290 research outputs found

    Detecting Distracted Driving with Deep Learning

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    © Springer International Publishing AG 2017Driver distraction is the leading factor in most car crashes and near-crashes. This paper discusses the types, causes and impacts of distracted driving. A deep learning approach is then presented for the detection of such driving behaviors using images of the driver, where an enhancement has been made to a standard convolutional neural network (CNN). Experimental results on Kaggle challenge dataset have confirmed the capability of a convolutional neural network (CNN) in this complicated computer vision task and illustrated the contribution of the CNN enhancement to a better pattern recognition accuracy.Peer reviewe

    Crash dieting: The effects of eating and drinking on driving performance

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    Previous research suggests that compared to mobile phone use, eating and drinking while driving is more common and is seen as lower risk by drivers. Nevertheless, snacking at the wheel can affect vehicle control to a similar extent as using a hands-free phone, and is actually a causal factor in more crashes. So far, though, there has not been a controlled empirical study of this problem. In an effort to fill this gap in the literature, we used the Brunel University Driving Simulator to test participants on a typical urban scenario. At designated points on the drive, which coincided with instructions to eat or drink, a critical incident was simulated by programming a pedestrian to walk in front of the car. Whilst the driving performance variables measured were relatively unaffected by eating and drinking, perceived driver workload was significantly higher and there were more crashes in the critical incident when compared to driving normally. Despite some methodological limitations of the study, when taken together with previous research, the evidence suggests that the physical demands of eating and drinking while driving can increase the risk of a crash

    Qualitative Methods and Sight-impairment: developing a toolkit for inclusive teaching.

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    Background Research methods is a key component of a psychology degree and recognised as a challenging topic to learn and teach. However, students who have sight-impairments experience additional barriers to its study, which could inhibit life-long learning in this area. Despite a growing body of literature to guide inclusive teaching practices for quantitative methods, little (if anything) is available for qualitative methods. However, these methods are traditionally taught using visual techniques (e.g. thematic maps), presenting barriers to learners with sight-impairments. This (ongoing) project explores the experience of learning qualitative methods from the perspectives of both students and tutors, in order to develop a “toolkit” to guide inclusive teaching-practice. Developing more inclusive teaching practice would likely benefit all students and help to promote engagement and learning of research methods. Design This inductive qualitative research forms part of a “Students as Academic Partners” project, due to be completed by May 2018. Methods Students and tutors from the University of Worcester, with experience of learning/teaching qualitative methods in relation to sight-impairment will be recruited using opportunistic and snowball sampling. Data will be collected using semi-structured interviews and analysed using thematic analysis. Results Barriers to learning qualitative methods and strategies adopted to manage these will be explored. In particular, it is important tutors recognise sight-impairment is not “one thing”, and that a range of strategies for adapting teaching-practice is required for diverse needs to be met. Conclusions The experience of learning qualitative methods for students who have sight-impairments has received little attention, making it difficult to identify inclusive teaching-practice in this area. This research outlines a toolkit with practical recommendations that tutors can draw on so their practice can better meet the needs of learners with sight-impairments

    Ultrafast Structural Dynamics of BlsA, a Photoreceptor from the Pathogenic Bacterium Acinetobacter baumannii

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    Acinetobacter baumannii is an important human pathogen that can form biofilms and persist under harsh environmental conditions. Biofilm formation and virulence are modulated by blue light, which is thought to be regulated by a BLUF protein, BlsA. To understand the molecular mechanism of light sensing, we have used steady-state and ultrafast vibrational spectroscopy to compare the photoactivation mechanism of BlsA to the BLUF photosensor AppA from Rhodobacter sphaeroides. Although similar photocycles are observed, vibrational data together with homology modeling identify significant differences in the ÎČ5 strand in BlsA caused by photoactivation, which are proposed to be directly linked to downstream signaling

    The impact of remote teaching on statistics learning and anxiety

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    In March 2020, staff and students at UK universities had to suddenly transition from on-campus teaching to remote learning as a result of the pandemic, which continued throughout the 2020/21 academic year. Unlike traditional online learners, students may lack the motivation or confidence to learn as effectively online particularly for modules such as statistics which students often find difficult or stressful face to face.This paper uses survey results from students studying elective and compulsory statistics modules in the 2020/21 academic year to gain an insight into remote learning of statistics from the students’ perspective.When compared to previous face to face teaching of statistics, students were less likely to actively engage with material, ask for help or work with peers remotely. Emotional wellbeing, motivation to learn, statistics anxiety and having a suitable learning environment all impacted on being able to learn statistics remotely. Although statistics anxiety in online teaching situations was generally lower, there was no evidence to suggest anxious students would benefit from online learning going forward

    Are students too anxious for statistics anxiety workshops?

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    Statistics is a widely taught subject in Higher Education but for many students, anxiety about statistics interferes with the learning process. Statistics anxiety workshops to help students understand and reduce statistics anxiety were developed by the authors and in 2020/21 delivered collaboratively and remotely with specific cohorts of students at three institutions. Prior to the workshops, all students within the targeted cohorts were asked to complete a survey which included measures of statistics anxiety, and asked if they were interested in attending the voluntary workshop. This enabled a comparison of the characteristics of groups who were interested or not. The workshops successfully attracted the targeted students, since those attending had higher overall statistics anxiety, software and maths anxiety, and anxiety around learning statistics. However, students with higher help seeking anxiety were less likely to attend

    Methadone-induced mortality in the treatment of chronic pain: Role of QT prolongation

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    Methadone is increasingly prescribed for chronic pain, yet the associated mortality appears to be rising disproportionately relative to other opioid analgesics. We review the available evidence on methadone-associated mortality, and explore potential pharmacokinetic and pharmacodynamic explanations for its greater apparent lethality. While methadone shares properties of central nervous system and respiratory depression with other opioids, methadone is unique as a potent blocker of the delayed rectifier potassium ion channel (IKr). This results in QT-prolongation and torsade de pointes (TdP) in susceptible individuals. In some individuals with low serum protein binding of methadone, the extent of blockade is roughly comparable to that of sotalol, a potent QT-prolonging drug. Predicting an individual’s propensity for methadone-induced TdP is difficult at present given the inherent limitations of the QT interval as a risk-stratifier combined with the multifactorial nature of the arrhythmia. Consensus recommendations have recently been published to mitigate the risk of TdP until further studies better define the arrhythmia risk factors for methadone. Studies are needed to provide insights into the clinical covariates most likely to result in methadone-associated arrhythmia and to assess the feasibility of current risk mitigation strategies

    The Prevalence and Volumetry of Pituitary Cysts in Children with Growth Hormone Deficiency and Idiopathic Short Stature

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    Background Pituitary cysts have been speculated to cause endocrinopathies. We sought to describe the prevalence and volumetry of pituitary cysts in patients with growth hormone deficiency (GHD) and idiopathic short stature (ISS). Methods Six hundred and eighteen children evaluated for growth failure at the Division of Pediatric Endocrinology at New York Medical College between the years 2002 and 2012, who underwent GH stimulation testing and had a brain magnetic resonance imaging (MRI) prior to initiating GH treatment were randomly selected to be a part of this study. High resolution MRI was used to evaluate the pituitary gland for size and the presence of a cyst. Cyst prevalence, cyst volume and percentage of the gland occupied by the cyst (POGO) were documented. Results Fifty-six patients had a cyst, giving an overall prevalence of 9.1%. The prevalence of cysts in GHD patients compared to ISS patients was not significant (13.5% vs. 5.7%, p=0.46). Mean cyst volume was greater in GHD patients than ISS patients (62.0 mm3 vs. 29.4 mm3, p=0.01). POGO for GHD patients was significantly greater (p=0.003) than for ISS patients (15.3%+/-12.8 vs. 7.1%+/-8.0). Observers were blinded to patient groups. Conclusions GHD patients had a significantly greater volume and POGO compared to ISS patients. This raises the question of whether cysts are implicated in the pathology of growth failure

    Psychological factors and cardiac repolarization instability during anger in implantable cardioverter defibrillator patients

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    BACKGROUND: Evidence indicates that emotions such as anger are associated with increased incidence of sudden cardiac death, but the biological mechanisms remain unclear. We tested the hypothesis that, in patients with sudden death vulnerability, anger would be associated with arrhythmic vulnerability, indexed by cardiac repolarization instability. METHODS: Patients with coronary artery disease (CAD) and an implantable cardioverter defibrillator (ICD; n = 41) and healthy controls (n = 26) gave an anger‐inducing speech (anger recall), rated their current (state) anger, and completed measures of trait (chronic) levels of Anger and Hostility. Repolarization instability was measured using QT Variability Index (QTVI) at resting baseline and during anger recall using continuous ECG. RESULTS: ICD patients had significantly higher QTVI at baseline and during anger recall compared with controls, indicating greater arrhythmic vulnerability overall. QTVI increased from baseline to anger recall to a similar extent in both groups. In ICD patients but not controls, during anger recall, self‐rated anger was related to QTVI (r = .44, p = .007). Trait (chronic) Anger Expression (r = .26, p = .04), Anger Control (r = −.26, p = .04), and Hostility (r = .25, p = .05) were each associated with the change in QTVI from baseline to anger recall (ΔQTVI). Moderation analyses evaluated whether psychological trait associations with ΔQTVI were specific to the ICD group. Results indicated that Hostility scores predicted ΔQTVI from baseline to anger recall in ICD patients (ÎČ = 0.07, p = .01), but not in controls. CONCLUSIONS: Anger increases repolarization lability, but in patients with CAD and arrhythmic vulnerability, chronic and acute anger interact to trigger cardiac repolarization lability associated with susceptibility to malignant arrhythmias
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