22,416 research outputs found

    The inferior caval vein draining into the left atrial cavity : a rare case

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    The inferior vena cava (IVC) draining into the left atrium (LA) is exceedingly rare in the setting of the usual atrial arrangement (situs solitus). This article describes a patient with this unique anomaly, and its repair.peer-reviewe

    A critical review of household recycling barriers in the United Kingdom

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    The UK recycling rate fluctuates between 45% and 47% and has consistently failed to meet the 65% target set by the post-Brexit Resource and Waste Strategy. Understanding the issues surrounding the low recycling rate in metropolitan cities in the UK will help to overcome these recycling challenges. The review examines the current situation with regards to the recycling rate and tonnage of waste produced in the UK based on available secondary waste flow data and explores different barriers related to household recycling. Many areas giving rise to the recycling challenges have been identified, including waste policy constraints, lack of effective communication, public engagement, physical barriers, service constraints, human factors, and socio-economic barriers. The literature review reveals factors such as waste policy, communication, and physical factors were the most important aspects in influencing recycling rate or output. It is concluded that a multi-dimension intervention is required, which includes a thorough review of waste policy, a more stringent enforcement, an improved communication strategy, and a more integrated planning development policy to mitigate issues affecting the UK’s low recycling rate or output. This approach will propel the local authorities to launch or initiate effective recycling management and to put in place the required infrastructure to facilitate effective recycling activities

    A new dawn? The Roman Catholic Church and environmental issues

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    This is a PDF version of an article published in New Blackfriars© 1997. The definitive version is available at www.blackwell-synergy.com.This article discusses the stance of the Roman Catholic Church on environmental issues and argues that the Church tends to stay on the fringe rather than get involved. Some of the ways in which Roman Catholic theologians have incorporated environmental issues into theological reflection is discussed, as are environmental challenges facing the Church in Britain (conservation, resources, biodiversity, animal welfare, biotechnology, cooperate/individual ethics, environmental justice, economics/policy development, and global issues)

    Voltage-dependent Block of the Cystic Fibrosis Transmembrane Conductance Regulator Cl- Channel by Two Closely Related Arylaminobenzoates

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    The gene defective in cystic fibrosis encodes a Cl- channel, the cystic fibrosis transmembrane conductance regulator (CFTR). CFTR is blocked by diphenylamine-2-carboxylate (DPC) when applied extracellularly at millimolar concentrations. We studied the block of CFTR expressed in Xenopus oocytes by DPC or by a closely related molecule, flufenamic acid (FFA). Block of whole-cell CFTR currents by bath-applied DPC or by FFA, both at 200 µM, requires several minutes to reach full effect. Blockade is voltage dependent, suggesting open-channel block: currents at positive potentials are not affected but currents at negative potentials are reduced. The binding site for both drugs senses ~40% of the electric field across the membrane, measured from the inside. In single-channel recordings from excised patches without blockers, the conductance was 8.0 ± 0.4 pS in symmetric 150 mM Cl^-. A subconductance state, measuring ~60% of the main conductance, was often observed. Bursts to the full open state lasting up to tens of seconds were uninterrupted at depolarizing membrane voltages. At hyperpolarizing voltages, bursts were interrupted by brief closures. Either DPC or FFA (50 µM) applied to the cytoplasmic or extracellular face of the channel led to an increase in flicker at V_m =-100 mV and not at V_m = +100 mV, in agreement with whole-cell experiments. DPC induced a higher frequency of flickers from the cytoplasmic side than the extracellular side. FFA produced longer closures than DPC; the FFA closed time was roughly equal (~ 1.2 ms) at -100 mV with application from either side. In cell-attached patch recordings with DPC or FFA applied to the bath, there was flickery block at V_m = -100 mV, confirming that the drugs permeate through the membrane to reach the binding site. The data are consistent with the presence of a single binding site for both drugs, reached from either end of the channel. Open-channel block by DPC or FFA may offer tools for use with site-directed mutagenesis to describe the permeation pathway

    Barrier and internal wave contributions to the quantum probability density and flux in light heavy-ion elastic scattering

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    We investigate the properties of the optical model wave function for light heavy-ion systems where absorption is incomplete, such as α+40\alpha + ^{40}Ca and α+16\alpha + ^{16}O around 30 MeV incident energy. Strong focusing effects are predicted to occur well inside the nucleus, where the probability density can reach values much higher than that of the incident wave. This focusing is shown to be correlated with the presence at back angles of a strong enhancement in the elastic cross section, the so-called ALAS (anomalous large angle scattering) phenomenon; this is substantiated by calculations of the quantum probability flux and of classical trajectories. To clarify this mechanism, we decompose the scattering wave function and the associated probability flux into their barrier and internal wave contributions within a fully quantal calculation. Finally, a calculation of the divergence of the quantum flux shows that when absorption is incomplete, the focal region gives a sizeable contribution to nonelastic processes.Comment: 16 pages, 15 figures. RevTeX file. To appear in Phys. Rev. C. The figures are only available via anonynous FTP on ftp://umhsp02.umh.ac.be/pub/ftp_pnt/figscat

    A comparative analysis of the relationship between flood experience and private flood mitigation behaviour in the regions of England

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    There has been a move towards a more integrated approach to flood risk management, which includes a stronger focus on property level measures. However, in England the uptake of these measures remains low. Flood experience has been found to influence preparedness (i.e., the uptake of measures), but even experience does not always result in an increase in preparedness. We investigate the variations in the relationship between experience and preparedness for the regions of England as defined by the Environment Agency. Analysis of survey data collected by the Environment Agency among the at risk population between 1997 and 2004 was undertaken to determine the differences between the seven regions. We find that in the South West, Southern and Anglian regions increases in preparedness with increasing experience are higher compared to other regions. In the Thames, Midlands and North West regions the preparedness increases less with increasing experience. We explore the influence of other factors influencing flood mitigation behaviour that have been previously found in the literature and find that the differences between regions are correlated with the severity of experienced flooding and whether English is the first language of the respondents

    Does woman + a network = career progression?

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    Question: I am an ambitious and talented junior manager who has recently been hired by FAB plc, a large multinational company. I am also a woman and, as part of my induction pack, have received an invitation to join FABFemmes - the in-company women's network. I don't think my gender has been an obstacle to my success thus far and so I don't really feel the need to join. But on the other hand I don't want to turn my back on something that might offer me a useful source of contacts to help me advance up the career ladder. What would be the best thing to do? - Ms Ambitious, UK

    Laboratory And Astronomical Detection Of The Negative Molecular Ion C3N-

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    The negative molecular ion C3N- has been detected at millimeter wavelengths in a low-pressure laboratory discharge, and then with frequencies derived from the laboratory data in the molecular envelope of IRC+10216. Spectroscopic constants derived from laboratory measurements of 12 transitions between 97 and 378 GHz allow the rotational spectrum to be calculated well into the submillimeter-wave band to 0.03 km s(-1) or better in equivalent radial velocity. Four transitions of C3N- were detected in IRC+10216 with the IRAM 30 m telescope at precisely the frequencies calculated from the laboratory measurements. The column density of C3N- is 0.5% that of C3N, or approximately 20 times greater than that of C4H- relative to C4H. The C3N- abundance in IRC+10216 is compared with a chemical model calculation by Petrie & Herbst. An upper limit in TMC-1 for C3N- relative to C3N (< 0.8%) and a limit for C4H- relative to C4H (< 0.004%) that is 5 times lower than that found in IRC+10216, were obtained from observations with the NRAO 100 m Green Bank Telescope (GBT). The fairly high concentration ofNRFKorean government MEST 2012R1A1A1014646, 2012M4A2026720Southeast Physics Network (SEP-Net)Science and Technology Facilities Council ST/F002858/1, ST/I000976/1Swedish Research Council 2009-4088U.S. NSF AST-0708176, AST-1009799NASA NNX07AH09G, NNG04G177G, NNX11AE09GChandra grant SAO TM8-9009XBiochemistr

    Dust-forming molecules in VY Canis Majoris (and Betelgeuse)

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    The formation of inorganic dust in circumstellar environments of evolved stars is poorly understood. Spectra of molecules thought to be most important for the nucleation, i.e. AlO, TiO, and TiO2, have been recently detected in the red supergiant VY CMa. These molecules are effectively formed in VY CMa and the observations suggest that non-equilibrium chemistry must be involved in their formation and nucleation into dust. In addition to exploring the recent observations of VY CMa, we briefly discuss the possibility of detecting these molecules in the dust-poor circumstellar environment of Betelgeuse.Comment: contribution to Betelgeuse Workshop 2012: "The physics of Red Supergiants: recent advances and open questions", 26-29 Nov 2012 Paris (France
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