Laser performance of perylenebis (dicarboximide) dyes with long secondary alkyl chains

The laser performance and related photophysical properties of two very soluble perylene dyes with long chain secondary alkyl groups were investigated in cyclohexane solution. With a dye laser as pump source a tuning range of 555–580 nm was obtained at an optimum concentration of 3×10–4 M. The quantum efficiencies (=0.29 and 0.21) were better than 1/2 that of rhodamine 6G. No photodegradation was observed over an excitation period of several hours

Astrochemistry and Astrophotonics for an Antarctic Observatory

Due to its location and climate, Antarctica offers unique conditions for long-period observations across a broad wavelength regime, where important diagnostic lines for molecules and ions can be found, that are essential to understand the chemical properties of the interstellar medium. In addition to the natural benefits of the site, new technologies, resulting from astrophotonics, may allow miniaturised instruments, that are easier to winterise and advanced filters to further reduce the background in the infrared.Comment: 4 pages, to be published in EAS Publications Series, Vol. 40, Proc. of 3rd ARENA conferenc

Continuous synthesis of pyridocarbazoles and initial photophysical and bioprobe characterization

Pyridocarbazoles when ligated to transition metals yield high affinity kinase inhibitors. While batch photocyclizations enable the synthesis of these heterocycles, the non-oxidative Mallory reaction only provides modest yields and difficult to purify mixtures. We demonstrate here that a flow-based Mallory cyclization provides superior results and enables observation of a clear isobestic point. The flow method allowed us to rapidly synthesize ten pyridocarbazoles and for the first time to document their interesting photophysical attributes. Preliminary characterization reveals that these molecules might be a new class of fluorescent bioprobe

Suppression of the near-infrared OH night sky lines with fibre Bragg gratings - first results

The background noise between 1 and 1.8 microns in ground-based instruments is dominated by atmospheric emission from hydroxyl molecules. We have built and commissioned a new instrument, GNOSIS, which suppresses 103 OH doublets between 1.47 - 1.7 microns by a factor of ~1000 with a resolving power of ~10,000. We present the first results from the commissioning of GNOSIS using the IRIS2 spectrograph at the AAT. The combined throughput of the GNOSIS fore-optics, grating unit and relay optics is ~36 per cent, but this could be improved to ~46 per cent with a more optimal design. We measure strong suppression of the OH lines, confirming that OH suppression with fibre Bragg gratings will be a powerful technology for low resolution spectroscopy. The integrated OH suppressed background between 1.5 and 1.7 microns is reduced by a factor of 9 compared to a control spectrum using the same system without suppression. The potential of low resolution OH suppressed spectroscopy is illustrated with example observations. The GNOSIS background is dominated by detector dark current below 1.67 microns and by thermal emission above 1.67 microns. After subtracting these we detect an unidentified residual interline component of ~ 860 +/ 210 ph/s/m^2/micron/arcsec^2. This component is equally bright in the suppressed and control spectra. We have investigated the possible source of the interline component, but were unable to discriminate between a possible instrumental artifact and intrinsic atmospheric emission. Resolving the source of this emission is crucial for the design of fully optimised OH suppression spectrographs. The next generation OH suppression spectrograph will be focussed on resolving the source of the interline component, taking advantage of better optimisation for a FBG feed. We quantify the necessary improvements for an optimal OH suppressing fibre spectrograph design.Comment: Accepted for publication in MNRAS. 15 pages, 18 figure

Faseroptischer Sensor und Verfahren zur Herstellung

DE 102009005162 A1 UPAB: 20100806 NOVELTY - The optic fiber sensor has a fiber core (1) within a mantle (2) and a sensor material, which changes color when in contact with the matter under scrutiny. A recess (3) is centered at the end of the fiber, on its optical axis, with an adhesive bond to secure an optically transparent micro ball (4) coated with the sensor dyestuff material (5). USE - The optic fiber sensor is for measurement of materials or their concentration e.g. molecular acids in solutions and gas phases. ADVANTAGE - The micro ball, with the sensor material, is firmly bonded to the end of the optic fiber

Six-color time-resolved Förster resonance energy transfer for ultrasensitive multiplexed biosensing

Simultaneous monitoring of multiple molecular interactions and multiplexed detection of several diagnostic biomarkers at very low concentrations have become important issues in advanced biological and chemical sensing. Here we present an optically multiplexed six-color Forster resonance energy transfer (FRET) biosensor for simultaneous monitoring of five different individual binding events. We combined simultaneous FRET from one Tb complex to five different organic dyes measured in a filter-based time-resolved detection format with a sophisticated spectral crosstalk correction, which results in very efficient background suppression. The advantages and robustness of the multiplexed FRET sensor were exemplified by analyzing a 15-component lung cancer immunoassay involving 10 different antibodies and five different tumor markers in a single 50 mu L human serum sample. The multiplexed biosensor offers clinically relevant detection limits in the low picomolar (ng/mL) concentration range for all five markers, thus providing an effective early screening tool for lung cancer with the possibility of distinguishing small-cell from non-small-cell lung carcinoma. This novel technology will open new doors for multiple biomarker diagnostics as well as multiplexed real-time imaging and spectroscopy