Einfluß des Schafgarbenpräparates auf Kaliumentzug und Blattwachstum

Zur Wirkung des biologisch-dynamischen Schafgarbenpräparates auf Radies im Kalimangelversuch Der Bericht erläutert Ergebnisse aus zwei 2-jährigen Blindversuchen mit den Versuchs-Faktoren: a) mineralische Kalidüngung und b) Bodenbehandlung mit und ohne Schafgarbenpräparat. In beiden Jahren wurde eine signifikante ertragssteigernde Wirkung der Kalidüngung festgestellt. Die Wirkung des Schafgarbenpräparates wirkte je nach Versuchsvariante und Jahr teils ausgleichend, teils ertragssteigernd. Die Wertung der Ergebnisse findet sich im Artikel: "Keimung, Wassereffizienz, Knolle und Blatt im Einfluss des Schafgarbenpräparates". Lebendige Erde 2/2000, S. 34-36

Keimung, Wassereffizienz, Knolle und Blatt im Einfluss des Schafgarbenpräparates

Zur Wirkung des biologisch-dynamischen Schafgarbenpräparates auf Radies im Kalimangel-Versuch Weitere Ergebnisse des Artikels: Einfluß des Schafgarbenpräparates auf Kaliumentzug und Blattwachstum, Lebendige Erde, 1/2000, S. 34-36) Der Bericht liefert weitere Ergebnisse aus dem in LE1/2000 beschriebenen Versuch zur Wirkung des Schafgarbenpräparates. In beiden Versuchsjahren konnten signifikante Wirkungen des Schafgarbenpräparates, positive Wirkungen auf Keimung, Keimblattwachstum, den Ertrag und die Wassereffizienz der Pflanzen, sowie Wechselwirkungen zwischen Schafgarbenbehandlung und Kaliumdüngung nachgewiesen werden

Impact of radiofrequency ablation for patients with varicose veins on the budget of the German statutory health insurance system

Objectives: In contrast to other countries, surgery still represents the common invasive treatment for varicose veins in Germany. However, radiofrequency ablation, e.g. ClosureFast, becomes more and more popular in other countries due to potential better results and reduced side effects. This treatment option may cause less follow-up costs and is a more convenient procedure for patients, which could justify an introduction in the statutory benefits catalogue. Therefore, we aim at calculating the budget impact of a general reimbursement of ClosureFast in Germany. Methods: To assess the budget impact of including ClosureFast in the German statutory benefits catalogue, we developed a multi-cohort Markov model and compared the costs of a “World with ClosureFast” with a “World without ClosureFast” over a time horizon of five years. To address the uncertainty of input parameters, we conducted three different types of sensitivity analysis (one-way, scenario, probabilistic). Results: In the Base Case scenario, the introduction of the ClosureFast system for the treatment of varicose veins saves costs of about 19.1 Mio. € over a time horizon of five years in Germany. However, the results scatter in the sensitivity analyses due to limited evidence of some key input parameters. Conclusions: Results of the budget impact analysis indicate that a general reimbursement of ClosureFast has the potential to be cost-saving in the German Statutory Health Insurance

Zuwendungen an die Fraktionen in den Landesparlamenten: finanzielle Zuwendungen, Sach- und Dienstleistungen

Grids are semantically different from other distributed systems. Therefore, performance analysis, just like any other technique requires careful reconsideration. This paper analyses the fundamental differences between grids and other systems and points out the special requirements raised to performance analysis. The aim of this paper is to survey the special problems, the possible directions and the existing solutions. A monitoring system, that is able to support the posed requirements is introduced as an example

HyperLeech: Stealthy System Analysis with Minimal Target Impact through DMA-Based Hypervisor Injection

In the recent past, malware began incorporating anti-forensic techniques at the kernel level to hinder analysts from gaining meaningful insights. Consequently, methods that allow the stealthy analysis of a system have become increasingly important. Recent approaches often rely on external devices that use Direct Memory Access (DMA) to transparently analyze volatile memory or shift a running system into a Virtual Machine (VM), performing forensics from the hypervisor level. While DMA suffers from low atomicity and a lack of semantics, virtualizing a running system usually requires privileged credentials and the installation of a kernel driver, which considerably alters a target’s state. In this report, we present HyperLeech, the first approach which uses DMA to stealthily inject a forensic hypervisor into the memory of a running target host, transparently shifting its operation into a hardware-accelerated VM. For injecting code minimally invasively, we use external PCILeech hardware to enable DMA to the target memory. Combining the advantages of hardware-supported virtualization with the benefits provided by DMA-based code injection, our approach can serve analysts as a stealthy and privileged execution layer that enables powerful live forensics and atomic memory snapshots without the risk of destroying evidence or alerting malware. Our experiments reveal that HyperLeech is sufficient for virtualizing modern multi-core hosts during runtime while neither causing a notable impact on the target’s processor and memory state nor introducing a significant performance overhead. To give the target the impression of possessing the entire available memory even after injecting our system, HyperLeech incorporates a sophisticated DMA-based memory swapping protocol that makes the content evicted by our hypervisor re-available upon request. Although HyperLeech might be misused for malicious purposes, we conclude that it provides new possibilities for stealthy system analysis and digital forensics, raising the bar for malware to evade detection

A Versatile Macromer-Based Glycosaminoglycan (sHA3) Decorated Biomaterial for Pro-Osteogenic Scavenging of Wnt Antagonists

High serum levels of Wnt antagonists are known to be involved in delayed bone defect healing. Pharmaceutically active implant materials that can modulate the micromilieu of bone defects with regard to Wnt antagonists are therefore considered promising to support defect regeneration. In this study, we show the versatility of a macromer based biomaterial platform to systematically optimize covalent surface decoration with high-sulfated glycosaminoglycans (sHA3) for efficient scavenging of Wnt antagonist sclerostin. Film surfaces representing scaffold implants were cross-copolymerized from three-armed biodegradable macromers and glycidylmethacrylate and covalently decorated with various polyetheramine linkers. The impact of linker properties (size, branching) and density on sHA3 functionalization efficiency and scavenging capacities for sclerostin was tested. The copolymerized 2D system allowed for finding an optimal, cytocompatible formulation for sHA3 functionalization. On these optimized sHA3 decorated films, we showed efficient scavenging of Wnt antagonists DKK1 and sclerostin, whereas Wnt agonist Wnt3a remained in the medium of differentiating SaOS-2 and hMSC. Consequently, qualitative and quantitative analysis of hydroxyapatite staining as a measure for osteogenic differentiation revealed superior mineralization on sHA3 materials. In conclusion, we showed how our versatile material platform enables us to efficiently scavenge and inactivate Wnt antagonists from the osteogenic micromilieu. We consider this a promising approach to reduce the negative effects of Wnt antagonists in regeneration of bone defects via sHA3 decorated macromer based macroporous implants. © 2020 by the authors. Licensee MDPI, Basel, Switzerland

Feebate and Scrappage Policy Instruments - Environmental and Economic Impacts for the EU27

This report presents the results and conclusions of a research carried out by the JRC/IPTS analysing two demand-side measures that can help improving the environmental performance of cars: The first instrument, the feebate system, is a way to differentiate the registration tax according to the CO2 emissions from cars. The second instrument, the scrappage policy is intended to encourage the owners of old cars to scrap their car earlier. The potential and consequences of technical options to reduce car weight are also analysed. The report builds a comprehensive assessment of these policy options at EU level, covering all major environmental life cycle impacts and the different economic impacts. The report is built upon IPTS research work, supported with a study subcontracted to a research consortium led by Transport&Mobility Leuven (TML) and involving Öko-Institut and ISI-Fraunhofer.JRC.J.2-The economics of climate change, energy and transpor