Implementasi Perjanjian Kerja Antara Karyawan Dengan PT. Kusumahadi Santosa Di Karanganyar

Implementasi perjanjian kerja adalah suatu penerapan hal-hal yang ada dalam perjanjian, yang disepakati oleh para pihak dalam isi surat perjanjian kerja, suatu perjanjian kerja tersebut yang dibuat oleh para pihak secara tertulis sebelum terjadinya kesepakatan masing-masing para pihak, perjanjian kerja secara tertulis ini sebagai media perikatan dan alat bukti untuk para pihak yang berkepentingan. Sehingga setelah terjadi kesepakatan dalam perjanjian kerja antara para pihak tersebut maka timbulhah hubungan hukum yang berisi hak dan kewajiban bagi para pihak dalam perjanjian kerja tersebut yang harus dipenuhi oleh para pihak dalam perjanjian tersebut. Perjanjian kerja dalam Undangundang No. 13 Tahun 2003 Tentang Ketenagakerjaan, Pasal 1 angka 14 yang menyatakan bahwa “perjanjian kerja adalah perjanjian antara pekerja / buruh dan pengusaha atau pemberi kerja yang memuat syarat-syarat kerja, hak, kewajiban para pihak”. Sebagai contoh implementasi perjanjian kerja antara karyawan dengan pt. Kusumahadi Santosa di karanganyar. Dalam penerapan perjanjian kerja antara karyawan dengan PT. Kusumahadi Santosa dari hasil penelitian bahwa implementasi perjanjian kerja, hak dan kewajiban para pihak, peraturan-peraturan yang berlaku diperusahaan dan pertangung-jawaban apabila salah satu pihak melakukan wansprestai dan pelanggaran hukum dalam perjanjian kerja antara karyawan dengan PT. Kusumahadi di karanganyar. Perjanjian Kerja tersebut telah dianalisis berdasarkan Undang-undang Nomor 13 tahun 2003 tentang Ketenagakerjaan

Economic Valuation of Mangrove Forest Ecosystem in Waidoba Island, South Kayoa District, South Halmahera Regency

Mangrove Forest ecosystems have distinctive characteristics and forms and have functions and benefits as development resources both as economic resources and ecological resources that have long been felt by the Indonesian people, especially for the people who live around that area. This research aims to identify the types of utilization of mangrove forest ecosystems and to analyze the total economic value of mangrove forest ecosystems in the area of Waidoba Island, South Kayoa District, South Halmahera Regency. The sampling method in this study used a purposive sampling method. Based on the results identification of the benefits and functions of the mangrove forest ecosystem in Waidoba Island area, Kayoa Selatan District, that there were (4) four types of mangrove forest ecosystem benefits, namely (1) direct benefits (2) indirect benefits, (3) optional benefits and (4) benefits of existence. While the results of costs and benefits of the total economic value of mangrove forest ecosystem in Waidoba Island area of South Kayoa District were obtained Rp. Rp.170.520.720.104/year or Rp.418.014.659,-/ha/year. This total economic value was the benefit value of mangrove forest ecosystem that utilized by the community covering an area of 407.93 Ha

Upaya Peningkatan Pengetahuan Siswa Tentang Pentingnya Mitigasi Bencana di Desa Hutamonu, Kecamatan Botumoito, Kabupaten Boalemo

Abstract Indonesia is a country that has a high level of disaster risk. Community preparedness efforts, especially for children, are still lacking, marked by the number of victims of natural disasters which is still very high, with this effort increasing knowledge about disaster mitigation is still very important for the community. This service aims to increase public knowledge, especially students, about disaster mitigation efforts, through outreach activities in several schools. The results of the service show that the level of student knowledge about disaster mitigation is still very lacking and needs to be improved. It is hoped that further actions such as maintenance and supervision as control with the aim of these activities have optimal results to increase students' knowledge about disaster mitigation and the realization of disaster resilient schools.Keywords: Disaster Mitigation, Socialization , Disaster Resilient

Pemanfaatan Buah Mangrove Rhizophora apiculata Sebagai Olahan Kopi Mangrove Dalam Upaya Peningkatan Ekonomi Masyarakat Di Desa Maitara Utara Kecamatan Tidore Utara

The use of mangrove fruit as food and beverage ingredients has never been carried out by the people of Maitara Island, Tidore City Islands. The problems faced by the community are: low public knowledge about the benefits of mangrove fruit as a food and beverage ingredient, lack of public knowledge about the diversification of processed mangrove fruit products as an ingredient in mangrove coffee drinks and low knowledge of good quality mangrove coffee powder processing techniques. The objectives of the PKM activities are: partners can find out about the benefits of mangrove fruit as food and beverage ingredients, apply appropriate technology in mangrove coffee powder processing techniques with good quality and get quality mangrove coffee variants and have high selling value to increase partner's economic income. The results of PKM activities are the diversification of Rhizophora apiculata processed mangrove fruit products as mangrove coffee drink ingredients that have a selling value so that they can improve people's welfare, the mangrove fruit calyx produces finer and denser coffee powder, coffee powder can be served in various variants, namely Sory (original soki ), SoSweet (sweet soki) and Pelakor (spice coffee customer) and all are liked by the public and organoleptic test results, all types of coffee variants are liked by researchers and the Pelakor variant is the variant that has a higher scoring value

Clinical effectiveness and cost-effectiveness of pegvisomant for the treatment of acromegaly: a systematic review and economic evaluation

Background: Acromegaly, an orphan disease usually caused by a benign pituitary tumour, is characterised by hyper-secretion of growth hormone (GH) and insulin-like growth factor I (IGF-1). It is associated with reduced life expectancy, cardiovascular problems, a variety of insidiously progressing detrimental symptoms and metabolic malfunction. Treatments include surgery, radiotherapy and pharmacotherapy. Pegvisomant (PEG) is a genetically engineered GH analogue licensed as a third or fourth line option when other treatments have failed to normalise IGF-1 levels. Methods: Evidence about effectiveness and cost-effectiveness of PEG was systematically reviewed. Data were extracted from published studies and used for a narrative synthesis of evidence. A decision analytical economic model was identified and modified to assess the cost-effectiveness of PEG. Results: One RCT and 17 non-randomised studies were reviewed for effectiveness. PEG substantially reduced and rapidly normalised IGF-1 levels in the majority of patients, approximately doubled GH levels, and improved some of the signs and symptoms of the disease. Tumour size was unaffected at least in the short term. PEG had a generally safe adverse event profile but a few patients were withdrawn from treatment because of raised liver enzymes. An economic model was identified and adapted to estimate the lower limit for the cost-effectiveness of PEG treatment versus standard care. Over a 20 year time horizon the incremental cost-effectiveness ratio was pound81,000/QALY and pound212,000/LYG. To reduce this to pound30K/QALY would require a reduction in drug cost by about one third. Conclusion: PEG is highly effective for improving patients' IGF-1 level. Signs and symptoms of disease improve but evidence is lacking about long term effects on improved signs and symptoms of disease, quality of life, patient compliance and safety. Economic evaluation indicated that if current standards (UK) for determining cost-effectiveness of therapies were to be applied to PEG it would be considered not to represent good value for money

Combining Free Text and Structured Electronic Medical Record Entries to Detect Acute Respiratory Infections

The electronic medical record (EMR) contains a rich source of information that could be harnessed for epidemic surveillance. We asked if structured EMR data could be coupled with computerized processing of free-text clinical entries to enhance detection of acute respiratory infections (ARI).A manual review of EMR records related to 15,377 outpatient visits uncovered 280 reference cases of ARI. We used logistic regression with backward elimination to determine which among candidate structured EMR parameters (diagnostic codes, vital signs and orders for tests, imaging and medications) contributed to the detection of those reference cases. We also developed a computerized free-text search to identify clinical notes documenting at least two non-negated ARI symptoms. We then used heuristics to build case-detection algorithms that best combined the retained structured EMR parameters with the results of the text analysis.An adjusted grouping of diagnostic codes identified reference ARI patients with a sensitivity of 79%, a specificity of 96% and a positive predictive value (PPV) of 32%. Of the 21 additional structured clinical parameters considered, two contributed significantly to ARI detection: new prescriptions for cough remedies and elevations in body temperature to at least 38°C. Together with the diagnostic codes, these parameters increased detection sensitivity to 87%, but specificity and PPV declined to 95% and 25%, respectively. Adding text analysis increased sensitivity to 99%, but PPV dropped further to 14%. Algorithms that required satisfying both a query of structured EMR parameters as well as text analysis disclosed PPVs of 52-68% and retained sensitivities of 69-73%.Structured EMR parameters and free-text analyses can be combined into algorithms that can detect ARI cases with new levels of sensitivity or precision. These results highlight potential paths by which repurposed EMR information could facilitate the discovery of epidemics before they cause mass casualties

Global overview of the management of acute cholecystitis during the COVID-19 pandemic (CHOLECOVID study)

Background: This study provides a global overview of the management of patients with acute cholecystitis during the initial phase of the COVID-19 pandemic. Methods: CHOLECOVID is an international, multicentre, observational comparative study of patients admitted to hospital with acute cholecystitis during the COVID-19 pandemic. Data on management were collected for a 2-month study interval coincident with the WHO declaration of the SARS-CoV-2 pandemic and compared with an equivalent pre-pandemic time interval. Mediation analysis examined the influence of SARS-COV-2 infection on 30-day mortality. Results: This study collected data on 9783 patients with acute cholecystitis admitted to 247 hospitals across the world. The pandemic was associated with reduced availability of surgical workforce and operating facilities globally, a significant shift to worse severity of disease, and increased use of conservative management. There was a reduction (both absolute and proportionate) in the number of patients undergoing cholecystectomy from 3095 patients (56.2 per cent) pre-pandemic to 1998 patients (46.2 per cent) during the pandemic but there was no difference in 30-day all-cause mortality after cholecystectomy comparing the pre-pandemic interval with the pandemic (13 patients (0.4 per cent) pre-pandemic to 13 patients (0.6 per cent) pandemic; P = 0.355). In mediation analysis, an admission with acute cholecystitis during the pandemic was associated with a non-significant increased risk of death (OR 1.29, 95 per cent c.i. 0.93 to 1.79, P = 0.121). Conclusion: CHOLECOVID provides a unique overview of the treatment of patients with cholecystitis across the globe during the first months of the SARS-CoV-2 pandemic. The study highlights the need for system resilience in retention of elective surgical activity. Cholecystectomy was associated with a low risk of mortality and deferral of treatment results in an increase in avoidable morbidity that represents the non-COVID cost of this pandemic