Calogero model with Yukawa like interaction

We study an extension of one dimensional Calogero model involving strongly coupled and electrically charged particles. Besides Calogero term $\frac{g}{2x^{2}}$, there is an extra factor described by a Yukawa like coupling modeling short distance interactions. Mimicking Calogero analysis and using developments in formal series of the wave function $\Psi (x)$ factorised as $x^{\epsilon}\Phi (x)$ with $\epsilon (\epsilon -1) =g$, we develop a technique to approach the spectrum of the generalized system and show that information on full spectrum is captured by $\Phi (x)$ and $\Phi ^{\prime \prime}(x)$ at the singular point $x=0$ of the potential. Convergence of $\int dx| \Psi (x) | ^{2}$ requires $\epsilon >-{1/2}$ and is shown to be sensitive to the zero mode of $\Phi (x)$ at $x=0$. \textbf{Key words}: \textit{Hamitonian systems, quantum integrability, Calogero model, Yukawa like potential.}Comment: 12 pages, 1 figur

Physical properties of highly crystalline CIS layer prepared using single phase electrodeposition and low temperature RTP annealing

CuInSe2 nanoparticles (CIS-NP) were synthesized on ITO-coated glass substrate by electrodeposition and rapid thermal processing (RTP). The as-deposited films were annealed under argon atmosphere at 250 °C, 350 °C and 450 °C using RTP during a short annealing time. The latter is practicable to avoid further losing of the Se content in CIS films. In order to analyze the effect of annealing temperature, the structural, morphological, optical and electrical properties were investigated by means of X-ray diffraction, scanning electron microscopy, UV–Visible Spectroscopy and Mott-Schottky plots respectively. XRD results show that elaborated films have a tetragonal chalcopyrite CIS with preferential orientation along the (112) orientation. The phase formation of CIS-NP with good crystallinity was observed at low annealing temperature. Optical absorption studies indicate a direct band gap around 1.02 eV at 250 °C. The optical constants such as refractive index n(λ) and extinction coefficient k(λ) were estimated using an appropriate optical model. To determine the doping type of elaborated semiconductor, its flat band potential and the free carrier concentration we used the Mott-Schottky plots. A new attempt to anneal the electrodeposited CIS films by short annealing duration using RTP process was proved to be a useful method to synthesize polycrystalline CIS films for solar cell application

CONSOMMATEUR CONSCIENTISE : SON IMPACT SUR LES CHAINES LOGISTIQUES DURABLES

De nos jours, le consommateur joue un rôle crucial dans la création des chaînes logistiques. Faisant partie de la plupart des entreprises et étant essentiel à leur succès. Il a le pouvoir de bouleverser les marchés et de changer les tendances. Il participe à la chaîne de valeur depuis le début en passant par la conception du produit, jusqu’à la fin via la logistique inverse et le recyclage. Ces dernières décennies les exigences du consommateur ont connu une augmentation significative, et le besoin d’unicité est devenu un choix par défaut. Le comportement des consommateurs se développe, ce qui contribue à la complexité du contrôle de la chaîne logistique. Les chaînes logistiques doivent être suffisamment résilientes et agiles pour faire face à l'incertitude du marché et satisfaire les besoins consommateurs. En outre, le consommateur est de plus en plus conscient de l'importance du respect de durabilité et est devenu un élément essentiel de la chaîne logistique. Ce travail étudie le comportement d’un consommateur conscientisé et la manière dont elle influence les chaînes logistiques et leur durabilité. Un cadre conceptuel est élaboré qui donne une idée sur la relation d'influence entre les variables. Enfin, des perspectives d'avenir sont fournies pour orienter les recherches à veni

Insight into biological activities of chemically characterized extract from Marrubium vulgare L. in vitro, in vivo and in silico approaches

Aqueous extracts of Marrubium vulgare L. (M. vulgare) are widely used in traditional medicine for their therapeutic effects. Hence, this study aims to evaluate in vitro, in vivo, and in silico the biological activities of M. vulgare aqueous extract to further support their traditional use. Qualitative phytochemical tests of M. vulgare extracts showed the presence of primary and secondary metabolites, while quantitative analyses recorded revealed the contents of total phenols, flavonoids, and tannins, with values of 488.432 ± 7.825 mg/EAG gallic acid extract/g, 25.5326 ± 1.317 mg/EQ Quercetin extract/g and 23.966 ± 0.187 mg/EC catechin extract/g, respectively. Characterization of the phytochemical constituents of the extract revealed the presence of catechin and maleic acid as the most abundant while the evaluation of the antioxidant power revealed that the extract possesses significant antioxidant capacity, antimitotic potential, and antimicrobial properties against Streptococcus agalactiae and Staphylococcus epidermidis among many others. The antidiabetic activity of the extract showed a potent antihyperglycemic effect and a significant modulation of the pancreatic α-amylase activity as revealed by both in vitro and in vivo analysis, while an in silico evaluation showed that chemicals in the studied extract exhibited the aforementioned activities by targeting 1XO2 antimitotic protein, W93 antidiabetic protein and 1AJ6 antimicrobial protein, which revealed them as worthy of exploration in drug discovery odyssey. Conclusively, the result of this study demonstrates the numerous biological activities of M. vulgare and gives credence to their folkloric and traditional usage

Electrochemical, spectroscopic and molecular docking studies of 4-methyl-5-((phenylimino)methyl)-3H- and 5-(4-fluorophenyl)-3H-1,2-dithiole-3-thione interacting with DNA

<p>Cyclic voltammetry (CV) and UV–Visible spectroscopy (UV–Vis) techniques were used to calculate binding parameters of 4-methyl-5-((phenylimino)methyl)-3H-1,2-dithiole-3-thione (MPDT) and 5-(4-fluorophenyl)-3H-1,2-dithiole-3-thione (FPDT) with DNA. The results obtained from both techniques were confirmed by computational molecular docking using AutoDock molecular docking software. The anodic peak potential shift in CV indicated an intercalative mode of binding. The binding constants (M⁻¹) of the adducts MPDT-DNA and FPDT-DNA obtained from voltammetric measurements were found to be 8.0 × 10⁴ and 2.4 × 10⁴, respectively, with binding free energy being −27.99 and −25.01 KJ mol⁻¹, respectively. These results are in good agreement with those obtained from UV–Visible spectroscopic studies. The diffusion coefficients of MPDT and FPDT (2.06 × 10⁻¹⁰ and 2.42 × 10⁻⁹, respectively) were found to be higher than those of DNA-bound compounds (1.27 × 10⁻¹⁰ and 1.65 × 10⁻⁹ cm²/s, respectively). The binding free energy of MPDT and FPDT to DNA was also calculated by molecular docking study. The docking study gave excellent approximation with experimental results, shedding light on the sites of binding.</p

Preventive effects of royal jelly against anaphylactic response in a murine model of cow’s milk allergy

Context: Royal jelly (RJ) has long been used to promote human health. Objective: The current study investigated the preventive effects of RJ against the development of a systemic and intestinal immune response in mice allergic to cow’s milk proteins. Materials and methods: Balb/c mice treated orally for seven days with RJ at doses of 0.5, 1 and 1.5 g/kg were sensitized intraperitoneally with β-lactoglobulin (β-Lg). Serum IgG and IgE anti-β-Lg were determined by an enzyme-linked immunosorbent assay (ELISA). Plasma histamine levels, symptom scores and body temperature were determined after in vivo challenge to β-Lg. Jejunums were used for assessment of local anaphylactic responses by an ex vivo study in Ussing chambers and morphologic changes by histological analysis. Results: RJ significantly decreased serum IgG (31.15–43.78%) and IgE (64.28–66.6%) anti-β-Lg and effectively reduced plasma histamine level (66.62–67.36%) (p < 0.001) at all the doses tested. Additionally, no clinical symptoms or body temperature drops were observed in RJ-pretreated mice. Interestingly, RJ significantly reduced (p < 0.001) intestinal dysfunction by abolishing the secretory response (70.73–72.23%) induced by sensitization and prevented length aberrations of jejunal villi by 44.32–59.01% (p < 0.001). Discussion and conclusions: We speculate that using RJ may help prevent systemic and anaphylactic response in allergic mice. These effects may be related to its inhibitory effects on the degranulation of mast cells

SYMBIOTIC ENHANCES GUT MUCOSA RECOVERY RATE AND REDUCES OVERGROWTH OF BACTERIA IN EXPERIMENTAL PROTEIN MALNUTRITION

Objective: Investigate the effect of symbiotic on the recovery of bowel atrophy and bacterial translocation (BT) induced by protein malnutrition (PM) in rats.Methods: Rats were fed protein-deficient diet (maize) or the standard diet (standard rat chow) for 15 days. On day 10, rats fed with the protein-deficient diet were subdivided into three groups for reconstitution with protein-rich diet and Symbiotic. Milk-MTZ group, received milk+Metronidazole for 5 days and Symbiotic group, fed with some diet and probiotics-oligofructosaccharide for 5 days. Body weight was monitored daily, and all animals were sacrificed on day 15, and intestinal microflora and bacterial translocation (BT) to mesenteric lymph nodes (MLN) were evaluated. Histological studies were carried out to evaluate villi length and intra epithelial lymphocyte (IEL) infiltration.Results: Our results show the symbiotic group (n=6) having the greater gain in body weight (12% increase) than milk-MTZ-fed group (n=6, 0.61 % increase). Overgrowth of Enterobacteria in protein-deficient diet rats was higher than in controls (p&lt;0.0001); whereas, significantly decreasing in symbiotic fed group (p&lt;0.0001). There was no significant difference in bacterial translocation between rats fed protein-deficient diet and those fed symbiotic rich diet. However, gut mucosa recovery was greater in symbiotic group (49.24 %).Conclusion: Our data suggests that symbiotic-rich diet induces an important gain in weight and leads to better recovery of gut mucosa, but without altering bacterial translocation rate induced by the protein-deficient diet.Â