Pitch as a recipient, channel, and context factor affecting thought reliance and persuasion

Three experiments tested how low versus high pitch generated from sources beyond a message communicator can affect reliance on thoughts and influence recipients' attitudes. First, participants wrote positive or negative thoughts about an exam proposal (Experiments 1, 2) or their academic abilities (Experiment 3). Then, pitch from the message recipient (Experiment 1), channel (Experiment 2), or context (Experiment 3) was manipulated to be high or low. Experiment 1 showed that when participants vocally expressed their thoughts using low (vs. high) pitch, thoughts had a greater effect on attitudes toward exams. Experiment 2 revealed low (vs. high) pitch sounds from the keyboard participants used to write their thoughts produced the same effect on thought usage. Experiment 3 demonstrated that thoughts influenced attitudes more when listed while background music was low (vs. high) Pitch can influence attitudes through a meta-cognitive thought reliance process whether emerging from the recipient, channel, or context

Finishing the euchromatic sequence of the human genome

The sequence of the human genome encodes the genetic instructions for human physiology, as well as rich information about human evolution. In 2001, the International Human Genome Sequencing Consortium reported a draft sequence of the euchromatic portion of the human genome. Since then, the international collaboration has worked to convert this draft into a genome sequence with high accuracy and nearly complete coverage. Here, we report the result of this finishing process. The current genome sequence (Build 35) contains 2.85 billion nucleotides interrupted by only 341 gaps. It covers ∼99% of the euchromatic genome and is accurate to an error rate of ∼1 event per 100,000 bases. Many of the remaining euchromatic gaps are associated with segmental duplications and will require focused work with new methods. The near-complete sequence, the first for a vertebrate, greatly improves the precision of biological analyses of the human genome including studies of gene number, birth and death. Notably, the human enome seems to encode only 20,000-25,000 protein-coding genes. The genome sequence reported here should serve as a firm foundation for biomedical research in the decades ahead

The Somatic Genomic Landscape of Glioblastoma

We describe the landscape of somatic genomic alterations based on multi-dimensional and comprehensive characterization of more than 500 glioblastoma tumors (GBMs). We identify several novel mutated genes as well as complex rearrangements of signature receptors including EGFR and PDGFRA. TERT promoter mutations are shown to correlate with elevated mRNA expression, supporting a role in telomerase reactivation. Correlative analyses confirm that the survival advantage of the proneural subtype is conferred by the G-CIMP phenotype, and MGMT DNA methylation may be a predictive biomarker for treatment response only in classical subtype GBM. Integrative analysis of genomic and proteomic profiles challenges the notion of therapeutic inhibition of a pathway as an alternative to inhibition of the target itself. These data will facilitate the discovery of therapeutic and diagnostic target candidates, the validation of research and clinical observations and the generation of unanticipated hypotheses that can advance our molecular understanding of this lethal cancer

Pitch as a Recipient, Channel, and Context Factor Affecting Thought Reliance and Persuasion

Materials for three experiments submitted to PSPB associated with the manuscript entitled: Pitch as a Recipient, Channel, and Context Factor Affecting Thought Reliance and Persuasio

The Role of Vocal Affect in Persuasion: The CIVA Model

Past research has largely focused on how emotional expressions provide information about the speaker’s emotional state, but has generally neglected vocal affect’s influence over communication effectiveness. This is surprising given that other nonverbal behaviors often influence communication between individuals. In the present theory paper, we develop a novel perspective called the Contextual Influences of Vocal Affect (CIVA) model to predict and explain the psychological processes by which vocal affect may influence communication through three broad categories of process: Emotion Origin/Construal, Changing Emotions, and Communication Source Inferences. We describe research that explores potential moderators (e.g., affective/cognitive message types, message intensity), and mechanisms (e.g., emotional assimilation, attributions, surprise) shaping the effects of vocally expressed emotions on communication. We discuss when and why emotions expressed through the voice can influence the effectiveness of communication. CIVA advances theoretical and applied psychology by providing a clear theoretical account of vocal affect’s diverse impacts on communication

guyer_online_appendix – Supplemental material for Speech Rate, Intonation, and Pitch: Investigating the Bias and Cue Effects of Vocal Confidence on Persuasion

<p>Supplemental material, guyer_online_appendix for Speech Rate, Intonation, and Pitch: Investigating the Bias and Cue Effects of Vocal Confidence on Persuasion by Joshua J. Guyer, Leandre R. Fabrigar and Thomas I. Vaughan-Johnston in Personality and Social Psychology Bulletin</p

Paralinguistic Features Communicated through Voice can Affect Appraisals of Confidence and Evaluative Judgments

This article unpacks the basic mechanisms by which paralinguistic features communicated through the voice can affect evaluative judgments and persuasion. Special emphasis is placed on exploring the rapidly emerging literature on vocal features linked to appraisals of confidence (e.g., vocal pitch, intonation, speech rate, loudness, etc.), and their subsequent impact on information processing and meta-cognitive processes of attitude change. The main goal of this review is to advance understanding of the different psychological processes by which paralinguistic markers of confidence can affect attitude change, specifying the conditions under which they are more likely to operate. In sum, we highlight the importance of considering basic mechanisms of attitude change to predict when and why appraisals of paralinguistic markers of confidence can lead to more or less persuasion