202 research outputs found
Imaging of Magnetic Microstructures at Surfaces: The Scanning Electron Microscope with Spin Polarization Analysis
The scanning electron microscope with spin polarization analysis of secondary electrons has been proven to be a powerful tool for studying magnetic microstructures. Secondary electrons created at the surface of a ferromagnet are spin-polarized and contain information about the sample magnetization and its orientation. The combination of a spin polarization analyzer with a scanning electron microscope yields an unique apparatus for probing magnetic properties on a very small lateral scale. The magnetic resolution of \u3c 40 nm is demonstrated. This type of microscope provides high magnetic contrast, while the surface morphology is strongly or even totally suppressed. The capability of studying magnetic properties of semi- infinite samples as well as in ultrathin films is demonstrated with a Fe(lOO) single crystal, video tape, CoCr perpendicular recording medium and ultrathin cobalt films
Characterization of Spatial Coherence of Synchrotron Radiation with Non-Redundant Arrays of Apertures
We present a method to characterize the spatial coherence of soft X-ray
radiation from a single diffraction pattern. The technique is based on
scattering from non-redundant arrays (NRA) of slits and records the degree of
spatial coherence at several relative separations from one to 15 microns,
simultaneously. Using NRAs we measured the transverse coherence of the X-ray
beam at the XUV X-ray beamline P04 of the PETRA III synchrotron storage ring as
a function of different beam parameters. To verify the results obtained with
the NRAs additional Young's double pinhole experiments were conducted and show
good agreement.Comment: 15 pages, 6 figures, 2 tables, 42 reference
Anisotropic susceptibility of ferromagnetic ultrathin Co films on vicinal Cu
We measure the magnetic susceptibility of ultrathin Co films with an in-plane
uniaxial magnetic anisotropy grown on a vicinal Cu substrate. Above the Curie
temperature the influence of the magnetic anisotropy can be investigated by
means of the parallel and transverse susceptibilities along the easy and hard
axes. By comparison with a theoretical analysis of the susceptibilities we
determine the isotropic exchange interaction and the magnetic anisotropy. These
calculations are performed in the framework of a Heisenberg model by means of a
many-body Green's function method, since collective magnetic excitations are
very important in two-dimensional magnets.Comment: 7 pages, 3 figure
Enhanced Magneto-Optical Edge Excitation in Nanoscale Magnetic Disks
We report unexpected enhancements of the magneto-optical effect in ferromagnetic Permalloy disks of diameter D < 400 nm. The effect becomes increasingly pronounced for smaller D, reaching more than a 100% enhancement for D ¼ 100 nm samples. By means of experiments and simulations, the origin of this effect is identified as a nanoscale ring-shaped region at the disk edges, in which the magneto-optically induced electric polarization is enhanced. This leads to a modification of the electromagnetic near fields and causes the enhanced magneto-optical excitation, independent from any optical resonance.We acknowledge funding from the Basque Government
(Program No. PI2012-47) and the Spanish Government
(Project No.MAT2012-36844).Work at the Universidad de
Cantabria has been supported by MICINN under Project
No. FIS2013-45854-P
Cost of antipsychotic polypharmacy in the treatment of schizophrenia
<p>Abstract</p> <p>Background</p> <p>This study compared the costs of antipsychotic polypharmacy for patients who initiated on 1 of the 3 most commonly prescribed atypical antipsychotics – olanzapine, quetiapine, or risperidone.</p> <p>Methods</p> <p>Data were drawn from a large, prospective, naturalistic, multi-site, nonrandomized study of treatment for schizophrenia in the United States conducted between July 1997 and September 2003. Participants who were initiated on olanzapine (N = 405), quetiapine (N = 115), or risperidone (N = 276) were followed for 1 year post initiation and compared on: (a) average daily cost of the index antipsychotic while on the index antipsychotic, (b) average daily cost of the coprescribed antipsychotics while on the index antipsychotic, (c) average daily cost of the index antipsychotic and the coprescribed antipsychotics while on the index antipsychotic, (d) total annual cost of antipsychotic medications prescribed in the year following initiation on the index antipsychotic, using propensity score-adjusted bootstrap resampling method. Average daily antipsychotic costs and total annual antipsychotic costs were also estimated using more recent (2004) antipsychotic drug prices.</p> <p>Results</p> <p>During the 1 year following initiation on the index antipsychotic, the total average daily cost of the index antipsychotic was higher for quetiapine (13.90, p < .05) and risperidone (10.08) than risperidone (6.63, p < .01). Lower total average daily costs were observed in risperidone than olanzapine or quetiapine. Significantly lower average daily cost of concomitant antipsychotic medications for olanzapine (8.70, p < .01) or risperidone-initiated patients (1.31 on concomitant antipsychotics for quetiapine compared to 0.38 for olanzapine-initiated patients. A separate intent-to-treat analysis of the total annual antipsychotic cost found a significantly higher total annual antipsychotic cost for quetiapine-initiated patients (4536, p < .01) or risperidone ($3813, p < .01).</p> <p>Conclusion</p> <p>Prevalent antipsychotic polypharmacy adds substantial cost to the treatment of schizophrenia. Comparison of medication costs need to address the costs of all antipsychotics. A better understanding of concomitant antipsychotic costs provides a more accurate portrayal of antipsychotic medication costs in the treatment of schizophrenia.</p
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