15,620 research outputs found
Diagonally-reinforced beam–column joints reinforced under cyclic loading
The beam-column joints in a reinforced concrete frame are vulnerable to damage caused by seismic events. The conventional detailing using transverse hoops usually results in serious joint congestion, which creates contruction problems. This paper introduces a new detail especially developed for low to medium seismicity, which involves the use of additional diagonal bars in the joint. Six half-scale interior beam-column assemblies with different joint details, namely 'empty', nominal transverse reinforcement and diagonal bars, tested under reversed cyclic loading are reported. The empty joint is not suitable even under moderate seismicity. The test results show that the joints containing the newly proposed detail, with or without axial compressive load present in the column, exhibit better behaviour at the lower range of ductility factors in terms of higher load-carrying capacity, greater stiffness and less strength degradation. Therefore, the newly proposed joint detail is suitable for beam-column joints of reinforced concrete buildings located in regions of low to medium seismic risk.published_or_final_versio
Collection, spillback, and dissipation in pedestrian evacuation: A network-based method
We present a method of predicting pedestrian route choice behavior and physical congestion during the evacuation of indoor areas with internal obstacles. Under the proposed method, a network is first constructed by discretizing the space into regular hexagonal cells and giving these cells potentials before a modified cell transmission model is employed to predict the evolution of pedestrian flow in the network over time and space. Several properties of this cell transmission model are explored. The method can be used to predict the evolution of pedestrian flow over time and space in indoor areas with internal obstacles and to investigate the collection, spillback, and dissipation behavior of pedestrians passing through a bottleneck. The cell transmission model is further extended to imitate the movements of multiple flows of pedestrians with different destinations. An algorithm based on generalized cell potential is also developed to assign the pedestrian flow. © 2010 Elsevier Ltd.postprin
A nonlinear equation system approach to the dynamic stochastic user equilibrium simultaneous route and departure time choice problem
postprin
Fabrication and characteristics of a GaInP/GaAs heterojunction bipolar transistor using a selective buried sub-collector
A C-doped GaInP/GaAs heterojunction bipolar transistor (HBT) with a selective buried sub-collector has been fabricated by two growth steps. The active HBT region was made on the selective buried sub-collector layer with minimum overlap of the extrinsic base and the sub-collector region resulting in substantial reduction of the base-collector capacitance. The experiment shows that the base-collector capacitance is reduced to about half of that of a conventional HBT while the base resistance remains unchanged resulting in a 40-50% increase in the maximum oscillation frequency. Both DC and RF characteristics are investigated and compared with a conventional HBT. A current gain of 40 cutoff frequency of 50 GHz and maximum oscillation frequency of 140 GHz were obtained for the GaInP/GaAs HBT. It is demonstrated that the selective buried sub-collector provides an effective means for enhancing RF performance of an HBT. © 1997 IEEE.published_or_final_versio
An intersection-movement-based stochastic dynamic user optimal route choice model for assessing network performance
Different from traditional methods, this paper formulates the logit-based stochastic dynamic user optimal (SDUO) route choice problem as a fixed point (FP) problem in terms of intersection movement choice probabilities, which contain travelers’ route information so that the realistic effects of physical queues can be captured in the formulation when a physical-queue traffic flow model is adopted, and that route enumeration and column generation heuristics can be avoided in the solution procedure when efficient path sets are used. The choice probability can be either destination specific or origin–destination specific, resulting into two formulations. To capture the effect of physical queues in these FP formulations, the link transmission model is modified for the network loading and travel time determination. The self-regulated averaging method (SRAM) was adopted to solve the FP formulations. Numerical examples were developed to illustrate the properties of the problem and the effectiveness of the solution method. The proposed models were further used to evaluate the effect of information quality and road network improvement on the network performance in terms of total system travel time (TSTT) and the cost of total vehicle emissions (CTVE). Numerical results show that providing better information quality, enhancing link outflow capacity, or constructing a new road can lead to poor network performance.postprin
Black Hole Emission in String Theory and the String Phase of Black Holes
String theory properly describes black-hole evaporation. The quantum string
emission by Black Holes is computed. The black-hole temperature is the Hawking
temperature in the semiclassical quantum field theory (QFT) regime and becomes
the intrinsic string temperature, T_s, in the quantum (last stage) string
regime. The QFT-Hawking temperature T_H is upper bounded by the string
temperature T_S. The black hole emission spectrum is an incomplete gamma
function of (T_H - T_S). For T_H << T_S, it yields the QFT-Hawking emission.
For T_H \to T_S, it shows highly massive string states dominate the emission
and undergo a typical string phase transition to a microscopic `minimal' black
hole of mass M_{\min} or radius r_{\min} (inversely proportional to T_S) and
string temperature T_S. The string back reaction effect (selfconsistent black
hole solution of the semiclassical Einstein equations) is computed. Both, the
QFT and string black hole regimes are well defined and bounded.The string
`minimal' black hole has a life time tau_{min} simeq (k_B c)/(G hbar [T_S]^3).
The semiclassical QFT black hole (of mass M and temperature T_H) and the string
black hole (of mass M_{min} and temperature T_S) are mapped one into another by
a `Dual' transform which links classical/QFT and quantum string regimes.Comment: LaTex, 22 pages, Lectures delivered at the Chalonge School, Nato ASI:
Phase Transitions in the Early Universe: Theory and Observations. To appear
in the Proceedings, Editors H. J. de Vega, I. Khalatnikov, N. Sanchez.
(Kluwer Pub
Preconditioning of mesenchymal stromal cells with low-intensity ultrasound: influence on chondrogenesis and directed SOX9 signaling pathways
Background: Continuous low-intensity ultrasound (cLIUS) facilitates the chondrogenic differentiation of human mesenchymal stromal cells (MSCs) in the absence of exogenously added transforming growth factor-beta (TGFβ) by upregulating the expression of transcription factor SOX9, a master regulator of chondrogenesis. The present study evaluated the molecular events associated with the signaling pathways impacting SOX9 gene and protein expression under cLIUS.
Methods: Human bone marrow-derived MSCs were exposed to cLIUS stimulation at 14 kPa (5 MHz, 2.5 Vpp) for 5 min. The gene and protein expression of SOX9 was evaluated. The specificity of SOX9 upregulation under cLIUS was determined by treating the MSCs with small molecule inhibitors of select signaling molecules, followed by cLIUS treatment. Signaling events regulating SOX9 expression under cLIUS were analyzed by gene expression, immunofluorescence staining, and western blotting.
Results: cLIUS upregulated the gene expression of SOX9 and enhanced the nuclear localization of SOX9 protein when compared to non-cLIUS-stimulated control. cLIUS was noted to enhance the phosphorylation of the signaling molecule ERK1/2. Inhibition of MEK/ERK1/2 by PD98059 resulted in the effective abrogation of cLIUS-induced SOX9 expression, indicating that cLIUS-induced SOX9 upregulation was dependent on the phosphorylation of ERK1/2. Inhibition of integrin and TRPV4, the upstream cell-surface effectors of ERK1/2, did not inhibit the phosphorylation of ERK1/2 and therefore did not abrogate cLIUS-induced SOX9 expression, thereby suggesting the involvement of other mechanoreceptors. Consequently, the effect of cLIUS on the actin cytoskeleton, a mechanosensitive receptor regulating SOX9, was evaluated. Diffused and disrupted actin fibers observed in MSCs under cLIUS closely resembled actin disruption by treatment with cytoskeletal drug Y27632, which is known to increase the gene expression of SOX9. The upregulation of SOX9 under cLIUS was, therefore, related to cLIUS-induced actin reorganization. SOX9 upregulation induced by actin reorganization was also found to be dependent on the phosphorylation of ERK1/2.
Conclusions: Collectively, preconditioning of MSCs by cLIUS resulted in the nuclear localization of SOX9, phosphorylation of ERK1/2 and disruption of actin filaments, and the expression of SOX9 was dependent on the phosphorylation of ERK1/2 under cLIUS
A model-based approach to recovering the structure of a plant from images
We present a method for recovering the structure of a plant directly from a
small set of widely-spaced images. Structure recovery is more complex than
shape estimation, but the resulting structure estimate is more closely related
to phenotype than is a 3D geometric model. The method we propose is applicable
to a wide variety of plants, but is demonstrated on wheat. Wheat is made up of
thin elements with few identifiable features, making it difficult to analyse
using standard feature matching techniques. Our method instead analyses the
structure of plants using only their silhouettes. We employ a generate-and-test
method, using a database of manually modelled leaves and a model for their
composition to synthesise plausible plant structures which are evaluated
against the images. The method is capable of efficiently recovering accurate
estimates of plant structure in a wide variety of imaging scenarios, with no
manual intervention
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