419 research outputs found

    Switching noise as a probe of statistics in the fractional quantum Hall effect

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    We propose an experiment to probe the unconventional quantum statistics of quasi-particles in fractional quantum Hall states by measurement of current noise. The geometry we consider is that of a Hall bar where two quantum point contacts introduce two interfering amplitudes for back-scattering. Thermal fluctuations of the number of quasi-particles enclosed between the two point contacts introduce current noise, which reflects the statistics of the quasi-particles. We analyze abelian ν=1/q\nu=1/q states and the non-abelian ν=5/2\nu=5/2 state

    Weddell Sea iceberg drift: Five years of observations

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    Since 1999, 52 icebergs have been tagged with GPS buoys in the Weddell Seato enable monitoring of their position. The chosen icebergs were of small tomedium size, with a few icebergs larger than 10 km associatedwith the calving of icebergs A38 and A43 from the Ronne Ice Shelf.The majority of icebergs were tagged off Neumayer Station (8E, 70S).It was found that smaller bergs with edges shorter than 200 m had the shortestlife cycle (< 0.5 yr). Iceberg and thus freshwater export out of theWeddell Sea was found to be highly variable. In one year the majority of buoysdeployed remained in the Weddell Sea, constituting about 40 % of the NCEP P-Efreshwater input, whereas in other years all of the tagged icebergs were exported.The observed drifts of icebergs and sea-ice showed a remarkably coherent motion.The analysis of an iceberg - sea-ice buoy array in the western Weddell Seaand an iceberg array in the eastern Weddell Sea showed a coherent sea-iceiceberg drift in sea-ice concentrations above 86 %. Dynamic kinematic parameter(DKP) during the course of coherent movement were low and deviations from the meancourse associated with the passage of low-pressure system. The length scale ofcoherent movement was estimated to be less than 250km; about half the value found forthe Arctic Ocean

    К всеобщим свойствам экономического пространства: науковедческий анализ

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    Определяются всеобщие свойства экономического пространства. Сделана попытка осмыслить современные тенденции в развитии экономической науки. Рассматриваются общие проблемы состояния и развития мировой экономики, ее глобализации.Визначено загальні властивості економічного простору. Зроблено спробу осмислити сучасні тенденції у поступі економічної науки. Розглядаються загальні проблеми стану та розвитку світової економіки, її глобалізації.The paper outlines general features of an economic area. A try is made to rethink latest tendencies in the stride of economic science. Also, broad problems related with the performance and globalization of worldwide economics are discussed

    Signs and symptoms of temporomandibular disorders and oral parafunctions in urban Saudi arabian adolescents: a research report

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    BACKGROUND: The aim of this study was to evaluate the prevalence of signs and symptoms of temporomandibular disorders (TMD) and oral parafunction habits among Saudi adolescents in the permanent dentition stage. METHODS: A total of 385 (230 females and 155 males) school children age 12–16, completed a questionnaire and were examined clinically. A stratified selection technique was used for schools allocation. RESULTS: The results showed that 21.3% of the subjects exhibited at least one sign of TMD and females were generally more affected than males. Joint sounds were the most prevalent sign (13.5%) followed by restricted opening (4.7%) and opening deviation (3.9%). The amplitude of mouth opening, overbite taken into consideration, was 46.5 mm and 50.2 mm in females and males respectively. TMJ pain and muscle tenderness were rare (0.5%). Reported symptoms were 33%, headache being the most frequent symptom 22%, followed by pain during chewing 14% and hearing TMJ noises 8.7%. Difficulty during jaw opening and jaw locking were rare. Lip/cheek biting was the most common parafunction habit (41%) with females significantly more than males, followed by nail biting (29%). Bruxism and thumb sucking were only 7.4% and 7.8% respectively. CONCLUSION: The prevalence of TMD signs were 21.3% with joint sounds being the most prevalent sign. While TMD symptoms were found to be 33% as, with headache being the most prevalent. Among the oral parafunctions, lip/cheek biting was the most prevalent 41% followed by nail biting 29%

    Basal melt and freezing rates from first noble gas samples beneath an ice shelf

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    A climatically‐induced acceleration in ocean‐driven melting of Antarctic ice shelves would have consequences for both the discharge of continental ice into the ocean and thus global sea level, and for the formation of Antarctic Bottom Water and the oceanic meridional overturning circulation. Using a novel gas‐tight in‐situ water sampler, noble gas samples have been collected from six locations beneath the Filchner Ice Shelf, the first such samples from beneath an Antarctic Ice shelf. Helium and neon are uniquely suited as tracers of glacial meltwater in the ocean. Basal meltwater fractions range from 3.6% near the ice shelf base to 0.5% near the sea floor, with distinct regional differences. We estimate an average basal melt rate for the Filchner‐Ronne Ice Shelf of 177 ± 95 Gt/year, independently confirming previous results. We calculate that up to 2.7% of the meltwater has been refrozen, and we identify a local source of crustal helium

    Inactivation of respiratory syncytial virus by zinc finger reactive compounds

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    <p>Abstract</p> <p>Background</p> <p>Infectivity of retroviruses such as HIV-1 and MuLV can be abrogated by compounds targeting zinc finger motif in viral nucleocapsid protein (NC), involved in controlling the processivity of reverse transcription and virus infectivity. Although a member of a different viral family (<it>Pneumoviridae</it>), respiratory syncytial virus (RSV) contains a zinc finger protein M2-1 also involved in control of viral polymerase processivity. Given the functional similarity between the two proteins, it was possible that zinc finger-reactive compounds inactivating retroviruses would have a similar effect against RSV by targeting RSV M2-1 protein. Moreover, inactivation of RSV through modification of an internal protein could yield a safer whole virus vaccine than that produced by RSV inactivation with formalin which modifies surface proteins.</p> <p>Results</p> <p>Three compounds were evaluated for their ability to reduce RSV infectivity: 2,2'-dithiodipyridine (AT-2), tetraethylthiuram disulfide and tetramethylthiuram disulfide. All three were capable of inactivating RSV, with AT-2 being the most potent. The mechanism of action of AT-2 was analyzed and it was found that AT-2 treatment indeed results in the modification of RSV M2-1. Altered intramolecular disulfide bond formation in M2-1 protein of AT-2-treated RSV virions might have been responsible for abrogation of RSV infectivity. AT-2-inactivated RSV was found to be moderately immunogenic in the cotton rats <it>S.hispidus </it>and did not cause a vaccine-enhancement seen in animals vaccinated with formalin-inactivated RSV. Increasing immunogenicity of AT-2-inactivated RSV by adjuvant (Ribi), however, led to vaccine-enhanced disease.</p> <p>Conclusions</p> <p>This work presents evidence that compounds that inactivate retroviruses by targeting the zinc finger motif in their nucleocapsid proteins are also effective against RSV. AT-2-inactivated RSV vaccine is not strongly immunogenic in the absence of adjuvants. In the adjuvanted form, however, vaccine induces immunopathologic response. The mere preservation of surface antigens of RSV, therefore may not be sufficient to produce a highly-efficacious inactivated virus vaccine that does not lead to an atypical disease.</p
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