66 research outputs found

    HeyTAP: Bridging the Gaps Between Users' Needs and Technology in IF-THEN Rules via Conversation

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    In the Internet of Things era, users are willing to personalize the joint behavior of their connected entities, i.e., smart devices and online service, by means of IF-THEN rules. Unfortunately, how to make such a personalization effective and appreciated is still largely unknown. On the one hand, contemporary platforms to compose IF-THEN rules adopt representation models that strongly depend on the exploited technologies, thus making end-user personalization a complex task. On the other hand, the usage of technology-independent rules envisioned by recent studies opens up new questions, and the identification of available connected entities able to execute abstract users' needs become crucial. To this end, we present HeyTAP, a conversational and semantic-powered trigger-action programming platform able to map abstract users' needs to executable IF-THEN rules. By interacting with a conversational agent, the user communicates her personalization intentions and preferences. User's inputs, along with contextual and semantic information related to the available connected entities, are then used to recommend a set of IF-THEN rules that satisfies the user's needs. An exploratory study on 8 end users preliminary confirms the effectiveness and the appreciation of the approach, and shows that HeyTAP can successfully guide users from their needs to specific rules

    Understanding the faint red galaxy population using large-scale clustering measurements from SDSS DR7

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    We use data from the SDSS to investigate the evolution of the large-scale galaxy bias as a function of luminosity for red galaxies. We carefully consider correlation functions of galaxies selected from both photometric and spectroscopic data, and cross-correlations between them, to obtain multiple measurements of the large-scale bias. We find, for our most robust analyses, a strong increase in bias with luminosity for the most luminous galaxies, an intermediate regime where bias does not evolve strongly over a range of two magnitudes in galaxy luminosity, and no evidence for an upturn in bias for fainter red galaxies. Previous work has found an increase in bias to low luminosities that has been widely interpreted as being caused by a strong preference for red dwarf galaxies to be satellites in the most massive halos. We can recover such an upturn in bias to faint luminosities if we push our measurements to small scales, and include galaxy clustering measurements along the line-of-sight, where we expect non-linear effects to be the strongest. The results that we expect to be most robust suggest that the low luminosity population of red galaxies is not dominated by satellite galaxies occupying the most massive haloes.Comment: Matches version accepted by MNRA

    Juvenile king scallop, Pecten maximus, is potentially tolerant to low levels of ocean acidification when food is unrestricted.

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    The decline in ocean water pH and changes in carbonate saturation states through anthropogenically mediated increases in atmospheric CO2 levels may pose a hazard to marine organisms. This may be particularly acute for those species reliant on calcareous structures like shells and exoskeletons. This is of particular concern in the case of valuable commercially exploited species such as the king scallop, Pecten maximus. In this study we investigated the effects on oxygen consumption, clearance rates and cellular turnover in juvenile P. maximus following 3 months laboratory exposure to four pCO2 treatments (290, 380, 750 and 1140 µatm). None of the exposure levels were found to have significant effect on the clearance rates, respiration rates, condition index or cellular turnover (RNA: DNA) of individuals. While it is clear that some life stages of marine bivalves appear susceptible to future levels of ocean acidification, particularly under food limiting conditions, the results from this study suggest that where food is in abundance, bivalves like juvenile P. maximus may display a tolerance to limited changes in seawater chemistry

    Prioritization of genes driving congenital phenotypes of patients with de novo genomic structural variants

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    Background:Genomic structural variants (SVs) can affect many genes and regulatory elements. Therefore, the molecular mechanisms driving the phenotypes of patients carrying de novo SVs are frequently unknown. Methods:We applied a combination of systematic experimental and bioinformatic methods to improve the molecular diagnosis of 39 patients with multiple congenital abnormalities and/or intellectual disability harboring apparent de novo SVs, most with an inconclusive diagnosis after regular genetic testing. Results: In 7 of these cases (18%), whole-genome sequencing analysis revealed disease-relevant complexities of the SVs missed in routine microarray-based analyses. We developed a computational tool to predict the effects on genes directly affected by SVs and on genes indirectly affected likely due to the changes in chromatin organization and impact on regulatory mechanisms. By combining these functional predictions with extensive phenotype information, candidate driver genes were identified in 16/39 (41%) patients. In 8 cases, evidence was found for the involvement of multiple candidate drivers contributing to different parts of the phenotypes. Subsequently, we applied this computational method to two cohorts containing a total of 379 patients with previously detected and classified de novo SVs and identified candidate driver genes in 189 cases (50%), including 40 cases whose SVs were previously not classified as pathogenic. Pathogenic position effects were predicted in 28% of all studied cases with balanced SVs and in 11% of the cases with copy number variants. Conclusions:These results demonstrate an integrated computational and experimental approach to predict driver genes based on analyses of WGS data with phenotype association and chromatin organization datasets. These analyses nominate new pathogenic loci and have strong potential to improve the molecular diagnosis of patients with de novo SVs

    Empirical Legal Studies Before 1940: A Bibliographic Essay

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    The modern empirical legal studies movement has well-known antecedents in the law and society and law and economics traditions of the latter half of the 20th century. Less well known is the body of empirical research on legal phenomena from the period prior to World War II. This paper is an extensive bibliographic essay that surveys the English language empirical legal research from approximately 1940 and earlier. The essay is arranged around the themes in the research: criminal justice, civil justice (general studies of civil litigation, auto accident litigation and compensation, divorce, small claims, jurisdiction and procedure, civil juries), debt and bankruptcy, banking, appellate courts, legal needs, legal profession (including legal education), and judicial staffing and selection. Accompanying the essay is an extensive bibliography of research articles, books, and reports

    My winter-time bride [music] /

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    For voice and piano.; Cover title.; Also available online http://nla.gov.au/nla.mus-an12825490

    Come to Bamboo Town [music] : where the little monkeys throw the cocoa-nuts down /

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    Cover carries photograph of Miss Irene Millar.; Also available online http://nla.gov.au/nla.mus-an13775872

    I like your company [music] /

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    Caption title.; "Miss Violet Stockelle's catchy chorus song"--Cover.; Cover bears portrait of Miss Violet Stockelle.; Words from chorus printed as text on cover.; Also available online http://nla.gov.au/nla.mus-vn4600916
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