96 research outputs found
A Decathlon in Multidimensional Modeling: Open Issues and Some Solutions
The concept of multidimensional modeling has proven extremely successful in the area of Online Analytical Processing (OLAP) as one of many applications running on top of a data warehouse installation. Although many different modeling techniques expressed in extended multidimensional data models were proposed in the recent past, we feel that many hot issues are not properly reflected. In this paper we address ten common problems reaching from defects within dimensional structures over multidimensional structures to new analytical requirements and more
Cavity-enhanced Raman Microscopy of Individual Carbon Nanotubes
Raman spectroscopy reveals chemically specific information and provides
label-free insight into the molecular world. However, the signals are
intrinsically weak and call for enhancement techniques. Here, we demonstrate
Purcell enhancement of Raman scattering in a tunable high-finesse microcavity,
and utilize it for molecular diagnostics by combined Raman and absorption
imaging. Studying individual single-wall carbon nanotubes, we identify crucial
structural parameters such as nanotube radius, electronic structure and
extinction cross-section. We observe a 320-times enhanced Raman scattering
spectral density and an effective Purcell factor of 6.2, together with a
collection efficiency of 60%. Potential for significantly higher enhancement,
quantitative signals, inherent spectral filtering and absence of intrinsic
background in cavity-vacuum stimulated Raman scattering render the technique a
promising tool for molecular imaging. Furthermore, cavity-enhanced Raman
transitions involving localized excitons could potentially be used for gaining
quantum control over nanomechanical motion and open a route for molecular
cavity optomechanics
Weak and Strong coupling regimes in plasmonic-QED
We present a quantum theory for the interaction of a two level emitter with
surface plasmon polaritons confined in single-mode waveguide resonators. Based
on the Green's function approach, we develop the conditions for the weak and
strong coupling regimes by taking into account the sources of dissipation and
decoherence: radiative and non-radiative decays, internal loss processes in the
emitter, as well as propagation and leakage losses of the plasmons in the
resonator. The theory is supported by numerical calculations for several
quantum emitters, GaAs and CdSe quantum dots and NV centers together with
different types of resonators constructed of hybrid, cylindrical or wedge
waveguides. We further study the role of temperature and resonator length.
Assuming realistic leakage rates, we find the existence of an optimal length at
which strong coupling is possible. Our calculations show that the strong
coupling regime in plasmonic resonators is accessible within current technology
when working at very low temperatures (<4K). In the weak coupling regime our
theory accounts for recent experimental results. By further optimization we
find highly enhanced spontaneous emission with Purcell factors over 1000 at
room temperature for NV-centers. We finally discuss more applications for
quantum nonlinear optics and plasmon-plasmon interactions.Comment: published as Phys. Rev. B 87, 115419 (2013
Simplified models for photohadronic interactions in cosmic accelerators
We discuss simplified models for photo-meson production in cosmic
accelerators, such as Active Galactic Nuclei and Gamma-Ray Bursts. Our
self-consistent models are directly based on the underlying physics used in the
SOPHIA software, and can be easily adapted if new data are included. They allow
for the efficient computation of neutrino and photon spectra (from pi^0
decays), as a major requirement of modern time-dependent simulations of the
astrophysical sources and parameter studies. In addition, the secondaries
(pions and muons) are explicitely generated, a necessity if cooling processes
are to be included. For the neutrino production, we include the helicity
dependence of the muon decays which in fact leads to larger corrections than
the details of the interaction model. The separate computation of the pi^0,
pi^+, and pi^- fluxes allows, for instance, for flavor ratio predictions of the
neutrinos at the source, which are a requirement of many tests of neutrino
properties using astrophysical sources. We confirm that for charged pion
generation, the often used production by the Delta(1232)-resonance is typically
not the dominant process in Active Galactic Nuclei and Gamma-Ray Bursts, and we
show, for arbitrary input spectra, that the number of neutrinos are
underestimated by at least a factor of two if they are obtained from the
neutral to charged pion ratio. We compare our results for several levels of
simplification using isotropic synchrotron and thermal spectra, and we
demonstrate that they are sufficiently close to the SOPHIA software.Comment: Treatment of high energy interactions refined, additional black body
benchmark added (v2), some references corrected (v3). A Mathematica notebook
which illustrates the implementation of one model can be found at
http://theorie.physik.uni-wuerzburg.de/~winter/Resources/AstroModel/Sim-B.html
. 46 pages, 14 (color) figures, 7 tables. Final version, accepted for
publication in Ap
Transverse-mode coupling and diffraction loss in tunable Fabry-Perot microcavities
We report on measurements and modeling of the mode structure of tunable Fabry-Perot optical microcavities with imperfect mirrors. We find that non-spherical mirror shape and finite mirror size leave the fundamental mode mostly unaffected, but lead to loss, mode deformation, and shifted resonance frequencies at particular mirror separations. For small mirror diameters, the useful cavity length is limited to values significantly below the expected stability range. We explain the observations by resonant coupling between different transverse modes of the cavity and mode-dependent diffraction loss. A model based on resonant state expansion that takes into account the measured mirror profile can reproduce the measurements and identify the parameter regime where detrimental effects of mode mixing are avoided
Sources of UHECRs in view of the TUS and JEM-EUSO experiments
The origin of ultra-high-energy cosmic rays (UHECRs) is one of the most
intriguing problems of modern cosmic ray physics. We briefly review the main
astrophysical models of their origin and the forthcoming orbital experiments
TUS and JEM-EUSO, and discuss how the new data can help one solve the
long-standing puzzle.Comment: 4 pages; prepared for ECRS-2012 (http://ecrs2012.sinp.msu.ru/); v2: a
reference adde
Cdk1 inactivation terminates mitotic checkpoint surveillance and stabilizes kinetochore attachments in anaphase
Two mechanisms safeguard the bipolar attachment of chromosomes in mitosis. A correction mechanism destabilizes erroneous attachments that do not generate tension across sister kinetochores [1]. In response to unattached kinetochores, the mitotic checkpoint delays anaphase onset by inhibiting the anaphase-promoting complex/cyclosome (APC/CCdc20) [2]. Upon satisfaction of both pathways, the APC/CCdc20 elicits the degradation of securin and cyclin B [3]. This liberates separase triggering sister chromatid disjunction and inactivates cyclin-dependent kinase 1 (Cdk1) causing mitotic exit. How eukaryotic cells avoid the engagement of attachment monitoring mechanisms when sister chromatids split and tension is lost at anaphase is poorly understood [4]. Here we show that Cdk1 inactivation disables mitotic checkpoint surveillance at anaphase onset in human cells. Preventing cyclin B1 proteolysis at the time of sister chromatid disjunction destabilizes kinetochore-microtubule attachments and triggers the engagement of the mitotic checkpoint. As a consequence, mitotic checkpoint proteins accumulate at anaphase kinetochores, the APC/CCdc20 is inhibited, and securin reaccumulates. Conversely, acute pharmacological inhibition of Cdk1 abrogates the engagement and maintenance of the mitotic checkpoint upon microtubule depolymerization. We propose that the simultaneous destruction of securin and cyclin B elicited by the APC/CCdc20 couples chromosome segregation to the dissolution of attachment monitoring mechanisms during mitotic exit
Cavity-enhanced Raman microscopy of individual carbon nanotubes
Raman spectroscopy reveals chemically specific information and provides label-free insight into the molecular world. However, the signals are intrinsically weak and call for enhancement techniques. Here, we demonstrate Purcell enhancement of Raman scattering in a tunable high-finesse microcavity, and utilize it for molecular diagnostics by combined Raman and absorption imaging. Studying individual single-wall carbon nanotubes, we identify crucial structural parameters such as nanotube radius, electronic structure and extinction cross-section. We observe a 320-times enhanced Raman scattering spectral density and an effective Purcell factor of 6.2, together with a collection efficiency of 60%. Potential for significantly higher enhancement, quantitative signals, inherent spectral filtering and absence of intrinsic background in cavity-vacuum stimulated Raman scattering render the technique a promising tool for molecular imaging. Furthermore, cavity-enhanced Raman transitions involving localized excitons could potentially be used for gaining quantum control over nanomechanical motion and open a route for molecular cavity optomechanics
- …