The complete genome sequence of Chromobacterium violaceum reveals remarkable and exploitable bacterial adaptability

Chromobacterium violaceum is one of millions of species of free-living microorganisms that populate the soil and water in the extant areas of tropical biodiversity around the world. Its complete genome sequence reveals (i) extensive alternative pathways for energy generation, (ii) ≈500 ORFs for transport-related proteins, (iii) complex and extensive systems for stress adaptation and motility, and (iv) wide-spread utilization of quorum sensing for control of inducible systems, all of which underpin the versatility and adaptability of the organism. The genome also contains extensive but incomplete arrays of ORFs coding for proteins associated with mammalian pathogenicity, possibly involved in the occasional but often fatal cases of human C. violaceum infection. There is, in addition, a series of previously unknown but important enzymes and secondary metabolites including paraquat-inducible proteins, drug and heavy-metal-resistance proteins, multiple chitinases, and proteins for the detoxification of xenobiotics that may have biotechnological applications

Developing a nursing graduate follow-up methodology for a higher education institution

The purpose of this study was to describe the development and implementation of an online graduate follow-up method to keep an updated database of the institution’s former students. It was a descriptive study of a population of nursing graduates from a higher education institution. This electronic instrument was available at the institution’s website, where the graduates provide their data in a survey. The pilot method with graduates from 2011 was used for method validation. In total, 53.65% answered the questionnaire in a first approach through email in a six-month period. The preliminary results confirm that the platform can be applied to the proposed objective. The graduate follow-up method allows access to assessment tools for institutions to evaluate the impact of graduation on healthcare services

La couverture médiatique de la REDD+

<div><p>Abstract Introduction The Brazilian National Program for Improving Access and Quality of Primary Care aims to induce the institution of processes that expand the capacity of federal, state and municipal administrations and Primary Care teams to offer services that ensure greater access and quality. Objective To identify the characteristics of infrastructure for the dental health care of the health units from the Regional Health Care Network 13, from the perspective of a health evaluation. Material and method This is a descriptive and cross-sectional study in which is used the Module V database of the External Evaluation instrument of 156 health units of this region that participated of the 2nd cycle of the referred program, which discuss the modality of the health teams, structure and environment of the dental office, the hours of operation, equipment, instruments and dental supplies. Result In general, the oral health units of this study have dental offices with good structural conditions and sufficient equipment and supplies to carry out clinical activities, except those for dental prostheses, possibly due to the permanence of this service in secondary care. However, they point out that advances in access and coverage by oral health services are still necessary. Conclusion Although the theme includes other studies and reflections, the present work may contribute to discussions about the present condition, and it is recommended the active participation of all the actors involved in the care, in the search for the qualification of oral health services in this region.</p></div

Social participation in Primary Health Care towards the 2030 Agenda

<p></p><p>Abstract Listening to society is an ethical reference to respond to its legitimate needs and aspirations. Considering as presuppositions the social participation and the right to the city, which are part of the 2030 Agenda, this study sought to recognize the voice of users that evaluated PHC services and their attributes. This descriptive and cross-sectional study used national ministerial evaluation data, outlining a region with 323 teams in 80 municipalities in the state of São Paulo and 1,272 users heard by authors. Users were mostly female, over 51 years old, with low income and schooling, eliciting challenges to population aging and selective care. Around 93% were 20 minutes away from health services and opening on Saturdays (43%) and at night (38%) would facilitate access. Some 60% were received without scheduling and 62% did not consider services prepared for urgent care. Some 85% received Community Health Workers and 40% other professionals, suggesting disparities in the incorporation of the territory to the care production process. In line with National Primary Health Care Policy and what is recommended by international conferences, social participation was recognized as a way to address the multiple aspects in the construction of universal health.</p><p></p