167 research outputs found
O processo de filtragem de políticas: Entendendo as respostas distintas do National College Completion Agenda en los Estados Unidos
The United States has faced stagnant postsecondary education degree completion rates for over a decade. When coupled with improved educational outcomes in other nations, the one-time world leader in higher education attainment has precipitously declined in standing internationally. Coupling this reality with the need for a more educated workforce domestically led President Barack Obama to proclaim improving higher education completion rates a national imperative in 2009. Despite input from the federal government, due to the decentralized nature of American postsecondary education, individual states maintain primary responsibility for governance and policy decisions. Consequently, there has been a range of state responses to improving college completion. Through a comparative case analysis, this study considers a putatively homogenous region to investigate state-level factors that “filtered” the national college completion agenda to distinct responses in Georgia, South Carolina, and Texas.Estados Unidos se ha enfrentado a tasas de finalización de estudios de educación postsecundaria estancadas durante más de una década. Cuando se combina con mejores resultados educativos en otras naciones, el líder mundial en el logro de la educación superior ha disminuido precipitadamente en su posición internacional. Al combinar esta realidad con la necesidad de una fuerza de trabajo más educada, el presidente Barack Obama proclamó que mejorar las tasas de finalización de la educación superior era un imperativo nacional en 2009. A pesar del aporte del gobierno federal, debido a la naturaleza descentralizada de la educación postsecundaria estadounidense, responsabilidad por la gobernanza y las decisiones de política. En consecuencia, ha habido una variedad de respuestas estatales para mejorar la finalización de la universidad. A través de un análisis comparativo de casos, este estudio considera una región putativamente homogénea para investigar los factores a nivel estatal que "filtraron" la agenda de finalización de la universidad nacional a respuestas distintas en Georgia, Carolina del Sur y Texas.Os Estados Unidos foram submetidos a uma série de finalizações de estudos de educação pós-graduados durante mais de uma década. A combinação de todos os resultados educativos em outras nações, o mundo em curso no domínio da educação superior tem sido precipitadamente na sua posição internacional. Al preliminar this realidad to necesidad de una fuerza de trabajo más educada, el presidente Barack Obama proclamou que as melhores tarefas de finalização da educação superior era um imperativo nacional em 2009. A pesar delporte do governo federal, debito a naturaleza descentralizada de la educación postsecundaria estadounidense, responsabilidad por la gobernanza y las decisiones de political. En consecuencia, ha habito una variedad de respuestas estatales for mejorar la finalización de la universidad. A case to un analogis comparative case, this study is a region was applied in port homogénea for investigating the factors a level estatal that "filtraron" the agenda of finalisation of the universidad nationals and conditions in Georgia, Carolina del Sur and Texas
Targeted Subsidization of Postsecondary Education Enrollment in Minnesota: A Policy Evaluation.
Minnesota's policy in the early 1980s of raising tuition for postsecondary education while increasing the money available for need-based student financial aid is examined.Did the policy affect high school students' expectations and plans for further education? Did it affect their access to education? The study looks at the whole picture of equity in financing postsecondary education. A CURA Reporter article in June 1986 summarizes this study.A project of the Interactive Research Grants Program, CURA and the Office of the Vice President for Academic Affairs
ELF3 controls thermoresponsive growth in Arabidopsis
Plant development is highly responsive to ambient temperature, and this trait has been linked to the ability of plants to adapt to climate change [1]. The mechanisms by which natural populations modulate their thermoresponsiveness are not known [2]. To address this, we surveyed Arabidopsis accessions for variation in thermal responsiveness of elongation growth and mapped the corresponding loci. We find that the transcriptional regulator EARLY FLOWERING3 (ELF3) controls elongation growth in response to temperature. Through a combination of modeling and experiments, we show that high temperature relieves the gating of growth at night, highlighting the importance of temperature-dependent repressors of growth. ELF3 gating of transcriptional targets responds rapidly and reversibly to changes in temperature. We show that the binding of ELF3 to target promoters is temperature dependent, suggesting a mechanism where temperature directly controls ELF3 activity
Nonsurgical closure of femoral pseudoaneurysms complicating cardiac catheterization and percutaneous transluminal coronary angioplasty
AbstractObjectives. This study was performed to describe the initial experience and follow-up of ultrasound-guided compression of pseudoaneurysms in patients receiving systemic anticoagulant or antiplatelet therapy, or both, after recent cardiac catheterization or percutaneous transluminal coronary angioplasty.Background. Femoral artery pseudoaneurysm formation after an interventional procedure is becoming more common as larger caliber catheters and prolonged anticoagulant and antiplatelet therapy are being used. Traditional treatment of this complication has been surgical repair. This study describes a new method of closing femoral pseudoaneurysms by using external compression guided by Doppler color flow imaging.Methods. Fifteen patients, 3 undergoing cardiac catheterization and 12 undergoing coronary angioplasty, developed an expansile groin mass at the vascular access site diagnosed as a femoral artery pseudoaneurysm by Doppler ultrasound. Seven of the patients had undergone coronary stenting and were receiving postprocedural anticoagulant therapy. These patients underwent progressive graded mechanical (C-clamp) external compression guided by ultrasound. The mechanical compression was titrated to obliterate the vascular tracts to these aneurysms and maintain adequate flow in the femoral artery.Results. After an average compression time of 30 min (range 10 to 120), these tracts remained closed. Follow-up ultrasound examination at 24 h or later confirmed continued closure in all. Conclusions. This study suggests that nonsurgical closure of femoral pseudoaneurysms is feasible. This technique may be valuable in managing vascular access-related complications after diagnostic and interventional procedures, even in patients requiring prolonged anticoagulant therapy
Poincare gauge theory of gravity: Friedman cosmology with even and odd parity modes. Analytic part
We propose a cosmological model in the framework of the Poincar\'e gauge
theory of gravity (PG). The gravitational Lagrangian is quadratic in curvature
and torsion. In our specific model, the Lagrangian contains (i) the curvature
scalar and the curvature pseudo-scalar linearly and quadratically
(including an term) and (ii) pieces quadratic in the torsion {\it vector}
and the torsion {\it axial} vector (including a term). We show generally that in quadratic PG models we have nearly
the same number of parity conserving terms (`world') and of parity violating
terms (`shadow world'). This offers new perspectives in cosmology for the
coupling of gravity to matter and antimatter. Our specific model generalizes
the fairly realistic `torsion cosmologies' of Shie-Nester-Yo (2008) and Chen et
al.\ (2009). With a Friedman type ansatz for an orthonormal coframe and a
Lorentz connection, we derive the two field equations of PG in an explicit form
and discuss their general structure in detail. In particular, the second field
equation can be reduced to first order ordinary differential equations for the
curvature pieces and . Including these along with certain
relations obtained from the first field equation and curvature definitions, we
present a first order system of equations suitable for numerical evaluation.
This is deferred to the second, numerical part of this paper.Comment: Latex computerscript, 25 pages; mistakes corrected, references added,
notation and title slightly changed; accepted by Phys. Rev.
A pangenome graph reference of 30 chicken genomes allows genotyping of large and complex structural variants
Background
The red junglefowl, the wild outgroup of domestic chickens, has historically served as a reference for genomic studies of domestic chickens. These studies have provided insight into the etiology of traits of commercial importance. However, the use of a single reference genome does not capture diversity present among modern breeds, many of which have accumulated molecular changes due to drift and selection. While reference-based resequencing is well-suited to cataloging simple variants such as single-nucleotide changes and short insertions and deletions, it is mostly inadequate to discover more complex structural variation in the genome.
Methods
We present a pangenome for the domestic chicken consisting of thirty assemblies of chickens from different breeds and research lines.
Results
We demonstrate how this pangenome can be used to catalog structural variants present in modern breeds and untangle complex nested variation. We show that alignment of short reads from 100 diverse wild and domestic chickens to this pangenome reduces reference bias by 38%, which affects downstream genotyping results. This approach also allows for the accurate genotyping of a large and complex pair of structural variants at the K feathering locus using short reads, which would not be possible using a linear reference.
Conclusions
We expect that this new paradigm of genomic reference will allow better pinpointing of exact mutations responsible for specific phenotypes, which will in turn be necessary for breeding chickens that meet new sustainability criteria and are resilient to quickly evolving pathogen threats
'To live and die [for] Dixie': Irish civilians and the Confederate States of America
Around 20,000 Irishmen served in the Confederate army in the Civil War. As a result, they left behind, in various Southern towns and cities, large numbers of friends, family, and community leaders. As with native-born Confederates, Irish civilian support was crucial to Irish participation in the Confederate military effort. Also, Irish civilians served in various supporting roles: in factories and hospitals, on railroads and diplomatic missions, and as boosters for the cause. They also, however, suffered in bombardments, sieges, and the blockade. Usually poorer than their native neighbours, they could not afford to become 'refugees' and move away from the centres of conflict. This essay, based on research from manuscript collections, contemporary newspapers, British Consular records, and Federal military records, will examine the role of Irish civilians in the Confederacy, and assess the role this activity had on their integration into Southern communities. It will also look at Irish civilians in the defeat of the Confederacy, particularly when they came under Union occupation. Initial research shows that Irish civilians were not as upset as other whites in the South about Union victory. They welcomed a return to normalcy, and often 'collaborated' with Union authorities. Also, Irish desertion rates in the Confederate army were particularly high, and I will attempt to gauge whether Irish civilians played a role in this. All of the research in this paper will thus be put in the context of the Drew Gilpin Faust/Gary Gallagher debate on the influence of the Confederate homefront on military performance. By studying the Irish civilian experience one can assess how strong the Confederate national experiment was. Was it a nation without a nationalism
Constructions of vulnerability in comparative perspective: Scottish protection policies and the trouble with "adults at risk"
This paper places Scottish adult support and protection (ASP) policy in the context of debates about the nature of 'vulnerability' and its usefulness as a defining concept in law and social policy. It examines the construction of 'adults at risk' in ASP policy, using a comparison with the construction of children in Scottish child protection policy, on the one hand, and women in Scottish domestic abuse policy, on the other, to illuminate the nature of the vulnerability that ASP considers itself to be addressing. It then problematises this construction, drawing both on the social model of disability and on an ethic of care. It concludes that current ASP policy remains underpinned by unhelpful assumptions about disabled people, older people and people with mental or physical health problems. A more inclusive understanding of vulnerability would be more empowering to these people and others, in policies concerned with mistreatment and abuse
Light Microsopy Module, International Space Station Premier Automated Microscope
The Light Microscopy Module (LMM) was launched to the International Space Station (ISS) in 2009 and began science operations in 2010. It continues to support Physical and Biological scientific research on ISS. During 2015, if all goes as planned, five experiments will be completed: [1] Advanced Colloids Experiments with a manual sample base -3 (ACE-M-3), [2] the Advanced Colloids Experiment with a Heated Base -1 (ACE-H-1), [3] (ACE-H-2), [4] the Advanced Plant Experiment -03 (APEX-03), and [5] the Microchannel Diffusion Experiment (MDE). Preliminary results, along with an overview of present and future LMM capabilities will be presented; this includes details on the planned data imaging processing and storage system, along with the confocal upgrade to the core microscope. [1] New York University: Paul Chaikin, Andrew Hollingsworth, and Stefano Sacanna, [2] University of Pennsylvania: Arjun Yodh and Matthew Gratale, [3] a consortium of universities from the State of Kentucky working through the Experimental Program to Stimulate Competitive Research (EPSCoR): Stuart Williams, Gerold Willing, Hemali Rathnayake, et al., [4] from the University of Florida and CASIS: Anna-Lisa Paul and Rob Ferl, and [5] from the Methodist Hospital Research Institute from CASIS: Alessandro Grattoni and Giancarlo Canavese
- …