12 research outputs found

    Ethnobiological survey of plants and animals used for the treatment of acute respiratory infections in children of a traditional community in the Municipality of Barbalha, Ceará, Brazil

    Get PDF
    Background: The use of natural resources for the treatment of acute respiratory infections in children is a widespread practice within traditional communities, especially by women by being the primary caregivers. This study aimed to perform ethnobiological survey of plants and animals used for the treatment of acute respiratory infections in children of a traditional community in the municipality of Barbalha, Ceará, Brazil. Methods: It is a descriptive exploratory study with a quantitative approach, developed in Sítio Santo Antônio, in the municipality of Barbalha, Ceará, Brazil. As a tool for data collection, was applied a questionnaire and a semi-structured interview. Data analysis used descriptive statistics (simple and percentage rate) and the Relative Frequency of Citation.Results: The research included a total of 54 informants. In total, there were 38 species cited. According to the Relative Frequency of Citation the following species were the most cited: Ocimum basilicum L. (0.59), Eucalyptus globulus Labill (0.59), Plectranthus amboinicus (L.) Spreng (0.42), Hyptis suaveolens (L.) Poit. (0.24), Allium aescalonicum L. (0.22) and Mentha arvensis L. (0.18). Among the symptoms  mentioned by the research subjects to treat the acute respiratory infections in childhood, there were: fever; cough; coughing with secretions; sore throat;  hoarseness; tiredness; nasal congestion.Conclusions: It is important the knowledge about the usefulness of natural resources as alternative practices in diseases treatment, seeking to rescue popular knowledge used in the traditional community and fomenting the need to consider cultural aspects in the full practice to children´s health care.Keywords: Ethnobotany; Ethnomedicine; Acute respiratory infections; Natural  products; Children's Health

    Antiulcerogenic activity of the hydroalcoholic extract of leaves of Annona muricata Linnaeus in mice

    Get PDF
    AbstractAnnona muricata Linnaeus, popularly known as “graviola” and also called soursop, is a species typical of countries with a tropical climate, and it is used in folk medicine as an anticancer, analgesic and antispasmodic agent. The aim of the present study was to validate the gastroprotective activity of the hydroalcoholic extract of the leaves of A. muricata (HEAM) and to investigate the underlying mechanisms of action for this effect. Gastric lesions were induced in mice by absolute ethanol, acidified ethanol or indomethacin. Before, the animals were pretreated with saline, omeprazole or HEAM orally at doses of 50–400mg/kg. To determine the mechanism of action of the extract, we investigated, using specific inhibitors, the involvement of nitric oxide (NO), prostaglandins (PGEs), ATP-dependent K+ channels and α2-noradrenergic receptors. HEAM showed significant antiulcer activity against lesions induced by absolute ethanol, acidified ethanol or indomethacin, which was mediated by endogenous gastric prostaglandins

    Avaliação da citotoxicidade e atividade leishmanicida e tripanocida de extratos de Passiflora cincinnata Mast L.

    Get PDF
    A doença de Chagas e a leishmaniose são doenças que prevalecem em países pobres. Os fármacos disponíveis para o tratamento dessas doenças são altamente tóxicos, sendo este um dos motivos que dificulta à adesão terapêutica e, assim, levando à busca por novas drogas eficazes e seguras para seus tratamentos. A pesquisa utilizando produtos naturais tem se mostrado uma alternativa na procura de novos compostos com potencial clínico-terapêutico. O gênero Passiflora possui as seguintes atividades farmacológicas centrais como calmantes, sedativas, ansiolíticas e indutor do sono e atividades antiparasitarias. A Passiflora cincinnata possui ampla distribuição pelo Brasil sendo popularmente utilizada para distúrbios de sono. Neste estudo avaliamos sua atividade antiparasitária contra Leishmania brasiliensis, Leishmania infantum e Trypanosoma cruzi, bem como sua citotoxicidade em fibroblastos. Foram testados extratos hidroalcoólicos obtidos das folhas, casca, sementes e caule em diferentes concentrações. Os extratos das folhas, casca e sementes não foram eficazes contra L. brasiliensis e T. cruzi, porém, o extrato do caule promoveu uma inibição de 29,12 % contra T. cruzi numa concentração de 500 µg/mL, entretanto o extrato da casca de P. cincinnata foi o que apresentou a melhor atividade contra as formas parasitárias de L. infantum, causando um percentual de morte >20 % nas concentrações de 250 a 1000 µg/mL. Referente à toxicidade, o extrato das folhas foi o que apresentou maior citotoxicidade, quando comparado com os demais, causando a mortalidade de 68,63 % dos fibroblastos numa concentração de 1000 µg/mL. A baixa citotoxicidade revelada abre espaço para novos estudos biológicos

    Cuidador de criança com câncer: religiosidade e espiritualidade como mecanismos de enfrentamento

    Get PDF
    Introdução: Apesar dos grandes avanços na terapia oncológica, o câncer ainda se apresenta como uma doença de diagnóstico relacionado ao medo da morte que causa sofrimento na criança afetada e sua família. Em todos os casos, os cuidadores passam por mudanças drásticas nas suas vidas e sofrem diante do tratamento da criança com câncer, assim, buscam estratégias de apoio que os ajude a enfrentar essa situação adversa. Objetivo: Investigar o papel da religiosidade e da espiritualidade como mecanismo de enfrentamento utilizado pelos cuidadores familiares diante do câncer infantil. Materiais e Métodos: O local onde foi realizada a pesquisa foi o Instituto de Apoio à Criança com Câncer, no município de Barbalha (CE). Os sujeitos foram cuidadores familiares e o instrumento para coleta de dados foi uma entrevista semiestruturada. Os dados foram analisados mediante a Análise Temática. Resultados: Os dados coletados foram aglomerados em duas categorias temáticas: a fé como fonte de apoio nos momentos delicados do tratamento e as expectativas para o término do tratamento. Discussão: Os relatos evidenciaram o uso da religiosidade e da espiritualidade como componentes inerentes ao enfrentamento do câncer infantil por cuidadores familiares. Conclusões: A busca pela religião e o uso da espiritualidade pelos cuidadores está muito presente diante do enfrentamento do câncer infantil. Desse modo, o profissional de saúde deve ser uma fonte de respeito e de apoio às crenças, à religião e aos valores dos cuidadores familiares.Cómo citar este artículo: Alves D, Silva L, Delmondes G, Lemos IC, Kerntopf MR, Albuquerque G. Cuidador de criança com câncer: religiosidade e espiritualidade como mecanismos de enfrentamento. Rev Cuid. 2016; 7(2): 1318-24. http://dx.doi.org/10.15649/cuidarte.v7i2.33

    Concepts, Beliefs, and Traditional Treatment for Childhood Seizures in a Quilombola Community in Northeastern Brazil: Analysis by the Discourse of the Collective Speech

    No full text
    Background: Non-pharmacological therapy related to traditional, magical, and/or religious treatments for managing recurrent and non-recurrent seizures in children persists in several traditional communities. The research aims to investigate the concepts, beliefs, and types of traditional treatments used for cases of seizures in children reported by residents of a quilombola community. Methods: The research took place in the quilombo community Sítio Arruda, Ceará, northeastern Brazil. The study population consisted of 19 participants, including healers, prayers, and midwives. Applied a socioeconomic form and a semi-structured interview script. For data analysis, the Discourse of the Collective Speech (DCS) technique was used. Results: For the questions asked, a total of 14 central ideas were found. The most prevalent was seizure is the most common type of disease in children (50.0%); The seizure occurs because of the fever (42.0%); In the community, we treat and prevent seizures with the use of plants (63.2%). Conclusions: The present study’s results addressed relevant issues that include valuing and understanding the traditional knowledge of the community, access to health services, and the need for clarification actions about seizures

    RECURSOS NATURAIS COMO ALTERNATIVA TERAPÊUTICA EM UMA PERSPECTIVA DE GÊNEROS E URBANIZAÇÃO

    Get PDF
    A utilização de recursos naturais com finalidades terapêuticas é uma prática consolidada em todo mundo. Em vista disso, a presente pesquisa teve por objetivo caracterizar o saber / uso de recursos naturais para o tratamento de doenças reportado por moradores de diferentes áreas na cidade de Crato, Ceará (Nordeste do Brasil). Utilizou-se do método de amostragem snow ball para composição da amostra e a partir de então, roteiros semiestruturados foram aplicados para a coleta de informações, a técnica de turnê guiada também foi empregada. Os dados foram analisados de forma qualitativa, através de nuvens de palavras, a estratégia agrupa palavras e as organiza graficamente em função da sua frequência. O enlace dos resultados demonstrou declínio de citações, de espécies medicinais e usos, demonstrando que esse conhecimento tende a ser inversamente proporcional à urbanização. Constatou-se que a amostra feminina é detentora de um vasto conhecimento empírico relacionados a recursos naturais com fins terapêuticos, sendo o uso de plantas notadamente marcante, e que, a figura feminina parece ser pouco afetada pela relação de exclusão entre os pares etnosaberes-urbanização em dimensões espaço-temporais, no entanto, tornam-se necessários novos estudos para averiguar a associação entre essas variáveis, a fim de consolidar as informações obtidas nesse estudo. Em adição, a estratégia metodológica das nuvens de palavras para sintetizar os resultados permitiu uma visualização exploratória e dinâmica das informações da pesquisa, otimizando o cunho qualitativo deste estudo

    Vasodilation promoted by (E,E)-farnesol involving ion channels in human umbilical arteries

    No full text
    Background: (E,E)-farnesol is a sesquiterpene alcohol derived from plants and animals that exhibits pharmacological properties in the cardiovascular system. However, its effects on human umbilical vessels remain unknown. Purpose: Thus, this study aims to characterize the vasodilatory effect of (E,E)-farnesol in human umbilical arteries (HUA). Study design: The tissue is obtained from pregnant women over 18 years of age, normotensive, and without prepartum complications. After collected, the tissue was segmented and dissected to remove Wharton's jelly and obtain the umbilical arteries segments. Methods: HUA segments were isolated and sectioned into rings that were subjected to isometric tension recordings in an organ bath. Results: (E,E)-farnesol (1 μmol/L to 1 mmol/L) promoted vasodilatory effect in HUA preparations, affecting basal tone, and inhibiting the electromechanical coupling induced by KCl 60 mmol/L with greater potency (EC50 225.3 μmol/L) than the pharmacomechanical coupling induced by 5-HT 10 μmol/L (EC50 363.5 μmol/L). In the absence of extracellular calcium, pharmacomechanical coupling was also abolished, and contractions induced by CaCl2 or BaCl2 were attenuated by (E,E)-farnesol indicating a possible direct inhibition of L-type VOCC as a mechanism of the vasodilatory effect. The vasodilator efficacy of (E,E)-farnesol on reduction of vasocontraction induced by the presence of tetraethylammonium (1 or 10 mmol/L), 4-aminopyridine (1 mmol/L) and glibenclamide (10 μmol/L) suggesting a possible influence of different potassium channels (BKCa, KV and KATP). Conclusion: These results suggest that (E,E)-farnesol may be a promising pharmacological candidate for obstetric hypertensive disorders

    Therapeutic Play Use in Children under the Venipucture: A Strategy for Pain Reduction

    No full text
    Abstract The instructional therapeutic play (ITP) is responsible for the child´s preparation to perform procedures such as venipuncture, reducing anxiety, fear and pain in hospitalized children undergoing painful procedures. Thus, the aim of this study is to evaluate the effectiveness of ITP to the management of pain when performing peripheral venipuncture or handling of the venous access in preschool and schoolchildren. The research is analytical, exploratory and quantitative. To measure the pain of children the Faces Pain Scale (FPS) was used. For data analysis, the Wilcoxon test was used. Before the sessions, 28.6% reported the pain score "1" or absence of pain. After the sessions, 71.4% of the sample indicated the same score. Another important issue before the ITP sessions, the score was"4", which expresses intense pain. After the sessions, 100% of children who have been assigned this face, showed improvement in pain patterns. Thus, the findings of this study corroborate previous studies that show ITP as an important tool in relieving pain presented by hospitalized children, subjected to intrusive and stressful procedures

    Antiulcerogenic activity of the hydroalcoholic extract of leaves of Annona muricata Linnaeus in mice

    No full text
    Annona muricata Linnaeus, popularly known as “graviola” and also called soursop, is a species typical of countries with a tropical climate, and it is used in folk medicine as an anticancer, analgesic and antispasmodic agent. The aim of the present study was to validate the gastroprotective activity of the hydroalcoholic extract of the leaves of A. muricata (HEAM) and to investigate the underlying mechanisms of action for this effect. Gastric lesions were induced in mice by absolute ethanol, acidified ethanol or indomethacin. Before, the animals were pretreated with saline, omeprazole or HEAM orally at doses of 50–400 mg/kg. To determine the mechanism of action of the extract, we investigated, using specific inhibitors, the involvement of nitric oxide (NO), prostaglandins (PGEs), ATP-dependent K+ channels and α2-noradrenergic receptors. HEAM showed significant antiulcer activity against lesions induced by absolute ethanol, acidified ethanol or indomethacin, which was mediated by endogenous gastric prostaglandins. Keywords: Peptic ulcer, Medicinal plants, Phytotherapy, Annon
    corecore