307 research outputs found

    Rejection of the hypothesis that Markarian 501 TeV photons are pure Bose-Einstein condensates

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    The energy spectrum of the Blazar type galaxy Markarian 501 (Mrk 501) as measured by the High-Energy-Gamma-Ray Astronomy (HEGRA) air Cerenkov telescopes extends beyond 16 TeV and constitutes the most energetic photons observed from an extragalactic object. A fraction of the emitted spectrum is possibly absorbed in interactions with low energy photons of the diffuse extragalactic infrared radiation, which in turn offers the unique possibility to measure the diffuse infrared radiation density by TeV spectroscopy. The upper limit on the density of the extragalactic infrared radiation derived from the TeV observations imposes constraints on models of galaxy formation and stellar evolution. One of the recently published ideas to overcome severe absorption of TeV photons is based upon the assumption that sources like Mrk 501 could produce Bose-Einstein condensates of coherent photons. The condensates would have a higher survival probability during the transport in the diffuse radiation field and could mimic TeV air shower events. The powerful stereoscopic technique of the HEGRA air Cerenkov telescopes allows to test this hypothesis by reconstructing the penetration depths of TeV air shower events: Air showers initiated by Bose-Einstein condensates are expected to reach the maximum of the shower development in the atmosphere earlier than single photon events. By comparing the energy-dependent penetration depths of TeV photons from Mrk 501 with those from the TeV standard-candle Crab Nebula and simulated air shower events, we can reject the hypothesis that TeV photons from Mrk 501 are pure Bose-Einstein condensates.Comment: 9 pages, 2 figures, published by ApJ Letters, revised version (simulation results added

    Integrin-mediated traction force enhances paxillin molecular associations and adhesion dynamics that increase the invasiveness of tumor cells into a three-dimensional extracellular matrix.

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    Metastasis requires tumor cells to navigate through a stiff stroma and squeeze through confined microenvironments. Whether tumors exploit unique biophysical properties to metastasize remains unclear. Data show that invading mammary tumor cells, when cultured in a stiffened three-dimensional extracellular matrix that recapitulates the primary tumor stroma, adopt a basal-like phenotype. Metastatic tumor cells and basal-like tumor cells exert higher integrin-mediated traction forces at the bulk and molecular levels, consistent with a motor-clutch model in which motors and clutches are both increased. Basal-like nonmalignant mammary epithelial cells also display an altered integrin adhesion molecular organization at the nanoscale and recruit a suite of paxillin-associated proteins implicated in invasion and metastasis. Phosphorylation of paxillin by Src family kinases, which regulates adhesion turnover, is similarly enhanced in the metastatic and basal-like tumor cells, fostered by a stiff matrix, and critical for tumor cell invasion in our assays. Bioinformatics reveals an unappreciated relationship between Src kinases, paxillin, and survival of breast cancer patients. Thus adoption of the basal-like adhesion phenotype may favor the recruitment of molecules that facilitate tumor metastasis to integrin-based adhesions. Analysis of the physical properties of tumor cells and integrin adhesion composition in biopsies may be predictive of patient outcome

    The TeV Energy Spectrum of Mkn 501 Measured with the Stereoscopic Telescope System of HEGRA during 1998 and 1999

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    During 1997, the BL Lac object Mkn 501 went into an extraordinary state of high X-ray and TeV gamma-ray activity, lasting more than 6 months. In this paper we report on the TeV emission characteristics of the source in the subsequent years of 1998 and 1999 as measured with the Stereoscopic Cherenkov Telescope System of HEGRA (La Palma, Canary Islands). Our observations reveal a 1998-1999 mean emission level at 1 TeV of 1/3 of the flux of the Crab Nebula, a factor of 10 lower than during the year of 1997. A dataset of 122 observations hours with the HEGRA telescope system makes it possible to assess for the first time the Mkn 501 TeV energy spectrum for a mean flux level substantially below that of the Crab Nebula with reasonable statistical accuracy. Excluding the data of a strong flare, we find evidence that the 1998--1999 low-flux spectrum is substantially softer (by 0.44+-0.1(stat) in spectral index) than the 1997 time averaged spectrum. The 500 GeV to 10 TeV energy spectrum can well be described by a power law model with exponential cutoff: dN/dE ~ E^(-alpha) exp(-E/E0) with alpha=2.31+-0.22(stat), and E0=5.1 (-2.3+7.8)(stat) TeV. Within statistical accuracy, also a pure power law model gives an acceptable fit to the data: dN/dE ~ E^(-Gamma) with Gamma=2.76+-0.08(stat). After presenting the 1998-1999 TeV characteristics of the source we discuss the implications of the results.Comment: Accepted for publication in The Astrophysical Journal, Part 1, on August 4th, 200

    Evidence for TeV gamma ray emission from Cassiopeia A

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    232 hours of data were accumulated from 1997 to 1999, using the HEGRA Stereoscopic Cherenkov Telescope System to observe the supernova remnant Cassiopeia A. TeV gamma ray emission was detected at the 5 sigma level, and a flux of (5.8 +- 1.2(stat) +- 1.2(syst)) 10^(-9) ph m^(-2) s^(-1) above 1 TeV was derived. The spectral distribution is consistent with a power law with a differential spectral index of -2.5 +- 0.4(stat) +- 0.1(syst) between 1 and 10 TeV. As this is the first report of the detection of a TeV gamma ray source on the "centi-Crab" scale, we present the analysis in some detail. Implications for the acceleration of cosmic rays depend on the details of the source modeling. We discuss some important aspects in this paper.Comment: 9 pages, 6 figures, accepted for publication in Astronomy & Astrophysic

    The Energy Spectrum of TeV Gamma-Rays from the Crab Nebula as measured by the HEGRA system of imaging air Cherenkov telescopes

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    The Crab Nebula has been observed by the HEGRA (High-Energy Gamma-Ray Astronomy) stereoscopic system of imaging air Cherenkov telescopes (IACTs) for a total of about 200 hrs during two observational campaigns: from September 1997 to March 1998 and from August 1998 to April 1999. The recent detailed studies of system performance give an energy threshold and an energy resolution for gamma-rays of 500 GeV and ~ 18%, respectively. The Crab energy spectrum was measured with the HEGRA IACT system in a very broad energy range up to 20 TeV, using observations at zenith angles up to 65 degrees. The Crab data can be fitted in the energy range from 1 to 20 TeV by a simple power-law, which yields dJg/dE = (2.79+/-0.02 +/- 0.5) 10^{-7} E^{-2.59 +/- 0.03 +/- 0.05}, ph m^{-2} s^{-1} TeV^{-1} The Crab Nebula energy spectrum, as measured with the HEGRA IACT system, agrees within 15% in the absolute scale and within 0.1 units in the power law index with the latest measurements by the Whipple, CANGAROO and CAT groups, consistent within the statistical and systematic errors quoted by the experiments. The pure power-law spectrum of TeV gamma-rays from the Crab Nebula constrains the physics parameters of the nebula environment as well as the models of photon emission.Comment: to appear in ApJ, 29 pages, 6 figure

    Observations of H1426+428 with HEGRA -- Observations in 2002 and reanalysis of 1999&2000 data

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    The HEGRA system of imaging air Cherenkov telescopes has been used to observe the BL Lac object H1426+428 (z=0.129z=0.129) for 217.5 hours in 2002. In this data set alone, the source is detected at a confidence level of 5.3 σ5.3~\sigma, confirming this object as a TeV source. The overall flux level during the observations in 2002 is found to be a factor of 2.5\approx 2.5 lower than during the previous observations by HEGRA in 1999&2000. A new spectral analysis has been carried out, improving the signal-to-noise ratio at the expense of a slightly increased systematic uncertainty and reducing the relative energy resolution to ΔE/E12\Delta E/E\le 12 % over a wide range of energies. The new method has also been applied to the previously published data set taken in 1999 and 2000, confirming the earlier claim of a flattening of the energy spectrum between 1 and 5 TeV. The data set taken in 2002 shows again a signal at energies above 1 TeV. We combine the energy spectra as determined by the CAT and VERITAS groups with our reanalyzed result of the 1999&2000 data set and apply a correction to account for effects of absorption of high energy photons on extragalactic background light in the optical to mid infrared band. The shape of the inferred source spectrum is mostly sensitive to the characteristics of the extragalactic background light between wavelengths of 1 and 15~μ\mumComment: 12 pages, 4 Figures, submitted to A&

    A study of Tycho's SNR at TeV energies with the HEGRA CT-System

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    Tycho's supernova remnant (SNR) was observed during 1997 and 1998 with the HEGRA Cherenkov Telescope System in a search for gamma-ray emission at energies above ~1 TeV. An analysis of these data, ~65 hours in total, resulted in no evidence for TeV gamma-ray emission. The 3sigma upper limit to the gamma-ray flux (>1 TeV) from Tycho is estimated at 5.78x10^{-13} photons cm^{-2} s^{-1}, or 33 milli-Crab. We interpret our upper limit within the framework of the following scenarios: (1) that the observed hard X-ray tail is due to synchrotron emission. A lower limit on the magnetic field within Tycho may be estimated B>=22 microG, assuming that the RXTE-detected X-rays were due to synchrotron emission. However, using results from a detailed model of the ASCA emission, a more conservative lower limit B>=6 microG is derived. (2) the hadronic model of Drury, Aharonian & Voelk, and (3) the more recent time-dependent kinetic theory of Berezhko & Voelk. Our upper limit lies within the range of predicted values of both hadronic models, according to uncertainties in physical parameters of Tycho, and shock acceleration details. In the latter case, the model was scaled to suit the parameters of Tycho and re-normalised to account for a simplification of the original model. We find that we cannot rule out Tycho as a potential contributor at an average level to the Galactic cosmic-ray flux.Comment: 9 pages, 6 figures. Accepted for publication in Astronomy and Astrophysic

    Correlated intense X-ray and TeV activity of Mrk~501 in 1998 June

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    We present exactly simultaneous X-ray and TeV monitoring with {\it RXTE} and HEGRA of the TeV blazar Mrk 501 during 15 days in 1998 June. After an initial period of very low flux at both wavelengths, the source underwent a remarkable flare in the TeV and X-ray energy bands, lasting for about six days and with a larger amplitude at TeV energies than in the X-ray band. At the peak of the TeV flare, rapid TeV flux variability on sub-hour timescales is found. Large spectral variations are observed at X-rays, with the 3--20 keV photon index of a pure power law continuum flattening from Γ=2.3\Gamma=2.3 to Γ=1.8\Gamma=1.8 on a timescale of 2--3 days. This implies that during the maximum of the TeV activity, the synchrotron peak shifted to energies 50\gtrsim 50 keV, a behavior similar to that observed during the longer-lasting, more intense flare in 1997 April. The TeV spectrum during the flare is described by a power law with photon index Γ=1.9\Gamma=1.9 and an exponential cutoff at \sim 4 TeV; an indication for spectral softening during the flare decay is observed in the TeV hardness ratios. Our results generally support a scenario where the TeV photons are emitted via inverse Compton scattering of ambient seed photons by the same electron population responsible for the synchrotron X-rays. The simultaneous spectral energy distributions (SEDs) can be fit with a one-zone synchrotron-self Compton model assuming a substantial increase of the magnetic field and the electron energy by a factor of 3 and 10, respectively.Comment: Accepted for publication in ApJ, Part

    TeV Gamma-ray Observations of the Crab and Mkn 501 during Moonshine and Twilight

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    TeV Gamma-ray signals from the Crab Nebula and Mkn 501 were detected with the HEGRA CT1 imaging Cerenkov telescope during periods when the moon was shining and during twilight. This was accomplished by lowering the high voltage supply of the photomutipliers in fixed steps up to 13%. No other adjustments were made and no filters were used. Laser runs could not establish any non-linearity in the gain of the individual pixels, and the trigger rate was uniform over the whole camera. The energy threshol was increased by up to a factor of two, depending on the amount of HV reduction. In a series of observations lasting 11.7 hours, a signal with a 3.4 sigma significance was detected from the Crab. During the 1997 multiple flare episode of Mkn 501 a 26 sigma combined excess has been recorded during 134 hours of observations under various moonshine/twilight conditions. The results show that this technique can easily be adapted to increase the exposure of a source, which is important for sources showing rapid time variability such as AGNs or GRBs. Observations can be made up to ~20 deg. angular separation from the moon and until the moon is 85% illuminated (ten to eleven days before and after new moon), as well as during 20 to 40 minutes during twilight, before the commencement of astronomical darkness.Comment: 16 pages, 5 figures, submitted to Astroparticle Physic
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