513 research outputs found

    Compression Deformation Behavior and Processing Map of Pure Copper

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    To reveal compression deformation behavior of pure copper, the deformation characteristics of pure copper have been investigated by means of compression tests in the temperature range of 400–900°C and strain rate range of 0.001–1 s⁻¹. The results show that the flow stress of pure copper increases with increasing strain rate and decreasing deformation temperature, which is characterized by work-hardening, dynamic recovery, dynamic recrystallization, and secondary work-hardening, etc. The activation energy of hot deformation is associated with deformation temperature and strain rate, and the average activation energy is calculated to be 303.8 kJ/mol. The flow stress prediction model based on GA+BP possess, is in very good agreement with the true stress curve, which is of significance to the guidance of hot working of pure copper. The flow instability occurs in the intermediate strain rate region (0.01–0.1 s⁻¹) base on the analysis of processing map, the high power dissipation correspond to the dynamic recrystallization. Appropriate reducing the deformation temperature or increasing the strain rate is beneficial for the grain refinement in the steady-state region of the processing map

    Effects of Exogenous Cellulase Source on In Vitro Fermentation Characteristics and Methane Production of Crop Straws and Grasses

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    In vitro fermentation experiments were conducted to investigate the effects of 3 sources of exogenous cellulase products (EC) at 4 dose rates (DR) (0, 12, 37 and 62 IU/g of DM) on degradation of forage and methane production by mixed rumen micro-organisms of goats. The maximum gas production (Vf) of grasses was higher (P<0.001) in Neocallimastix patriciarum (NP) group than those in Trichoderma reesei (TR) and Trichoderma longibrachiatum (TL) groups. Quadratic increases in dry matter degradation (DMD) of forage and neutral detergent fiber (NDFD) of straw were observed for all EC, with optimum DR in the low range. Supplementation of EC originated from TR and NP increased (P<0.001) DMD of forage compared to that from TL. Addition of EC originated from TR and NP also decreased pH value, ammonia nitrogen (NH3-N) and methane (CH4) production compared to that from TL. Quadratic decreases in pH value, NH3-N and CH4 of forage were noted for EC of TR and NP, and with optimum DR in the low range. For short chain fatty acid, the EC of NP increased total volatile fatty acid (TVFA) and acetate concentration and the ratio of acetate to propionate of forage compared with EC of TL and TR, and with optimum DR in the low to medium range. It was concluded that the source of EC differed in fiber degradation and methane emission, and with optimum DR of TR in the low range (from 12 to 37 U/g DM) in improving fiber degradation and decreasing methane emission

    Search for Invisible Decays of η\eta and η\eta^\prime in J/ψϕηJ/\psi \to \phi\eta and ϕη\phi \eta^\prime

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    Using a data sample of 58×10658\times 10^6 J/ψJ/\psi decays collected with the BES II detector at the BEPC, searches for invisible decays of η\eta and η\eta^\prime in J/ψJ/\psi to ϕη\phi\eta and ϕη\phi\eta^\prime are performed. The ϕ\phi signals, which are reconstructed in K+KK^+K^- final states, are used to tag the η\eta and η\eta^\prime decays. No signals are found for the invisible decays of either η\eta or η\eta^\prime, and upper limits at the 90% confidence level are determined to be 1.65×1031.65 \times 10^{-3} for the ratio B(ηinvisible)B(ηγγ)\frac{B(\eta\to \text{invisible})}{B(\eta\to\gamma\gamma)} and 6.69×1026.69\times 10^{-2} for B(ηinvisible)B(ηγγ)\frac{B(\eta^\prime\to \text{invisible})}{B(\eta^\prime\to\gamma\gamma)}. These are the first searches for η\eta and η\eta^\prime decays into invisible final states.Comment: 5 pages, 4 figures; Added references, Corrected typo

    Observation of Two New N* Peaks in J/psi -> ppinˉp pi^- \bar n and pˉπ+n\bar p\pi^+n Decays

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    The πN\pi N system in decays of J/ψNˉNπJ/\psi\to\bar NN\pi is limited to be isospin 1/2 by isospin conservation. This provides a big advantage in studying NπNN^*\to \pi N compared with πN\pi N and γN\gamma N experiments which mix isospin 1/2 and 3/2 for the πN\pi N system. Using 58 million J/ψJ/\psi decays collected with the Beijing Electron Positron Collider, more than 100 thousand J/ψpπnˉ+c.c.J/\psi \to p \pi^- \bar n + c.c. events are obtained. Besides two well known NN^* peaks at 1500 MeV and 1670 MeV, there are two new, clear NN^* peaks in the pπp\pi invariant mass spectrum around 1360 MeV and 2030 MeV. They are the first direct observation of the N(1440)N^*(1440) peak and a long-sought "missing" NN^* peak above 2 GeV in the πN\pi N invariant mass spectrum. A simple Breit-Wigner fit gives the mass and width for the N(1440)N^*(1440) peak as 1358±6±161358\pm 6 \pm 16 MeV and 179±26±50179\pm 26\pm 50 MeV, and for the new NN^* peak above 2 GeV as 2068±340+152068\pm 3^{+15}_{-40} MeV and 165±14±40165\pm 14\pm 40 MeV, respectively

    Haploinsufficiency of SIRT1 Enhances Glutamine Metabolism and Promotes Cancer Development

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    SIRT1, the most conserved mammalian NAD+-dependent protein deacetylase, plays a vital role in the regulation of metabolism, stress responses, and genome stability. However, the role of SIRT1 in the multi-step process leading to transformation and/or tumorigenesis, as either a tumor suppressor or tumor promoter, is complex and maybe dependent upon the context in which SIRT1 activity is altered, and the role of SIRT1 in tumor metabolism is unknown. Here we demonstrate that SIRT1 dose-dependently regulates cellular glutamine metabolism and apoptosis, which in turn differentially impact cell proliferation and cancer development. Heterozygous deletion of Sirt1 induces c-Myc expression, enhancing glutamine metabolism and subsequent proliferation, autophagy, stress resistance and cancer formation. In contrast, homozygous deletion of Sirt1 triggers cellular apoptotic pathways, increases cell death, diminishes autophagy, and reduces cancer formation. Consistent with the observed dose-dependence in cells, intestine-specific Sirt1 heterozygous mice have enhanced intestinal tumor formation, whereas intestine-specific Sirt1 homozygous knockout mice have reduced development of colon cancer. Furthermore, SIRT1 reduction but not deletion is associated with human colorectal tumors, and colorectal cancer patients with low protein expression of SIRT1 have a poor prognosis. Taken together, our findings indicate that the dose-dependent regulation of tumor metabolism and possibly apoptosis by SIRT1 mechanistically contributes to the observed dual roles of SIRT1 in tumorigenesis. Our study highlights the importance of maintenance of a suitable SIRT1 dosage for metabolic and tissue homeostasis, which will have important implications in SIRT1 small molecule activators/inhibitors based therapeutic strategies for cancers

    Measurements of the observed cross sections for e+ee^+e^-\to exclusive light hadrons containing π0π0\pi^0\pi^0 at s=3.773\sqrt s= 3.773, 3.650 and 3.6648 GeV

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    By analyzing the data sets of 17.3, 6.5 and 1.0 pb1^{-1} taken, respectively, at s=3.773\sqrt s= 3.773, 3.650 and 3.6648 GeV with the BES-II detector at the BEPC collider, we measure the observed cross sections for e+eπ+ππ0π0e^+e^-\to \pi^+\pi^-\pi^0\pi^0, K+Kπ0π0K^+K^-\pi^0\pi^0, 2(π+ππ0)2(\pi^+\pi^-\pi^0), K+Kπ+ππ0π0K^+K^-\pi^+\pi^-\pi^0\pi^0 and 3(π+π)π0π03(\pi^+\pi^-)\pi^0\pi^0 at the three energy points. Based on these cross sections we set the upper limits on the observed cross sections and the branching fractions for ψ(3770)\psi(3770) decay into these final states at 90% C.L..Comment: 7 pages, 2 figure

    Partial wave analysis of J/\psi \to \gamma \phi \phi

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    Using 5.8×107J/ψ5.8 \times 10^7 J/\psi events collected in the BESII detector, the radiative decay J/ψγϕϕγK+KKS0KL0J/\psi \to \gamma \phi \phi \to \gamma K^+ K^- K^0_S K^0_L is studied. The ϕϕ\phi\phi invariant mass distribution exhibits a near-threshold enhancement that peaks around 2.24 GeV/c2c^{2}. A partial wave analysis shows that the structure is dominated by a 0+0^{-+} state (η(2225)\eta(2225)) with a mass of 2.240.02+0.030.02+0.032.24^{+0.03}_{-0.02}{}^{+0.03}_{-0.02} GeV/c2c^{2} and a width of 0.19±0.030.04+0.060.19 \pm 0.03^{+0.06}_{-0.04} GeV/c2c^{2}. The product branching fraction is: Br(J/ψγη(2225))Br(η(2225)ϕϕ)=(4.4±0.4±0.8)×104Br(J/\psi \to \gamma \eta(2225))\cdot Br(\eta(2225)\to \phi\phi) = (4.4 \pm 0.4 \pm 0.8)\times 10^{-4}.Comment: 11 pages, 4 figures. corrected proof for journa

    Direct Measurements of Absolute Branching Fractions for D0 and D+ Inclusive Semimuonic Decays

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    By analyzing about 33 pb1\rm pb^{-1} data sample collected at and around 3.773 GeV with the BES-II detector at the BEPC collider, we directly measure the branching fractions for the neutral and charged DD inclusive semimuonic decays to be BF(D0μ+X)=(6.8±1.5±0.7)BF(D^0 \to \mu^+ X) =(6.8\pm 1.5\pm 0.7)% and BF(D+μ+X)=(17.6±2.7±1.8)BF(D^+ \to \mu^+ X) =(17.6 \pm 2.7 \pm 1.8)%, and determine the ratio of the two branching fractions to be BF(D+μ+X)BF(D0μ+X)=2.59±0.70±0.25\frac{BF(D^+ \to \mu^+ X)}{BF(D^0 \to \mu^+ X)}=2.59\pm 0.70 \pm 0.25

    A study of charged kappa in J/ψK±Ksππ0J/\psi \to K^{\pm} K_s \pi^{\mp} \pi^0

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    Based on 58×10658 \times 10^6 J/ψJ/\psi events collected by BESII, the decay J/ψK±Ksππ0J/\psi \to K^{\pm} K_s \pi^{\mp} \pi^0 is studied. In the invariant mass spectrum recoiling against the charged K(892)±K^*(892)^{\pm}, the charged κ\kappa particle is found as a low mass enhancement. If a Breit-Wigner function of constant width is used to parameterize the kappa, its pole locates at (849±7714+18)i(256±4022+46)(849 \pm 77 ^{+18}_{-14}) -i (256 \pm 40 ^{+46}_{-22}) MeV/c2c^2. Also in this channel, the decay J/ψK(892)+K(892)J/\psi \to K^*(892)^+ K^*(892)^- is observed for the first time. Its branching ratio is (1.00±0.190.32+0.11)×103(1.00 \pm 0.19 ^{+0.11}_{-0.32}) \times 10^{-3}.Comment: 14 pages, 4 figure

    Study of J/psi decays to Lambda Lambdabar and Sigma0 Sigma0bar

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    The branching ratios and Angular distributions for J/psi decays to Lambda Lambdabar and Sigma0 Sigma0bar are measured using BESII 58 million J/psi.Comment: 11 pages, 5 figure
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