Entropic sampling dynamics of the globally-coupled kinetic Ising model

The entropic sampling dynamics based on the reversible information transfer to and from the environment is applied to the globally coupled Ising model in the presence of an oscillating magnetic field. When the driving frequency is low enough, coherence between the magnetization and the external magnetic field is observed; such behavior tends to weaken with the system size. The time-scale matching between the intrinsic time scale, defined in the absence of the external magnetic field, and the extrinsic time scale, given by the inverse of the driving frequency, is used to explain the observed coherence behavior.Comment: 8 page

Electronic and Magnetic Properties of Electron-doped Superconductor, Sm_{1.85}Ce_{0.15}CuO_{4-delta}

Temperature-dependent magnetization (M(T)) and specific heat (C_p(T)) measurements were carried out on single crystal Sm_{1.85}Ce_{0.15}CuO_{4-delta} (T_c = 16.5 K). The magnetic anisotropy in the static susceptibility, chi {equiv} M/H, is apparent not only in its magnitude but also in its temperature dependence, with chi_{perp} for H{perp}c larger than chi_{parallel} for H{parallel}c. For both field orientations, chi does not follow the Curie-Weiss behavior due to the small energy gap of the J = 7/2 multiplet above the J = 5/2 ground-state multiplet. However, with increasing temperature, chi_{parallel}(T) exhibits a broad minimum near 100 K and then a slow increase while chi_{perp}(T) shows a monotonic decrease. A sharp peak in C_p(T) at 4.7 K manifests an antiferromagnetic ordering. The electronic contribution, gamma, to C_p(T) is estimated to be gamma = 103.2 (7) mJ/moleSmK^2. The entropy associated with the magnetic ordering is much smaller than Rln2, where R is the gas constant, which is usually expected for the doublet ground state of Sm^{+3}. The unusual magnetic and electronic properties evident in M(T) and C_p(T) are probably due to a strong anisotropic interaction between conduction electrons and localized electrons at Sm^{+3} sites.Comment: 5 pages, 5 encapsulated postscript figures, late

Direct Evidence of the Discontinuous Character of the Kosterlitz-Thouless Jump

It is numerically shown that the discontinuous character of the helicity modulus of the two-dimensional XY model at the Kosterlitz-Thouless (KT) transition can be directly related to a higher order derivative of the free energy without presuming any {\it a priori} knowledge of the nature of the transition. It is also suggested that this higher order derivative is of intrinsic interest in that it gives an additional characteristics of the KT transition which might be associated with a universal number akin to the universal value of the helicity modulus at the critical temperature.Comment: 4 pages, to appear in PR

Evidence of Two Distinct Dynamic Critical Exponents in Connection with Vortex Physics

The dynamic critical exponent $z$ is determined from numerical simulations for the three-dimensional (3D) lattice Coulomb gas (LCG) and the 3D XY models with relaxational dynamics. It is suggested that the dynamics is characterized by two distinct dynamic critical indices $z_0$ and $z$ related to the divergence of the relaxation time $\tau$ by $\tau\propto \xi^{z_0}$ and $\tau\propto k^{-z}$, where $\xi$ is the correlation length and $k$ the wavevector. The values determined are $z_0\approx 1.5$ and $z\approx 1$ for the 3D LCG and $z_0\approx 1.5$ and $z\approx 2$ for the 3D XY model. It is argued that the nonlinear $IV$ exponent relates to $z_0$, whereas the usual Hohenberg-Halperin classification relates to $z$. Possible implications for the interpretation of experiments are pointed out. Comparisons with other existing results are discussed.Comment: to appear in PR

Scaling determination of the nonlinear I-V characteristics for 2D superconducting networks

It is shown from computer simulations that the current-voltage ($I$-$V$) characteristics for the two-dimensional XY model with resistively-shunted Josephson junction dynamics and Monte Carlo dynamics obeys a finite-size scaling form from which the nonlinear $I$-$V$ exponent $a$ can be determined to good precision. This determination supports the conclusion $a=z+1$, where $z$ is the dynamic critical exponent. The results are discussed in the light of the contrary conclusion reached by Tang and Chen [Phys. Rev. B {\bf 67}, 024508 (2003)] and the possibility of a breakdown of scaling suggested by Bormann [Phys. Rev. Lett. {\bf 78}, 4324 (1997)].Comment: 6 pages, to appear in PR

Fractal Profit Landscape of the Stock Market

We investigate the structure of the profit landscape obtained from the most basic, fluctuation based, trading strategy applied for the daily stock price data. The strategy is parameterized by only two variables, p and q. Stocks are sold and bought if the log return is bigger than p and less than -q, respectively. Repetition of this simple strategy for a long time gives the profit defined in the underlying two-dimensional parameter space of p and q. It is revealed that the local maxima in the profit landscape are spread in the form of a fractal structure. The fractal structure implies that successful strategies are not localized to any region of the profit landscape and are neither spaced evenly throughout the profit landscape, which makes the optimization notoriously hard and hypersensitive for partial or limited information. The concrete implication of this property is demonstrated by showing that optimization of one stock for future values or other stocks renders worse profit than a strategy that ignores fluctuations, i.e., a long-term buy-and-hold strategy.Comment: 12 pages, 4 figure

Finite-temperature resistive transition in the two-dimensional XY gauge glass model

We investigate numerically the resistive transition in the two-dimensional XY gauge glass model. The resistively-shunted junction dynamics subject to the fluctuating twist boundary condition is used and the linear resistances in the absence of an external current at various system sizes are computed. Through the use of the standard finite-size scaling method, the finite temperature resistive transition is found at $k_BT_c = 0.22(2)$ (in units of the Josephson coupling strength) with dynamic critical exponent $z = 2.0(1)$ and the static exponent $\nu = 1.2(2)$, in contrast to widely believed expectation of the zero-temperature transition. Comparisons with existing experiments and simulations are also made.Comment: 5 pages in two columns, 4 eps figures included, to appear in PR

Reducing combinatorial uncertainties: A new technique based on MT2 variables

We propose a new method to resolve combinatorial ambiguities in hadron collider events involving two invisible particles in the final state. This method is based on the kinematic variable MT2 and on the MT2-assisted-on-shell reconstruction of invisible momenta, that are reformulated as `test' variables Ti of the correct combination against the incorrect ones. We show how the efficiency of the single Ti in providing the correct answer can be systematically improved by combining the different Ti and/or by introducing cuts on suitable, combination-insensitive kinematic variables. We illustrate our whole approach in the specific example of top anti-top production, followed by a leptonic decay of the W on both sides. However, by construction, our method is also directly applicable to many topologies of interest for new physics, in particular events producing a pair of undetected particles, that are potential dark-matter candidates. We finally emphasize that our method is apt to several generalizations, that we outline in the last sections of the paper.Comment: 1+23 pages, 8 figures. Main changes in v3: (1) discussion at the end of sec. 2 improved; (2) added sec. 4.2 about the method's dependence on mass information. Matches journal versio

Immune evasion in cancer: mechanistic basis and therapeutic strategies

Cancer immune evasion is a major stumbling block in designing effective anticancer therapeutic strategies. Although considerable progress has been made in understanding how cancers evade destructive immunity, measures to counteract tumor escape have not kept pace. There are a number of factors that contribute to tumor persistence despite having a normal host immune system. Immune editing is one of the key aspects why tumors evade surveillance causing the tumors to lie dormant in patients for years through “equilibrium” and “senescence” before re- emerging. In addition, tumors exploit several immunological processes such as targeting the regulatory T cell function or their secretions, antigen presentation, modifying the production of immune suppressive mediators, tolerance and immune deviation. Besides these, tumor heterogeneity and metastasis also play a critical role in tumor growth. A number of potential targets like promoting Th1, NK cell, γδ T cell responses, inhibiting Treg functionality, induction of IL-12, use of drugs including phytochemicals have been designed to counter tumor progression with much success. Some natural agents and phytochemicals merit further study. For example, use of certain key polysaccharide components from mushrooms and plants have shown possess therapeutic impact on tumor-imposed genetic instability, anti-growth signaling, replicative immortality, deregulated metabolism etc. In this review, we will discuss the advances made towards understanding the basis of cancer immune evasion and summarize the efficacy of various therapeutic measures and targets that have been developed or are being investigated to enhance tumor rejection