336 research outputs found

    Dark matter and sub-GeV hidden U(1) in GMSB models

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    Motivated by the recent PAMELA and ATIC data, one is led to a scenario with heavy vector-like dark matter in association with a hidden U(1)XU(1)_X sector below GeV scale. Realizing this idea in the context of gauge mediated supersymmetry breaking (GMSB), a heavy scalar component charged under U(1)XU(1)_X is found to be a good dark matter candidate which can be searched for direct scattering mediated by the Higgs boson and/or by the hidden gauge boson. The latter turns out to put a stringent bound on the kinetic mixing parameter between U(1)XU(1)_X and U(1)YU(1)_Y: θ106\theta \lesssim 10^{-6}. For the typical range of model parameters, we find that the decay rates of the ordinary lightest neutralino into hidden gauge boson/gaugino and photon/gravitino are comparable, and the former decay mode leaves displaced vertices of lepton pairs and missing energy with distinctive length scale larger than 20 cm for invariant lepton pair mass below 0.5 GeV. An unsatisfactory aspect of our model is that the Sommerfeld effect cannot raise the galactic dark matter annihilation by more than 60 times for the dark matter mass below TeV.Comment: 1+15 pages, 4 figures, version published in JCAP, references added, minor change

    On the massless "just-so" solution to the solar neutrino problem

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    We study the effect of the non-resonant, vacuum oscillation-like neutrino flavor conversion induced by non-standard flavor changing and non-universal flavor diagonal neutrino interactions with electrons in the sun. We have found an acceptable fit for the combined analysis for the solar experiments total rates, the Super-Kamiokande (SK) energy spectrum and zenith angle dependence. Phenomenological constraints on non-standard flavor changing and non-universal flavor diagonal neutrino interactions are considered.Comment: 4 pages, Latex, uses eps

    Does Culture Impact Preferred Employee attributes in Complaint Handling Encounters?

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    Recently, Gruber et al.’s (2011) Kano study revealed that complaining customers in Saudi Arabia are less difficult to delight than UK customers. The present study investigates whether these differences are caused by different service sector development stages, as suggested in their study, or by cultural differences instead. Data were collected using Kano questionnaires from 151 respondents with complaining experience in Singapore. This country was chosen as it has a highly developed service economy (like the UK) but also a collectivistic culture (like Saudi Arabia). The analysis reveals that Singaporean customers show the same preferences as those in the UK. We consider this as a strong indicator for the suggested impact of the stage of service sector development rather than cultural differences on complaining customers’ preferences of frontline employee attributes. Our results support the findings by Gruber et al. (2011). By doing so, they surprisingly refute previous research which concluded that national culture plays a significant role in shaping customer expectations during complaint handling encounters. Our study especially corroborates the notion of a life cycle of quality attributes that had been found for goods and services and the preferred attributes of frontline employees dealing with customer complaints

    Cross Section Measurements of Charged Pion Photoproduction in Hydrogen and Deuterium from 1.1 to 5.5 GeV

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    The differential cross section for the gamma +n --> pi- + p and the gamma + p --> pi+ n processes were measured at Jefferson Lab. The photon energies ranged from 1.1 to 5.5 GeV, corresponding to center-of-mass energies from 1.7 to 3.4 GeV. The pion center-of-mass angles varied from 50 degree to 110 degree. The pi- and pi+ photoproduction data both exhibit a global scaling behavior at high energies and high transverse momenta, consistent with the constituent counting rule prediction and the existing pi+ data. The data suggest possible substructure of the scaling behavior, which might be oscillations around the scaling value. The data show an enhancement in the scaled cross section at center-of-mass energy near 2.2 GeV. The differential cross section ratios at high energies and high transverse momenta can be described by calculations based on one-hard-gluon-exchange diagrams.Comment: 18 pages, 19 figure

    Enhancing clinical decision support with genomic tools in breast cancer: a Scottish perspective

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    Introduction: The Oncotype DX Breast RS test has been adopted in Scotland and has been the subject of a large population-based study by a Scottish Consensus Group to assess the uptake of the recurrence score (RS), evaluate co-variates associated with the RS and to analyse the effect it may have had on clinical practice. Materials & Methods: Pan-Scotland study between August 2018–August 2021 evaluating 833 patients who had a RS test performed as part of their diagnostic pathway. Data was extracted retrospectively from electronic records and analysis conducted to describe change in chemotherapy administration (by direct comparison with conventional risk assessment tools), and univariate/multivariate analysis to assess relationship between covariates and the RS. Results: Chemotherapy treatment was strongly influenced by the RS (p < 0.001). Only 30 % of patients received chemotherapy treatment in the intermediate and high risk PREDICT groups, where chemotherapy is considered. Additionally, 55.5 % of patients with a high risk PREDICT had a low RS and did not receive chemotherapy. There were 17 % of patients with a low risk PREDICT but high RS who received chemotherapy. Multivariate regression analysis showed the progesterone receptor Allred score (PR score) to be a strong independent predictor of the RS, with a negative PR score being associated with high RS (OR 4.49, p < 0.001). Increasing grade was also associated with high RS (OR 3.81, p < 0.001). Classic lobular pathology was associated with a low RS in comparison to other tumour pathology (p < 0.01). Nodal disease was associated with a lower RS (p = 0.012) on univariate analysis, with menopausal status (p = 0.43) not influencing the RS on univariate or multivariate analysis. Conclusions: Genomic assays offer the potential for risk-stratified decision making regarding the use of chemotherapy. They can help reduce unnecessary chemotherapy treatment and identify a subgroup of patients with more adverse genomic tumour biology. A recent publication by Health Improvement Scotland (HIS) has updated guidance on use of the RS test for NHS Scotland [1].It suggests to limit its use to the intermediate risk PREDICT group. Our study shows the impact of the RS test in the low and high risk PREDICT groups. The implementation across Scotland has resulted in a notable shift in practice, leading to a significant reduction in chemotherapy administration in the setting of high risk PREDICT scores returning low risk RS. There has also been utility for the test in the low risk PREDICT group to detect a small subgroup with a high RS. We have found the PR score to have a strong independent association with high risk RS. This finding was not evaluated by the key RS test papers, and the potential prognostic information provided by the PR score as a surrogate biomarker is an outstanding question that requires more research to validate

    Tight-binding parameters for charge transfer along DNA

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    We systematically examine all the tight-binding parameters pertinent to charge transfer along DNA. The π\pi molecular structure of the four DNA bases (adenine, thymine, cytosine, and guanine) is investigated by using the linear combination of atomic orbitals method with a recently introduced parametrization. The HOMO and LUMO wavefunctions and energies of DNA bases are discussed and then used for calculating the corresponding wavefunctions of the two B-DNA base-pairs (adenine-thymine and guanine-cytosine). The obtained HOMO and LUMO energies of the bases are in good agreement with available experimental values. Our results are then used for estimating the complete set of charge transfer parameters between neighboring bases and also between successive base-pairs, considering all possible combinations between them, for both electrons and holes. The calculated microscopic quantities can be used in mesoscopic theoretical models of electron or hole transfer along the DNA double helix, as they provide the necessary parameters for a tight-binding phenomenological description based on the π\pi molecular overlap. We find that usually the hopping parameters for holes are higher in magnitude compared to the ones for electrons, which probably indicates that hole transport along DNA is more favorable than electron transport. Our findings are also compared with existing calculations from first principles.Comment: 15 pages, 3 figures, 7 table

    Recoil Polarization for Delta Excitation in Pion Electroproduction

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    We measured angular distributions of recoil-polarization response functions for neutral pion electroproduction for W=1.23 GeV at Q^2=1.0 (GeV/c)^2, obtaining 14 separated response functions plus 2 Rosenbluth combinations; of these, 12 have been observed for the first time. Dynamical models do not describe quantities governed by imaginary parts of interference products well, indicating the need for adjusting magnitudes and phases for nonresonant amplitudes. We performed a nearly model-independent multipole analysis and obtained values for Re(S1+/M1+)=-(6.84+/-0.15)% and Re(E1+/M1+)=-(2.91+/-0.19)% that are distinctly different from those from the traditional Legendre analysis based upon M1+ dominance and sp truncation.Comment: 5 pages, 2 figures, for PR

    The supersymmetric prediction for the muon transverse polarization in the K+π0μ+νμK^+ \leftarrow \pi^0 \mu^+ \nu_\mu decay

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    The muon transverse polarization in the K+π0μ+νμK^+ \leftarrow \pi^0 \mu^+ \nu_\mu decay will be measured at the 10410^{-4} level in forthcoming experiments. We compare the phenomenological perspectives with the theoretical predictions in supersymmetric extensions of the standard model. In the minimal extension, CP-violating phases lead to a non-zero transverse polarization, that however is too small to account for a positive experimental signal. The problems that one encounters when departing from minimal assumptions are discussed. An observable effect is possible if the hypothesis of R-parity conservation is relaxed, but only at the price of assuming a very special pattern for the R-parity breaking couplings.Comment: latex, 18 pages, 1 latex figur

    Charm multiplicity and the branching ratios of inclusive charmless b quark decays in the general two-Higgs-doublet models

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    In the framework of general two-Higgs-doublet models, we calculate the branching ratios of various inclusive charmless b decays by using the low energy effective Hamiltonian including next-to-leading order QCD corrections, and examine the current status and the new physics effects on the determination of the charm multiplicity ncn_c and semileptonic branching ratio BSLB_{SL}. Within the considered parameter space, the enhancement to the ratio BR(bsg)BR(b \to s g) due to the charged-Higgs penguins can be as large as a factor of 8 (3) in the model III (II), while the ratio BR(bnocharm)BR(b \to no charm) can be increased from the standard model prediction of 2.49% to 4.91% (2.99%) in the model III (II). Consequently, the value of BSLB_{SL} and ncn_c can be decreased simultaneously in the model III. The central value of BSLB_{SL} will be lowered slightly by about 0.003, but the ratio ncn_c can be reduced significantly from the theoretical prediction of nc=1.28±0.05n_c= 1.28 \pm 0.05 in the SM to nc=1.23±0.05n_c= 1.23 \pm 0.05, 1.18±0.051.18 \pm 0.05 for mH+=200,100m_{H^+}=200, 100 GeV, respectively. We find that the predicted ncn_c and the measured ncn_c now agree within roughly one standard deviation after taking into account the effects of gluonic charged Higgs penguins in the model III with a relatively light charged Higgs boson.Comment: 25 pages, Latex file, axodraw.sty, 6 figures. Final version to be published in Phys.Rev.
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