Capture on High Curvature Region: Aggregation of Colloidal Particle Bound to Giant Phospholipid Vesicles

A very recent observation on the membrane mediated attraction and ordered aggregation of colloidal particles bound to giant phospholipid vesicles (I. Koltover, J. O. R\"{a}dler, C. R. Safinya, Phys. Rev. Lett. {\bf 82}, 1991(1999)) is investigated theoretically within the frame of Helfrich curvature elasticity theory of lipid bilayer fluid membrane. Since the concave or waist regions of the vesicle possess the highest local bending energy density, the aggregation of colloidal beads on these places can reduce the elastic energy in maximum. Our calculation shows that a bead in the concave region lowers its energy $\sim 20 k_B T$. For an axisymmetrical dumbbell vesicle, the local curvature energy density along the waist is equally of maximum, the beads can thus be distributed freely with varying separation distance.Comment: 12 pages, 2 figures. REVte

The evaluation of (social-)psychological comfort in clothing, a possible approach

This paper presents the first results of a PhD research on psychological comfort of clothing. In order to understand and conceptualize the psychological aspects of clothing comfort, a variation of the Delphi Method was used to seek opinions from experts. This method was chosen because of its consensus-building features. The results were obtained from a qualitative text analysis, conducted over the experts’ responses to the first round of questions. The analytic process shed some light on the formation of the psychological comfort concept as well as the potential attributes to be evaluated when assessing this comfort dimension.This work is supported by FEDER funds through the Competitivity Factors Operational Programme - COMPETE and by national funds through FCT – Foundation for Science and Technology within the scope of the project POCI-01-0145-FEDER-007136. The first author would also like to gratefully acknowledge the support from the Araucaria Foundation of Paraná State and the Federal University of Technology, specially, the Fashion Design Department and the Office of Research and Graduate Studies.info:eu-repo/semantics/publishedVersio

Quantification of Political Risk in Energy Foresight - A Method Overview

Uncertainty is almost ubiquitous in energy related decision making. It has many sources, multiple facets and numerous implications. From the uncertainties surrounding Global Warming over the incertitude of future technological progress to the volatility of fuel and other energy prices, the uncertainties account for an important part of the current energy strategy puzzle. One key element of this puzzle is however political risk. Especially when it comes to the supply of oil and gas, where around 70 % of the worldwide resources are concentrated in what is sometimes labelled the "strategic ellipse" (cf. e.g. Rempel et al. 2006), encompassing the region from the Arabian peninsula over the surroundings of the Caspian Sea up to the most important Siberian hydrocarbon reservoirs. How should political risk be taken into account when aiming at solving the energy strategy puzzle? This is the key issue addressed in this paper, however with a clear focus on the first step of strategic decision making, namely the environment analysis. Thereby environment does not mean only the natural environment but the entire surrounding world which is relevant for the decision making. Consequently the first point to be discussed in the following is energy related decision making in general and the role of risk herein in particular (cf. Section 2). Then a typology of risks and especially political risks is sketched in Section 3 before approaches to the modelling and quantification of political risk are reviewed in Section 4

Solar Neutrinos and the Principle of Equivalence

We study the proposed solution of the solar neutrino problem which requires a flavor nondiagonal coupling of neutrinos to gravity. We adopt a phenomenological point of view and investigate the consequences of the hypothesis that the neutrino weak interaction eigenstates are linear combinations of the gravitational eigenstates which have slightly different couplings to gravity, $f_1G$ and $f_2G$, $|f_1-f_2| << 1$, corresponding to a difference in red-shift between electron and muon neutrinos, $\Delta z/(1+z) \sim |f_1 - f_2|$. We perform a $\chi^2$ analysis of the latest available solar neutrino data and obtain the allowed regions in the space of the relevant parameters. The existing data rule out most of the parameter space which can be probed in solar neutrino experiments, allowing only $|f_1 - f_2| \sim 3 \times 10^{-14}$ for small values of the mixing angle ($2 \times 10^{-3} \le \sin^2(2\theta_G) \le 10^{-2}$) and $10^{-16} \stackrel{<}{\sim} |f_1 - f_2| \stackrel{<}{\sim}10^{-15}$ for large mixing ($0.6 \le \sin^2(2\theta_G) \le 0.9$). Measurements of the $^8{\rm B}$-neutrino energy spectrum in the SNO and Super-Kamiokande experiments will provide stronger constraints independent of all considerations related to solar models. We show that these measurements will be able to exclude part of the allowed region as well as to distinguish between conventional oscillations and oscillations due to the violation of the equivalence principle.Comment: 20 pages + 4 figures, IASSNS-AST 94/5

How Well Do We (and Will We) Know Solar Neutrino Fluxes and Oscillation Parameters?

Assuming neutrino oscillations occur, the pp electron neutrino flux is uncertain by at least a factor of two, the ${\rm ^8B}$ flux by a factor of five, and the ${\rm ^7Be}$ flux by a factor of forty-five. Calculations of the expected results of future solar neutrino experiments (SuperKamiokande, SNO, BOREXINO, ICARUS, HELLAZ, and HERON) are used to illustrate the extent to which these experiments will restrict the range of the allowed neutrino mixing parameters. We present an improved formulation of the ``luminosity constraint'' and show that at 95\% confidence limit this constraint establishes the best available limits on the rate of creation of pp neutrinos in the solar interior and provides the best upper limit to the ${\rm ^7Be}$ neutrino flux.Comment: 37 pages, uuencoded Z-compressed postscript file (with figures); Submitted to Physical Review

Consensus guidelines on analgesia and sedation in dying intensive care unit patients

BACKGROUND: Intensivists must provide enough analgesia and sedation to ensure dying patients receive good palliative care. However, if it is perceived that too much is given, they risk prosecution for committing euthanasia. The goal of this study is to develop consensus guidelines on analgesia and sedation in dying intensive care unit patients that help distinguish palliative care from euthanasia. METHODS: Using the Delphi technique, panelists rated levels of agreement with statements describing how analgesics and sedatives should be given to dying ICU patients and how palliative care should be distinguished from euthanasia. Participants were drawn from 3 panels: 1) Canadian Academic Adult Intensive Care Fellowship program directors and Intensive Care division chiefs (N = 9); 2) Deputy chief provincial coroners (N = 5); 3) Validation panel of Intensivists attending the Canadian Critical Care Trials Group meeting (N = 12). RESULTS: After three Delphi rounds, consensus was achieved on 16 statements encompassing the role of palliative care in the intensive care unit, the management of pain and suffering, current areas of controversy, and ways of improving palliative care in the ICU. CONCLUSION: Consensus guidelines were developed to guide the administration of analgesics and sedatives to dying ICU patients and to help distinguish palliative care from euthanasia

Neutrino masses: From fantasy to facts

Theory suggests the existence of neutrino masses, but little more. Facts are coming close to reveal our fantasy: solar and atmospheric neutrino data strongly indicate the need for neutrino conversions, while LSND provides an intriguing hint. The simplest ways to reconcile these data in terms of neutrino oscillations invoke a light sterile neutrino in addition to the three active ones. Out of the four neutrinos, two are maximally-mixed and lie at the LSND scale, while the others are at the solar mass scale. These schemes can be distinguished at neutral-current-sensitive solar & atmospheric neutrino experiments. I discuss the simplest theoretical scenarios, where the lightness of the sterile neutrino, the nearly maximal atmospheric neutrino mixing, and the generation of $\Delta {m^2}_\odot$ & $\Delta {m^2}_{atm}$ all follow naturally from the assumed lepton-number symmetry and its breaking. Although the most likely interpretation of the present data is in terms of neutrino-mass-induced oscillations, one still has room for alternative explanations, such as flavour changing neutrino interactions, with no need for neutrino mass or mixing. Such flavour violating transitions arise in theories with strictly massless neutrinos, and may lead to other sizeable flavour non-conservation effects, such as $\mu \to e + \gamma$, $\mu-e$ conversion in nuclei, unaccompanied by neutrino-less double beta decay.Comment: 33 pages, latex, 16 figures. Invited Talk at Ioannina Conference, Symmetries in Intermediate High Energy Physics and its Applications, Oct. 1998, to be published by Springer Tracts in Modern Physics. Festschrift in Honour of John Vergados' 60th Birthda

Constraints on neutrino oscillation parameters from the measurement of day-night solar neutrino fluxes at Super-Kamiokande

A search for day-night variations in the solar neutrino flux resulting from neutrino oscillations has been carried out using the 504 day sample of solar neutrino data obtained at Super-Kamiokande. The absence of a significant day-night variation has set an absolute flux independent exclusion region in the two neutrino oscillation parameter space.Comment: 11 pages, 3 figures, submitted to PRL, single-spacin

Key components of learning ecologies: a Delphi assessment

This is the accepted version of the following article: González‐Sanmamed, M. , Muñoz‐Carril, P. and Santos‐Caamaño, F. (2019), Key components of learning ecologies: A Delphi assessment. Br J Educ Technol, 50: 1639-1655, which has been published in final form at https://doi.org/10.1111/bjet.12805. This article may be used for non-commercial purposes in accordance with the Wiley Self-Archiving Policy (http://www.wileyauthors.com/self-archiving)The educational landscape has changed in recent years, requiring reflection about new pedagogical methods and theories. There are three important perspectives as drivers of pedagogical reflection: lifelong and life‐wide learning, the idea of learning as a social construct in which internal elements and changing external factors converge, and the recognition of technology as a resource that can promote ubiquitous and expanded learning. Learning ecology has been proposed as a conceptual and empirical framework, but its still emergent nature along with its multidimensionality and complexity require further exploration. The Delphi study we present as part of a broader research project aims to identify the components of learning ecologies. Three panel rounds with international experts were carried out, after which two important dimensions emerged in the structure of learning ecologies. The first is related to intrinsic “learning dispositions,” which is made up of three categories: the subject's ideas about learning, their motivations and expectations. The second dimension, called “learning processes,” comprises four components: relationships, resources, actions and context. The identification of the components of learning ecologies and their influence on formal, non‐formal and informal training processes will provide guidance for educational policies and help to better organize training programmesWe thank the Spanish Ministry of Economy and Competitiveness for their support of our study under a research project entitled “How the best University Teachers Learn: Impact on Learning Ecologies on Quality of Teaching” (ECO4LEARN‐HE) (Reference: EDU2015‐67907‐R)S

Standardising Clinical Caremaps: Model, Method and Graphical Notation for Caremap Specification

Standardising care can improve patient safety and outcomes, and reduce the cost of providing healthcare services. Caremaps were developed to standardise care, but contemporary caremaps are not standardised. Confusion persists in terms of terminology, structure, content and development process. Unlike existing methods in the literature, the approach, model and notation presented in this chapter pays special attention to incorporation of clinical decision points as first-class citizens within the modelling process. The resulting caremap with decision points is evaluated through creation of a caremap for women with gestational diabetes mellitus. The proposed method was found to be an effective way for comprehensively specifying all features of caremaps in a standardised way that can be easily understood by clinicians. This chapter contributes a new standardised method, model and notation for caremap content, structure and development