1,197 research outputs found
A survey of New Hampshire sewage sludges as related to their suitability for on-land disposal, Station Bulletin, no.503
The Bulletin is a publication of the New Hampshire Agricultural Experiment Station, College of Life Sciences and Agriculture, University of New Hampshire, Durham, New Hampshire
Growing house plants, Bulletin, no. 359
The Bulletin is a publication of the New Hampshire Agricultural Experiment Station, College of Life Sciences and Agriculture, University of New Hampshire, Durham, New Hampshire
Balancing problems of independent milk dealers operating small and medium size plants, Station Bulletin, no.460
The Bulletin is a publication of the New Hampshire Agricultural Experiment Station, College of Life Sciences and Agriculture, University of New Hampshire, Durham, New Hampshire
Karak syndrome: a novel degenerative disorder of the basal ganglia and cerebellum
Two brothers are reported with early onset progressive
cerebellar ataxia, dystonia, spasticity, and intellectual
decline.
• Neuroradiology showed cerebellar atrophy and features
compatible with iron deposition in the putamen
(including the “eye of the tiger sign”) and substantia
nigra.
• Diagnosis was compatible with pantothenate kinase
associated neuropathy resulting from pantothenate
kinase 2 mutation (PKAN due to PANK2) but linkage to
PNAK2 was eliminated suggesting Karak syndrome to
be a novel disorder.
• The “eye of the tiger” sign has previously only been
reported to occur in PKAN due to PKAN
Adaptive working memory strategy training in early Alzheimer's disease: randomised controlled trial.
BACKGROUND: Interventions that improve cognitive function in Alzheimer's disease are urgently required. AIMS: To assess whether a novel cognitive training paradigm based on 'chunking' improves working memory and general cognitive function, and is associated with reorganisation of functional activity in prefrontal and parietal cortices (trial registration: ISRCTN43007027).
METHOD: Thirty patients with mild Alzheimer's disease were randomly allocated to receive 18 sessions of 30 min of either adaptive chunking training or an active control intervention over approximately 8 weeks. Pre- and post-intervention functional magnetic resonance imaging (fMRI) scans were also conducted.
RESULTS: Adaptive chunking training led to significant improvements in verbal working memory and untrained clinical measures of general cognitive function. Further, fMRI revealed a bilateral reduction in task-related lateral prefrontal and parietal cortex activation in the training group compared with controls.
CONCLUSIONS: Chunking-based cognitive training is a simple and potentially scalable intervention to improve cognitive function in early Alzheimer's disease
The importance of sustained attention in early Alzheimer's disease
INTRODUCTION: There is conflicting evidence regarding impairment of sustained attention in early Alzheimer's disease (AD). We examine whether sustained attention is impaired and predicts deficits in other cognitive domains in early AD. METHODS: Fifty-one patients with early AD (MMSE > 18) and 15 healthy elderly controls were recruited. The sustained attention to response task (SART) was used to assess sustained attention. A subset of 25 patients also performed tasks assessing general cognitive function (ADAS-Cog), episodic memory (Logical memory scale, Paired Associates Learning), executive function (verbal fluency, grammatical reasoning) and working memory (digit and spatial span). RESULTS: AD patients were significantly impaired on the SART compared to healthy controls (total error β = 19.75, p = 0.027). SART errors significantly correlated with MMSE score (Spearman's rho = -0.338, p = 0.015) and significantly predicted deficits in ADAS-Cog (β = 0.14, p = 0.004). DISCUSSIONS: Patients with early AD have significant deficits in sustained attention, as measured using the SART. This may impair performance on general cognitive testing, and therefore should be taken into account during clinical assessment, and everyday management of individuals with early AD
Modelling and comparison of in-field critical current density anisotropy in high temperature superconducting (HTS) coated conductors
The development of high-temperature superconducting (HTS) wires is now at a stage where long lengths of high quality are commercially available, and of these, (Re)BCO coated conductors show the most promise for practical applications. One of the most crucial aspects of coil and device modeling is providing accurate data for the anisotropy of the critical current density Jc(B, θ) of the superconductor. In this paper, the in-field critical current density characteristics Jc(B, θ) of two commercial HTS coated conductor samples are experimentally measured, and based on these data, an engineering formula is introduced to represent this electromagnetic behavior as the input data for numerical modeling. However, due to the complex nature of this behavior and the large number of variables involved, the computational speed of the model can be extremely slow. Therefore, a two-variable direct interpolation method is introduced, which completely avoids any complex data fitting for Jc(B, θ) and expresses the anisotropic behavior in the model directly and accurately with a significant improvement in computational speed. The two techniques are validated and compared using numerical models based on the H-formulation by calculating the self-field and in-field dc critical currents and the ac loss for a single coated conductor
Growth and feed standards for broilers -- 1973, Station Bulletin, no.502
The Bulletin is a publication of the New Hampshire Agricultural Experiment Station, College of Life Sciences and Agriculture, University of New Hampshire, Durham, New Hampshire
Economic study of New Hampshire poultry farms, Bulletin, no. 265
The Bulletin is a publication of the New Hampshire Agricultural Experiment Station, College of Life Sciences and Agriculture, University of New Hampshire, Durham, New Hampshire
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