Evaluation of depression and anxiety in patients with thalassemia: a comparative study

Background: More studies in the field of thalassemia patients focus on medical treatment and less attention to the psychosocial problems aspect. Objective: The aim of this study was evaluation of depression and anxiety in these patients in Qazvin province. Methods: This case-control study has been conducted in Qods Hospital of Qazvin (2016). The study population included thalassemia major patients and control group were participating in this study (n=147 in each group). All subjects completed the hospital anxiety and depression scale (HADS). In addition to clinical history, socioeconomic and demographic characteristics of patients collected and analyzed using proper statistical methods independent t-test, chi-square test. Findings: Borderline abnormal (borderline case) and abnormal states of anxiety were reported 27.2% and 42.2% in case group compared with 22.4% and 6.8% in the control group (P<0.001). In addition, borderline and abnormal states of depression were significantly different in the case group than the control group (respectively 20.4% and 59.2% vs 24.5% and 12.9%, P<0.001). Among patients with thalassemia, depression and anxiety scores significantly were associated with noncompliance and iron chelation, marital status (single) and socioeconomic state (P<0.001). In addition, Moreover, in terms of depression individuals with diabetes, headaches and skin disorders significantly were higher scores of depression and in terms of anxiety individuals with low back pain, headaches and skin disorders were higher scores. Conclusion: The prevalence of depression and anxiety in patients with thalassemia is considerable and related to socioeconomic and demographic characteristics, so it is essential that psychiatric consultation systems created in thalassemia clinics of Qazvin province

Effectiveness of Stress Management With Cognitive-Behavioral Approach on Cognitive Emotion Regulation in Mothers of Children With Cancer

Background: The purpose of this study was to determine the effectiveness of stress management therapy with a cognitive-behavioral approach to cognitive emotion regulation in mothers of children with cancer.Methods: The research method was quasi-experimental with pre-test, post-test, and follow up design as well as the control group. The statistical population of this study included all mothers of children with cancer who referred to the Qods children’s hospital located in Qazvin province. A sample of 30 subjects was selected through purposive sampling and assigned to two groups of experimental (n = 15) and control (n = 15). Both groups were pre-tested using the Cognitive Emotion Regulation Questionnaire (CERQ). Then, the experimental group received 8 sessions of training in stress management skills with cognitive-behavioral approach while the control group did not receive any intervention. Subsequently, both groups administered post-test, and the data were analyzed by SPSS 21 software using single variable one-way ANOVA.Results: The results showed improvement in the scores of the experimental group mothers in cognitive emotion regulation variable and components of self-blame, acceptance, rumination, positive refocusing, refocus on planning, perspective-taking, catastrophization, and other-blame. However, no significant improvement observed in the component of positive reappraisal in parents of children with cancer (P &lt; 0.01) and this maintained at the follow-up stage.Conclusion: Based on the findings of this study it can be concluded that teaching stress coping strategies with a cognitive-behavioral approach is an effective way to teach emotion regulation strategies to mothers of children with cancer suffering from emotional distress

Effectiveness of Stress Management with Cognitive-Behavioral Approach on Anxiety Sensitivity of the Mothers with Cancerous Children

Background and Purpose: Cancer is considered as one of the most radical hygienic issues in children. It threats the health and active lives of children and their parents causing numerous personal, familiar and social damages in physical, mental and social dimensions. This study aimed to investigate the effectiveness of stress management with cognitive-behavioral approach on the anxiety sensitivity of the mothers with cancerous children.Methods: In a quasi-experimental with pretest- posttest study, 30 mothers with cancerous children were selected using purposeful sampling and divided into case and control groups. Both groups were given pretest using the 16 questions questionnaire of anxiety sensitivity. Then, the skills of stress management with cognitive-behavioral approach were taught to the case group for 8 sessions and the control group didn’t receive any intervention. Finally both groups were given posttest and the data were analyzed using one-way and single variable variance analysis through SPSS21 software.Results: Mothers in case group showed reduction in the anxiety compared to the control one and it was maintained in the following period (p &lt; 0.01). The highest reduction was in the parameter of the fear of physical concerns (p &lt; 0.01).Conclusion: Teaching the methods of coping with stress with cognitive-behavioral approach is an effective strategy for helping mothers with cancerous children due to its high efficiency especially when it is held in groups

The influence of freezing conditions on the organoleptic attributes of Iranian leafy vegetable foods

The edible leafy vegetables contain nutritional ingredients that are necessary for human health and it is important that nutrients protection be monitored during processing and storage. The aim of this study was to study some organoleptic attributes of a very popular Iranian meal named Coco-Sabzi, which was prepared with a mixture of edible grinded leafy vegetable pre-stored at different frozen conditions. So, by sensorial evaluation we can conclude about nutritional loss of products. The mixture of five edible grinded leafy vegetables including Allium ampeloprasum var. porrum, Lepidium sativum, M. spicata (M. sativa), Ocimum basilicum and Allium porrum were stored at -9, -12 and -18oC for 120, 150 and 180 days. The organoleptic attribute of the prepared Coco-Sabzi was compared with the above three different time-temperature combinations during the frozen storage period. Results indicated that the best colors were observed at -18, -12 and -9oC, respectively. Taste and overall acceptability at -18oC after 120 and 150 days and also at -12oC after 180 days ranked 1st (P&lt; 0.05). Data analysis showed that the color, taste and overall acceptability of samples were not statistically different at three different time-temperature combinations during the frozen storage period. As a result, organoleptic attribute during six months of frozen storage was affected by freezing temperature, not by frozen storage perio

Comparison of Effectiveness of the Mindfulness-Based Cognitive Therapy and the Metacognition Treatment on Anxiety, Depression and Stress Among Breast Cancer Patients

Background: The present study aimed to compare the effectiveness the metacognition treatment (MCT) and mindfulness-based cognitive therapy (MBCT) on anxiety, depression, and stress in the females with breast cancer.Methods: The planning of this study is through a quasi-experimental method of pretest and posttest type with control group. The target society of the research included every cancer patient who admitted to Tehran hospitals for breast cancer. Through assigned randomly, 12 patients were selected for the MCT group and 12 patients for the MBCT group, and the other were assigned control group. The data collection tools included depression, anxiety and stress scale - 21 items (DASS-21) questionnaire. For statistical analysis, descriptive tests and repeated measures analysis of variance were performed.Results: Data analysis with repeated multivariate measurements illustrated that there is a significant difference in the rate of depression, anxiety and stress, in three groups.Conclusion: According to our results, MBCT was more effective compared to metacognitive therapy

Examining the Effectiveness of Mindfulness-Based Cognitive Therapy on Quality of Life in primary Infertile Women

The present study aimed to examine the effectiveness of mindfulness-based cognitive therapy on quality of life in infertile women. Semi-experimental design, a randomized controlled trial with assessment in baseline, after intervention and two- month follow-up was conducted on participants of control group. A total of 24 female patients with primary infertility diagnosis among patients who referred to the Infertility Center of Shariati hospital in Tehran were selected as volunteers and were assigned randomly into the experimental (n=12) and control groups (n=12). All participants completed Infertile Couples’ Quality of Life Questionnaire in three phases of baseline, after treatment and follow-up. Data were analyzed using multivariate repeated measurement of variance analysis. Results showed that mindfulness-based cognitive therapy improve the quality of life in social and psychological components, depression, aggression and jealousy in participants of experimental group. Results of this study showed that mindfulness - based cognitive therapy can be effective in improving quality of life in infertile women

Examining the Effectiveness of Mindfulness-Based Cognitive Therapy on Quality of Life in primary Infertile Women

The present study aimed to examine the effectiveness of mindfulness-based cognitive therapy on quality of life in infertile women. Semi-experimental design, a randomized controlled trial with assessment in baseline, after intervention and two- month follow-up was conducted on participants of control group. A total of 24 female patients with primary infertility diagnosis among patients who referred to the Infertility Center of Shariati hospital in Tehran were selected as volunteers and were assigned randomly into the experimental (n=12) and control groups (n=12). All participants completed Infertile Couples’ Quality of Life Questionnaire in three phases of baseline, after treatment and follow-up. Data were analyzed using multivariate repeated measurement of variance analysis. Results showed that mindfulness-based cognitive therapy improve the quality of life in social and psychological components, depression, aggression and jealousy in participants of experimental group. Results of this study showed that mindfulness - based cognitive therapy can be effective in improving quality of life in infertile women

Comparison of the Effectiveness of Mindfulness-Based Stress Reduction Group Therapy With Acceptance and Commitment Therapy on Severity of Pain and Health-Related Quality of Life in Patients With Migraine

Objective: Considering the prevalence of migraine and its detrimental effects on functioning, physical health, and quality of life as well as its psychosocial and social risks, the purpose of this study was to compare the effectiveness of mindfulness-based stress reduction treatment with treatment based on acceptance and commitment on the severity of pain and health-related quality of life in migraine patients.Methodology: In this study, a semi-experimental design was used with pre-test, post-test, a three-month follow-up, and a control group. Using purposive sampling and considering the inclusion criteria, 45 patients with migraine diagnosis were selected from among those referring to the neurology department of Imam Hossein Hospital in Tehran. They were then randomly assigned to two experimental groups and a control group. The first experimental group received group therapy based on mindfulness (n = 15; 90-minute sessions), the second experimental group received acceptance and commitment based intervention (n = 15; 90-minute sessions), and the control group (n = 15) received no intervention. All subjects responded to pain intensity and health-related quality of life questionnaires before the intervention (pre-test), after the intervention (post-test), and 3 months after the intervention (follow-up). Collected data were analyzed by one-way ANOVA.Findings: The findings showed that mean scores for the two experimental groups were significantly different from the control group in the post-test and follow-up phases in terms of severity of pain and health-related quality of life, while the mean scores for the two experimental groups did not differ significantly. The results emphasize the importance of these interventions for chronic diseases and offer new horizons in clinical interventions.Conclusion: The results of this study showed that mindfulness-based stress reduction therapy and acceptance and commitment therapy can positively affect the severity of pain and health-related quality of life in migraine patients, and any of them can be used to improve the above-mentioned variables

Description of combined ARHSP/JALS phenotype in some patients with SPG11 mutations

Background: SPG11 mutations can cause autosomal recessive hereditary spastic paraplegia (ARHSP) and juvenile amyotrophic lateral sclerosis (JALS). Because these diseases share some clinical presentations and both can be caused by SPG11 mutations, it was considered that definitive diagnosis may not be straight forward. Methods: The DNAs of referred ARHSP and JALS patients were exome sequenced. Clinical data of patients with SPG11 mutations were gathered by interviews and neurological examinations including electrodiagnosis (EDX) and magnetic resonance imaging (MRI). Results: Eight probands with SPG11 mutations were identified. Two mutations are novel. Among seven Iranian probands, six carried the p.Glu1026Argfs*4-causing mutation. All eight patients had features known to be present in both ARHSP and JALS. Additionally and surprisingly, presence of both thin corpus callosum (TCC) on MRI and motor neuronopathy were also observed in seven patients. These presentations are, respectively, key suggestive features of ARHSP and JALS. Conclusion: We suggest that rather than ARHSP or JALS, combined ARHSP/JALS is the appropriate description of seven patients studied. Criteria for ARHSP, JALS, and combined ARHSP/JALS designations among patients with SPG11 mutations are suggested. The importance of performing both EDX and MRI is emphasized. Initial screening for p.Glu1026Argfs*4 may facilitate SPG11 screenings in Iranian patients. © 2020 The Authors. Molecular Genetics & Genomic Medicine published by Wiley Periodicals LL

Behavioral Modification of Parents With the Barkley Method to Increase Resilience of Mothers of Children With Attention Deficit/Hyperactivity Disorder

Background: Mothers of children with attention deficit/hyperactivity disorder are faced with more stress than mothers of healthy children and this extreme stress can affect their ability to train their children effectively. Psychologists believe that there is a moderating factor between stressful events and psychological disorders that cause stressful events to have different effects on individuals. A type of this moderating factor is resiliency. Objectives: To determine the efficacy of behavioral modification with Barkley method on resilience of mothers of children with attention deficit/hyperactivity disorder (ADHD). Patients and Methods: Twenty-four mothers of children diagnosed with ADHD were randomly enrolled in this study. The mothers were selected from the 22nd of Bahman hospital of Qazvin city. Mothers with a low score in resilience with children aged between four and twelve years were assigned to experimental and control groups. In this study, a questionnaire was used to measure resilience. The data were analyzed by covariance analysis. Results: The behavioral modification of mothers with the Barkley method significantly enhanced their resiliency with children of ADHD in the experimental group compared to the control group. Conclusions: The behavioral modification was found to be effective for the resilience of mothers of children with ADHD. Keywords: Attention Deficit/Hyperactivity Disorder (ADHD); Resilience; Behavioral Modificatio