
Conclusions: Despite a reproducible minor increase of rs1878326 in AMD patients and a very modest increase in BM in Mfge8−/− mice, our data suggests that MFGE8 dysfunction does not play a critical role in the pathogenesis of AMD
Spectral evolution of dark asteroid surfaces induced by space weathering over a decade
The surface of airless bodies like asteroids in the Solar System are known to
be affected by space weathering. Experiments simulating space weathering are
essential for studying the effects of this process on meteorite samples, but
the problem is that the time spent to reproduce space weathering in these
experiments is billions of times shorter than the actual phenomenon. In
December 2010, the T-type asteroid 596 Scheila underwent a collision with a
few-tens-of-meters impactor. A decade later, there is an opportunity to study
how the surface layer of this asteroid is being altered by space weathering
after the impact. To do so, we performed visible spectrophotometric and
near-infrared spectroscopic observations of 596 Scheila. The acquired spectrum
is consistent with those observed shortly after the 2010 impact event within
the observational uncertainty range. This indicates that the surface color of
dark asteroids is not noticeably changed by space weathering over a 10-year
period. This study is the first to investigate color changes due to space
weathering on an actual asteroid surface in the Solar System. Considering that
fresh layers are regularly created on asteroid surfaces by collisions, we
suggest a genetic link between D/T-type and dark (low albedo) X-complex
asteroids and very red objects such as 269 Justitia, 732 Tjilaki (and 203
Pompeja). New observations show that 203 Pompeja has a X-type-like surface,
with some local surface areas exhibiting a very red spectrum.Comment: 16 pages, 9 figures, 2 tables, Accepted for publication in ApJ
Letter
Evaluation of 17-mm St. Jude Medical Regent prosthetic aortic heart valves by rest and dobutamine stress echocardiography
BACKGROUND: The prosthesis used for aortic valve replacement in patients with small aortic root can be too small in relation to body size, thus showing high transvalvular gradients at rest and/or under stress conditions. This study was carried out to evaluate rest and Dobutamine stress echocardiography (DSE) hemodynamic response of 17-mm St. Jude Medical Regent (SJMR-17 mm) in relatively aged patients at mean 24 months follow-up. METHODS AND RESULTS: The study population consisted of 19 patients (2 men, 17 women, mean age 69.2 ± 7.3 years). All patients underwent rest Doppler echocardiography before and after surgery and basal and DSE at follow up (infused at rate of 5 micrg/Kg/min and increased by 5 microg/Kg/min at 5 min intervals up to 40 microg/Kg/min). The following parameters were evaluated at rest and/or under DSE: heart rate (HR), ejection fraction (EF), cardiac output (CO), peak and mean velocity and pressure gradients (MxV, MnV, MxPG, MnPG), effective orifice area (EOA), indexed EOA (EOAi), left ventricular mass (LVM), indexed LVM (LVMi), Velocity Time Integral at left ventricular outflow tract (VTI LVOT) and transvalvular (Aortic VTI), Doppler velocity index (DVI). At rest MxPG and MnPG were 29.2 ± 7.1 and 16.6 ± 5.8mmHg, respectively; EOA and EOAi resulted 1.14 ± 0.3 cm(2) and 0.76 ± 0.2 cm(2)/m(2); DVI was normal (0.50 ± 0.1). At follow-up LVM and LVMi decreased significantly from pre-operative value of 258 ± 43g and 157.4 ± 27.7g/m(2) to 191 ± 23.8g and 114.5 ± 10.6g/m(2), respectively. DSE increased significantly HR, CO, EF, MxGP (up to 83.4 ± 2 1.9mmHg), MnPG (up to 43.2 ± 12.7mmHg). EOA, EOAi, DVI increased insignificantly (from baseline up to 1.2 ± 0.4 cm(2), 0.75 ± 0.3cm(2)/m(2) and 0.48 ± 0.1 respectively). Two patients developed significant intraventricular gradients. CONCLUSION: These data show that SJMR 17-mm prostheses can be safely implanted in aortic position in relatively aged patients, offering a satisfactory hemodynamic performance at rest and under DSE, with full utilization of its available orifice, suggesting that a possible mild prosthesis-patient mismatch is not an issue of clinical relevance when this small prosthesis is used. Rest and Dobutamine stress echocardiography is a useful and effective means for evaluating prosthesis hemodynamics and for monitoring the expected LVH regression
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