Geometric Path Integrals. A Language for Multiscale Biology and Systems Robustness

In this paper we suggest that, under suitable conditions, supervised learning can provide the basis to formulate at the microscopic level quantitative questions on the phenotype structure of multicellular organisms. The problem of explaining the robustness of the phenotype structure is rephrased as a real geometrical problem on a fixed domain. We further suggest a generalization of path integrals that reduces the problem of deciding whether a given molecular network can generate specific phenotypes to a numerical property of a robustness function with complex output, for which we give heuristic justification. Finally, we use our formalism to interpret a pointedly quantitative developmental biology problem on the allowed number of pairs of legs in centipedes

Pseudodifferential multi-product representation of the solution operator of a parabolic equation

By using a time slicing procedure, we represent the solution operator of a second-order parabolic pseudodifferential equation on $\R^n$ as an infinite product of zero-order pseudodifferential operators. A similar representation formula is proven for parabolic differential equations on a compact Riemannian manifold. Each operator in the multi-product is given by a simple explicit Ansatz. The proof is based on an effective use of the Weyl calculus and the Fefferman-Phong inequality.Comment: Comm. Partial Differential Equations to appear (2009) 28 page

Boundedness of Pseudodifferential Operators on Banach Function Spaces

We show that if the Hardy-Littlewood maximal operator is bounded on a separable Banach function space $X(\mathbb{R}^n)$ and on its associate space $X'(\mathbb{R}^n)$, then a pseudodifferential operator $\operatorname{Op}(a)$ is bounded on $X(\mathbb{R}^n)$ whenever the symbol $a$ belongs to the H\"ormander class $S_{\rho,\delta}^{n(\rho-1)}$ with $0<\rho\le 1$, $0\le\delta<1$ or to the the Miyachi class $S_{\rho,\delta}^{n(\rho-1)}(\varkappa,n)$ with $0\le\delta\le\rho\le 1$, $0\le\delta0$. This result is applied to the case of variable Lebesgue spaces $L^{p(\cdot)}(\mathbb{R}^n)$.Comment: To appear in a special volume of Operator Theory: Advances and Applications dedicated to Ant\'onio Ferreira dos Santo

A time-frequency analysis perspective on Feynman path integrals

The purpose of this expository paper is to highlight the starring role of time-frequency analysis techniques in some recent contributions concerning the mathematical theory of Feynman path integrals. We hope to draw the interest of mathematicians working in time-frequency analysis on this topic, as well as to illustrate the benefits of this fruitful interplay for people working on path integrals.Comment: 26 page

Finite Temperature Casimir Effect for a Massless Fractional Klein-Gordon field with Fractional Neumann Conditions

This paper studies the Casimir effect due to fractional massless Klein-Gordon field confined to parallel plates. A new kind of boundary condition called fractional Neumann condition which involves vanishing fractional derivatives of the field is introduced. The fractional Neumann condition allows the interpolation of Dirichlet and Neumann conditions imposed on the two plates. There exists a transition value in the difference between the orders of the fractional Neumann conditions for which the Casimir force changes from attractive to repulsive. Low and high temperature limits of Casimir energy and pressure are obtained. For sufficiently high temperature, these quantities are dominated by terms independent of the boundary conditions. Finally, validity of the temperature inversion symmetry for various boundary conditions is discussed.Comment: 31 page

Regularizing effect and local existence for non-cutoff Boltzmann equation

The Boltzmann equation without Grad's angular cutoff assumption is believed to have regularizing effect on the solution because of the non-integrable angular singularity of the cross-section. However, even though so far this has been justified satisfactorily for the spatially homogeneous Boltzmann equation, it is still basically unsolved for the spatially inhomogeneous Boltzmann equation. In this paper, by sharpening the coercivity and upper bound estimates for the collision operator, establishing the hypo-ellipticity of the Boltzmann operator based on a generalized version of the uncertainty principle, and analyzing the commutators between the collision operator and some weighted pseudo differential operators, we prove the regularizing effect in all (time, space and velocity) variables on solutions when some mild regularity is imposed on these solutions. For completeness, we also show that when the initial data has this mild regularity and Maxwellian type decay in velocity variable, there exists a unique local solution with the same regularity, so that this solution enjoys the $C^\infty$ regularity for positive time

Structural resolvent estimates and derivative nonlinear Schrodinger equations

A refinement of uniform resolvent estimate is given and several smoothing estimates for Schrodinger equations in the critical case are induced from it. The relation between this resolvent estimate and radiation condition is discussed. As an application of critical smoothing estimates, we show a global existence results for derivative nonlinear Schrodinger equations.Comment: 21 page

A Conformally Invariant Holographic Two-Point Function on the Berger Sphere

We apply our previous work on Green's functions for the four-dimensional quaternionic Taub-NUT manifold to obtain a scalar two-point function on the homogeneously squashed three-sphere (otherwise known as the Berger sphere), which lies at its conformal infinity. Using basic notions from conformal geometry and the theory of boundary value problems, in particular the Dirichlet-to-Robin operator, we establish that our two-point correlation function is conformally invariant and corresponds to a boundary operator of conformal dimension one. It is plausible that the methods we use could have more general applications in an AdS/CFT context.Comment: 1+49 pages, no figures. v2: Several typos correcte